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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome

Authors:
Kim JH, Shinde DN, Reijnders MR, Hauser NS, Belmonte RL, Wilson GR, Bosch DG, Bubulya PA, Shashi V, Petrovski S, Stone JK, Park EY, Veltman JA, Sinnema M, Stumpel CT, Draaisma JM, Nicolai J; University of Washington Center for Mendelian Genomics, Yntema HG, Lindstrom K, de Vries BB, Jewett T, Santoro SL, Vogt J; Deciphering Developmental Disorders Study, Bachman KK, Seeley AH, Krokosky A, Turner C, Rohena L, Hempel M, Kortüm F, Lessel D, Neu A, Strom TM, <authors removed - database limit> Begtrup A, Funari T, Schoch K, Stegmann AP, Stevens SJ, Zhang DE, Traver D, Yao X, MacArthur DG, Brunner HG, Mancini GM, Myers RM, Owen LB, Lim ST, Stachura DL, Vissers LE, Ahn EE
Citation:
Am J Hum Genet. 2016 Aug 17. pii: S0002-9297(16)30267-1. doi: 10.1016/j.ajhg.2016.06.029. [Epub ahead of print]
Epub:
Yes
Abstract:
The overall understanding of the molecular etiologies of intellectual disability (ID) and developmental delay (DD) is...
Organism or Cell Type:
zebrafish
Citation Extract:
Kim JH, Shinde DN, Reijnders MR, Hauser NS, Belmonte RL, Wilson GR, Bosch DG, Bubulya PA, Shashi V, Petrovski S, Stone JK, Park EY, Veltman JA, Sinnema M, Stumpel CT, Draaisma JM, Nicolai J; University of Washington Center for Mendelian Genomics, Yntema HG, Lindstrom K, de Vries BB, Jewett T, Santoro SL, Vogt J; Deciphering Developmental Disorders Study, Bachman KK, Seeley AH, Krokosky A, Turner C, Rohena L, Hempel M, Kortüm F, Lessel D, Neu A, Strom TM, <authors removed - database limit> Begtrup A, Funari T, Schoch K, Stegmann AP, Stevens SJ, Zhang DE, Traver D, Yao X, MacArthur DG, Brunner HG, Mancini GM, Myers RM, Owen LB, Lim ST, Stachura DL, Vissers LE, Ahn EE. De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome. Am J Hum Genet. 2016 Aug 17. pii: S0002-9297(16)30267-1. doi: 10.1016/j.ajhg.2016.06.029. [Epub ahead of print].

Biallelic Variants in UBA5 Reveal that Disruption of the UFM1 Cascade Can Result in Early-Onset Encephalopathy

Authors:
Colin E, Daniel J, Ziegler A, Wakim J, Scrivo A, Haack TB, Khiati S, Denommé AS, Amati-Bonneau P, Charif M, Procaccio V, Reynier P, Aleck KA, Botto LD, Herper CL, Kaiser CS, Nabbout R, N'Guyen S, Mora-Lorca JA, Assmann B, Christ S, Meitinger T, Strom TM, Prokisch H; FREX Consortium, Miranda-Vizuete A, Hoffmann GF, Lenaers G, Bomont P, Liebau E, Bonneau D
Citation:
Am J Hum Genet. 2016 Aug 17. pii: S0002-9297(16)30268-3. doi: 10.1016/j.ajhg.2016.06.030. [Epub ahead of print]
Epub:
Yes
Abstract:
Via whole-exome sequencing, we identified rare autosomal-recessive variants in UBA5 in five children from four unrelated...
Organism or Cell Type:
zebrafish
Citation Extract:
Colin E, Daniel J, Ziegler A, Wakim J, Scrivo A, Haack TB, Khiati S, Denommé AS, Amati-Bonneau P, Charif M, Procaccio V, Reynier P, Aleck KA, Botto LD, Herper CL, Kaiser CS, Nabbout R, N'Guyen S, Mora-Lorca JA, Assmann B, Christ S, Meitinger T, Strom TM, Prokisch H; FREX Consortium, Miranda-Vizuete A, Hoffmann GF, Lenaers G, Bomont P, Liebau E, Bonneau D. Biallelic Variants in UBA5 Reveal that Disruption of the UFM1 Cascade Can Result in Early-Onset Encephalopathy. Am J Hum Genet. 2016 Aug 17. pii: S0002-9297(16)30268-3. doi: 10.1016/j.ajhg.2016.06.030. [Epub ahead of print].

G9a and ZNF644 Physically Associate to Suppress Progenitor Gene Expression during Neurogenesis

Authors:
Olsen JB, Wong L, Deimling S, Miles A, Guo H, Li Y, Zhang Z, Greenblatt JF, Emili A, Tropepe V
Citation:
Stem Cell Reports. 2016 Aug 17. pii: S2213-6711(16)30104-7. doi: 10.1016/j.stemcr.2016.06.012. [Epub ahead of print]
Epub:
Yes
Abstract:
Proliferating progenitor cells undergo changes in competence to give rise to post-mitotic progeny of specialized function....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Olsen JB, Wong L, Deimling S, Miles A, Guo H, Li Y, Zhang Z, Greenblatt JF, Emili A, Tropepe V. G9a and ZNF644 Physically Associate to Suppress Progenitor Gene Expression during Neurogenesis. Stem Cell Reports. 2016 Aug 17. pii: S2213-6711(16)30104-7. doi: 10.1016/j.stemcr.2016.06.012. [Epub ahead of print].

Studying cilia in zebrafish

Authors:
Drummond I
Citation:
Methods Cell Biol. 2009;93:197-217. doi: 10.1016/S0091-679X(08)93011-9. Epub 2009 Dec 4
Epub:
Not Epub
Abstract:
Zebrafish are ideally suited for analysis of genes required for ciliogenesis and cilia function. Combining genetic manipulation...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Drummond I. Studying cilia in zebrafish. Methods Cell Biol. 2009;93:197-217. doi: 10.1016/S0091-679X(08)93011-9. Epub 2009 Dec 4.

Analysis of IFT kinesins in developing zebrafish cone photoreceptor sensory cilia

Authors:
Insinna C, Luby-Phelps K, Link BA, Besharse JC
Citation:
Methods Cell Biol. 2009;93:219-34. doi: 10.1016/S0091-679X(08)93012-0. Epub 2009 Dec 4
Epub:
Not Epub
Abstract:
The photoreceptor outer segment (OS), a well-defined sensory cilium, provides an important context for the study of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Insinna C, Luby-Phelps K, Link BA, Besharse JC. Analysis of IFT kinesins in developing zebrafish cone photoreceptor sensory cilia. Methods Cell Biol. 2009;93:219-34. doi: 10.1016/S0091-679X(08)93012-0. Epub 2009 Dec 4.

Rapid microinjection of fertilized eggs

Authors:
Cheers MS, Ettensohn CA
Citation:
Methods Cell Biol. 2004;74:287-310
Epub:
Not Epub
Abstract:
The chapter focuses on methods for using a picospritzer to inject large numbers of eggs that have been immobilized in open...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus and Lytechinus variegatus (sea urchin)
Citation Extract:
Cheers MS, Ettensohn CA. Rapid microinjection of fertilized eggs. Methods Cell Biol. 2004;74:287-310.

Performing functional studies of Xenopus laevis intermediate filament proteins through injection of macromolecules into early embryos

Authors:
Gervasi C, Szaro BG
Citation:
Methods Cell Biol. 2004;78:673-701
Epub:
Not Epub
Abstract:
The small size of Xenopus laevis embryos and their external development make it easy to study early developmental stages in...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gervasi C, Szaro BG. Performing functional studies of Xenopus laevis intermediate filament proteins through injection of macromolecules into early embryos. Methods Cell Biol. 2004;78:673-701.

IGFBP1 increases β-cell regeneration by promoting α- to β-cell transdifferentiation

Authors:
Lu J, Liu KC, Schulz N, Karampelias C, Charbord J, Hilding A, Rautio L, Bertolino P, Östenson CG, Brismar K, Andersson O
Citation:
EMBO J. 2016 Aug 11. pii: e201592903. [Epub ahead of print]
Epub:
Yes
Abstract:
There is great interest in therapeutically harnessing endogenous regenerative mechanisms to increase the number of β cells in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu J, Liu KC, Schulz N, Karampelias C, Charbord J, Hilding A, Rautio L, Bertolino P, Östenson CG, Brismar K, Andersson O. IGFBP1 increases β-cell regeneration by promoting α- to β-cell transdifferentiation. EMBO J. 2016 Aug 11. pii: e201592903. [Epub ahead of print].

ARGLU1 is a Glucocorticoid Receptor Coactivator and Splicing Modulator Important in Stress Hormone Signaling and Brain Development

Authors:
Magomedova L, Tiefenbach J, Zilberman E, Voisin V, Robitaille M, Gueroussov S, Irimia M, Ray D, Patel R, Xu CJ, Jeyasuria P, Bader GD, Hughes TR, Krause H, Blencowe BJ, Angers S, Cummins CL
Citation:
bioRxiv 2016. doi:10.1101/069161
Epub:
Not Epub
Abstract:
Prolonged exposure to glucocorticoid stress hormones precipitates mood and cognitive disorders. We identified arginine and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Magomedova L, Tiefenbach J, Zilberman E, Voisin V, Robitaille M, Gueroussov S, Irimia M, Ray D, Patel R, Xu CJ, Jeyasuria P, Bader GD, Hughes TR, Krause H, Blencowe BJ, Angers S, Cummins CL. ARGLU1 is a Glucocorticoid Receptor Coactivator and Splicing Modulator Important in Stress Hormone Signaling and Brain Development. bioRxiv 2016. doi:10.1101/069161.

Synthesis of 5-alkynylated uracil–morpholino monomers using Sonogashira coupling

Authors:
Paul S, Nandi B, Pattanayak S, Sinha S
Citation:
Tetrahedron Lett. 2012;53:4179-83. doi:10.1016/j.tetlet.2012.05.141
Epub:
Not Epub
Abstract:
Sonogashira coupling of 5-iodo uracil–morpholino monomer with different terminal alkynes has been achieved for first time in...
Citation Extract:
Paul S, Nandi B, Pattanayak S, Sinha S. Synthesis of 5-alkynylated uracil–morpholino monomers using Sonogashira coupling. Tetrahedron Lett. 2012;53:4179-83. doi:10.1016/j.tetlet.2012.05.141.

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