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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis

Authors:
Villa M, Crotta S, Dingwell KS, Hirst EM, Gialitakis M, Ahlfors H, Smith JC, Stockinger B, Wack A
Citation:
Nat Commun. 2016 Aug 24;7:12652. doi: 10.1038/ncomms12652
Epub:
Not Epub
Abstract:
Epithelia function as barriers against environmental insults and express the transcription factor aryl hydrocarbon receptor (...
Link:
http://www.nature.com/ncomms/2016/160824/ncomms12652/full/ncomms12652.html
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Villa M, Crotta S, Dingwell KS, Hirst EM, Gialitakis M, Ahlfors H, Smith JC, Stockinger B, Wack A. The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis. Nat Commun. 2016 Aug 24;7:12652. doi: 10.1038/ncomms12652.

Differential Nanos 2 protein stability results in selective germ cell accumulation in the sea urchin

Authors:
Oulhen N, Wessel GM
Citation:
Dev Biol. 2016 Jul 14. pii: S0012-1606(16)30012-4. doi: 10.1016/j.ydbio.2016.07.007. [Epub ahead of print]
Epub:
Yes
Abstract:
Nanos is a translational regulator required for the survival and maintenance of primordial germ cells. In the sea urchin,...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616300124
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin), Patiria miniata (starfish)
Citation Extract:
Oulhen N, Wessel GM. Differential Nanos 2 protein stability results in selective germ cell accumulation in the sea urchin. Dev Biol. 2016 Jul 14. pii: S0012-1606(16)30012-4. doi: 10.1016/j.ydbio.2016.07.007. [Epub ahead of print].

Hedgehog-dependent E3-ligase Midline1 regulates ubiquitin-mediated proteasomal degradation of Pax6 during visual system development

Authors:
Pfirrmann T, Jandt E, Ranft S, Lokapally A, Neuhaus H, Perron M, Hollemann T
Citation:
Proc Natl Acad Sci U S A. 2016 Aug 23. pii: 201600770. [Epub ahead of print]
Epub:
Yes
Abstract:
Pax6 is a key transcription factor involved in eye, brain, and pancreas development. Although pax6 is expressed in the whole...
Link:
http://www.pnas.org/content/early/2016/08/22/1600770113.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pfirrmann T, Jandt E, Ranft S, Lokapally A, Neuhaus H, Perron M, Hollemann T. Hedgehog-dependent E3-ligase Midline1 regulates ubiquitin-mediated proteasomal degradation of Pax6 during visual system development. Proc Natl Acad Sci U S A. 2016 Aug 23. pii: 201600770. [Epub ahead of print].

Neuromuscular NMDA Receptors Modulate Developmental Synapse Elimination

Authors:
Personius KE, Slusher BS, Udin SB
Citation:
J Neurosci. 2016 Aug 24;36(34):8783-9. doi: 10.1523/JNEUROSCI.1181-16.2016
Epub:
Not Epub
Abstract:
At birth, each mammalian skeletal muscle fiber is innervated by multiple motor neurons, but in a few weeks, all but one of...
Link:
http://www.jneurosci.org/content/36/34/8783.abstract
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Personius KE, Slusher BS, Udin SB. Neuromuscular NMDA Receptors Modulate Developmental Synapse Elimination. J Neurosci. 2016 Aug 24;36(34):8783-9. doi: 10.1523/JNEUROSCI.1181-16.2016.

Manduca Contactin Regulates Amyloid Precursor Protein-Dependent Neuronal Migration

Authors:
Ramaker JM, Swanson TL, Copenhaver PF
Citation:
J Neurosci. 2016 Aug 17;36(33):8757-75. doi: 10.1523/JNEUROSCI.0729-16.2016
Epub:
Not Epub
Abstract:
Amyloid precursor protein (APP) was originally identified as the source of β-amyloid peptides that accumulate in Alzheimer...
Link:
http://www.jneurosci.org/content/36/33/8757.abstract
Organism or Cell Type:
Manduca sexta (hawkmoth)
Citation Extract:
Ramaker JM, Swanson TL, Copenhaver PF. Manduca Contactin Regulates Amyloid Precursor Protein-Dependent Neuronal Migration. J Neurosci. 2016 Aug 17;36(33):8757-75. doi: 10.1523/JNEUROSCI.0729-16.2016.

De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome

Authors:
Kim JH, Shinde DN, Reijnders MR, Hauser NS, Belmonte RL, Wilson GR, Bosch DG, Bubulya PA, Shashi V, Petrovski S, Stone JK, Park EY, Veltman JA, Sinnema M, Stumpel CT, Draaisma JM, Nicolai J; University of Washington Center for Mendelian Genomics, Yntema HG, Lindstrom K, de Vries BB, Jewett T, Santoro SL, Vogt J; Deciphering Developmental Disorders Study, Bachman KK, Seeley AH, Krokosky A, Turner C, Rohena L, Hempel M, Kortüm F, Lessel D, Neu A, Strom TM, <authors removed - database limit> Begtrup A, Funari T, Schoch K, Stegmann AP, Stevens SJ, Zhang DE, Traver D, Yao X, MacArthur DG, Brunner HG, Mancini GM, Myers RM, Owen LB, Lim ST, Stachura DL, Vissers LE, Ahn EE
Citation:
Am J Hum Genet. 2016 Aug 17. pii: S0002-9297(16)30267-1. doi: 10.1016/j.ajhg.2016.06.029. [Epub ahead of print]
Epub:
Yes
Abstract:
The overall understanding of the molecular etiologies of intellectual disability (ID) and developmental delay (DD) is...
Link:
http://www.sciencedirect.com/science/article/pii/S0002929716302671
Organism or Cell Type:
zebrafish
Citation Extract:
Kim JH, Shinde DN, Reijnders MR, Hauser NS, Belmonte RL, Wilson GR, Bosch DG, Bubulya PA, Shashi V, Petrovski S, Stone JK, Park EY, Veltman JA, Sinnema M, Stumpel CT, Draaisma JM, Nicolai J; University of Washington Center for Mendelian Genomics, Yntema HG, Lindstrom K, de Vries BB, Jewett T, Santoro SL, Vogt J; Deciphering Developmental Disorders Study, Bachman KK, Seeley AH, Krokosky A, Turner C, Rohena L, Hempel M, Kortüm F, Lessel D, Neu A, Strom TM, <authors removed - database limit> Begtrup A, Funari T, Schoch K, Stegmann AP, Stevens SJ, Zhang DE, Traver D, Yao X, MacArthur DG, Brunner HG, Mancini GM, Myers RM, Owen LB, Lim ST, Stachura DL, Vissers LE, Ahn EE. De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome. Am J Hum Genet. 2016 Aug 17. pii: S0002-9297(16)30267-1. doi: 10.1016/j.ajhg.2016.06.029. [Epub ahead of print].

Biallelic Variants in UBA5 Reveal that Disruption of the UFM1 Cascade Can Result in Early-Onset Encephalopathy

Authors:
Colin E, Daniel J, Ziegler A, Wakim J, Scrivo A, Haack TB, Khiati S, Denommé AS, Amati-Bonneau P, Charif M, Procaccio V, Reynier P, Aleck KA, Botto LD, Herper CL, Kaiser CS, Nabbout R, N'Guyen S, Mora-Lorca JA, Assmann B, Christ S, Meitinger T, Strom TM, Prokisch H; FREX Consortium, Miranda-Vizuete A, Hoffmann GF, Lenaers G, Bomont P, Liebau E, Bonneau D
Citation:
Am J Hum Genet. 2016 Aug 17. pii: S0002-9297(16)30268-3. doi: 10.1016/j.ajhg.2016.06.030. [Epub ahead of print]
Epub:
Yes
Abstract:
Via whole-exome sequencing, we identified rare autosomal-recessive variants in UBA5 in five children from four unrelated...
Link:
http://www.sciencedirect.com/science/article/pii/S0002929716302683
Organism or Cell Type:
zebrafish
Citation Extract:
Colin E, Daniel J, Ziegler A, Wakim J, Scrivo A, Haack TB, Khiati S, Denommé AS, Amati-Bonneau P, Charif M, Procaccio V, Reynier P, Aleck KA, Botto LD, Herper CL, Kaiser CS, Nabbout R, N'Guyen S, Mora-Lorca JA, Assmann B, Christ S, Meitinger T, Strom TM, Prokisch H; FREX Consortium, Miranda-Vizuete A, Hoffmann GF, Lenaers G, Bomont P, Liebau E, Bonneau D. Biallelic Variants in UBA5 Reveal that Disruption of the UFM1 Cascade Can Result in Early-Onset Encephalopathy. Am J Hum Genet. 2016 Aug 17. pii: S0002-9297(16)30268-3. doi: 10.1016/j.ajhg.2016.06.030. [Epub ahead of print].

G9a and ZNF644 Physically Associate to Suppress Progenitor Gene Expression during Neurogenesis

Authors:
Olsen JB, Wong L, Deimling S, Miles A, Guo H, Li Y, Zhang Z, Greenblatt JF, Emili A, Tropepe V
Citation:
Stem Cell Reports. 2016 Aug 17. pii: S2213-6711(16)30104-7. doi: 10.1016/j.stemcr.2016.06.012. [Epub ahead of print]
Epub:
Yes
Abstract:
Proliferating progenitor cells undergo changes in competence to give rise to post-mitotic progeny of specialized function....
Link:
http://www.cell.com/stem-cell-reports/abstract/S2213-6711(16)30104-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Olsen JB, Wong L, Deimling S, Miles A, Guo H, Li Y, Zhang Z, Greenblatt JF, Emili A, Tropepe V. G9a and ZNF644 Physically Associate to Suppress Progenitor Gene Expression during Neurogenesis. Stem Cell Reports. 2016 Aug 17. pii: S2213-6711(16)30104-7. doi: 10.1016/j.stemcr.2016.06.012. [Epub ahead of print].

Studying cilia in zebrafish

Authors:
Drummond I
Citation:
Methods Cell Biol. 2009;93:197-217. doi: 10.1016/S0091-679X(08)93011-9. Epub 2009 Dec 4
Epub:
Not Epub
Abstract:
Zebrafish are ideally suited for analysis of genes required for ciliogenesis and cilia function. Combining genetic manipulation...
Link:
http://www.sciencedirect.com/science/article/pii/S0091679X08930119
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Drummond I. Studying cilia in zebrafish. Methods Cell Biol. 2009;93:197-217. doi: 10.1016/S0091-679X(08)93011-9. Epub 2009 Dec 4.

Analysis of IFT kinesins in developing zebrafish cone photoreceptor sensory cilia

Authors:
Insinna C, Luby-Phelps K, Link BA, Besharse JC
Citation:
Methods Cell Biol. 2009;93:219-34. doi: 10.1016/S0091-679X(08)93012-0. Epub 2009 Dec 4
Epub:
Not Epub
Abstract:
The photoreceptor outer segment (OS), a well-defined sensory cilium, provides an important context for the study of...
Link:
http://www.sciencedirect.com/science/article/pii/S0091679X08930120
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Insinna C, Luby-Phelps K, Link BA, Besharse JC. Analysis of IFT kinesins in developing zebrafish cone photoreceptor sensory cilia. Methods Cell Biol. 2009;93:219-34. doi: 10.1016/S0091-679X(08)93012-0. Epub 2009 Dec 4.

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