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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Alternative Splicing of Four Trafficking Genes Regulates Myofiber Structure and Skeletal Muscle Physiology

Authors:
Giudice J, Loehr JA, Rodney GG, Cooper TA
Citation:
Cell Rep. 2016 Nov 15;17(8):1923-1933. doi: 10.1016/j.celrep.2016.10.072
Epub:
Not Epub
Abstract:
During development, transcriptional and post-transcriptional networks are coordinately regulated to drive organ maturation....
Link:
http://www.cell.com/cell-reports/fulltext/S2211-1247(16)31507-8
Delivery Method:
injection then electroporation
Organism or Cell Type:
mouse
Citation Extract:
Giudice J, Loehr JA, Rodney GG, Cooper TA. Alternative Splicing of Four Trafficking Genes Regulates Myofiber Structure and Skeletal Muscle Physiology. Cell Rep. 2016 Nov 15;17(8):1923-1933. doi: 10.1016/j.celrep.2016.10.072.

Glucosylceramide transferase in Giardia preferentially catalyzes the synthesis of galactosylceramide during encystation

Authors:
Robles-Martinez L, Mendez TL, Apodaca J, Das S
Citation:
Mol Biochem Parasitol. 2016 Nov 10. pii: S0166-6851(16)30132-3. doi: 10.1016/j.molbiopara.2016.11.001. [Epub ahead of print]
Epub:
Yes
Abstract:
The stage differentiation from trophozoite to cyst (i.e., encystation) is an essential step for Giardia to survive outside its...
Link:
http://www.sciencedirect.com/science/article/pii/S0166685116301323
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Robles-Martinez L, Mendez TL, Apodaca J, Das S. Glucosylceramide transferase in Giardia preferentially catalyzes the synthesis of galactosylceramide during encystation. Mol Biochem Parasitol. 2016 Nov 10. pii: S0166-6851(16)30132-3. doi: 10.1016/j.molbiopara.2016.11.001. [Epub ahead of print].

Genetic and pharmacological inhibition of CDK9 drives neutrophil apoptosis to resolve inflammation in zebrafish in vivo

Authors:
Hoodless LJ, Lucas CD, Duffin R, Denvir MA, Haslett C, Tucker CS, Rossi AG
Citation:
Sci Rep. 2016 Nov 11;5:36980. doi: 10.1038/srep36980
Epub:
Not Epub
Abstract:
Neutrophilic inflammation is tightly regulated and subsequently resolves to limit tissue damage and promote repair. When the...
Link:
http://www.nature.com/articles/srep36980
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hoodless LJ, Lucas CD, Duffin R, Denvir MA, Haslett C, Tucker CS, Rossi AG. Genetic and pharmacological inhibition of CDK9 drives neutrophil apoptosis to resolve inflammation in zebrafish in vivo. Sci Rep. 2016 Nov 11;5:36980. doi: 10.1038/srep36980.

miRNA-487a Promotes Proliferation and Metastasis in Hepatocellular Carcinoma

Authors:
Chang RM, Xiao S, Lei X, Yang H, Fang F, Yang LY
Citation:
Clin Cancer Res. 2017:[Epub ahead of print] doi:10.1158/1078-0432.CCR-16-0851
Epub:
Yes
Abstract:
PURPOSE: Hepatocellular carcinoma (HCC) harbors highly metastatic properties, accounting for postoperative recurrence and...
Link:
http://clincancerres.aacrjournals.org/content/23/10/2593
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse
Citation Extract:
Chang RM, Xiao S, Lei X, Yang H, Fang F, Yang LY. miRNA-487a Promotes Proliferation and Metastasis in Hepatocellular Carcinoma. Clin Cancer Res. 2017:[Epub ahead of print] doi:10.1158/1078-0432.CCR-16-0851.

Copy number variation as a genetic basis for heterotaxy and heterotaxy-spectrum congenital heart defects

Authors:
Cowan JR, Tariq M, Shaw C, Rao M, Belmont JW, Lalani SR, Smolarek TA, Ware SM
Citation:
Philos Trans R Soc Lond B Biol Sci. 2016 Dec 19;371(1710). pii: 20150406
Epub:
Not Epub
Abstract:
Genomic disorders and rare copy number abnormalities are identified in 15-25% of patients with syndromic conditions, but their...
Link:
http://rstb.royalsocietypublishing.org/content/371/1710/20150406.long
Organism or Cell Type:
Xenopus
Citation Extract:
Cowan JR, Tariq M, Shaw C, Rao M, Belmont JW, Lalani SR, Smolarek TA, Ware SM. Copy number variation as a genetic basis for heterotaxy and heterotaxy-spectrum congenital heart defects. Philos Trans R Soc Lond B Biol Sci. 2016 Dec 19;371(1710). pii: 20150406.

Retinoic acid catabolizing enzyme CYP26C1 is a genetic modifier in SHOX deficiency

Authors:
Montalbano A, Juergensen L, Roeth R, Weiss B, Fukami M, Fricke‐Otto S, Binder G, Ogata T, Decker E, Nuernberg G, Hassel D, Rappold GA
Citation:
EMBO Molec Med. 2016;[Epub] doi:10.15252/emmm.201606623
Epub:
Yes
Abstract:
Mutations in the homeobox gene SHOX cause SHOX deficiency, a condition with clinical manifestations ranging from short stature...
Link:
http://embomolmed.embopress.org/content/early/2016/11/14/emmm.201606623
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Montalbano A, Juergensen L, Roeth R, Weiss B, Fukami M, Fricke‐Otto S, Binder G, Ogata T, Decker E, Nuernberg G, Hassel D, Rappold GA. Retinoic acid catabolizing enzyme CYP26C1 is a genetic modifier in SHOX deficiency. EMBO Molec Med. 2016;[Epub] doi:10.15252/emmm.201606623.

EphrinB1/EphB3b Coordinate Bidirectional Epithelial-Mesenchymal Interactions Controlling Liver Morphogenesis and Laterality

Authors:
Cayuso J, Dzementsei A, Fischer JC, Karemore G, Caviglia S, Bartholdson J, Wright GJ, Ober EA
Citation:
Dev Cell. 2016;39(3):316-28. doi:10.1016/j.devcel.2016.10.009
Epub:
Not Epub
Abstract:
Positioning organs in the body often requires the movement of multiple tissues, yet the molecular and cellular mechanisms...
Link:
http://www.cell.com/developmental-cell/abstract/S1534-5807(16)30722-5
Organism or Cell Type:
zebrafish
Citation Extract:
Cayuso J, Dzementsei A, Fischer JC, Karemore G, Caviglia S, Bartholdson J, Wright GJ, Ober EA. EphrinB1/EphB3b Coordinate Bidirectional Epithelial-Mesenchymal Interactions Controlling Liver Morphogenesis and Laterality. Dev Cell. 2016;39(3):316-28. doi:10.1016/j.devcel.2016.10.009.

Identification of novel MYO18A interaction partners required for myoblast adhesion and muscle integrity

Authors:
Cao J-M, Cheng X-N, Shang-Qi Li, Heller S, Xu Z-G, Shi D-L
Citation:
Sci Rep. 2016;6:36768. doi:10.1038/srep36768
Epub:
Not Epub
Abstract:
The unconventional myosin MYO18A that contains a PDZ domain is required for muscle integrity during zebrafish development....
Link:
http://www.nature.com/articles/srep36768
Citation Extract:
Cao J-M, Cheng X-N, Shang-Qi Li, Heller S, Xu Z-G, Shi D-L. Identification of novel MYO18A interaction partners required for myoblast adhesion and muscle integrity. Sci Rep. 2016;6:36768. doi:10.1038/srep36768.

Stathmin-like 4 is critical for the maintenance of neural progenitor cells in dorsal midbrain of zebrafish larvae

Authors:
Lin MJ, Lee SJ
Citation:
Sci Rep. 2016 Nov 7;6:36188. doi: 10.1038/srep36188
Epub:
Not Epub
Abstract:
A delicate balance between proliferating and differentiating signals is necessary to ensure proper growth and neuronal...
Link:
http://www.nature.com/articles/srep36188
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin MJ, Lee SJ. Stathmin-like 4 is critical for the maintenance of neural progenitor cells in dorsal midbrain of zebrafish larvae. Sci Rep. 2016 Nov 7;6:36188. doi: 10.1038/srep36188.

Spemann organizer gene Goosecoid promotes delamination of neuroblasts from the otic vesicle

Authors:
Kantarci H, Gerberding A, Riley BB
Citation:
Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6840-E6848
Epub:
Not Epub
Abstract:
Neurons of the Statoacoustic Ganglion (SAG), which innervate the inner ear, originate as neuroblasts in the floor of the otic...
Link:
http://www.pnas.org/content/113/44/E6840.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kantarci H, Gerberding A, Riley BB. Spemann organizer gene Goosecoid promotes delamination of neuroblasts from the otic vesicle. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6840-E6848.

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