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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing

Authors:
Zhang Y, O’Leary MN, Peri S, Wang M, Zha J, Melov S, Kappes DJ, Feng Q, Rhodes J, Amieux PS, Morris DR, Kennedy BK, Wiest DL
Citation:
Cell Rep. 2017;18:545-556. doi:10.1016/j.celrep.2016.12.034
Epub:
Not Epub
Abstract:
Most ribosomal proteins (RP) are regarded as essential, static components that contribute only to ribosome biogenesis and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, O’Leary MN, Peri S, Wang M, Zha J, Melov S, Kappes DJ, Feng Q, Rhodes J, Amieux PS, Morris DR, Kennedy BK, Wiest DL. Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing. Cell Rep. 2017;18:545-556. doi:10.1016/j.celrep.2016.12.034.

SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome

Authors:
Shaw ND, Brand H, Kupchinsky ZA, Bengani H, Plummer L, Jones TI, Erdin S, Williamson KA, Rainger J, Stortchevoi A, Samocha K, Currall BB, Dunican DS, Collins RL, Willer JR, Lek A, Lek M, Nassan M, Pereira S, Kammin T, Lucente D, Silva A, Seabra CM, Chiang C, An Y, Ansari M, Rainger JK, Joss S, Smith JC, <authors removed - database limit>, Schimmenti LA, Brasseur B, Cesaretti C, García-Ortiz JE, Buitrago TP, Silva OP, Hoffman JD, Mühlbauer W, Ruprecht KW, Loeys BL, Shino M, Kaindl AM, Cho CH, Morton CC, Meehan RR, van Heyningen V, Liao EC, Balasubramanian R, Hall JE, Seminara SB, Macarthur D, Moore SA, Yoshiura KI, Gusella JF, Marsh JA, Graham JM Jr, Lin AE, Katsanis N, Jones PL, Crowley WF Jr, Davis EE, FitzPatrick DR, Talkowski ME
Citation:
Nat Genet. 2017 Jan 9. doi: 10.1038/ng.3743. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Arhinia, or absence of the nose, is a rare malformation of unknown etiology that is often accompanied by ocular and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shaw ND, Brand H, Kupchinsky ZA, Bengani H, Plummer L, Jones TI, Erdin S, Williamson KA, Rainger J, Stortchevoi A, Samocha K, Currall BB, Dunican DS, Collins RL, Willer JR, Lek A, Lek M, Nassan M, Pereira S, Kammin T, Lucente D, Silva A, Seabra CM, Chiang C, An Y, Ansari M, Rainger JK, Joss S, Smith JC, <authors removed - database limit>, Schimmenti LA, Brasseur B, Cesaretti C, García-Ortiz JE, Buitrago TP, Silva OP, Hoffman JD, Mühlbauer W, Ruprecht KW, Loeys BL, Shino M, Kaindl AM, Cho CH, Morton CC, Meehan RR, van Heyningen V, Liao EC, Balasubramanian R, Hall JE, Seminara SB, Macarthur D, Moore SA, Yoshiura KI, Gusella JF, Marsh JA, Graham JM Jr, Lin AE, Katsanis N, Jones PL, Crowley WF Jr, Davis EE, FitzPatrick DR, Talkowski ME. SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome. Nat Genet. 2017 Jan 9. doi: 10.1038/ng.3743. [Epub ahead of print].

Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization

Authors:
Wild R, Klems A, Takamiya M0, Hayashi Y, Strähle U, Ando K, Mochizuki N, van Impel A, Schulte-Merker S, Krueger J, Preau L, le Noble F
Citation:
Nat Comm. 2017;8:13991. doi:10.1038/ncomms13991
Epub:
Not Epub
Abstract:
Formation of organ-specific vasculatures requires cross-talk between developing tissue and specialized endothelial cells. Here...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wild R, Klems A, Takamiya M0, Hayashi Y, Strähle U, Ando K, Mochizuki N, van Impel A, Schulte-Merker S, Krueger J, Preau L, le Noble F. Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization. Nat Comm. 2017;8:13991. doi:10.1038/ncomms13991.

The larvicide pyriproxyfen blamed during the Zika virus outbreak does not cause microcephaly in zebrafish embryos

Authors:
Dzieciolowska S, Larroque AL, Kranjec EA, Drapeau P, Samarut E
Citation:
Sci Rep. 2017 Jan 4;7:40067. doi: 10.1038/srep40067
Epub:
Not Epub
Abstract:
Although the zika virus (ZIKV) has now been strongly correlated with emerging cases of microcephaly in the Americas, suspicions...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dzieciolowska S, Larroque AL, Kranjec EA, Drapeau P, Samarut E. The larvicide pyriproxyfen blamed during the Zika virus outbreak does not cause microcephaly in zebrafish embryos. Sci Rep. 2017 Jan 4;7:40067. doi: 10.1038/srep40067.

Endoplasmic reticulum chaperone Gp96 controls actomyosin dynamics and protects against pore-forming toxins

Authors:
Mesquita FS, Brito C, Mazon Moya MJ, Pinheiro JC, Mostowy S, Cabanes D, Sousa S
Citation:
EMBO Rep. 2016 Dec 30. pii: e201642833. doi: 10.15252/embr.201642833. [Epub ahead of print]
Epub:
Yes
Abstract:
During infection, plasma membrane (PM) blebs protect host cells against bacterial pore-forming toxins (PFTs), but were also...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mesquita FS, Brito C, Mazon Moya MJ, Pinheiro JC, Mostowy S, Cabanes D, Sousa S. Endoplasmic reticulum chaperone Gp96 controls actomyosin dynamics and protects against pore-forming toxins. EMBO Rep. 2016 Dec 30. pii: e201642833. doi: 10.15252/embr.201642833. [Epub ahead of print].

Ndrg1b and fam49ab modulate the PTEN pathway to control T-cell lymphopoiesis in the zebrafish

Authors:
Li RA, Traver D, Matthes T, Bertrand JY
Citation:
Blood. 2016 Dec 29;128(26):3052-3060. doi: 10.1182/blood-2016-09-742502
Epub:
Not Epub
Abstract:
During hematopoiesis, the balance between proliferation, differentiation, and apoptosis is tightly regulated in order to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li RA, Traver D, Matthes T, Bertrand JY. Ndrg1b and fam49ab modulate the PTEN pathway to control T-cell lymphopoiesis in the zebrafish. Blood. 2016 Dec 29;128(26):3052-3060. doi: 10.1182/blood-2016-09-742502.

Purinergic P2Y Receptors Are Involved in Xenopus Head Formation

Authors:
Harata A, Nishida H, Nishihara A, Hashimoto C
Citation:
CellBio. 2016;5(4):49-65. doi:10.4236/cellbio.2016.54004
Epub:
Not Epub
Abstract:
P2Y receptors belong to the family of G protein-coupled receptors and are activated by nucleotides in the extracellular space....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Harata A, Nishida H, Nishihara A, Hashimoto C. Purinergic P2Y Receptors Are Involved in Xenopus Head Formation. CellBio. 2016;5(4):49-65. doi:10.4236/cellbio.2016.54004.

Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal

Authors:
Yang PH, Cheung WK, Peng Y, He ML, Wu GQ, Xie D, Jiang BH, Huang QH, Chen Z, Lin MC, Kung HF
Citation:
J Biol Chem. 2008 Mar 28;283(13):8486-95. doi: 10.1074/jbc.M704768200
Epub:
Not Epub
Abstract:
Makorin-2 belongs to the makorin RING zinc finger gene family, which encodes putative ribonucleoproteins. Here we cloned the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Yang PH, Cheung WK, Peng Y, He ML, Wu GQ, Xie D, Jiang BH, Huang QH, Chen Z, Lin MC, Kung HF. Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal. J Biol Chem. 2008 Mar 28;283(13):8486-95. doi: 10.1074/jbc.M704768200.

The presence of Anf/Hesx1 homeobox gene in lampreys suggests that it could play an important role in emergence of telencephalon

Authors:
Bayramov AV, Ermakova GV, Eroshkin FM, Kucheryavyy AV, Martynova NY, Zaraisky AG
Citation:
Sci Rep. 2016 Dec 23;6:39849. doi: 10.1038/srep39849
Epub:
Not Epub
Abstract:
Accumulated evidence indicates that the core genetic mechanisms regulating early patterning of the brain rudiment in...
Delivery Method:
microinjection
Organism or Cell Type:
Lampetra fluviatilis (lamprey), Xenopus laevis
Citation Extract:
Bayramov AV, Ermakova GV, Eroshkin FM, Kucheryavyy AV, Martynova NY, Zaraisky AG. The presence of Anf/Hesx1 homeobox gene in lampreys suggests that it could play an important role in emergence of telencephalon. Sci Rep. 2016 Dec 23;6:39849. doi: 10.1038/srep39849.

Lens defects in Astyanax mexicanus Cavefish: evolution of crystallins and a role for alphaA-crystallin

Authors:
Hinaux H, Blin M, Fumey J, Legendre L, Heuzé A, Casane D, Rétaux S
Citation:
Dev Neurobiol. 2015 May;75(5):505-21. doi: 10.1002/dneu.22239
Epub:
Not Epub
Abstract:
The fish Astyanax mexicanus presents, within the same species, populations of river-dwelling surface fish (SF) and blind cave-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hinaux H, Blin M, Fumey J, Legendre L, Heuzé A, Casane D, Rétaux S. Lens defects in Astyanax mexicanus Cavefish: evolution of crystallins and a role for alphaA-crystallin. Dev Neurobiol. 2015 May;75(5):505-21. doi: 10.1002/dneu.22239.

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