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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Biological effects of 6-formylindolo[3,2-b]carbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner

Authors:
Wincent E, Kubota A, Timme-Laragy A, Jönsson ME, Hahn ME, Stegeman JJ
Citation:
Biochem Pharmacol. 2016 Apr 22. pii: S0006-2952(16)30066-1. doi: 10.1016/j.bcp.2016.04.012. [Epub ahead of print]
Epub:
Yes
Abstract:
6-Formylindolo[3,2-b]carbazole (FICZ) is a potent aryl hydrocarbon receptor (AHR) agonist that is efficiently metabolized by...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wincent E, Kubota A, Timme-Laragy A, Jönsson ME, Hahn ME, Stegeman JJ. Biological effects of 6-formylindolo[3,2-b]carbazole (FICZ) in vivo are enhanced by loss of CYP1A function in an Ahr2-dependent manner. Biochem Pharmacol. 2016 Apr 22. pii: S0006-2952(16)30066-1. doi: 10.1016/j.bcp.2016.04.012. [Epub ahead of print].

sept7b is required for the differentiation of pancreatic endocrine progenitors

Authors:
Dash SN, Hakonen E, Ustinov J, Otonkoski T, Andersson O, Lehtonen S
Citation:
Sci Rep. 2016;6:27992. doi:10.1038/srep24992
Epub:
Not Epub
Abstract:
Protection or restoration of pancreatic β-cell mass as a therapeutic treatment for type 1 diabetes requires understanding of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dash SN, Hakonen E, Ustinov J, Otonkoski T, Andersson O, Lehtonen S. sept7b is required for the differentiation of pancreatic endocrine progenitors. Sci Rep. 2016;6:27992. doi:10.1038/srep24992.

An Electrochemical Study of the Surface Hybridization Process of Morpholino-DNA: Thermodynamics and Kinetics

Authors:
He Y, Zhang J, Ruffin S, Ji L, Wang K, Levicky R, Xia X
Citation:
Electroanalysis. 2016;[Epub ahead of print] doi:10.1002/elan.201501109
Epub:
Not Epub
Abstract:
Morpholino (MO) is a neutral analogue of DNA, which shows promise in the development of DNA biosensors and diagnostic devices....
Citation Extract:
He Y, Zhang J, Ruffin S, Ji L, Wang K, Levicky R, Xia X . An Electrochemical Study of the Surface Hybridization Process of Morpholino-DNA: Thermodynamics and Kinetics. Electroanalysis. 2016;[Epub ahead of print] doi:10.1002/elan.201501109.

Repulsive cues combined with physical barriers and cell-cell adhesion determine progenitor cell positioning during organogenesis

Authors:
Paksa A, Bandemer J, Hoeckendorf B, Razin N, Tarbashevich K, Minina S, Meyen D, Biundo A, Leidel SA, Peyrieras N, Gov NS, Keller PJ, Raz E
Citation:
Nat Commun. 2016 Apr 18;7:11288. doi: 10.1038/ncomms11288
Epub:
Not Epub
Abstract:
The precise positioning of organ progenitor cells constitutes an essential, yet poorly understood step during organogenesis....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Paksa A, Bandemer J, Hoeckendorf B, Razin N, Tarbashevich K, Minina S, Meyen D, Biundo A, Leidel SA, Peyrieras N, Gov NS, Keller PJ, Raz E. Repulsive cues combined with physical barriers and cell-cell adhesion determine progenitor cell positioning during organogenesis. Nat Commun. 2016 Apr 18;7:11288. doi: 10.1038/ncomms11288.

Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development

Authors:
Thyme SB, Schier AF
Citation:
Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.03.072
Epub:
Yes
Abstract:
Error-prone repair of DNA double-strand breaks (DSBs) has been postulated to occur through classical non-homologous end joining...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thyme SB, Schier AF. Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development. Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.03.072.

Cooperative Wnt-Nodal Signals Regulate the Patterning of Anterior Neuroectoderm

Authors:
Yaguchi J, Takeda N, Inaba K, Yaguchi S
Citation:
PLoS Genet. 2016;12(4):e1006001. doi:10.1371/journal.pgen.1006001
Epub:
Not Epub
Abstract:
When early canonical Wnt is experimentally inhibited, sea urchin embryos embody the concept of a Default Model in vivo because...
Delivery Method:
microinjection
Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin)
Citation Extract:
Yaguchi J, Takeda N, Inaba K, Yaguchi S. Cooperative Wnt-Nodal Signals Regulate the Patterning of Anterior Neuroectoderm. PLoS Genet. 2016;12(4):e1006001. doi:10.1371/journal.pgen.1006001.

ESCRT-II controls retinal axon growth by regulating DCC receptor levels and local protein synthesis

Authors:
Konopacki FA, Wong HH-W, Dwivedy A, Bellon A, Blower MD, Holt CE
Citation:
Open Biol. 2016;6:150218. doi:10.1098/rsob.150218
Epub:
Not Epub
Abstract:
Endocytosis and local protein synthesis (LPS) act coordinately to mediate the chemotropic responses of axons, but the link...
Delivery Method:
microinjection, injection then electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Konopacki FA, Wong HH-W, Dwivedy A, Bellon A, Blower MD, Holt CE. ESCRT-II controls retinal axon growth by regulating DCC receptor levels and local protein synthesis. Open Biol. 2016;6:150218. doi:10.1098/rsob.150218.

Knockdown of phosphoethanolamine transmethylation enzymes decreases viability of Haemonchus contortus

Authors:
Witola WH, Cooks-Fagbodun S, Reyes Ordonez AR, Matthews K, Abugri DA, McHugh M
Citation:
Vet Parasitology. 2016;223:1-6. doi:10.1016/j.vetpar.2016.04.008
Epub:
Not Epub
Abstract:
The phosphobase methylation pathway, in which phosphoethanolamine N-methyltransferases (PMTs) successively catalyze the...
Organism or Cell Type:
Haemonchus contortus (barber's pole worm, nematode)
Citation Extract:
Witola WH, Cooks-Fagbodun S, Reyes Ordonez AR, Matthews K, Abugri DA, McHugh M. Knockdown of phosphoethanolamine transmethylation enzymes decreases viability of Haemonchus contortus. Vet Parasitology. 2016;223:1-6. doi:10.1016/j.vetpar.2016.04.008.

SLC7 family transporters control the establishment of left-right asymmetry during organogenesis in medaka by activating mTOR signaling

Authors:
Asaoka Y, Nagai Y, Namae M, Furutani-Seiki M, Nishina H
Citation:
Biochem Biophys Res Commun. 2016 Apr 19. pii: S0006-291X(16)30593-9. doi: 10.1016/j.bbrc.2016.04.087. [Epub ahead of print]
Epub:
Yes
Abstract:
The precise government of the left-right (LR) specification of an organ is an essential aspect of its morphogenesis. Multiple...
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Asaoka Y, Nagai Y, Namae M, Furutani-Seiki M, Nishina H. SLC7 family transporters control the establishment of left-right asymmetry during organogenesis in medaka by activating mTOR signaling. Biochem Biophys Res Commun. 2016 Apr 19. pii: S0006-291X(16)30593-9. doi: 10.1016/j.bbrc.2016.04.087. [Epub ahead of print].

The Fatty Acid Chain Elongase, Elovl1, is Required for Kidney and Swim Bladder Development during Zebrafish Embryogenesis

Authors:
Bhandari S, Lee JN, Kim YI, Nam IK, Kim SJ, Kim SJ, Kwak S, Oh GS, Kim HJ, Yoo HJ, So HS, Choe SK, Park R
Citation:
Organogenesis. 2016 Apr 14:0. [Epub ahead of print]
Epub:
Yes
Abstract:
Very long chain fatty acids are required for sphingolipid synthesis, lipid homeostasis, myelin formation, epidermal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bhandari S, Lee JN, Kim YI, Nam IK, Kim SJ, Kim SJ, Kwak S, Oh GS, Kim HJ, Yoo HJ, So HS, Choe SK, Park R. The Fatty Acid Chain Elongase, Elovl1, is Required for Kidney and Swim Bladder Development during Zebrafish Embryogenesis. Organogenesis. 2016 Apr 14:0. [Epub ahead of print].

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