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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Addressing the functional determinants of FAK during ciliogenesis in multiciliated cells

Authors:
Antoniades I, Stylianou P, Christodoulou N, Skourides PA
Citation:
J Biol Chem. 2016 Nov 28. pii: jbc.M116.767111. [Epub ahead of print]
Epub:
Yes
Abstract:
We have previously identified FAK as an important regulator of ciliogenesis in multiciliated cells. FAK and other focal...
Link:
http://www.jbc.org/content/early/2016/11/28/jbc.M116.767111.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Antoniades I, Stylianou P, Christodoulou N, Skourides PA. Addressing the functional determinants of FAK during ciliogenesis in multiciliated cells. J Biol Chem. 2016 Nov 28. pii: jbc.M116.767111. [Epub ahead of print].

Neuronal Ndrg4 Is Essential for Nodes of Ranvier Organization in Zebrafish

Authors:
Fontenas L, De Santis F, Di Donato V, Degerny C, Chambraud B, Del Bene F, Tawk M
Citation:
PLoS Genet. 2016;12(11):e1006459. doi:10.1371/journal.pgen.1006459
Epub:
Not Epub
Abstract:
Axon ensheathment by specialized glial cells is an important process for fast propagation of action potentials. The rapid...
Link:
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1006459
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fontenas L, De Santis F, Di Donato V, Degerny C, Chambraud B, Del Bene F, Tawk M. Neuronal Ndrg4 Is Essential for Nodes of Ranvier Organization in Zebrafish. PLoS Genet. 2016;12(11):e1006459. doi:10.1371/journal.pgen.1006459.

Stag3 regulates microtubule stability to maintain euploidy during mouse oocyte meiotic maturation

Authors:
Zhang M, Dai X, Sun Y, Lu Y, Zhou C, Miao Y, Wang Y, Xiong B
Citation:
Oncotarget. 2016 Nov 29. doi: 10.18632/oncotarget.13684. [Epub ahead of print]
Epub:
Yes
Abstract:
Stag3, a meiosis-specific subunit of cohesin complex, has been demonstrated to function in both male and female reproductive...
Link:
https://www.oncotarget.com/article/13684/
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Zhang M, Dai X, Sun Y, Lu Y, Zhou C, Miao Y, Wang Y, Xiong B. Stag3 regulates microtubule stability to maintain euploidy during mouse oocyte meiotic maturation. Oncotarget. 2016 Nov 29. doi: 10.18632/oncotarget.13684. [Epub ahead of print].

MDM2 prevents spontaneous tubular epithelial cell death and acute kidney injury

Authors:
Thomasova D, Ebrahim M, Fleckinger K, Li M, Molnar J, Popper B, Liapis H, Kotb AM, Siegerist F, Endlich N, Anders HJ
Citation:
Cell Death Dis. 2016 Nov 24;7(11):e2482. doi: 10.1038/cddis.2016.390
Epub:
Not Epub
Abstract:
Murine double minute-2 (MDM2) is an E3-ubiquitin ligase and the main negative regulator of tumor suppressor gene p53. MDM2 has...
Link:
http://www.nature.com/cddis/journal/v7/n11/full/cddis2016390a.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thomasova D, Ebrahim M, Fleckinger K, Li M, Molnar J, Popper B, Liapis H, Kotb AM, Siegerist F, Endlich N, Anders HJ. MDM2 prevents spontaneous tubular epithelial cell death and acute kidney injury. Cell Death Dis. 2016 Nov 24;7(11):e2482. doi: 10.1038/cddis.2016.390.

Tfap2 and Sox1/2/3 cooperatively specify ectodermal fates in ascidian embryos

Authors:
Imai KS, Hikawa H, Kobayashi K, Satou Y
Citation:
Development. 2016 Nov 25. pii: dev.142109. [Epub ahead of print]
Epub:
Yes
Abstract:
Epidermis and neural tissues differentiate from the ectoderm in animal embryos. While epidermal fate is thought to be induced...
Link:
http://dev.biologists.org/content/early/2016/11/24/dev.142109.long
Delivery Method:
microinjection
Organism or Cell Type:
Ciona (ascidian)
Citation Extract:
Imai KS, Hikawa H, Kobayashi K, Satou Y. Tfap2 and Sox1/2/3 cooperatively specify ectodermal fates in ascidian embryos. Development. 2016 Nov 25. pii: dev.142109. [Epub ahead of print].

Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis

Authors:
Mueller AA, van Velthoven CT, Fukumoto KD, Cheung TH, Rando TA
Citation:
Nature. 2016 Nov 28. doi: 10.1038/nature20160. [Epub ahead of print]
Epub:
Yes
Abstract:
Platelet-derived growth factor receptor α (PDGFRα) exhibits divergent effects in skeletal muscle. At physiological levels,...
Link:
https://www.nature.com/articles/nature20160
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Mueller AA, van Velthoven CT, Fukumoto KD, Cheung TH, Rando TA. Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis. Nature. 2016 Nov 28. doi: 10.1038/nature20160. [Epub ahead of print].

Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle

Authors:
Taglietti V, Maroli G, Cermenati S, Monteverde S, Ferrante A, Rossi G, Cossu G, Beltrame M, Messina G
Citation:
Cell Rep. 2016 Nov 22;17(9):2354-2366. doi: 10.1016/j.celrep.2016.10.082
Epub:
Not Epub
Abstract:
Sox6 belongs to the Sox gene family and plays a pivotal role in fiber type differentiation, suppressing transcription of slow-...
Link:
http://www.cell.com/cell-reports/abstract/S2211-1247(16)31517-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Taglietti V, Maroli G, Cermenati S, Monteverde S, Ferrante A, Rossi G, Cossu G, Beltrame M, Messina G. Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle. Cell Rep. 2016 Nov 22;17(9):2354-2366. doi: 10.1016/j.celrep.2016.10.082.

Injections of Predatory Bacteria Work Alongside Host Immune Cells to Treat Shigella Infection in Zebrafish Larvae

Authors:
Willis AR, Moore C, Mazon-Moya M, Krokowski S, Lambert C, Till R, Mostowy S, Sockett RE
Citation:
Curr Biol. 2016 Nov 22. pii: S0960-9822(16)31152-6. doi: 10.1016/j.cub.2016.09.067. [Epub ahead of print]
Epub:
Yes
Abstract:
Bdellovibrio bacteriovorus are predatory bacteria that invade and kill a range of Gram-negative bacterial pathogens in natural...
Link:
http://www.cell.com/current-biology/fulltext/S0960-9822(16)31152-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Willis AR, Moore C, Mazon-Moya M, Krokowski S, Lambert C, Till R, Mostowy S, Sockett RE. Injections of Predatory Bacteria Work Alongside Host Immune Cells to Treat Shigella Infection in Zebrafish Larvae. Curr Biol. 2016 Nov 22. pii: S0960-9822(16)31152-6. doi: 10.1016/j.cub.2016.09.067. [Epub ahead of print].

PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis

Authors:
Mana G, Clapero F, Panieri E, Panero V, Böttcher RT, Tseng HY, Saltarin F, Astanina E, Wolanska KI, Morgan MR, Humphries MJ, Santoro MM, Serini G, Valdembri D
Citation:
Nat Commun. 2016 Nov 23;7:13546. doi: 10.1038/ncomms13546
Epub:
Not Epub
Abstract:
Basolateral polymerization of cellular fibronectin (FN) into a meshwork drives endothelial cell (EC) polarity and vascular...
Link:
http://www.nature.com/articles/ncomms13546
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mana G, Clapero F, Panieri E, Panero V, Böttcher RT, Tseng HY, Saltarin F, Astanina E, Wolanska KI, Morgan MR, Humphries MJ, Santoro MM, Serini G, Valdembri D. PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis. Nat Commun. 2016 Nov 23;7:13546. doi: 10.1038/ncomms13546.

Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis

Authors:
Kim W, Khan SK, Gvozdenovic-Jeremic J, Kim Y, Dahlman J, Kim H, Park O, Ishitani T, Jho EH, Gao B, Yang Y
Citation:
J Clin Invest. 2016 Nov 21. pii: 88486. doi: 10.1172/JCI88486. [Epub ahead of print]
Epub:
Yes
Abstract:
Malignant tumors develop through multiple steps of initiation and progression, and tumor initiation is of singular importance...
Link:
https://www.jci.org/articles/view/88486
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim W, Khan SK, Gvozdenovic-Jeremic J, Kim Y, Dahlman J, Kim H, Park O, Ishitani T, Jho EH, Gao B, Yang Y. Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis. J Clin Invest. 2016 Nov 21. pii: 88486. doi: 10.1172/JCI88486. [Epub ahead of print].

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