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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Integration of Multiplexed Microfluidic Electrokinetic Concentrators with a Morpholino Microarray via Reversible Surface Bonding for Enhanced DNA Hybridization

Authors:
Martins D, Wei X, Levicky R, Song Y-AR
Citation:
Anal Chem. 2016;[Epub ahead of print] doi:10.1021/acs.analchem.5b03875
Epub:
Not Epub
Abstract:
We describe a microfluidic concentration device to accelerate the surface hybridization reaction between DNA and morpholinos (...
Link:
http://pubs.acs.org/doi/abs/10.1021/acs.analchem.5b03875
Citation Extract:
Martins D, Wei X, Levicky R, Song Y-AR. Integration of Multiplexed Microfluidic Electrokinetic Concentrators with a Morpholino Microarray via Reversible Surface Bonding for Enhanced DNA Hybridization. Anal Chem. 2016;[Epub ahead of print] doi:10.1021/acs.analchem.5b03875.

Zygotic LvBMP5-8 is required for skeletal patterning and for left-right but not dorsal-ventral specification in the sea urchin embryo

Authors:
Piacentino ML, Chung O, Ramachandran J, Zuch DT, Yu J, Conaway EA, Reyna AE, Bradham CA
Citation:
Dev Biol. 2016 Feb 20. pii: S0012-1606(15)30209-8. doi: 10.1016/j.ydbio.2016.02.015. [Epub ahead of print]
Epub:
Yes
Abstract:
Skeletal patterning in the sea urchin embryo requires coordinated signaling between the pattern-dictating ectoderm and the...
Link:
http://www.sciencedirect.com/science/journal/aip/00121606
Organism or Cell Type:
sea urchin
Citation Extract:
Piacentino ML, Chung O, Ramachandran J, Zuch DT, Yu J, Conaway EA, Reyna AE, Bradham CA. Zygotic LvBMP5-8 is required for skeletal patterning and for left-right but not dorsal-ventral specification in the sea urchin embryo. Dev Biol. 2016 Feb 20. pii: S0012-1606(15)30209-8. doi: 10.1016/j.ydbio.2016.02.015. [Epub ahead of print].

Mutations in Subunits of the Activating Signal Cointegrator 1 Complex Are Associated with Prenatal Spinal Muscular Atrophy and Congenital Bone Fractures

Authors:
Knierim E, Hirata H, Wolf NI, Morales-Gonzalez S, Schottmann G, Tanaka Y, Rudnik-Schöneborn S, Orgeur M, Zerres K, Vogt S, van Riesen A, Gill E, Seifert F, Zwirner A, Kirschner J, Goebel HH, Hübner C, Stricker S, Meierhofer D, Stenzel W, Schuelke M
Citation:
Am J Hum Genet. 2016;[Epub ahead of print] doi:10.1016/j.ajhg.2016.01.006
Epub:
Yes
Abstract:
Transcriptional signal cointegrators associate with transcription factors or nuclear receptors and coregulate tissue-specific...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297%2816%2900012-4
Organism or Cell Type:
zebrafish
Citation Extract:
Knierim E, Hirata H, Wolf NI, Morales-Gonzalez S, Schottmann G, Tanaka Y, Rudnik-Schöneborn S, Orgeur M, Zerres K, Vogt S, van Riesen A, Gill E, Seifert F, Zwirner A, Kirschner J, Goebel HH, Hübner C, Stricker S, Meierhofer D, Stenzel W, Schuelke M. Mutations in Subunits of the Activating Signal Cointegrator 1 Complex Are Associated with Prenatal Spinal Muscular Atrophy and Congenital Bone Fractures. Am J Hum Genet. 2016;[Epub ahead of print] doi:10.1016/j.ajhg.2016.01.006.

Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis

Authors:
Raman M, Sergeev M, Garnaas M, Lydeard JR, Huttlin EL, Goessling W, Shah JV, Harper JW
Citation:
Nat Cell Biol. 2015 Oct;17(10):1356-69. doi: 10.1038/ncb3238. Epub 2015 Sep 21
Epub:
Not Epub
Abstract:
The AAA-ATPase VCP (also known as p97 or CDC48) uses ATP hydrolysis to 'segregate' ubiquitylated proteins from their...
Link:
http://www.nature.com/ncb/journal/v17/n10/full/ncb3238.html
Organism or Cell Type:
zebrafish
Citation Extract:
Raman M, Sergeev M, Garnaas M, Lydeard JR, Huttlin EL, Goessling W, Shah JV, Harper JW. Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis. Nat Cell Biol. 2015 Oct;17(10):1356-69. doi: 10.1038/ncb3238. Epub 2015 Sep 21.

Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress

Authors:
Rissone A, Weinacht KG, la Marca G, Bishop K, Giocaliere E, Jagadeesh J, Felgentreff K, Dobbs K, Al-Herz W, Jones M, Chandrasekharappa S, Kirby M, Wincovitch S, Simon KL, Itan Y, DeVine A, Schlaeger T, Schambach A, Sood R, Notarangelo LD, Candotti F
Citation:
J Exp Med. 2015 Jul 27;212(8):1185-202. doi: 10.1084/jem.20141286. Epub 2015 Jul 6
Epub:
Not Epub
Abstract:
Adenylate kinases (AKs) are phosphotransferases that regulate the cellular adenine nucleotide composition and play a critical...
Link:
http://jem.rupress.org/content/212/8/1185.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rissone A, Weinacht KG, la Marca G, Bishop K, Giocaliere E, Jagadeesh J, Felgentreff K, Dobbs K, Al-Herz W, Jones M, Chandrasekharappa S, Kirby M, Wincovitch S, Simon KL, Itan Y, DeVine A, Schlaeger T, Schambach A, Sood R, Notarangelo LD, Candotti F. Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress. J Exp Med. 2015 Jul 27;212(8):1185-202. doi: 10.1084/jem.20141286. Epub 2015 Jul 6.

DNA methylation analysis of Homeobox genes implicates HOXB7 hypomethylation as risk factor for neural tube defects

Authors:
Rochtus A, Izzi B, Vangeel E, Louwette S, Wittevrongel C, Lambrechts D, Moreau Y, Winand R, Verpoorten C, Jansen K, Van Geet C, Freson K
Citation:
Epigenetics. 2015;10(1):92-101. doi: 10.1080/15592294.2014.998531. Epub 2015 Jan 29
Epub:
Not Epub
Abstract:
Neural tube defects (NTDs) are common birth defects of complex etiology. Though family- and population-based studies have...
Link:
http://www.tandfonline.com/doi/full/10.1080/15592294.2014.998531
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rochtus A, Izzi B, Vangeel E, Louwette S, Wittevrongel C, Lambrechts D, Moreau Y, Winand R, Verpoorten C, Jansen K, Van Geet C, Freson K. DNA methylation analysis of Homeobox genes implicates HOXB7 hypomethylation as risk factor for neural tube defects. Epigenetics. 2015;10(1):92-101. doi: 10.1080/15592294.2014.998531. Epub 2015 Jan 29.

Analysis of mucolipidosis II/III GNPTAB missense mutations identifies domains of UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase involved in catalytic function and lysosomal enzyme recognition

Authors:
Qian Y, van Meel E, Flanagan-Steet H, Yox A, Steet R, Kornfeld S
Citation:
J Biol Chem. 2015 Jan 30;290(5):3045-56. doi: 10.1074/jbc.M114.612507. Epub 2014 Dec 11
Epub:
Not Epub
Abstract:
UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase tags newly synthesized lysosomal enzymes with mannose 6-phosphate...
Link:
http://www.jbc.org/content/290/5/3045.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Qian Y, van Meel E, Flanagan-Steet H, Yox A, Steet R, Kornfeld S. Analysis of mucolipidosis II/III GNPTAB missense mutations identifies domains of UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase involved in catalytic function and lysosomal enzyme recognition. J Biol Chem. 2015 Jan 30;290(5):3045-56. doi: 10.1074/jbc.M114.612507. Epub 2014 Dec 11.

Conservation of the STING-Mediated Cytosolic DNA Sensing Pathway in Zebrafish

Authors:
Ge R, Zhou Y, Peng R, Wang R, Li M, Zhang Y, Zheng C, Wang C
Citation:
J Virol. 2015 Aug;89(15):7696-706. doi: 10.1128/JVI.01049-15. Epub 2015 May 13
Epub:
Not Epub
Abstract:
Zebrafish (Danio rerio) is a unique potential model animal for dissecting innate immune signaling. Here we demonstrate that...
Link:
http://jvi.asm.org/content/89/15/7696.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ge R, Zhou Y, Peng R, Wang R, Li M, Zhang Y, Zheng C, Wang C. Conservation of the STING-Mediated Cytosolic DNA Sensing Pathway in Zebrafish. J Virol. 2015 Aug;89(15):7696-706. doi: 10.1128/JVI.01049-15. Epub 2015 May 13.

Animal model of Sar1b deficiency presents lipid absorption deficits similar to Anderson disease

Authors:
Levic DS, Minkel JR, Wang WD, Rybski WM, Melville DB, Knapik EW
Citation:
J Mol Med (Berl). 2015 Feb;93(2):165-76. doi: 10.1007/s00109-014-1247-x. Epub 2015 Jan 7
Epub:
Not Epub
Abstract:
Anderson disease (ANDD) or chylomicron retention disease (CMRD) is a rare, hereditary lipid malabsorption syndrome associated...
Link:
http://link.springer.com/article/10.1007%2Fs00109-014-1247-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Levic DS, Minkel JR, Wang WD, Rybski WM, Melville DB, Knapik EW. Animal model of Sar1b deficiency presents lipid absorption deficits similar to Anderson disease. J Mol Med (Berl). 2015 Feb;93(2):165-76. doi: 10.1007/s00109-014-1247-x. Epub 2015 Jan 7.

FAT1 mutations cause a glomerulotubular nephropathy

Authors:
Gee HY, Sadowski CE, Aggarwal PK, Porath JD, Yakulov TA, Schueler M, Lovric S, Ashraf S, Braun DA, Halbritter J, Fang H, Airik R, Vega-Warner V, Cho KJ, Chan TA, Morris LGT, ffrench-Constant C, Allen N, McNeill H, Büscher R, Kyrieleis H, Wallot M, Gaspert A, Kistler T, Milford DV, Saleem MA, Keng WT, Alexander SI, Valentini RP, Licht C, Teh JC, Bogdanovic R, Koziell A, Bierzynska A, Soliman NA, Otto EA, Lifton RP, Holzman LB, Sibinga NES, Walz G, Tufro A, Hildebrandt F
Citation:
Nat Comm. 2016;7:10822 doi:10.1038/ncomms10822
Epub:
Not Epub
Abstract:
Steroid-resistant nephrotic syndrome (SRNS) causes 15% of chronic kidney disease (CKD). Here we show that recessive mutations...
Link:
http://www.nature.com/ncomms/2016/160224/ncomms10822/full/ncomms10822.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gee HY, Sadowski CE, Aggarwal PK, Porath JD, Yakulov TA, Schueler M, Lovric S, Ashraf S, Braun DA, Halbritter J, Fang H, Airik R, Vega-Warner V, Cho KJ, Chan TA, Morris LGT, ffrench-Constant C, Allen N, McNeill H, Büscher R, Kyrieleis H, Wallot M, Gaspert A, Kistler T, Milford DV, Saleem MA, Keng WT, Alexander SI, Valentini RP, Licht C, Teh JC, Bogdanovic R, Koziell A, Bierzynska A, Soliman NA, Otto EA, Lifton RP, Holzman LB, Sibinga NES, Walz G, Tufro A, Hildebrandt F. FAT1 mutations cause a glomerulotubular nephropathy. Nat Comm. 2016;7:10822 doi:10.1038/ncomms10822.

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