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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma
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Citation:
Molec Cell. 2016:62(1)34-46. doi:10.1016/j.molcel.2016.03.013 Epub:
Not Epub Abstract:
Studying cancer metabolism gives insight into tumorigenic survival mechanisms and susceptibilities. In melanoma, we identify... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, Pandell N, Avagyan S, Brogie1 JE, van Rooijen E, Hagedorn EJ, Shyh-Chang N, White RM, David H. Price DH, Pandolfi PP, Peterlin BM, Zhou Y, Kim TH, Asara JM, Chang HY, Young YA, Zon LI. Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Molec Cell. 2016:62(1)34-46. doi:10.1016/j.molcel.2016.03.013. |
Trim69 regulates zebrafish brain development by ap-1 pathway
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Sci Rep. 2016 Apr 6;6:24034. doi: 10.1038/srep24034 Epub:
Not Epub Abstract:
Proteins belonging to the TRIM family have been implicated in a variety of cellular processes such as apoptosis,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Han R, Wang R, Zhao Q, Han Y, Zong S, Miao S, Song W, Wang L. Trim69 regulates zebrafish brain development by ap-1 pathway. Sci Rep. 2016 Apr 6;6:24034. doi: 10.1038/srep24034. |
Characterization of primary cilia during the differentiation of retinal ganglion cells in the zebrafish
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Citation:
Neural Dev. 2016;11(10) doi:10.1186/s13064-016-0064-z Epub:
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Background: Retinal ganglion cell (RGC) differentiation in vivo is a highly stereotyped process, likely resulting from the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lepanto P, Davison C, Casanova G, Badano JL, Zolessi FR. Characterization of primary cilia during the differentiation of retinal ganglion cells in the zebrafish. Neural Dev. 2016;11(10) doi:10.1186/s13064-016-0064-z. |
Knockdown of Carboxypeptidase A6 in Zebrafish Larvae Reduces Response to Seizure-Inducing Drugs and Causes Changes in the Level of mRNAs Encoding Signaling Molecules
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PLoS ONE. 2016;11(4):e0152905. doi:10.1371/journal.pone.0152905 Epub:
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Carboxypeptidase A6 (CPA6) is an extracellular matrix metallocarboxypeptidase that modulates peptide and protein function by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lopes MW, Sapio MR, Leal RB, Fricker LD. Knockdown of Carboxypeptidase A6 in Zebrafish Larvae Reduces Response to Seizure-Inducing Drugs and Causes Changes in the Level of mRNAs Encoding Signaling Molecules. PLoS ONE. 2016;11(4):e0152905. doi:10.1371/journal.pone.0152905. |
FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1
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Nat Comm. 2016;7:10953. doi:10.1038/ncomms10953 Epub:
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FOXE3 is a lens-specific transcription factor that has been associated with anterior segment ocular dysgenesis. To determine... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Khan SY, Vasanth S, Kabir F, Gottsch JD, Khan AO, Chaerkady R, Lee M-CW, Leitch CC, Ma Z, Laux J, Villasmil R, Khan SN, Riazuddin S, Akram J, Cole RN, Talbot CC, Pourmand N, Zaghloul NA, Hejtmancik JF, Riazuddin SA. FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1. Nat Comm. 2016;7:10953. doi:10.1038/ncomms10953. |
Translational Inhibition of CTX-M Extended Spectrum β-Lactamase in Clinical Strains of Escherichia coli by Synthetic Antisense Oligonucleotides Partially Restores Sensitivity to Cefotaxime
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Front Microbiol. 2016 Mar 24;7:373. eCollection 2016 Epub:
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Synthetic antisense oligomers are DNA mimics that can specifically inhibit gene expression at the translational level by... Delivery Method:
peptide-linked Organism or Cell Type:
Escherichia coli Citation Extract: Readman JB, Dickson G, Coldham NG. Translational Inhibition of CTX-M Extended Spectrum β-Lactamase in Clinical Strains of Escherichia coli by Synthetic Antisense Oligonucleotides Partially Restores Sensitivity to Cefotaxime. Front Microbiol. 2016 Mar 24;7:373. eCollection 2016. |
Roles of mRNA fate modulators Dhh1 and Pat1 in TNRC6-dependent gene silencing recapitulated in yeast
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J Biol Chem. 2015 Mar 27;290(13):8331-47. doi: 10.1074/jbc.M114.615088. Epub 2015 Feb 5 Epub:
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The CCR4-NOT complex, the major deadenylase in eukaryotes, plays crucial roles in gene expression at the levels of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Makino S, Mishima Y, Inoue K, Inada T. Roles of mRNA fate modulators Dhh1 and Pat1 in TNRC6-dependent gene silencing recapitulated in yeast. J Biol Chem. 2015 Mar 27;290(13):8331-47. doi: 10.1074/jbc.M114.615088. Epub 2015 Feb 5. |
Persistence, period and precision of autonomous cellular oscillators from the zebrafish segmentation clock
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Elife. 2016 Feb 13;5. pii: e08438. doi: 10.7554/eLife.08438 Epub:
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In vertebrate development, the sequential and rhythmic segmentation of the body axis is regulated by a "segmentation clock... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Webb AB, Lengyel IM, Jörg DJ, Valentin G, Jülicher F, Morelli LG, Oates AC. Persistence, period and precision of autonomous cellular oscillators from the zebrafish segmentation clock. Elife. 2016 Feb 13;5. pii: e08438. doi: 10.7554/eLife.08438. |
ATR promotes cilia signalling: links to developmental impacts
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Citation:
Hum Mol Genet. 2016 Apr 15;25(8):1574-87. doi: 10.1093/hmg/ddw034. Epub 2016 Feb 11 Epub:
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Mutations in ATR (ataxia telangiectasia and RAD3-related) cause Seckel syndrome (ATR-SS), a microcephalic primordial dwarfism... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Stiff T, Casar Tena T, O'Driscoll M, Jeggo PA, Philipp M. ATR promotes cilia signalling: links to developmental impacts. Hum Mol Genet. 2016 Apr 15;25(8):1574-87. doi: 10.1093/hmg/ddw034. Epub 2016 Feb 11. |
The Zebrafish Equivalent of Alzheimer's Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress
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Citation:
J Alzheimers Dis. 2016 Mar 31. [Epub ahead of print] Epub:
Yes Abstract:
Dominant mutations in the PRESENILIN genes PSEN1 and PSEN2 cause familial Alzheimer's disease (fAD) that usually shows... Organism or Cell Type:
zebrafish Citation Extract: Ebrahimie E, Moussavi-Nik SH, Newman M, Van Der Hoek M, Lardelli M. The Zebrafish Equivalent of Alzheimer's Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress. J Alzheimers Dis. 2016 Mar 31. [Epub ahead of print]. |