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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Loss of mtch2 function impairs early development of liver, intestine and visceral adipocytes in zebrafish larvae

Authors:
Landgraf K, Strobach A, Kiess W, Körner A
Citation:
FEBS Lett. 2016 Jul 28. doi: 10.1002/1873-3468.12330. [Epub ahead of print]
Epub:
Yes
Abstract:
The mitochondrial carrier homolog 2 (MTCH2) has been shown to be essential for embryogenesis in mice, and variants in the MTCH2...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/1873-3468.12330/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Landgraf K, Strobach A, Kiess W, Körner A. Loss of mtch2 function impairs early development of liver, intestine and visceral adipocytes in zebrafish larvae. FEBS Lett. 2016 Jul 28. doi: 10.1002/1873-3468.12330. [Epub ahead of print].

Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1

Authors:
Fraszczak J, Helness A, Chen R, Vadnais C, Robert F, Khandanpour C, Möröy T
Citation:
PLoS One. 2016;11(7):e0160344. doi:10.1371/journal.pone.0160344
Epub:
Not Epub
Abstract:
A regulatory circuit that controls myeloid versus B lymphoid cell fate in hematopoietic progenitors has been proposed, in which...
Link:
http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0160344
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: LSK cells (B cell progenitors)
Citation Extract:
Fraszczak J, Helness A, Chen R, Vadnais C, Robert F, Khandanpour C, Möröy T. Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1. PLoS One. 2016;11(7):e0160344. doi:10.1371/journal.pone.0160344.

Dynamic phosphorylation of Histone Deacetylase 1 by Aurora kinases during mitosis regulates zebrafish embryos development

Authors:
Loponte S, Segré CV, Senese S, Miccolo C, Santaguida S, Deflorian G, Citro S, Mattoscio D, Pisati F, Moser MA, Visintin R, Seiser C, Chiocca S
Citation:
Sci Rep. 2016;6:30213. doi:10.1038/srep30213
Epub:
Not Epub
Abstract:
Histone deacetylases (HDACs) catalyze the removal of acetyl molecules from histone and non-histone substrates playing important...
Link:
http://www.nature.com/articles/srep30213
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Loponte S, Segré CV, Senese S, Miccolo C, Santaguida S, Deflorian G, Citro S, Mattoscio D, Pisati F, Moser MA, Visintin R, Seiser C, Chiocca S. Dynamic phosphorylation of Histone Deacetylase 1 by Aurora kinases during mitosis regulates zebrafish embryos development. Sci Rep. 2016;6:30213. doi:10.1038/srep30213.

Plexins function in epithelial repair in both Drosophila and zebrafish

Authors:
Yoo SK, Pascoe HG, Pereira T, Kondo S, Jacinto A, Zhang X, Hariharan IK
Citation:
Nat Comm. 2016;7:12282. doi:10.1038/ncomms12282
Epub:
Not Epub
Abstract:
In most multicellular organisms, homeostasis is contingent upon maintaining epithelial integrity. When unanticipated insults...
Link:
http://www.nature.com/ncomms/2016/160725/ncomms12282/full/ncomms12282.html#abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yoo SK, Pascoe HG, Pereira T, Kondo S, Jacinto A, Zhang X, Hariharan IK. Plexins function in epithelial repair in both Drosophila and zebrafish. Nat Comm. 2016;7:12282. doi:10.1038/ncomms12282.

Combretastatin A-4 efficiently inhibits angiogenesis and induces neuronal apoptosis in zebrafish

Authors:
Shi Y-W, Yuan W, Wang X, Gong J, Zhu S-X, Chai L-L, Qi J-L, Qin Y-Y,Gao Y,Zhou Y-L, Fan X-L, Ji C-Y, Wu J-Y, Wang Z-W, Liu D
Citation:
Sci Rep. 2016;6:30189. doi:10.1038/srep30189
Epub:
Not Epub
Abstract:
Cis-stilbene combretastatin A-4 (CA-4) and a large group of its derivant compounds have been shown significant anti-...
Link:
http://www.nature.com/articles/srep30189#abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shi Y-W, Yuan W, Wang X, Gong J, Zhu S-X, Chai L-L, Qi J-L, Qin Y-Y,Gao Y,Zhou Y-L, Fan X-L, Ji C-Y, Wu J-Y, Wang Z-W, Liu D. Combretastatin A-4 efficiently inhibits angiogenesis and induces neuronal apoptosis in zebrafish. Sci Rep. 2016;6:30189. doi:10.1038/srep30189.

Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry

Authors:
Takeuchi JK, Lickert H, Bisgrove BW, Sun X, Yamamoto M, Chawengsaksophak K, Hamada H, Yost HJ, Rossant J, Bruneau BG
Citation:
Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):846-51. Epub 2007 Jan 8
Epub:
Not Epub
Abstract:
Notch-mediated induction of Nodal at the vertebrate node is a critical step in initiating left-right (LR) asymmetry. In mice...
Link:
http://www.pnas.org/content/104/3/846.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Takeuchi JK, Lickert H, Bisgrove BW, Sun X, Yamamoto M, Chawengsaksophak K, Hamada H, Yost HJ, Rossant J, Bruneau BG. Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry. Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):846-51. Epub 2007 Jan 8.

cMyb acts in parallel and cooperatively with Cebp1 to regulate neutrophil maturation in zebrafish

Authors:
Jin H, Huang Z, Chi Y, Wu M, Zhou R, Zhao L, Xu J, Zhen F, Lan Y, Li L, Zhang W, Wen Z, Zhang Y
Citation:
Blood. 2016 Jun 6. pii: blood-2015-12-686147. [Epub ahead of print]
Epub:
Yes
Abstract:
Neutrophils are the key effectors for generating innate immunity in response to pathogenic infection and tissue injury in...
Link:
http://www.bloodjournal.org/content/128/3/415
Organism or Cell Type:
zebrafish
Citation Extract:
Jin H, Huang Z, Chi Y, Wu M, Zhou R, Zhao L, Xu J, Zhen F, Lan Y, Li L, Zhang W, Wen Z, Zhang Y. cMyb acts in parallel and cooperatively with Cebp1 to regulate neutrophil maturation in zebrafish. Blood. 2016 Jun 6. pii: blood-2015-12-686147. [Epub ahead of print].

Cholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling

Authors:
Mathews ES, Appel B
Citation:
J Neurosci. 2016;36(29):7628-39. doi:10.1523/JNEUROSCI.0726-16.2016
Epub:
Not Epub
Abstract:
Myelin, which ensheaths and insulates axons, is a specialized membrane highly enriched with cholesterol. During myelin...
Link:
http://www.jneurosci.org/content/36/29/7628.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mathews ES, Appel B. Cholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling. J Neurosci. 2016;36(29):7628-39. doi:10.1523/JNEUROSCI.0726-16.2016.

RNA- binding protein Stau2 is important for spindle integrity and meiosis progression in mouse oocytes

Authors:
Cao Y, Du J, Chen D, Wang Q, Zhang N, Liu X, Liu X, Weng J, Liang Y, Ma W
Citation:
Cell Cycle. 2016 Jul 19:0. [Epub ahead of print]
Epub:
Yes
Abstract:
Staufen2 (Stau2) is a double-stranded RNA-binding protein involved in cell fate decision by regulating mRNA transport, mRNA...
Link:
http://www.tandfonline.com/doi/abs/10.1080/15384101.2016.1208869
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Cao Y, Du J, Chen D, Wang Q, Zhang N, Liu X, Liu X, Weng J, Liang Y, Ma W. RNA- binding protein Stau2 is important for spindle integrity and meiosis progression in mouse oocytes. Cell Cycle. 2016 Jul 19:0. [Epub ahead of print].

A gene trap transposon eliminates haematopoietic expression of zebrafish Gfi1aa, but does not interfere with haematopoiesis

Authors:
Thambyrajah R, Ucanok D, Jalali M, Hough Y, Wilkinson RN, McMahon K, Moore C, Gering M
Citation:
Dev Biol. 2016 Jul 15. pii: S0012-1606(16)30160-9. doi: 10.1016/j.ydbio.2016.07.010. [Epub ahead of print]
Epub:
Yes
Abstract:
A transposon-mediated gene trap screen identified the zebrafish line qmc551 that expresses a GFP reporter in primitive...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616301609
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thambyrajah R, Ucanok D, Jalali M, Hough Y, Wilkinson RN, McMahon K, Moore C, Gering M. A gene trap transposon eliminates haematopoietic expression of zebrafish Gfi1aa, but does not interfere with haematopoiesis. Dev Biol. 2016 Jul 15. pii: S0012-1606(16)30160-9. doi: 10.1016/j.ydbio.2016.07.010. [Epub ahead of print].

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