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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Transcriptional enhancement of Smn levels in motoneurons is crucial for proper axon morphology in zebrafish

Authors:
Spiró Z, Koh A, Tay S, See K, Winkler C
Citation:
Sci Rep. 2016;6:27470. doi:10.1038/srep27470
Epub:
Not Epub
Abstract:
An unresolved mystery in the field of spinal muscular atrophy (SMA) is why a reduction of the ubiquitously expressed Smn...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Spiró Z, Koh A, Tay S, See K, Winkler C. Transcriptional enhancement of Smn levels in motoneurons is crucial for proper axon morphology in zebrafish. Sci Rep. 2016;6:27470. doi:10.1038/srep27470.

Identification of mutations in the MYO9A gene in patients with congenital myasthenic syndrome

Authors:
O'Connor E, Töpf A, Müller JS, Cox D, Evangelista T, Colomer J, Abicht A, Senderek J, Hasselmann O, Yaramis A, Laval SH, Lochmüller H
Citation:
Brain. 2016 Jun 3. pii: aww130. [Epub ahead of print] doi:10.1093/brain/aww130
Epub:
Not Epub
Abstract:
Congenital myasthenic syndromes are a group of rare and genetically heterogenous disorders resulting from defects in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
O'Connor E, Töpf A, Müller JS, Cox D, Evangelista T, Colomer J, Abicht A, Senderek J, Hasselmann O, Yaramis A, Laval SH, Lochmüller H. Identification of mutations in the MYO9A gene in patients with congenital myasthenic syndrome. Brain. 2016 Jun 3. pii: aww130. [Epub ahead of print] doi:10.1093/brain/aww130.

Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts

Authors:
Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz IJ, Pierce EL, Narla A, Seguin A, Hattangadi SM, Medlock AE, Langer NB, Dailey TA, Hurst SN, Faccenda D, Wiwczar JM, Heggers SK, Vogin G, Chen W, Chen C, Campagna DR, Brugnara C, Zhou Y, Ebert BL, Danial NN, Fleming MD, Ward DM, Campanella M, Dailey HA, Kaplan J, Paw BH
Citation:
Nature. 2012 Nov 22;491(7425):608-12. doi: 10.1038/nature11536. Epub 2012 Nov 7. Erratum in: Nature. 2013 Apr 18;496(7445):386
Epub:
Not Epub
Abstract:
Defects in the availability of heme substrates or the catalytic activity of the terminal enzyme in heme biosynthesis,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz IJ, Pierce EL, Narla A, Seguin A, Hattangadi SM, Medlock AE, Langer NB, Dailey TA, Hurst SN, Faccenda D, Wiwczar JM, Heggers SK, Vogin G, Chen W, Chen C, Campagna DR, Brugnara C, Zhou Y, Ebert BL, Danial NN, Fleming MD, Ward DM, Campanella M, Dailey HA, Kaplan J, Paw BH. Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts. Nature. 2012 Nov 22;491(7425):608-12. doi: 10.1038/nature11536. Epub 2012 Nov 7. Erratum in: Nature. 2013 Apr 18;496(7445):386.

Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness

Authors:
Delmaghani S, Aghaie A, Bouyacoub Y, El Hachmi H, Bonnet C, Riahi Z, Chardenoux S, Perfettini I, Hardelin J-P, Houmeida A, Herbomel P, Petit C
Citation:
Am J Hum Genet. 2016;98(6):1266-70. doi:10.1016/j.ajhg.2016.04.015
Epub:
Not Epub
Abstract:
By genetic linkage analysis in a large consanguineous Iranian family with eleven individuals affected by severe to profound...
Organism or Cell Type:
zebrafish
Citation Extract:
Delmaghani S, Aghaie A, Bouyacoub Y, El Hachmi H, Bonnet C, Riahi Z, Chardenoux S, Perfettini I, Hardelin J-P, Houmeida A, Herbomel P, Petit C. Mutations in CDC14A, Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness. Am J Hum Genet. 2016;98(6):1266-70. doi:10.1016/j.ajhg.2016.04.015.

Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis

Authors:
Lin KH, Ho YH, Chiang JC, Li MW, Lin SH, Chen WM, Chiang CL, Lin YN, Yang YJ, Chen CN, Lu J, Huang CJ, Tigyi G, Yao CL, Lee H
Citation:
Sci Rep. 2016 May 31;6:27050. doi: 10.1038/srep27050
Epub:
Not Epub
Abstract:
Lysophosphatidic acid (LPA), a growth factor-like phospholipid, regulates numerous physiological functions, including cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin KH, Ho YH, Chiang JC, Li MW, Lin SH, Chen WM, Chiang CL, Lin YN, Yang YJ, Chen CN, Lu J, Huang CJ, Tigyi G, Yao CL, Lee H. Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis. Sci Rep. 2016 May 31;6:27050. doi: 10.1038/srep27050.

Control of receptor internalization, signaling level, and precise arrival at the target in guided cell migration

Authors:
Minina S, Reichman-Fried M, Raz E
Citation:
Curr Biol. 2007 Jul 3;17(13):1164-72
Epub:
Not Epub
Abstract:
Activation of the chemokine receptor CXCR4 by SDF1 controls a variety of biological processes in development, immune response,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Minina S, Reichman-Fried M, Raz E. Control of receptor internalization, signaling level, and precise arrival at the target in guided cell migration. Curr Biol. 2007 Jul 3;17(13):1164-72.

aPKC regulates apical localization of Lgl to restrict elongation of microridges in developing zebrafish epidermis

Authors:
Raman R, Damle I, Rote R, Banerjee S, Dingare C, Sonawane M
Citation:
Nat Commun. 2016 Jun 1;7:11643. doi: 10.1038/ncomms11643
Epub:
Not Epub
Abstract:
Epithelial cells exhibit apical membrane protrusions, which confer specific functions to epithelial tissues. Microridges are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Raman R, Damle I, Rote R, Banerjee S, Dingare C, Sonawane M. aPKC regulates apical localization of Lgl to restrict elongation of microridges in developing zebrafish epidermis. Nat Commun. 2016 Jun 1;7:11643. doi: 10.1038/ncomms11643.

In vivo confinement promotes collective migration of neural crest cells

Authors:
Szabó A, Melchionda M, Nastasi G, Woods ML, Campo S, Perris R, Mayor R
Citation:
J Cell Biol. 2016 May 30. pii: jcb.201602083. [Epub ahead of print]
Epub:
Yes
Abstract:
Collective cell migration is fundamental throughout development and in many diseases. Spatial confinement using micropatterns...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Szabó A, Melchionda M, Nastasi G, Woods ML, Campo S, Perris R, Mayor R. In vivo confinement promotes collective migration of neural crest cells. J Cell Biol. 2016 May 30. pii: jcb.201602083. [Epub ahead of print].

Early Craniofacial Defects in Zebrafish That Have Reduced Function of a Wnt-Interacting Extracellular Matrix Protein, Tinagl1

Authors:
Neiswender H, Navarre S, Kozlowski DJ, LeMosy EK
Citation:
Cleft Palate Craniofac J. 2016 May 31. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVE: Tinagl1 has a weak genetic association with craniosynostosis, but its functions in cartilage and bone development...
Organism or Cell Type:
zebrafish
Citation Extract:
Neiswender H, Navarre S, Kozlowski DJ, LeMosy EK. Early Craniofacial Defects in Zebrafish That Have Reduced Function of a Wnt-Interacting Extracellular Matrix Protein, Tinagl1. Cleft Palate Craniofac J. 2016 May 31. [Epub ahead of print].

An Elk transcription factor is required for Runx-dependent survival signaling in the sea urchin embryo

Authors:
Rizzo F, Coffman JA, Arnone MI
Citation:
Dev Biol. 2016 May 24. pii: S0012-1606(16)30148-8. doi: 10.1016/j.ydbio.2016.05.026. [Epub ahead of print]
Epub:
Yes
Abstract:
Elk proteins are Ets family transcription factors that regulate cell proliferation, survival, and differentiation in response...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Rizzo F, Coffman JA, Arnone MI. An Elk transcription factor is required for Runx-dependent survival signaling in the sea urchin embryo. Dev Biol. 2016 May 24. pii: S0012-1606(16)30148-8. doi: 10.1016/j.ydbio.2016.05.026. [Epub ahead of print].

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