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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Merlin inhibits Wnt/β-catenin signaling by blocking LRP6 phosphorylation
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Citation:
Cell Death Differ. 2016 Jun 10. doi: 10.1038/cdd.2016.54. [Epub ahead of print] Epub:
Yes Abstract:
Merlin, encoded by the NF2 gene, is a tumor suppressor that acts by inhibiting mitogenic signaling and is mutated in... Citation Extract: Kim M, Kim S, Lee SH, Kim W, Sohn MJ, Kim HS, Kim J, Jho EH. Merlin inhibits Wnt/β-catenin signaling by blocking LRP6 phosphorylation. Cell Death Differ. 2016 Jun 10. doi: 10.1038/cdd.2016.54. [Epub ahead of print]. |
Eph-ephrin signaling maintains the boundary of dorsal forerunner cell cluster during morphogenesis of the zebrafish embryonic left-right organizer
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Citation:
Development. 2016 Jun 10. pii: dev.132969. [Epub ahead of print] Epub:
Not Epub Abstract:
The kupffer's vesicle (KV) is the so-called left-right organizer in teleost fishes. KV is formed from dorsal forerunner... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang JF, Jiang Z, Liu X, Meng A. Eph-ephrin signaling maintains the boundary of dorsal forerunner cell cluster during morphogenesis of the zebrafish embryonic left-right organizer. Development. 2016 Jun 10. pii: dev.132969. [Epub ahead of print]. |
Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy
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Citation:
J Vis Exp. 2016 May 24;(111). doi: 10.3791/53776 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is one of the most common lethal genetic diseases worldwide, caused by mutations in the... Link:
Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Canis familiaris (dog) Citation Extract: Miskew Nichols B, Aoki Y, Kuraoka M, Lee JJ, Takeda S, Yokota T. Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy. J Vis Exp. 2016 May 24;(111). doi: 10.3791/53776. |
Tissue- and stage-specific Wnt target gene expression is controlled subsequent to β-catenin recruitment to cis-regulatory modules
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Citation:
Development. 2016 Jun 1;143(11):1914-25. doi: 10.1242/dev.131664. Epub 2016 Apr 11 Epub:
Not Epub Abstract:
Key signalling pathways, such as canonical Wnt/β-catenin signalling, operate repeatedly to regulate tissue- and stage-specific... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Nakamura Y, de Paiva Alves E, Veenstra GJ, Hoppler S. Tissue- and stage-specific Wnt target gene expression is controlled subsequent to β-catenin recruitment to cis-regulatory modules. Development. 2016 Jun 1;143(11):1914-25. doi: 10.1242/dev.131664. Epub 2016 Apr 11. |
Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration
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Citation:
Biochem J. 2016 Jun 7. pii: BCJ20160388. [Epub ahead of print] Epub:
Yes Abstract:
There is growing evidence that zinc and its transporters are involved in cell migration during development and in cancer. In... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Taylor KM, Muraina I, Brethour D, Schmitt-Ulms G, Nimmanon T, Ziliotto S, Kille P, Hogstrand C. Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration. Biochem J. 2016 Jun 7. pii: BCJ20160388. [Epub ahead of print]. |
Mutation of wrb, a Component of the Guided Entry of Tail-Anchored Protein Pathway, Disrupts Photoreceptor Synapse Structure and Function
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Citation:
Invest Ophthalmol Vis Sci. 2016 Jun 1;57(7):2942-54. doi: 10.1167/iovs.15-18996 Epub:
Not Epub Abstract:
PURPOSE: Tail-anchored (TA) proteins contain a single hydrophobic domain at the C-terminus and are posttranslationally inserted... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Daniele LL, Emran F, Lobo GP, Gaivin RJ, Perkins BD. Mutation of wrb, a Component of the Guided Entry of Tail-Anchored Protein Pathway, Disrupts Photoreceptor Synapse Structure and Function. Invest Ophthalmol Vis Sci. 2016 Jun 1;57(7):2942-54. doi: 10.1167/iovs.15-18996. |
Leptospiral outer membrane protein LipL32 induces inflammation and kidney injury in zebrafish larvae
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Citation:
Sci Rep. 2016;6:27838. doi:10.1038/srep27838 Epub:
Not Epub Abstract:
Leptospirosis is an often overlooked cause of acute kidney injury that can lead to multiple organ failure and even death. The... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chang M-Y, Cheng Y-C, Hsu S-H, Ma T-L, Chou L-F, Hsu H-H, Tian Y-C, Chen Y-C, Sun Y-J, Hung C-C, Pan R-L, Yang C-W. Leptospiral outer membrane protein LipL32 induces inflammation and kidney injury in zebrafish larvae. Sci Rep. 2016;6:27838. doi:10.1038/srep27838. |
An asymptomatic mutation complicating severe chemotherapy-induced peripheral neuropathy (CIPN): a case for personalised medicine and a zebrafish model of CIPN
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Citation:
npj Genomic Med. 2016;1:16016. doi:10.1038/npjgenmed.2016.16 Epub:
Not Epub Abstract:
Targeted next-generation sequencing (NGS) identified a novel loss of function mutation in GARS, a gene linked to Charcot–Marie–... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Holloway MP, DeNardo BD, Phornphutkul C, Nguyen K, Davis C, Jackson C, Richendrfer H, Creton R, Altura RA. An asymptomatic mutation complicating severe chemotherapy-induced peripheral neuropathy (CIPN): a case for personalised medicine and a zebrafish model of CIPN. npj Genomic Med. 2016;1:16016. doi:10.1038/npjgenmed.2016.16. |
LRRK2 knockdown in zebrafish causes developmental defects, neuronal loss, and synuclein aggregation
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Citation:
J Neurosci Res. 2016 Jun 5. doi: 10.1002/jnr.23754. [Epub ahead of print] Epub:
Yes Abstract:
Although mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most common cause of genetic Parkinson's... Organism or Cell Type:
zebrafish Citation Extract: Prabhudesai S, Bensabeur FZ, Abdullah R, Basak I, Baez S, Alves G, Holtzman NG, Larsen JP, Møller SG. LRRK2 knockdown in zebrafish causes developmental defects, neuronal loss, and synuclein aggregation. J Neurosci Res. 2016 Jun 5. doi: 10.1002/jnr.23754. [Epub ahead of print]. |
Unexpected Roles for Ciliary Kinesins and Intraflagellar Transport Proteins
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Citation:
Genetics. 2016 Apr 2. pii: genetics.115.180943. [Epub ahead of print] Epub:
Not Epub Abstract:
Transport of proteins in the ciliary shaft is driven by microtubule-dependent motors, kinesins. Prior studies suggested that... Organism or Cell Type:
zebrafish Citation Extract: Pooranachandran N, Malicki JJ. Unexpected Roles for Ciliary Kinesins and Intraflagellar Transport Proteins. Genetics. 2016 Apr 2. pii: genetics.115.180943. [Epub ahead of print]. |