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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis

Authors:
Steed E, Faggianelli N, Roth S, Ramspacher C, Concordet J-P, Vermot J
Citation:
Nat Comm. 2016;7:11646. doi:10.1038/ncomms11646
Epub:
Not Epub
Abstract:
The heartbeat and blood flow signal to endocardial cell progenitors through mechanosensitive proteins that modulate the genetic...
Link:
http://www.nature.com/ncomms/2016/160525/ncomms11646/full/ncomms11646.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Steed E, Faggianelli N, Roth S, Ramspacher C, Concordet J-P, Vermot J. klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis. Nat Comm. 2016;7:11646. doi:10.1038/ncomms11646.

The polycystin complex mediates Wnt/Ca2+ signalling

Authors:
Kim S, Nie H, Nesin V, Tran U, Outeda P, Bai CX, Keeling J, Maskey D, Watnick T, Wessely O, Tsiokas L
Citation:
Nat Cell Biol. 2016 May 23. doi: 10.1038/ncb3363. [Epub ahead of print]
Epub:
Yes
Abstract:
WNT ligands induce Ca2+ signalling on target cells. PKD1 (polycystin 1) is considered an orphan, atypical G-protein-coupled...
Link:
http://www.nature.com/ncb/journal/vaop/ncurrent/full/ncb3363.html
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kim S, Nie H, Nesin V, Tran U, Outeda P, Bai CX, Keeling J, Maskey D, Watnick T, Wessely O, Tsiokas L. The polycystin complex mediates Wnt/Ca2+ signalling. Nat Cell Biol. 2016 May 23. doi: 10.1038/ncb3363. [Epub ahead of print].

Open and closed evolutionary paths for drastic morphological changes, involving serial gene duplication, sub-functionalization, and selection

Authors:
Abe G, Lee S-H, Li I-J, Chang C-J, Tamura K,Ota KG
Citation:
Sci Rep. 2016;6:26838. doi:10.1038/srep26838
Epub:
Not Epub
Abstract:
Twin-tail goldfish strains are examples of drastic morphological alterations that emerged through domestication. Although this...
Link:
http://www.nature.com/articles/srep26838
Delivery Method:
microinjection
Organism or Cell Type:
Carassius auratus (goldfish), Cyprinus carpio (common carp)
Citation Extract:
Abe G, Lee S-H, Li I-J, Chang C-J, Tamura K,Ota KG. Open and closed evolutionary paths for drastic morphological changes, involving serial gene duplication, sub-functionalization, and selection. Sci Rep. 2016;6:26838. doi:10.1038/srep26838.

NANS-mediated synthesis of sialic acid is required for brain and skeletal development

Authors:
van Karnebeek CD, Bonafé L, Wen XY, Tarailo-Graovac M, Balzano S, Royer-Bertrand B, Ashikov A, Garavelli L, Mammi I, Turolla L, Breen C, Donnai D, Cormier V, Heron D, Nishimura G, Uchikawa S, Campos-Xavier B, Rossi A, Hennet T, Brand-Arzamendi K, Rozmus J, Harshman K, Stevenson BJ, Girardi E, Superti-Furga G, Dewan T, Collingridge A, Halparin J, Ross CJ, Van Allen MI, Rossi A, Engelke UF, Kluijtmans LA, van der Heeft E, Renkema H, de Brouwer A, Huijben K, Zijlstra F, Heisse T, Boltje T, Wasserman WW, Rivolta C, Unger S, Lefeber DJ, Wevers RA, Superti-Furga A
Citation:
Nat Genet. 2016 May 23. doi: 10.1038/ng.3578. [Epub ahead of print]
Epub:
Yes
Abstract:
We identified biallelic mutations in NANS, the gene encoding the synthase for N-acetylneuraminic acid (NeuNAc; sialic acid), in...
Link:
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3578.html
Organism or Cell Type:
zebrafish
Citation Extract:
van Karnebeek CD, Bonafé L, Wen XY, Tarailo-Graovac M, Balzano S, Royer-Bertrand B, Ashikov A, Garavelli L, Mammi I, Turolla L, Breen C, Donnai D, Cormier V, Heron D, Nishimura G, Uchikawa S, Campos-Xavier B, Rossi A, Hennet T, Brand-Arzamendi K, Rozmus J, Harshman K, Stevenson BJ, Girardi E, Superti-Furga G, Dewan T, Collingridge A, Halparin J, Ross CJ, Van Allen MI, Rossi A, Engelke UF, Kluijtmans LA, van der Heeft E, Renkema H, de Brouwer A, Huijben K, Zijlstra F, Heisse T, Boltje T, Wasserman WW, Rivolta C, Unger S, Lefeber DJ, Wevers RA, Superti-Furga A. NANS-mediated synthesis of sialic acid is required for brain and skeletal development. Nat Genet. 2016 May 23. doi: 10.1038/ng.3578. [Epub ahead of print].

Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish

Authors:
Giacomotto J, Carroll AP, Rinkwitz S, Mowry B, Cairns MJ, Becker TS
Citation:
Transl Psychiatry. 2016 May 24;6:e818. doi: 10.1038/tp.2016.88
Epub:
Not Epub
Abstract:
The neurodevelopmentally regulated microRNA miR-137 was strongly implicated as risk locus for schizophrenia in the most recent...
Link:
http://www.nature.com/tp/journal/v6/n5/full/tp201688a.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Giacomotto J, Carroll AP, Rinkwitz S, Mowry B, Cairns MJ, Becker TS. Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish. Transl Psychiatry. 2016 May 24;6:e818. doi: 10.1038/tp.2016.88.

The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly

Authors:
Smith SJ, Towers N, Saldanha JW, Shang CA, Mahmood SR, Taylor WR, Mohun TJ
Citation:
Dev Biol. 2016 May 20. pii: S0012-1606(15)30138-X. doi: 10.1016/j.ydbio.2016.05.006. [Epub ahead of print]
Epub:
Yes
Abstract:
Adprhl1, a member of the ADP-ribosylhydrolase protein family, is expressed exclusively in the developing heart of all...
Link:
http://www.sciencedirect.com/science/article/pii/S001216061530138X
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Smith SJ, Towers N, Saldanha JW, Shang CA, Mahmood SR, Taylor WR, Mohun TJ. The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly. Dev Biol. 2016 May 20. pii: S0012-1606(15)30138-X. doi: 10.1016/j.ydbio.2016.05.006. [Epub ahead of print].

Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and cyp1a inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus)

Authors:
Brown DR, Clark BW, Garner LV, Di Giulio RT
Citation:
Comp Biochem Physiol C Toxicol Pharmacol. 2016 May 20. pii: S1532-0456(16)30062-X. doi: 10.1016/j.cbpc.2016.05.005. [Epub ahead of print]
Epub:
Not Epub
Abstract:
High affinity aryl hydrocarbon receptor (AHR) ligands, such as certain polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo...
Link:
http://www.sciencedirect.com/science/article/pii/S153204561630062X
Delivery Method:
microinjection
Organism or Cell Type:
Fundulus heteroclitus (killifish)
Citation Extract:
Brown DR, Clark BW, Garner LV, Di Giulio RT. Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and cyp1a inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus). Comp Biochem Physiol C Toxicol Pharmacol. 2016 May 20. pii: S1532-0456(16)30062-X. doi: 10.1016/j.cbpc.2016.05.005. [Epub ahead of print].

Macrophage development from HSCs requires PU.1-coordinated microRNA expression

Authors:
Ghani S, Riemke P, Schönheit J, Lenze D, Stumm J, Hoogenkamp M, Lagendijk A, Heinz S, Bonifer C, Bakkers J, Abdelilah-Seyfried S, Hummel M, Rosenbauer F
Citation:
Blood. 2011 Aug 25;118(8):2275-84. doi: 10.1182/blood-2011-02-335141. Epub 2011 Jul 5
Epub:
Not Epub
Abstract:
The differentiation of HSCs into myeloid lineages requires the transcription factor PU.1. Whereas PU.1-dependent induction of...
Link:
http://www.bloodjournal.org/content/118/8/2275.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ghani S, Riemke P, Schönheit J, Lenze D, Stumm J, Hoogenkamp M, Lagendijk A, Heinz S, Bonifer C, Bakkers J, Abdelilah-Seyfried S, Hummel M, Rosenbauer F. Macrophage development from HSCs requires PU.1-coordinated microRNA expression. Blood. 2011 Aug 25;118(8):2275-84. doi: 10.1182/blood-2011-02-335141. Epub 2011 Jul 5.

Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing

Authors:
Popov IK, Kwon T, Crossman DK, Crowley MR, Wallingford JB, Chang C
Citation:
Dev Biol. 2016 May 18. pii: S0012-1606(16)30125-7. doi: 10.1016/j.ydbio.2016.05.014. [Epub ahead of print]
Epub:
Yes
Abstract:
During early vertebrate embryogenesis, cell fate specification is often coupled with cell acquisition of specific adhesive,...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616301257
Organism or Cell Type:
Xenopus
Citation Extract:
Popov IK, Kwon T, Crossman DK, Crowley MR, Wallingford JB, Chang C. Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing. Dev Biol. 2016 May 18. pii: S0012-1606(16)30125-7. doi: 10.1016/j.ydbio.2016.05.014. [Epub ahead of print].

Calmodulin Mediates Ca2+-Dependent Inhibition of Tie2 Signaling and Acts as a Developmental Brake During Embryonic Angiogenesis

Authors:
Yang C, Ohk J, Lee JY, Kim EJ, Kim J, Han S, Park D, Jung H, Kim C
Citation:
Arterioscler Thromb Vasc Biol. 2016 May 19. pii: ATVBAHA.116.307619. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVE: Angiogenesis, the process of building complex vascular structures, begins with sprout formation on preexisting blood...
Link:
http://atvb.ahajournals.org/content/early/2016/05/19/ATVBAHA.116.307619.abstract
Organism or Cell Type:
Xenopus
Citation Extract:
Yang C, Ohk J, Lee JY, Kim EJ, Kim J, Han S, Park D, Jung H, Kim C. Calmodulin Mediates Ca2+-Dependent Inhibition of Tie2 Signaling and Acts as a Developmental Brake During Embryonic Angiogenesis. Arterioscler Thromb Vasc Biol. 2016 May 19. pii: ATVBAHA.116.307619. [Epub ahead of print].

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