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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Cyp2aa9 regulates haematopoietic stem cell development in zebrafish

Authors:
Chen J, He J, Li L, Yang D, Luo L
Citation:
Sci Rep. 2016;6:26608. doi:10.1038/srep26608
Epub:
Not Epub
Abstract:
Definitive haematopoiesis occurs during the lifetime of an individual, which continuously replenishes all blood and immune...
Link:
http://www.nature.com/articles/srep26608
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen J, He J, Li L, Yang D, Luo L. Cyp2aa9 regulates haematopoietic stem cell development in zebrafish. Sci Rep. 2016;6:26608. doi:10.1038/srep26608.

Cardiac troponin T is necessary for normal development in the embryonic chick heart

Authors:
England J, Pang KL, Parnall M, Haig MI, Loughna S
Citation:
J Anat. 2016 May 19. doi: 10.1111/joa.12486. [Epub ahead of print]
Epub:
Yes
Abstract:
The heart is the first functioning organ to develop during embryogenesis. The formation of the heart is a tightly regulated and...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/joa.12486/abstract
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
England J, Pang KL, Parnall M, Haig MI, Loughna S. Cardiac troponin T is necessary for normal development in the embryonic chick heart. J Anat. 2016 May 19. doi: 10.1111/joa.12486. [Epub ahead of print].

Elongator Protein 3 (Elp3) stabilizes Snail1 and regulates neural crest migration in Xenopus

Authors:
Yang X, Li J, Zeng W, Li C, Mao B
Citation:
Sci Rep. 2016 May 18;6:26238. doi: 10.1038/srep26238
Epub:
Not Epub
Abstract:
Elongator protein 3 (Elp3) is the enzymatic unit of the elongator protein complex, a histone acetyltransferase complex involved...
Link:
Sci Rep. 2016 May 18;6:26238. doi: 10.1038/srep26238.
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yang X, Li J, Zeng W, Li C, Mao B. Elongator Protein 3 (Elp3) stabilizes Snail1 and regulates neural crest migration in Xenopus. Sci Rep. 2016 May 18;6:26238. doi: 10.1038/srep26238.

The defective expression of gtpbp3 related to tRNA modification alters the mitochondrial function and development of zebrafish

Authors:
Chen D, Li F, Yang Q, Tian M, Zhang Z, Zhang Q, Chen Y, Guan MX
Citation:
Int J Biochem Cell Biol. 2016 May 13. pii: S1357-2725(16)30118-2. doi: 10.1016/j.biocel.2016.05.012. [Epub ahead of print]
Epub:
Yes
Abstract:
Human mitochondrial DNA (mtDNA) mutations have been associated with a wide spectrum of clinical abnormalities. However, nuclear...
Link:
http://www.sciencedirect.com/science/article/pii/S1357272516301182
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen D, Li F, Yang Q, Tian M, Zhang Z, Zhang Q, Chen Y, Guan MX. The defective expression of gtpbp3 related to tRNA modification alters the mitochondrial function and development of zebrafish. Int J Biochem Cell Biol. 2016 May 13. pii: S1357-2725(16)30118-2. doi: 10.1016/j.biocel.2016.05.012. [Epub ahead of print].

Reiterative expression of pax1 directs pharyngeal pouch segmentation in medaka

Authors:
Okada K, Inohaya K, Mise T, Kudo A, Takada S, Wada H
Citation:
Development. 2016 May 15;143(10):1800-1810. Epub 2016 Mar 31
Epub:
Not Epub
Abstract:
A striking characteristic of vertebrate development is the pharyngeal arches, which are a series of bulges on the lateral...
Link:
http://dev.biologists.org/content/143/10/1800.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Okada K, Inohaya K, Mise T, Kudo A, Takada S, Wada H. Reiterative expression of pax1 directs pharyngeal pouch segmentation in medaka. Development. 2016 May 15;143(10):1800-1810. Epub 2016 Mar 31.

Protective effect of prostacyclin against pre-cardiac edema caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin and a thromboxane receptor agonist in developing zebrafish

Authors:
Nijoukubo D, Tanaka Y, Okuno Y, Yin G, Kitazawa T, Peterson RE, Kubota A, Teraoka H
Citation:
Chemosphere. 2016 May 9;156:111-117. doi: 10.1016/j.chemosphere.2016.04.107. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The role of prostaglandin pathways has been suggested in some toxicological responses to dioxins. Cyclooxygenase type 2b (COX2b...
Link:
http://www.sciencedirect.com/science/article/pii/S0045653516305975
Organism or Cell Type:
zebrafish
Citation Extract:
Nijoukubo D, Tanaka Y, Okuno Y, Yin G, Kitazawa T, Peterson RE, Kubota A, Teraoka H. Protective effect of prostacyclin against pre-cardiac edema caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin and a thromboxane receptor agonist in developing zebrafish. Chemosphere. 2016 May 9;156:111-117. doi: 10.1016/j.chemosphere.2016.04.107. [Epub ahead of print].

Fluorescence Detection of DNA Based on Non-covalent π-π Stacking Interaction between 1-Pyrenebutanoic Acid and Hypericin

Authors:
Hu W, Zhang J, Kong J
Citation:
Anal Sci. 2016;32(5):523-7. doi: 10.2116/analsci.32.523
Epub:
Not Epub
Abstract:
Herein, we applied hypericin (Hyp) for the detection of DNA on streptavidin-functionalized magnetic beads (SA-MB) through non-...
Link:
https://www.jstage.jst.go.jp/article/analsci/32/5/32_523/_article
Citation Extract:
Hu W, Zhang J, Kong J. Fluorescence Detection of DNA Based on Non-covalent π-π Stacking Interaction between 1-Pyrenebutanoic Acid and Hypericin. Anal Sci. 2016;32(5):523-7. doi: 10.2116/analsci.32.523.

Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures

Authors:
Wang X, Tucker NR, Rizki G, Mills R, Krijger PH, de Wit E, Subramanian V, Bartell E, Nguyen XX, Ye J, Leyton-Mange J, Dolmatova EV, van der Harst P, de Laat W, Ellinor PT, Newton-Cheh C, Milan DJ, Kellis M, Boyer LA
Citation:
Elife. 2016 May 10;5. pii: e10557. doi: 10.7554/eLife.10557
Epub:
Not Epub
Abstract:
Genetic variants identified by genome-wide association studies explain only a modest proportion of heritability, suggesting...
Link:
https://elifesciences.org/content/5/e10557
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang X, Tucker NR, Rizki G, Mills R, Krijger PH, de Wit E, Subramanian V, Bartell E, Nguyen XX, Ye J, Leyton-Mange J, Dolmatova EV, van der Harst P, de Laat W, Ellinor PT, Newton-Cheh C, Milan DJ, Kellis M, Boyer LA. Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures. Elife. 2016 May 10;5. pii: e10557. doi: 10.7554/eLife.10557.

Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment

Authors:
Sintusek P, Catapano F, Angkathunkayul N, Marrosu E, Parson SH, Morgan JE, Muntoni F, Zhou H
Citation:
PLoS One. 2016 May 10;11(5):e0155032. doi: 10.1371/journal.pone.0155032. eCollection 2016
Epub:
Not Epub
Abstract:
Gastrointestinal (GI) defects, including gastroesophageal reflux, constipation and delayed gastric emptying, are common in...
Link:
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0155032
Delivery Method:
subcutaneous injection
Organism or Cell Type:
mice
Citation Extract:
Sintusek P, Catapano F, Angkathunkayul N, Marrosu E, Parson SH, Morgan JE, Muntoni F, Zhou H. Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment. PLoS One. 2016 May 10;11(5):e0155032. doi: 10.1371/journal.pone.0155032. eCollection 2016.

Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia

Authors:
Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gumus ZH, Cicek AE, Dang K, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Parvisi M, Hamamsy T, Fullard JF, Wang Y-C, Mahajan MC, Derry JMJ, Dudley J, Hemby SE, Logsdon BA, Talbot K, Raj T, Bennett DA, De Jager PL, Zhu J, Zhang B, Sullivan PF, Chess A, Purcell SM, Shinobu LA, Mangravite LM, Toyoshiba H, Gur RE, Hahn C-G, Lewis DA, Haroutonian V, Peters MA, Lipska BK, Buxbaum JD, Schadt EE, Hira K, Roeder K, Brennand KJ, Katsanis N, Dominici E, Devlin B, Sklar P
Citation:
bioRxiv. 2016. doi:10.1101/052209
Epub:
Yes
Abstract:
Over 100 genetic loci harbor schizophrenia associated variants, yet how these common variants confer risk is uncertain. The...
Link:
http://biorxiv.org/content/early/2016/05/09/052209
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gumus ZH, Cicek AE, Dang K, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Parvisi M, Hamamsy T, Fullard JF, Wang Y-C, Mahajan MC, Derry JMJ, Dudley J, Hemby SE, Logsdon BA, Talbot K, Raj T, Bennett DA, De Jager PL, Zhu J, Zhang B, Sullivan PF, Chess A, Purcell SM, Shinobu LA, Mangravite LM, Toyoshiba H, Gur RE, Hahn C-G, Lewis DA, Haroutonian V, Peters MA, Lipska BK, Buxbaum JD, Schadt EE, Hira K, Roeder K, Brennand KJ, Katsanis N, Dominici E, Devlin B, Sklar P. Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia. bioRxiv. 2016. doi:10.1101/052209.

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