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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Hepcidin inhibition on the effect of osteogenesis in zebrafish

Authors:
Jiang Y, Yan Y, Wang X, Zhu G, Xu YJ
Citation:
Biochem Biophys Res Commun. 2016 May 24. pii: S0006-291X(16)30826-9. doi: 10.1016/j.bbrc.2016.05.118. [Epub ahead of print]
Epub:
Yes
Abstract:
Iron overload, as a risk factor for osteoporosis, can result in the up-regulation of Hepcidin, and Hepcidin knockout mice...
Link:
http://www.sciencedirect.com/science/article/pii/S0006291X16308269
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jiang Y, Yan Y, Wang X, Zhu G, Xu YJ. Hepcidin inhibition on the effect of osteogenesis in zebrafish. Biochem Biophys Res Commun. 2016 May 24. pii: S0006-291X(16)30826-9. doi: 10.1016/j.bbrc.2016.05.118. [Epub ahead of print].

Reprofiling using a zebrafish melanoma model reveals drugs cooperating with targeted therapeutics

Authors:
del Ama LF, Jones M, Walker P, Chapman A, Braun JA, Mohr J, Hurlstone AFL
Citation:
Oncotarget. 2016;[Epub ahead of print] doi:10.18632/oncotarget.9613
Epub:
Yes
Abstract:
Phenotype-guided re-profiling of approved drug molecules presents an accelerated route to developing anticancer therapeutics by...
Link:
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path[]=9613&path[]=30104
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
del Ama LF, Jones M, Walker P, Chapman A, Braun JA, Mohr J, Hurlstone AFL. Reprofiling using a zebrafish melanoma model reveals drugs cooperating with targeted therapeutics. Oncotarget. 2016;[Epub ahead of print] doi:10.18632/oncotarget.9613.

Pre-bilaterian origin of the blastoporal axial organizer

Authors:
Kraus Y, Aman A, Technau U, Genikhovich G
Citation:
Nat Comm. 2016;7:11694. doi:10.1038/ncomms11694
Epub:
Not Epub
Abstract:
The startling capacity of the amphibian Spemann organizer to induce naïve cells to form a Siamese twin embryo with a second set...
Link:
http://www.nature.com/ncomms/2016/160527/ncomms11694/full/ncomms11694.html
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Kraus Y, Aman A, Technau U, Genikhovich G. Pre-bilaterian origin of the blastoporal axial organizer. Nat Comm. 2016;7:11694. doi:10.1038/ncomms11694.

Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin

Authors:
Gouignard N, Maccarana M, Strate I, von Stedingk K, Malmström A, Pera EM
Citation:
Dis Model Mech. 2016 Apr 21. pii: dmm.024661. [Epub ahead of print]
Epub:
Yes
Abstract:
Of all live births with congenital anomalies, approximately one-third exhibit deformities of the head and face. Most...
Link:
http://dmm.biologists.org/content/9/6/607
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gouignard N, Maccarana M, Strate I, von Stedingk K, Malmström A, Pera EM. Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin. Dis Model Mech. 2016 Apr 21. pii: dmm.024661. [Epub ahead of print].

Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor

Authors:
Daakour S, Hajingabo LJ, Kerselidou D, Aurelie Devresse A, Kettmann R, Simonis N, Dequiedt F, Twizere J-C
Citation:
BMC Cancer. 2016;16:335 doi:10.1186/s12885-016-2374-2
Epub:
Not Epub
Abstract:
Background: Perturbed genotypes in cancer can now be identified by whole genome sequencing of large number of diverse tumor...
Link:
http://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2374-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Daakour S, Hajingabo LJ, Kerselidou D, Aurelie Devresse A, Kettmann R, Simonis N, Dequiedt F, Twizere J-C. Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor. BMC Cancer. 2016;16:335 doi:10.1186/s12885-016-2374-2.

A pancreatic exocrine-like cell regulatory circuit operating in the upper stomach of the sea urchin Strongylocentrotus purpuratus larva

Authors:
Perillo M, Wang YJ, Leach SD, Arnone MI
Citation:
BMC Evol Biol. 2016;16:117 doi:10.1186/s12862-016-0686-0
Epub:
Not Epub
Abstract:
Background: Digestive cells are present in all metazoans and provide the energy necessary for the whole organism. Pancreatic...
Link:
http://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-016-0686-0
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Perillo M, Wang YJ, Leach SD, Arnone MI. A pancreatic exocrine-like cell regulatory circuit operating in the upper stomach of the sea urchin Strongylocentrotus purpuratus larva. BMC Evol Biol. 2016;16:117 doi:10.1186/s12862-016-0686-0.

EZH2 is required for mouse oocyte meiotic maturation by interacting with and stabilizing spindle assembly checkpoint protein BubRI

Authors:
Qu Y, Lu D, Jiang H, Chi X, Zhang H
Citation:
Nucl Acid Res. 2016;[epub ahead of print] doi: 10.1093/nar/gkw463
Epub:
Yes
Abstract:
Enhancer of zeste homolog 2 (EZH2) trimethylates histone H3 Lys 27 and plays key roles in a variety of biological processes....
Link:
http://nar.oxfordjournals.org/content/early/2016/05/25/nar.gkw463.full
Citation Extract:
Qu Y, Lu D, Jiang H, Chi X, Zhang H. EZH2 is required for mouse oocyte meiotic maturation by interacting with and stabilizing spindle assembly checkpoint protein BubRI. Nucl Acid Res. 2016;[epub ahead of print] doi: 10.1093/nar/gkw463.

Foxa2 and Hif1ab regulate maturation of intestinal goblet cells by modulating agr2 expression in zebrafish embryos

Authors:
Lai YR, Lu YF, Lien HW, Huang CJ, Hwang SL
Citation:
Biochem J. 2016 May 24. pii: BCJ20160392. [Epub ahead of print]
Epub:
Yes
Abstract:
Mammalian anterior gradient 2 (AGR2), an endoplasmic reticulum protein disulfide isomerase, is involved in cancer cell growth...
Link:
http://www.biochemj.org/content/early/2016/05/24/BCJ20160392
Organism or Cell Type:
zebrafish
Citation Extract:
Lai YR, Lu YF, Lien HW, Huang CJ, Hwang SL. Foxa2 and Hif1ab regulate maturation of intestinal goblet cells by modulating agr2 expression in zebrafish embryos. Biochem J. 2016 May 24. pii: BCJ20160392. [Epub ahead of print].

Solid-phase-supported synthesis of morpholino-glycine oligonucleotide mimics.

Authors:
Abramova TV, Belov SS, Tarasenko YV, Silnikov VN
Citation:
Beilstein J Org Chem. 2014;10:1151-8. doi:10.3762/bjoc.10.115
Epub:
Not Epub
Abstract:
Efficient solid phase supported peptide synthesis (SPPS) of morpholino glycine oligonucleotide (MorGLy) mimics has been...
Link:
http://www.beilstein-journals.org/bjoc/single/articleFullText.htm?publicId=1860-5397-10-115
Citation Extract:
Abramova TV, Belov SS, Tarasenko YV, Silnikov VN. Solid-phase-supported synthesis of morpholino-glycine oligonucleotide mimics.. Beilstein J Org Chem. 2014;10:1151-8. doi:10.3762/bjoc.10.115.

Development of the aboral domain in Nematostella requires β-catenin and the opposing activities of Six3/6 and Frizzled5/8

Authors:
Leclère L, Bause M, Sinigaglia C, Steger J, Rentzsch F
Citation:
Development. 2016;143:1766-1777. doi: 10.1242/dev.120931
Epub:
Not Epub
Abstract:
The development of the oral pole in cnidarians and the posterior pole in bilaterians is regulated by canonical Wnt signaling,...
Link:
http://dev.biologists.org/content/143/10/1766
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Leclère L, Bause M, Sinigaglia C, Steger J, Rentzsch F. Development of the aboral domain in Nematostella requires β-catenin and the opposing activities of Six3/6 and Frizzled5/8. Development. 2016;143:1766-1777. doi: 10.1242/dev.120931 .

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