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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway
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Citation:
J Biomed Sci. 2016 Aug 2;23(1):59. doi: 10.1186/s12929-016-0277-9 Epub:
Not Epub Abstract:
BACKGROUND: Development of neural and vascular systems displays astonishing similarities among vertebrates. This parallelism is... Organism or Cell Type:
zebrafish Citation Extract: Liu LY, Lin MH, Lai ZY, Jiang JP, Huang YC, Jao LE, Chuang YJ. Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway. J Biomed Sci. 2016 Aug 2;23(1):59. doi: 10.1186/s12929-016-0277-9. |
An amphipathic trans-acting phosphorothioate DNA element delivers uncharged PNA and PMO nucleic acid sequences in mammalian cells
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Citation:
Curr Protoc Nucleic Acid Chem. 2016;64:4.69.1-4.69.22. Epub 2016 Mar 1 Epub:
Not Epub Abstract:
An innovative approach to the delivery of uncharged peptide nucleic acids (PNAs) and phosphorodiamidate morpholino (PMO)... Organism or Cell Type:
cell culture: HeLa pLuc705 Citation Extract: Jain HV, Beaucage SL. An amphipathic trans-acting phosphorothioate DNA element delivers uncharged PNA and PMO nucleic acid sequences in mammalian cells. Curr Protoc Nucleic Acid Chem. 2016;64:4.69.1-4.69.22. Epub 2016 Mar 1. |
[OP.4D.01] Functional Analysis of Tmem63c in Zebrafish Reveals Its Role as a Novel Candidate for Albuminuria and Chronic Kidney Disease
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Citation:
J Hypertens. 2016 Sep;34 Suppl 2:e51. doi: 10.1097/01.hjh.0000491467.44896.76 Epub:
Not Epub Abstract:
OBJECTIVE: The Munich Wistar Frömter (MWF) rat represents a rat model for chronic kidney disease (CKD) with the development of... Organism or Cell Type:
zebrafish Citation Extract: Kreutz R, Schulz A, Meyer AM, Lorenzen T, Stoll M, Panakova D. [OP.4D.01] Functional Analysis of Tmem63c in Zebrafish Reveals Its Role as a Novel Candidate for Albuminuria and Chronic Kidney Disease. J Hypertens. 2016 Sep;34 Suppl 2:e51. doi: 10.1097/01.hjh.0000491467.44896.76. |
Fragile X mental retardation protein knockdown in the developing Xenopus tadpole optic tectum results in enhanced feedforward inhibition and behavioral deficits
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Citation:
Neural Dev. 2016 Aug 8;11(1):14. doi: 10.1186/s13064-016-0069-7 Epub:
Not Epub Abstract:
BACKGROUND: Fragile X Syndrome is the leading monogenetic cause of autism and most common form of intellectual disability.... Delivery Method:
brain injection then electroporation Organism or Cell Type:
Xenopus laevis Citation Extract: Truszkowski TL, James EJ, Hasan M, Wishard TJ, Liu Z, Pratt KG, Cline HT, Aizenman CD. Fragile X mental retardation protein knockdown in the developing Xenopus tadpole optic tectum results in enhanced feedforward inhibition and behavioral deficits. Neural Dev. 2016 Aug 8;11(1):14. doi: 10.1186/s13064-016-0069-7. |
Fis1 depletion in osteoarthritis impairs chondrocyte survival and peroxisomal and lysosomal function
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Citation:
J Mol Med (Berl). 2016 Aug 6. [Epub ahead of print] Epub:
Yes Abstract:
Cumulative evidence suggests the importance of organelle homeostasis in regulating metabolic functions in response to various... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kim D, Song J, Kang Y, Park S, Kim YI, Kwak S, Lim D, Park R, Chun CH, Choe SK, Jin EJ. Fis1 depletion in osteoarthritis impairs chondrocyte survival and peroxisomal and lysosomal function. J Mol Med (Berl). 2016 Aug 6. [Epub ahead of print]. |
Sec16 alternative splicing dynamically controls COPII transport efficiency
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Citation:
Nat Commun. 2016 Aug 5;7:12347. doi: 10.1038/ncomms12347 Epub:
Not Epub Abstract:
The transport of secretory proteins from the endoplasmic reticulum (ER) to the Golgi depends on COPII-coated vesicles. While... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: Hek293 and HeLa and human peripheral blood mononuclear cells (PBMCs) enriched for T cells Citation Extract: Wilhelmi I, Kanski R, Neumann A, Herdt O, Hoff F, Jacob R, Preußner M, Heyd F. Sec16 alternative splicing dynamically controls COPII transport efficiency. Nat Commun. 2016 Aug 5;7:12347. doi: 10.1038/ncomms12347. |
Poly(ester amine) Composed of Polyethylenimine and Pluronic Enhance Delivery of Antisense Oligonucleotides In Vitro and in Dystrophic mdx Mice
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Citation:
Mol Ther Nucleic Acids. 2016 Aug 2;5(8):e341. doi: 10.1038/mtna.2016.51 Epub:
Not Epub Abstract:
A series of poly(esteramine)s (PEAs) constructed from low molecular weight polyethyleneimine (LPEI) and Pluronic were evaluated... Delivery Method:
Endo-Porter, Polyethylenimine and Pluronic (PEAs) Organism or Cell Type:
cell culture: C2C12E50, mdx mice Citation Extract: Wang M, Wu B, Tucker JD, Bollinger LE, Lu P, Lu Q. Poly(ester amine) Composed of Polyethylenimine and Pluronic Enhance Delivery of Antisense Oligonucleotides In Vitro and in Dystrophic mdx Mice. Mol Ther Nucleic Acids. 2016 Aug 2;5(8):e341. doi: 10.1038/mtna.2016.51. |
Recursive splicing in long vertebrate genes
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Citation:
Nature. 2015 May 21;521(7552):371-5. doi:10.1038/nature14466 Epub:
Not Epub Abstract:
It is generally believed that splicing removes introns as single units from precursor messenger RNA transcripts. However, some... Delivery Method:
Endo-porter, microinjection Organism or Cell Type:
SH-SY5Y cells, zebrafish Citation Extract: Sibley CR, Emmett W, Blazquez L, Faro A, Haberman N, Briese M, Trabzuni D, Ryten M, Weale ME, Hardy J, Modic M, Curk T, Wilson SW, Plagnol V, Ule J. Recursive splicing in long vertebrate genes. Nature. 2015 May 21;521(7552):371-5. doi:10.1038/nature14466. |
GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1
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Citation:
Biochemical J. 2016;[Epub ahead of print] doi:10.1042/BCJ20160558 Epub:
Yes Abstract:
Proper hematopoietic cell fate decisions require coordinated functions of transcription factors, their associated co-regulators... Organism or Cell Type:
zebrafish Citation Extract: Velinder M, Singer J, Bareyan D, Meznarich J, Tracy CM, Fulcher JM, McClellan D, Lucente H, Franklin S, Sharma S, Engel ME. GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1. Biochemical J. 2016;[Epub ahead of print] doi:10.1042/BCJ20160558. |
The endoderm indirectly influences morphogenetic movements of the zebrafish head kidney through the posterior cardinal vein and VegfC
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Citation:
Sci Rep. 2016 Aug 1;6:30677. doi: 10.1038/srep30677 Epub:
Not Epub Abstract:
Integration of blood vessels and organ primordia determines organ shape and function. The head kidney in the zebrafish... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chou CW, Hsu HC, You MS, Lin J, Liu YW. The endoderm indirectly influences morphogenetic movements of the zebrafish head kidney through the posterior cardinal vein and VegfC. Sci Rep. 2016 Aug 1;6:30677. doi: 10.1038/srep30677. |