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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Investigating Synthetic Oligonucleotide Targeting of Mir31 in Duchenne Muscular Dystrophy
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Citation:
PLoS Curr. 2016 Jun 16;8. pii: ecurrents.md.99d88e72634387639707601b237467d7. doi: 10.1371/currents.md.99d88e72634387639707601b237467d7 Epub:
Not Epub Abstract:
Exon-skipping via synthetic antisense oligonucleotides represents one of the most promising potential therapies for Duchenne... Delivery Method:
electroporation, cell bathing, Vivo-Morpholino Organism or Cell Type:
cell culture: H2KSF1 (derived from an mdx-immortomouse cross), mdx mice Citation Extract: Hildyard JC, Wells DJ. Investigating Synthetic Oligonucleotide Targeting of Mir31 in Duchenne Muscular Dystrophy. PLoS Curr. 2016 Jun 16;8. pii: ecurrents.md.99d88e72634387639707601b237467d7. doi: 10.1371/currents.md.99d88e72634387639707601b237467d7. |
HER2-positive breast cancer targeting and treatment by a peptide-conjugated mini nanodrug
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Citation:
Nanomedicine. 2016 Aug 9. pii: S1549-9634(16)30103-4. doi: 10.1016/j.nano.2016.07.013. [Epub ahead of print] Epub:
Yes Abstract:
HER2+ breast cancer is one of the most aggressive forms of breast cancer. The new polymalic acid-based mini nanodrug copolymers... Delivery Method:
nanoparticle Organism or Cell Type:
cell culture: BT474 human breast cancer, MDA-MB-468, mice Citation Extract: Ding H, Gangalum PR, Galstyan A, Fox I, Patil R, Hubbard P, Murali R, Ljubimova JY, Holler E. HER2-positive breast cancer targeting and treatment by a peptide-conjugated mini nanodrug. Nanomedicine. 2016 Aug 9. pii: S1549-9634(16)30103-4. doi: 10.1016/j.nano.2016.07.013. [Epub ahead of print]. |
Vitamin D receptor deficiency impairs inner ear development in zebrafish
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Citation:
Biochem Biophys Res Commun. 2016 Aug 12. pii: S0006-291X(16)31325-0. doi: 10.1016/j.bbrc.2016.08.070. [Epub ahead of print] Epub:
Yes Abstract:
The biological actions of vitamin D are largely mediated through binding to the vitamin D receptor (VDR), a member of the... Organism or Cell Type:
zebrafish Citation Extract: Kwon HJ. Vitamin D receptor deficiency impairs inner ear development in zebrafish. Biochem Biophys Res Commun. 2016 Aug 12. pii: S0006-291X(16)31325-0. doi: 10.1016/j.bbrc.2016.08.070. [Epub ahead of print]. |
Zebrafish P54 RNA helicases are cytoplasmic granules residents that are required for development and stress resilience
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Citation:
Biol Open. 2016 Aug 3. pii: bio.015826. doi: 10.1242/bio.015826. [Epub ahead of print] Epub:
Yes Abstract:
Stress granules are cytoplasmic foci that directly respond to the protein synthesis status of the cell. Various environmental... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zampedri C, Tinoco-Cuellar M, Carrillo-Rosas S, Diaz-Tellez A, Ramos-Balderas JL, Pelegri F, Maldonado E. Zebrafish P54 RNA helicases are cytoplasmic granules residents that are required for development and stress resilience. Biol Open. 2016 Aug 3. pii: bio.015826. doi: 10.1242/bio.015826. [Epub ahead of print]. |
Wtip is required for proepicardial organ specification and cardiac left/right asymmetry in zebrafish
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Citation:
Mol Med Rep. 2016 Sep;14(3):2665-78. doi: 10.3892/mmr.2016.5550. Epub 2016 Jul 27 Epub:
Not Epub Abstract:
Wilm's tumor 1 interacting protein (Wtip) was identified as an interacting partner of Wilm's tumor protein (WT1) in a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Powell R, Bubenshchikova E, Fukuyo Y, Hsu C, Lakiza O, Nomura H, Renfrew E, Garrity D, Obara T. Wtip is required for proepicardial organ specification and cardiac left/right asymmetry in zebrafish. Mol Med Rep. 2016 Sep;14(3):2665-78. doi: 10.3892/mmr.2016.5550. Epub 2016 Jul 27. |
Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway
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Citation:
J Biomed Sci. 2016 Aug 2;23(1):59. doi: 10.1186/s12929-016-0277-9 Epub:
Not Epub Abstract:
BACKGROUND: Development of neural and vascular systems displays astonishing similarities among vertebrates. This parallelism is... Organism or Cell Type:
zebrafish Citation Extract: Liu LY, Lin MH, Lai ZY, Jiang JP, Huang YC, Jao LE, Chuang YJ. Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway. J Biomed Sci. 2016 Aug 2;23(1):59. doi: 10.1186/s12929-016-0277-9. |
An amphipathic trans-acting phosphorothioate DNA element delivers uncharged PNA and PMO nucleic acid sequences in mammalian cells
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Citation:
Curr Protoc Nucleic Acid Chem. 2016;64:4.69.1-4.69.22. Epub 2016 Mar 1 Epub:
Not Epub Abstract:
An innovative approach to the delivery of uncharged peptide nucleic acids (PNAs) and phosphorodiamidate morpholino (PMO)... Organism or Cell Type:
cell culture: HeLa pLuc705 Citation Extract: Jain HV, Beaucage SL. An amphipathic trans-acting phosphorothioate DNA element delivers uncharged PNA and PMO nucleic acid sequences in mammalian cells. Curr Protoc Nucleic Acid Chem. 2016;64:4.69.1-4.69.22. Epub 2016 Mar 1. |
[OP.4D.01] Functional Analysis of Tmem63c in Zebrafish Reveals Its Role as a Novel Candidate for Albuminuria and Chronic Kidney Disease
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Citation:
J Hypertens. 2016 Sep;34 Suppl 2:e51. doi: 10.1097/01.hjh.0000491467.44896.76 Epub:
Not Epub Abstract:
OBJECTIVE: The Munich Wistar Frömter (MWF) rat represents a rat model for chronic kidney disease (CKD) with the development of... Organism or Cell Type:
zebrafish Citation Extract: Kreutz R, Schulz A, Meyer AM, Lorenzen T, Stoll M, Panakova D. [OP.4D.01] Functional Analysis of Tmem63c in Zebrafish Reveals Its Role as a Novel Candidate for Albuminuria and Chronic Kidney Disease. J Hypertens. 2016 Sep;34 Suppl 2:e51. doi: 10.1097/01.hjh.0000491467.44896.76. |
Fragile X mental retardation protein knockdown in the developing Xenopus tadpole optic tectum results in enhanced feedforward inhibition and behavioral deficits
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Citation:
Neural Dev. 2016 Aug 8;11(1):14. doi: 10.1186/s13064-016-0069-7 Epub:
Not Epub Abstract:
BACKGROUND: Fragile X Syndrome is the leading monogenetic cause of autism and most common form of intellectual disability.... Delivery Method:
brain injection then electroporation Organism or Cell Type:
Xenopus laevis Citation Extract: Truszkowski TL, James EJ, Hasan M, Wishard TJ, Liu Z, Pratt KG, Cline HT, Aizenman CD. Fragile X mental retardation protein knockdown in the developing Xenopus tadpole optic tectum results in enhanced feedforward inhibition and behavioral deficits. Neural Dev. 2016 Aug 8;11(1):14. doi: 10.1186/s13064-016-0069-7. |
Fis1 depletion in osteoarthritis impairs chondrocyte survival and peroxisomal and lysosomal function
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Citation:
J Mol Med (Berl). 2016 Aug 6. [Epub ahead of print] Epub:
Yes Abstract:
Cumulative evidence suggests the importance of organelle homeostasis in regulating metabolic functions in response to various... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kim D, Song J, Kang Y, Park S, Kim YI, Kwak S, Lim D, Park R, Chun CH, Choe SK, Jin EJ. Fis1 depletion in osteoarthritis impairs chondrocyte survival and peroxisomal and lysosomal function. J Mol Med (Berl). 2016 Aug 6. [Epub ahead of print]. |