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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Mutations in INPP5K, Encoding a Phosphoinositide 5-Phosphatase, Cause Congenital Muscular Dystrophy with Cataracts and Mild Cognitive Impairment

Authors:
Wiessner M, Roos A, Munn CJ, Viswanathan R, Whyte T, Cox D, Schoser B, Sewry C, Roper H, Phadke R, Marini Bettolo CM, Barresi R, Charlton R, Bönnemann CG, Neto OA, Reed UC, Zanoteli E, Moreno CAM, Ertl-Wagner B, Stucka R, De Goede C, da Silva TB, Hathazi D, Dell’Aica M, Zahedi RP, Thiele S, Müller J, Kingston H, Müller S, Curtis E, Walter MC, Strom TM, Straub V, Bushby K, Muntoni F, Swan LE, Lochmüller H, Senderek J
Citation:
Am J Hum Genet. 2017;[Epub ahead of print] doi:10.1016/j.ajhg.2017.01.024
Epub:
Yes
Abstract:
Phosphoinositides are small phospholipids that control diverse cellular downstream signaling events. Their spatial and temporal...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297(17)30024-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wiessner M, Roos A, Munn CJ, Viswanathan R, Whyte T, Cox D, Schoser B, Sewry C, Roper H, Phadke R, Marini Bettolo CM, Barresi R, Charlton R, Bönnemann CG, Neto OA, Reed UC, Zanoteli E, Moreno CAM, Ertl-Wagner B, Stucka R, De Goede C, da Silva TB, Hathazi D, Dell’Aica M, Zahedi RP, Thiele S, Müller J, Kingston H, Müller S, Curtis E, Walter MC, Strom TM, Straub V, Bushby K, Muntoni F, Swan LE, Lochmüller H, Senderek J. Mutations in INPP5K, Encoding a Phosphoinositide 5-Phosphatase, Cause Congenital Muscular Dystrophy with Cataracts and Mild Cognitive Impairment. Am J Hum Genet. 2017;[Epub ahead of print] doi:10.1016/j.ajhg.2017.01.024.

Impairment of cargo transportation due to gbf1 mutation disrupts vascular integrity and causes hemorrhage in zebrafish embryos

Authors:
Chen J, Wu X, Yao L, Yan L, Zhang L, Qiu J, Liu X, Jia S, Meng A
Citation:
J Biol Chem. 2016 Dec 21. pii: jbc.M116.767608. doi: 10.1074/jbc.M116.767608. [Epub ahead of print]
Epub:
Yes
Abstract:
ADP-ribosylation factor (ARF) GTPases are activated by guanine nucleotide exchange factors including Golgi Brefeldin A-...
Link:
http://www.jbc.org/content/292/6/2315.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Chen J, Wu X, Yao L, Yan L, Zhang L, Qiu J, Liu X, Jia S, Meng A. Impairment of cargo transportation due to gbf1 mutation disrupts vascular integrity and causes hemorrhage in zebrafish embryos. J Biol Chem. 2016 Dec 21. pii: jbc.M116.767608. doi: 10.1074/jbc.M116.767608. [Epub ahead of print].

Mutations in INPP5K Cause a Form of Congenital Muscular Dystrophy Overlapping Marinesco-Sjögren Syndrome and Dystroglycanopathy

Authors:
Osborn DPS, Pond HL, Mazaheri N, Dejardin J, Munn CJ, Mushref K, Cauley ES, Moroni I, Pasanisi MB, Sellars EA, Hill RS, Partlow JN, Willaert RK, Bharj J, Malamiri RA, Galehdari H, Shariati G, Maroofian R, Mora M, Swan LE, Voit T, Conti FJ, Jamshidi Y, Manzini MC
Citation:
Am J Hum Genet. 2017;[Epub ahead of print] doi:10.1016/j.ajhg.2017.01.019
Epub:
Not Epub
Abstract:
Congenital muscular dystrophies display a wide phenotypic and genetic heterogeneity. The combination of clinical, biochemical,...
Link:
http://www.cell.com/ajhg/fulltext/S0002-9297(17)30019-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Osborn DPS, Pond HL, Mazaheri N, Dejardin J, Munn CJ, Mushref K, Cauley ES, Moroni I, Pasanisi MB, Sellars EA, Hill RS, Partlow JN, Willaert RK, Bharj J, Malamiri RA, Galehdari H, Shariati G, Maroofian R, Mora M, Swan LE, Voit T, Conti FJ, Jamshidi Y, Manzini MC. Mutations in INPP5K Cause a Form of Congenital Muscular Dystrophy Overlapping Marinesco-Sjögren Syndrome and Dystroglycanopathy. Am J Hum Genet. 2017;[Epub ahead of print] doi:10.1016/j.ajhg.2017.01.019.

Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes

Authors:
Place ES, Smith JC
Citation:
PLoS One. 2017 Feb 9;12(2):e0171143. doi: 10.1371/journal.pone.0171143
Epub:
Not Epub
Abstract:
Atoh8 is a bHLH transcription factor expressed in pancreas, skeletal muscle, the nervous system, and cardiovascular tissues...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0171143
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Place ES, Smith JC. Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes. PLoS One. 2017 Feb 9;12(2):e0171143. doi: 10.1371/journal.pone.0171143.

Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling

Authors:
Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K
Citation:
Circul Res. 2017;[Epub ahead of print] doi:10.1161/CIRCRESAHA.116.308825
Epub:
Not Epub
Abstract:
Rationale: Lymphatic vasculature constitutes a second vascular system, essential for immune surveillance and tissue fluid...
Link:
http://circres.ahajournals.org/content/early/2017/02/08/CIRCRESAHA.116.308825
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K. Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circul Res. 2017;[Epub ahead of print] doi:10.1161/CIRCRESAHA.116.308825.

Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors

Authors:
Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee H-Y, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, Agarwal S, Ebert BL, Gazda HT, Lodish HF, Sieff CA, Schlaeger TM, Zon LI, Daley GQ
Citation:
Science Transl Med. 2017;9(376). doi:10.1126/scitranslmed.aah5645
Epub:
Not Epub
Abstract:
Diamond-Blackfan anemia (DBA) is a congenital disorder characterized by the failure of erythroid progenitor differentiation,...
Link:
http://stm.sciencemag.org/content/9/376/eaah5645.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee H-Y, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, Agarwal S, Ebert BL, Gazda HT, Lodish HF, Sieff CA, Schlaeger TM, Zon LI, Daley GQ. Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors. Science Transl Med. 2017;9(376). doi:10.1126/scitranslmed.aah5645.

DM-GRASP/ALCAM/CD166 is required for cardiac morphogenesis and maintenance of cardiac identity in first heart field derived cells

Authors:
Gessert S, Maurus D, Brade T, Walther P, Pandur P, Kühl M
Citation:
Dev Biol. 2008 Sep 1;321(1):150-61. doi: 10.1016/j.ydbio.2008.06.013
Epub:
Not Epub
Abstract:
Vertebrate heart development requires specification of cardiac precursor cells, migration of cardiac progenitors as well as...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160608010038
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gessert S, Maurus D, Brade T, Walther P, Pandur P, Kühl M. DM-GRASP/ALCAM/CD166 is required for cardiac morphogenesis and maintenance of cardiac identity in first heart field derived cells. Dev Biol. 2008 Sep 1;321(1):150-61. doi: 10.1016/j.ydbio.2008.06.013.

Tbx2 regulates anterior neural specification by repressing FGF signaling pathway

Authors:
Cho GS, Park DS, Choi SC, Han JK
Citation:
Dev Biol. 2017 Jan 15;421(2):183-193. doi: 10.1016/j.ydbio.2016.11.020
Epub:
Not Epub
Abstract:
During early embryogenesis, FGF signals regulate the antero-posterior (AP) patterning of the neural plate by promoting...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616303402
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Cho GS, Park DS, Choi SC, Han JK. Tbx2 regulates anterior neural specification by repressing FGF signaling pathway. Dev Biol. 2017 Jan 15;421(2):183-193. doi: 10.1016/j.ydbio.2016.11.020.

RhoA regulates actin network dynamics during apical surface emergence in multiciliated epithelial cells

Authors:
Sedzinski J, Hannezo E, Tu F, Biro M, Wallingford JB
Citation:
J Cell Sci. 2017 Jan 15;130(2):420-428. doi: 10.1242/jcs.194704
Epub:
Not Epub
Abstract:
Homeostatic replacement of epithelial cells from basal precursors is a multistep process involving progenitor cell...
Link:
http://jcs.biologists.org/content/130/2/420
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Sedzinski J, Hannezo E, Tu F, Biro M, Wallingford JB. RhoA regulates actin network dynamics during apical surface emergence in multiciliated epithelial cells. J Cell Sci. 2017 Jan 15;130(2):420-428. doi: 10.1242/jcs.194704.

An exclusive cellular and molecular network governs intestinal smooth muscle cell differentiation in vertebrates

Authors:
Gays D, Hess C, Camporeale A, Ala U, Provero P, Mosimann C, Santoro MM
Citation:
Development. 2017 Feb 1;144(3):464-478. doi: 10.1242/dev.133926
Epub:
Not Epub
Abstract:
Intestinal smooth muscle cells (iSMCs) are a crucial component of the adult gastrointestinal tract and support intestinal...
Link:
http://dev.biologists.org/content/144/3/464
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gays D, Hess C, Camporeale A, Ala U, Provero P, Mosimann C, Santoro MM. An exclusive cellular and molecular network governs intestinal smooth muscle cell differentiation in vertebrates. Development. 2017 Feb 1;144(3):464-478. doi: 10.1242/dev.133926.

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