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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs

Authors:
Goodale BC, La Du J, Tilton SC, Sullivan CM, Bisson WH, Waters KM, Tanguay RL
Citation:
Toxicol Sci. 2015 Oct;147(2):397-411. doi: 10.1093/toxsci/kfv139. Epub 2015 Jul 3
Epub:
Not Epub
Abstract:
Polycyclic aromatic hydrocarbons (PAHs) are priority environmental contaminants that exhibit mutagenic, carcinogenic,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Goodale BC, La Du J, Tilton SC, Sullivan CM, Bisson WH, Waters KM, Tanguay RL. Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs. Toxicol Sci. 2015 Oct;147(2):397-411. doi: 10.1093/toxsci/kfv139. Epub 2015 Jul 3.

Active DNA demethylation at enhancers during the vertebrate phylotypic period

Authors:
Bogdanović O, Smits AH, de la Calle Mustienes E, Tena JJ, Ford E, Williams R, Senanayake U, Schultz MD, Hontelez S, van Kruijsbergen I, Rayon T, Gnerlich F, Carell T, Veenstra GJ, Manzanares M, Sauka-Spengler T, Ecker JR, Vermeulen M, Gómez-Skarmeta JL, Lister R
Citation:
Nat Genet. 2016 Feb 29. doi: 10.1038/ng.3522. [Epub ahead of print]
Epub:
Yes
Abstract:
The vertebrate body plan and organs are shaped during a conserved embryonic phase called the phylotypic stage. However, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bogdanović O, Smits AH, de la Calle Mustienes E, Tena JJ, Ford E, Williams R, Senanayake U, Schultz MD, Hontelez S, van Kruijsbergen I, Rayon T, Gnerlich F, Carell T, Veenstra GJ, Manzanares M, Sauka-Spengler T, Ecker JR, Vermeulen M, Gómez-Skarmeta JL, Lister R. Active DNA demethylation at enhancers during the vertebrate phylotypic period. Nat Genet. 2016 Feb 29. doi: 10.1038/ng.3522. [Epub ahead of print].

Slow Muscle Precursors Lay Down a Collagen XV Matrix Fingerprint to Guide Motor Axon Navigation

Authors:
Guillon E, Bretaud S, Ruggiero F
Citation:
J Neurosci. 2016;36(9):2663-76. doi:10.1523/JNEUROSCI.2847-15.2016
Epub:
Not Epub
Abstract:
The extracellular matrix (ECM) provides local positional information to guide motoneuron axons toward their muscle target....
Organism or Cell Type:
zebrafish
Citation Extract:
Guillon E, Bretaud S, Ruggiero F. Slow Muscle Precursors Lay Down a Collagen XV Matrix Fingerprint to Guide Motor Axon Navigation. J Neurosci. 2016;36(9):2663-76. doi:10.1523/JNEUROSCI.2847-15.2016.

MARCKS-like protein is an initiating molecule in axolotl appendage regeneration

Authors:
Sugiura T, Wang H, Barsacchi R, Simon A, Tanaka EM
Citation:
Nature. 2016;[Epub ahead of print] doi:10.1038/nature16974
Epub:
Yes
Abstract:
Identifying key molecules that launch regeneration has been a long-sought goal. Multiple regenerative animals show an initial...
Delivery Method:
electroporation, injection then electroporation
Organism or Cell Type:
cell culture: A1 myoblasts, axolotl
Citation Extract:
Sugiura T, Wang H, Barsacchi R, Simon A, Tanaka EM. MARCKS-like protein is an initiating molecule in axolotl appendage regeneration. Nature. 2016;[Epub ahead of print] doi:10.1038/nature16974.

ES1 is a mitochondrial enlarging factor contributing to form mega-mitochondria in zebrafish cones

Authors:
Masuda T, Wada Y, Kawamura S
Citation:
Sci Rep. 2016 Mar 1;6:22360. doi: 10.1038/srep22360
Epub:
Not Epub
Abstract:
Total mass of mitochondria increases during cell proliferation and differentiation through mitochondrial biogenesis, which...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Masuda T, Wada Y, Kawamura S. ES1 is a mitochondrial enlarging factor contributing to form mega-mitochondria in zebrafish cones. Sci Rep. 2016 Mar 1;6:22360. doi: 10.1038/srep22360.

Assessing Smoothened-mediated Hedgehog signaling in zebrafish

Authors:
Tena TC, Philipp M
Citation:
Methods Cell Biol. 2016;132:147-64. doi: 10.1016/bs.mcb.2015.10.001. Epub 2015 Dec 24
Epub:
Not Epub
Abstract:
Smoothened belongs to the class of atypical G protein-coupled receptors and serves as the transducing molecule in Hedgehog (Hh...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tena TC, Philipp M. Assessing Smoothened-mediated Hedgehog signaling in zebrafish. Methods Cell Biol. 2016;132:147-64. doi: 10.1016/bs.mcb.2015.10.001. Epub 2015 Dec 24.

Knockdown of zebrafish YY1a can downregulate the phosphatidylserine (PS) receptor expression, leading to induce the abnormal brain and heart development

Authors:
Shiu WL, Huang KR, Hung JC, Wu JL, Hong JR
Citation:
J Biomed Sci. 2016 Feb 29;23(1):31. doi: 10.1186/s12929-016-0248-1
Epub:
Not Epub
Abstract:
BACKGROUND: Yin Yang 1 (YY1) is a ubiquitously expressed GLI-Kruppel zinc finger-containing transcriptional regulator. YY1...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shiu WL, Huang KR, Hung JC, Wu JL, Hong JR. Knockdown of zebrafish YY1a can downregulate the phosphatidylserine (PS) receptor expression, leading to induce the abnormal brain and heart development. J Biomed Sci. 2016 Feb 29;23(1):31. doi: 10.1186/s12929-016-0248-1.

xCyp26c Induced by Inhibition of BMP Signaling Is Involved in Anterior-Posterior Neural Patterning of Xenopus laevis

Authors:
Yu SB, Umair Z, Kumar S, Lee U, Lee SH, Kim JI, Kim S, Park JB, Lee JY, Kim J
Citation:
Mol Cells. 2016 Feb 29. doi: 10.14348/molcells.2016.0006. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Vertebrate neurogenesis requires inhibition of endogenous bone morphogenetic protein (BMP) signals in the ectoderm. Blocking of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yu SB, Umair Z, Kumar S, Lee U, Lee SH, Kim JI, Kim S, Park JB, Lee JY, Kim J. xCyp26c Induced by Inhibition of BMP Signaling Is Involved in Anterior-Posterior Neural Patterning of Xenopus laevis. Mol Cells. 2016 Feb 29. doi: 10.14348/molcells.2016.0006. [Epub ahead of print].

DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia

Authors:
Li Y, Yagi H, Onuoha EO, Damerla RR, Francis R, Furutani Y, Tariq M, King SM, Hendricks G, Cui C, Saydmohammed M, Lee DM, Zahid M, Sami I, Leatherbury L, Pazour GJ, Ware SM, Nakanishi T, Goldmuntz E, Tsang M, Lo CW
Citation:
PLoS Genet. 2016 Feb 26;12(2):e1005821. doi: 10.1371/journal.pgen.1005821. eCollection 2016 Feb
Epub:
Not Epub
Abstract:
Heterotaxy, a birth defect involving left-right patterning defects, and primary ciliary dyskinesia (PCD), a sinopulmonary...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li Y, Yagi H, Onuoha EO, Damerla RR, Francis R, Furutani Y, Tariq M, King SM, Hendricks G, Cui C, Saydmohammed M, Lee DM, Zahid M, Sami I, Leatherbury L, Pazour GJ, Ware SM, Nakanishi T, Goldmuntz E, Tsang M, Lo CW. DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia. PLoS Genet. 2016 Feb 26;12(2):e1005821. doi: 10.1371/journal.pgen.1005821. eCollection 2016 Feb.

Biological outcome and mapping of total factor cascades in response to HIF induction during regenerative angiogenesis

Authors:
Khatib A-M, Lahlil R, Hagedorn M, Delomenie C, Christophe O, Denis C, Siegfried G
Citation:
Oncotarget. 2016;[Epub ahead of print] doi:10.18632/oncotarget.7728
Epub:
Yes
Abstract:
Hypoxia Inducible Factor (HIF) is the main transcription factor that mediates cell response to hypoxia. Howeverthe complex...
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Khatib A-M, Lahlil R, Hagedorn M, Delomenie C, Christophe O, Denis C, Siegfried G. Biological outcome and mapping of total factor cascades in response to HIF induction during regenerative angiogenesis. Oncotarget. 2016;[Epub ahead of print] doi:10.18632/oncotarget.7728.

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