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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Spatiotemporal expression and transcriptional regulation of heme oxygenase and biliverdin reductase genes in zebrafish (Danio rerio) suggest novel roles during early developmental periods of heightened oxidative stress

Authors:
Holowiecki A, O'Shields B, Jenny MJ
Citation:
Comp Biochem Physiol C Toxicol Pharmacol. 2016 Oct 17. pii: S1532-0456(16)30132-6. doi: 10.1016/j.cbpc.2016.10.006
Epub:
Yes
Abstract:
Heme oxygenase 1 (HMOX1) degrades heme into biliverdin, which is subsequently converted to bilirubin by biliverdin reductase (...
Link:
http://www.sciencedirect.com/science/article/pii/S1532045616301326
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Holowiecki A, O'Shields B, Jenny MJ. Spatiotemporal expression and transcriptional regulation of heme oxygenase and biliverdin reductase genes in zebrafish (Danio rerio) suggest novel roles during early developmental periods of heightened oxidative stress. Comp Biochem Physiol C Toxicol Pharmacol. 2016 Oct 17. pii: S1532-0456(16)30132-6. doi: 10.1016/j.cbpc.2016.10.006.

The zebrafish homologs of SET/I2PP2A oncoprotein: expression patterns and insights into their physiological roles during development

Authors:
Serifi I, Tzima E, Soupsana K, Karetsou Z, Beis D, Papamarcaki T
Citation:
Biochem J. 2016 Oct 17. pii: BCJ20160523 [epub ahead of print]. doi:10.1042/BCJ20160523
Epub:
Yes
Abstract:
The oncoprotein SET/I2PP2A participates in various cellular mechanisms such as transcription, cell cycle regulation and cell...
Link:
http://www.biochemj.org/content/early/2016/10/17/BCJ20160523.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Serifi I, Tzima E, Soupsana K, Karetsou Z, Beis D, Papamarcaki T. The zebrafish homologs of SET/I2PP2A oncoprotein: expression patterns and insights into their physiological roles during development. Biochem J. 2016 Oct 17. pii: BCJ20160523 [epub ahead of print]. doi:10.1042/BCJ20160523.

Loss of a Candidate Biliary Atresia Susceptibility Gene, add3a, Causes Biliary Developmental Defects in Zebrafish

Authors:
Tang V, Cofer ZC, Cui S, Sapp V, Loomes KM, Matthews RP
Citation:
J Pediatr Gastroenterol Nutr. 2016 Nov;63(5):524-530. doi:10.1097/MPG.0000000000001375
Epub:
Not Epub
Abstract:
OBJECTIVES: Biliary atresia (BA) is a progressive fibroinflammatory cholangiopathy affecting the bile ducts of neonates....
Link:
http://journals.lww.com/jpgn/Fulltext/2016/11000/Loss_of_a_Candidate_Biliary_Atresia_Susceptibility.15.aspx
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tang V, Cofer ZC, Cui S, Sapp V, Loomes KM, Matthews RP. Loss of a Candidate Biliary Atresia Susceptibility Gene, add3a, Causes Biliary Developmental Defects in Zebrafish. J Pediatr Gastroenterol Nutr. 2016 Nov;63(5):524-530. doi:10.1097/MPG.0000000000001375.

Mutation in SSUH2 Causes Autosomal-Dominant Dentin Dysplasia Type I

Authors:
Xiong F, Ji Z, Liu Y, Zhang Y, Hu L, Yang Q, Qiu Q, Zhao L, Chen D, Tian Z, Shang X, Zhang L, Wei X, Liu C, Yu Q, Zhang M, Cheng J, Xiong J, Li D, Wu X, Yuan H, Zhang W, Xu X
Citation:
Hum Mutat. 2016 Sep 29. doi: 10.1002/humu.23130
Epub:
Yes
Abstract:
Dentin dysplasia type I (DDI) is an autosomal-dominant genetic disorder resulting from dentin defects. The molecular basis of...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/humu.23130/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xiong F, Ji Z, Liu Y, Zhang Y, Hu L, Yang Q, Qiu Q, Zhao L, Chen D, Tian Z, Shang X, Zhang L, Wei X, Liu C, Yu Q, Zhang M, Cheng J, Xiong J, Li D, Wu X, Yuan H, Zhang W, Xu X. Mutation in SSUH2 Causes Autosomal-Dominant Dentin Dysplasia Type I. Hum Mutat. 2016 Sep 29. doi: 10.1002/humu.23130.

HIF1α-induced PDGFRβ signaling promotes developmental HSC production via IL-6 activation

Authors:
Lim SE, Esain V, Kwan W, Theodore LN, Cortes M, Frost IM, Liu SY, North TE
Citation:
Exp Hematol. 2016 Oct 14. pii: S0301-472X(16)30657-9. [Epub ahead of print] doi: 10.1016/j.exphem.2016.10.002
Epub:
Yes
Abstract:
Hematopoietic stem cells (HSCs) have the ability to both self-renew and differentiate into all the mature blood cell lineages...
Link:
http://www.exphem.org/article/S0301-472X(16)30657-9/abstract
Citation Extract:
Lim SE, Esain V, Kwan W, Theodore LN, Cortes M, Frost IM, Liu SY, North TE. HIF1α-induced PDGFRβ signaling promotes developmental HSC production via IL-6 activation. Exp Hematol. 2016 Oct 14. pii: S0301-472X(16)30657-9. [Epub ahead of print] doi: 10.1016/j.exphem.2016.10.002.

Expression of SoxC Transcription Factors during Zebrafish Retinal and Optic Nerve Regeneration

Authors:
Mu Z, Zhang S, He C, Hou H, Liu D, Hu N, Xu H
Citation:
Neurosci Bull. 2016 Oct 14:[Epub ahead of print] doi: 10.1007/s12264-016-0073-2
Epub:
Yes
Abstract:
The SoxC transcription factors (Sox4, Sox11, and Sox12) play important roles in the development of the vertebrate eye and...
Link:
http://link.springer.com/article/10.1007%2Fs12264-016-0073-2
Organism or Cell Type:
zebrafish
Citation Extract:
Mu Z, Zhang S, He C, Hou H, Liu D, Hu N, Xu H. Expression of SoxC Transcription Factors during Zebrafish Retinal and Optic Nerve Regeneration. Neurosci Bull. 2016 Oct 14:[Epub ahead of print] doi: 10.1007/s12264-016-0073-2.

Facile and phase-defined determination of HLA alleles with morpholino-functionalized nanoparticle probes

Authors:
Zu Y, Tan MH, Ren EC, Ying JY
Citation:
Nanomedicine. 2016 Oct 5. pii: S1549-9634(16)30161-7. doi: 10.1016/j.nano.2016.09.009 [Epub ahead of print] doi:10.1016/j.nano.2016.09.009
Epub:
Yes
Abstract:
A number of human leukocyte antigen (HLA) gene alleles have been found to be genetic risk markers for immunologically mediated...
Link:
http://www.nanomedjournal.com/article/S1549-9634(16)30161-7/abstract
Citation Extract:
Zu Y, Tan MH, Ren EC, Ying JY. Facile and phase-defined determination of HLA alleles with morpholino-functionalized nanoparticle probes. Nanomedicine. 2016 Oct 5. pii: S1549-9634(16)30161-7. doi: 10.1016/j.nano.2016.09.009 [Epub ahead of print] doi:10.1016/j.nano.2016.09.009.

Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish

Authors:
Lim KH, Chang YC, Chiang YH, Lin HC, Chang CY, Lin CS, Huang L, Wang WT, Gon-Shen Chen C, Chou WC, Kuo YY
Citation:
Blood Cancer J. 2016 Oct 7;6(10):e481. doi: 10.1038/bcj.2016.83
Epub:
Not Epub
Abstract:
CALR mutations are identified in about 30% of JAK2/MPL-unmutated myeloproliferative neoplasms (MPNs) including essential...
Link:
http://www.nature.com/bcj/journal/v6/n10/full/bcj201683a.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lim KH, Chang YC, Chiang YH, Lin HC, Chang CY, Lin CS, Huang L, Wang WT, Gon-Shen Chen C, Chou WC, Kuo YY. Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish. Blood Cancer J. 2016 Oct 7;6(10):e481. doi: 10.1038/bcj.2016.83.

Effects of Cyclin Dependent Kinase 9 inhibition on zebrafish larvae

Authors:
Matrone G, Mullins JJ, Tucker CS, Denvir MA
Citation:
Cell Cycle. 2016 Oct 7: [Epub ahead of print] doi:10.1080/15384101.2016.1231283
Epub:
Yes
Abstract:
CDK9 is a known regulator of cellular transcription, growth and proliferation. Small molecule inhibitors are currently being...
Link:
http://www.tandfonline.com/doi/full/10.1080/15384101.2016.1231283
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Matrone G, Mullins JJ, Tucker CS, Denvir MA. Effects of Cyclin Dependent Kinase 9 inhibition on zebrafish larvae. Cell Cycle. 2016 Oct 7: [Epub ahead of print] doi:10.1080/15384101.2016.1231283.

Antagonism between β-catenin and Gata.a sequentially segregates the germ layers of ascidian embryos

Authors:
Imai KS, Hudson C, Oda-Ishii I, Yasuo H, Satou Y
Citation:
Development. 2016;[Epub ahead of print] doi: 10.1242/dev.141481
Epub:
Not Epub
Abstract:
Many animal embryos use nuclear β-catenin (nβ-catenin) during the segregation of endomesoderm (or endoderm) from ectoderm. This...
Link:
http://dev.biologists.org/content/early/2016/10/04/dev.141481
Delivery Method:
microinjection
Citation Extract:
Imai KS, Hudson C, Oda-Ishii I, Yasuo H, Satou Y. Antagonism between β-catenin and Gata.a sequentially segregates the germ layers of ascidian embryos. Development. 2016;[Epub ahead of print] doi: 10.1242/dev.141481.

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