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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry

Authors:
Takeuchi JK, Lickert H, Bisgrove BW, Sun X, Yamamoto M, Chawengsaksophak K, Hamada H, Yost HJ, Rossant J, Bruneau BG
Citation:
Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):846-51. Epub 2007 Jan 8
Epub:
Not Epub
Abstract:
Notch-mediated induction of Nodal at the vertebrate node is a critical step in initiating left-right (LR) asymmetry. In mice...
Link:
http://www.pnas.org/content/104/3/846.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Takeuchi JK, Lickert H, Bisgrove BW, Sun X, Yamamoto M, Chawengsaksophak K, Hamada H, Yost HJ, Rossant J, Bruneau BG. Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry. Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):846-51. Epub 2007 Jan 8.

cMyb acts in parallel and cooperatively with Cebp1 to regulate neutrophil maturation in zebrafish

Authors:
Jin H, Huang Z, Chi Y, Wu M, Zhou R, Zhao L, Xu J, Zhen F, Lan Y, Li L, Zhang W, Wen Z, Zhang Y
Citation:
Blood. 2016 Jun 6. pii: blood-2015-12-686147. [Epub ahead of print]
Epub:
Yes
Abstract:
Neutrophils are the key effectors for generating innate immunity in response to pathogenic infection and tissue injury in...
Link:
http://www.bloodjournal.org/content/128/3/415
Organism or Cell Type:
zebrafish
Citation Extract:
Jin H, Huang Z, Chi Y, Wu M, Zhou R, Zhao L, Xu J, Zhen F, Lan Y, Li L, Zhang W, Wen Z, Zhang Y. cMyb acts in parallel and cooperatively with Cebp1 to regulate neutrophil maturation in zebrafish. Blood. 2016 Jun 6. pii: blood-2015-12-686147. [Epub ahead of print].

Cholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling

Authors:
Mathews ES, Appel B
Citation:
J Neurosci. 2016;36(29):7628-39. doi:10.1523/JNEUROSCI.0726-16.2016
Epub:
Not Epub
Abstract:
Myelin, which ensheaths and insulates axons, is a specialized membrane highly enriched with cholesterol. During myelin...
Link:
http://www.jneurosci.org/content/36/29/7628.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mathews ES, Appel B. Cholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling. J Neurosci. 2016;36(29):7628-39. doi:10.1523/JNEUROSCI.0726-16.2016.

RNA- binding protein Stau2 is important for spindle integrity and meiosis progression in mouse oocytes

Authors:
Cao Y, Du J, Chen D, Wang Q, Zhang N, Liu X, Liu X, Weng J, Liang Y, Ma W
Citation:
Cell Cycle. 2016 Jul 19:0. [Epub ahead of print]
Epub:
Yes
Abstract:
Staufen2 (Stau2) is a double-stranded RNA-binding protein involved in cell fate decision by regulating mRNA transport, mRNA...
Link:
http://www.tandfonline.com/doi/abs/10.1080/15384101.2016.1208869
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Cao Y, Du J, Chen D, Wang Q, Zhang N, Liu X, Liu X, Weng J, Liang Y, Ma W. RNA- binding protein Stau2 is important for spindle integrity and meiosis progression in mouse oocytes. Cell Cycle. 2016 Jul 19:0. [Epub ahead of print].

A gene trap transposon eliminates haematopoietic expression of zebrafish Gfi1aa, but does not interfere with haematopoiesis

Authors:
Thambyrajah R, Ucanok D, Jalali M, Hough Y, Wilkinson RN, McMahon K, Moore C, Gering M
Citation:
Dev Biol. 2016 Jul 15. pii: S0012-1606(16)30160-9. doi: 10.1016/j.ydbio.2016.07.010. [Epub ahead of print]
Epub:
Yes
Abstract:
A transposon-mediated gene trap screen identified the zebrafish line qmc551 that expresses a GFP reporter in primitive...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616301609
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thambyrajah R, Ucanok D, Jalali M, Hough Y, Wilkinson RN, McMahon K, Moore C, Gering M. A gene trap transposon eliminates haematopoietic expression of zebrafish Gfi1aa, but does not interfere with haematopoiesis. Dev Biol. 2016 Jul 15. pii: S0012-1606(16)30160-9. doi: 10.1016/j.ydbio.2016.07.010. [Epub ahead of print].

Exon 53 skipping of the dystrophin gene in patients with Duchenne muscular dystrophy by systemic administration of NS-065/NCNP-01: A phase 1, dose escalation, first-in-human study

Authors:
Komaki H, Nagata T, Saito T, Masuda S, Takeshita E, Tachimori H, Sasaki M, Takeda S
Citation:
Neuromusc Disord. 2015;26(2)S261-2 doi:10.1016/j.nmd.2015.06.276
Epub:
Not Epub
Abstract:
Antisense oligonucleotide-induced exon skipping, which is being studied for the treatment of Duchenne muscular dystrophy (DMD...
Link:
http://www.nmd-journal.com/article/S0960-8966(15)00457-5/abstract
Organism or Cell Type:
human
Citation Extract:
Komaki H, Nagata T, Saito T, Masuda S, Takeshita E, Tachimori H, Sasaki M, Takeda S. Exon 53 skipping of the dystrophin gene in patients with Duchenne muscular dystrophy by systemic administration of NS-065/NCNP-01: A phase 1, dose escalation, first-in-human study. Neuromusc Disord. 2015;26(2)S261-2 doi:10.1016/j.nmd.2015.06.276.

A transcription factor network controls cell migration and fate decisions in the developing zebrafish pineal complex

Authors:
Khuansuwan S, Clanton JA, Dean BJ, Patton JG, Gamse JT
Citation:
Development. 2016 Jun 17. pii: dev.131680. [Epub ahead of print]
Epub:
Yes
Abstract:
The zebrafish pineal complex consists of four cell types (rod and cone photoreceptors, projection neurons, and parapineal...
Link:
http://dev.biologists.org/content/143/14/2641.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Khuansuwan S, Clanton JA, Dean BJ, Patton JG, Gamse JT. A transcription factor network controls cell migration and fate decisions in the developing zebrafish pineal complex. Development. 2016 Jun 17. pii: dev.131680. [Epub ahead of print].

Alk1 controls arterial endothelial cell migration in lumenized vessels

Authors:
Rochon ER, Menon PG, Roman BL
Citation:
Development. 2016 Jun 10. pii: dev.135392. [Epub ahead of print]
Epub:
Yes
Abstract:
Heterozygous loss of the arterial-specific TGF-β type I receptor, activin receptor-like kinase 1 (ALK1), causes hereditary...
Link:
http://dev.biologists.org/content/143/14/2593.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rochon ER, Menon PG, Roman BL. Alk1 controls arterial endothelial cell migration in lumenized vessels. Development. 2016 Jun 10. pii: dev.135392. [Epub ahead of print].

The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling

Authors:
Kwan W, Cortes M, Frost I, Esain V, Theodore LN, Liu SY, Budrow N, Goessling W, North TE.
Citation:
Cell Stem Cell. 2016;[Epub] doi:10.1016/j.stem.2016.06.004
Epub:
Yes
Abstract:
Hematopoietic stem and progenitor cell (HSPC) specification is regulated by numerous defined factors acting locally within the...
Link:
http://www.cell.com/cell-stem-cell/abstract/S1934-5909(16)30154-0
Citation Extract:
Kwan W, Cortes M, Frost I, Esain V, Theodore LN, Liu SY, Budrow N, Goessling W, North TE.. The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling. Cell Stem Cell. 2016;[Epub] doi:10.1016/j.stem.2016.06.004.

New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections

Authors:
McPhillie M, Zhou Y, El Bissati K, Dubey J, Lorenzi H, Capper M, Lukens AK, Hickman M, Muench S, Verma SK, Weber CR, Wheeler K, Gordon J, Sanders J, Moulton H, Wang K, Kim TK, He Y, Santos T, Woods S, Lee P, Donkin D, Kim E, Fraczek L, Lykins J, Esaa F, Alibana-Clouser F, Dovgin S, Weiss L, Brasseur G, Wirth D, Kent M, Hood L, Meunieur B, Roberts CW, Hasnain SS, Antonyuk SV, Fishwick C, McLeod R
Citation:
Sci Rep. 2016 Jul 14;6:29179. doi: 10.1038/srep29179
Epub:
Not Epub
Abstract:
Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifetimes, can progressively...
Link:
http://www.nature.com/articles/srep29179
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: Toxoplasma gondii, RH-YFP tachyzoites and EGS^S14 bradyzoites
Citation Extract:
McPhillie M, Zhou Y, El Bissati K, Dubey J, Lorenzi H, Capper M, Lukens AK, Hickman M, Muench S, Verma SK, Weber CR, Wheeler K, Gordon J, Sanders J, Moulton H, Wang K, Kim TK, He Y, Santos T, Woods S, Lee P, Donkin D, Kim E, Fraczek L, Lykins J, Esaa F, Alibana-Clouser F, Dovgin S, Weiss L, Brasseur G, Wirth D, Kent M, Hood L, Meunieur B, Roberts CW, Hasnain SS, Antonyuk SV, Fishwick C, McLeod R. New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections. Sci Rep. 2016 Jul 14;6:29179. doi: 10.1038/srep29179.

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