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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Identification and Validation of Small-Gatekeeper Kinases as Drug Targets in Giardia lamblia
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Citation:
PLoS Negl Trop Dis. 2016 Nov 2;10(11):e0005107. doi: 10.1371/journal.pntd.0005107 Epub:
Not Epub Abstract:
Giardiasis is widely acknowledged to be a neglected disease in need of new therapeutics to address toxicity and resistance... Delivery Method:
electroporation Organism or Cell Type:
Giardia lamblia Citation Extract: Hennessey KM, Smith TR, Xu JW, Alas GC, Ojo KK, Merritt EA, Paredez AR. Identification and Validation of Small-Gatekeeper Kinases as Drug Targets in Giardia lamblia. PLoS Negl Trop Dis. 2016 Nov 2;10(11):e0005107. doi: 10.1371/journal.pntd.0005107. |
Functional antagonism of alpha-subunits of Kv channel in developing brain ventricular system
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Citation:
Development. 2016 Oct 11. pii: dev.140467. [Epub ahead of print] Epub:
Yes Abstract:
The brain ventricular system is essential for neurogenesis and brain homeostasis. Its neuroepithelial lining effects these... Organism or Cell Type:
zebrafish Citation Extract: Shen H, Bocksteins E, Kondrychyn I, Snyders D, Korzh V. Functional antagonism of alpha-subunits of Kv channel in developing brain ventricular system. Development. 2016 Oct 11. pii: dev.140467. [Epub ahead of print]. |
Variants in the Oxidoreductase PYROXD1 Cause Early-Onset Myopathy with Internalized Nuclei and Myofibrillar Disorganization
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Citation:
Am J Hum Genet. 2016 Sep 28. pii: S0002-9297(16)30385-8. doi: 10.1016/j.ajhg.2016.09.005. [Epub ahead of print] Epub:
Yes Abstract:
This study establishes PYROXD1 variants as a cause of early-onset myopathy and uses biospecimens and cell lines, yeast, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: O'Grady GL, Best HA, Sztal TE, Schartner V, Sanjuan-Vazquez M, Donkervoort S, Abath Neto O, Sutton RB, Ilkovski B, Romero NB, Stojkovic T, Dastgir J, Waddell LB, Boland A, Hu Y, Williams C, Ruparelia AA, Maisonobe T, Peduto AJ, Reddel SW, Lek M, Tukiainen T, Cummings BB, Joshi H, Nectoux J, Brammah S, Deleuze JF, Ing VO, Ramm G, Ardicli D, Nowak KJ, Talim B, Topaloglu H, Laing NG, North KN, MacArthur DG, Friant S, Clarke NF, Bryson-Richardson RJ, Bönnemann CG, Laporte J, Cooper ST. Variants in the Oxidoreductase PYROXD1 Cause Early-Onset Myopathy with Internalized Nuclei and Myofibrillar Disorganization. Am J Hum Genet. 2016 Sep 28. pii: S0002-9297(16)30385-8. doi: 10.1016/j.ajhg.2016.09.005. [Epub ahead of print]. |
Zebrafish as a Model to Study Cohesin and Cohesinopathies
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Citation:
Methods Mol Biol. 2017;1515:177-196 Epub:
Not Epub Abstract:
The cohesin protein complex regulates multiple cellular events including sister chromatid cohesion and gene expression. Several... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Muto A, Schilling TF. Zebrafish as a Model to Study Cohesin and Cohesinopathies. Methods Mol Biol. 2017;1515:177-196. |
Characterization of Zebrafish Models of Marinesco-Sjögren Syndrome
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Citation:
PLoS One. 2016 Oct 28;11(10):e0165563. doi: 10.1371/journal.pone.0165563 Epub:
Not Epub Abstract:
SIL1 is a nucleotide exchange factor for the endoplasmic reticulum chaperone, BiP. Mutations in the SIL1 gene cause Marinesco-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kawahara G, Hayashi YK. Characterization of Zebrafish Models of Marinesco-Sjögren Syndrome. PLoS One. 2016 Oct 28;11(10):e0165563. doi: 10.1371/journal.pone.0165563. |
LIM Domain Only 2 Regulates Endothelial Proliferation, Angiogenesis, and Tissue Regeneration
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Citation:
J Am Heart Assoc. 2016 Oct 6;5(10). pii: e004117 Epub:
Not Epub Abstract:
BACKGROUND: LIM domain only 2 (LMO2, human gene) is a key transcription factor that regulates hematopoiesis and vascular... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Meng S, Matrone G, Lv J, Chen K, Wong WT, Cooke JP. LIM Domain Only 2 Regulates Endothelial Proliferation, Angiogenesis, and Tissue Regeneration. J Am Heart Assoc. 2016 Oct 6;5(10). pii: e004117. |
MicroRNA-126a Directs Lymphangiogenesis Through Interacting With Chemokine and Flt4 Signaling in Zebrafish
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Citation:
Arterioscler Thromb Vasc Biol. 2016 Oct 27. pii: ATVBAHA.116.308120. [Epub ahead of print] Epub:
Yes Abstract:
OBJECTIVE: MicroRNA-126 (miR-126) is an endothelium-enriched miRNA and functions in vascular integrity and angiogenesis. The... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen J, Zhu RF, Li FF, Liang YL, Wang C, Qin YW, Huang S, Zhao XX, Jing Q. MicroRNA-126a Directs Lymphangiogenesis Through Interacting With Chemokine and Flt4 Signaling in Zebrafish. Arterioscler Thromb Vasc Biol. 2016 Oct 27. pii: ATVBAHA.116.308120. [Epub ahead of print]. |
Zebrafish embryos as in vivo test tubes to unravel cell-specific mechanisms of neurogenesis during neurodevelopment and in diseases
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Citation:
Neurogenesis (Austin). 2016 Oct 7;3(1):e1232678 Epub:
Not Epub Abstract:
Zebrafish has become a model of choice for developmental studies in particular for studying neural development and related... Organism or Cell Type:
zebrafish Citation Extract: Samarut É. Zebrafish embryos as in vivo test tubes to unravel cell-specific mechanisms of neurogenesis during neurodevelopment and in diseases. Neurogenesis (Austin). 2016 Oct 7;3(1):e1232678. |
Caspase-2 cleavage of tau reversibly impairs memory
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Citation:
Nat Med. 2016 Oct 10. doi: 10.1038/nm.4199 Epub:
Not Epub Abstract:
In Alzheimer's disease (AD) and other tauopathies, the tau protein forms fibrils, which are believed to be neurotoxic.... Delivery Method:
icv infusion Organism or Cell Type:
mice Citation Extract: Zhao X, Kotilinek LA, Smith B, Hlynialuk C, Zahs K, Ramsden M, Cleary J, Ashe KH. Caspase-2 cleavage of tau reversibly impairs memory. Nat Med. 2016 Oct 10. doi: 10.1038/nm.4199. |
Cnbp ameliorates Treacher Collins Syndrome craniofacial anomalies through a pathway that involves redox-responsive genes
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Citation:
Cell Death Dis. 2016 Oct 6;7(10):e2397. doi: 10.1038/cddis.2016.299 Epub:
Not Epub Abstract:
Treacher Collins Syndrome (TCS) is a rare congenital disease (1:50 000 live births) characterized by craniofacial defects,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: de Peralta MS, Mouguelar VS, Sdrigotti MA, Ishiy FA, Fanganiello RD, Passos-Bueno MR, Coux G, Calcaterra NB. Cnbp ameliorates Treacher Collins Syndrome craniofacial anomalies through a pathway that involves redox-responsive genes. Cell Death Dis. 2016 Oct 6;7(10):e2397. doi: 10.1038/cddis.2016.299. |