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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

LIM Domain Only 2 Regulates Endothelial Proliferation, Angiogenesis, and Tissue Regeneration

Authors:
Meng S, Matrone G, Lv J, Chen K, Wong WT, Cooke JP
Citation:
J Am Heart Assoc. 2016 Oct 6;5(10). pii: e004117
Epub:
Not Epub
Abstract:
BACKGROUND: LIM domain only 2 (LMO2, human gene) is a key transcription factor that regulates hematopoiesis and vascular...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Meng S, Matrone G, Lv J, Chen K, Wong WT, Cooke JP. LIM Domain Only 2 Regulates Endothelial Proliferation, Angiogenesis, and Tissue Regeneration. J Am Heart Assoc. 2016 Oct 6;5(10). pii: e004117.

MicroRNA-126a Directs Lymphangiogenesis Through Interacting With Chemokine and Flt4 Signaling in Zebrafish

Authors:
Chen J, Zhu RF, Li FF, Liang YL, Wang C, Qin YW, Huang S, Zhao XX, Jing Q
Citation:
Arterioscler Thromb Vasc Biol. 2016 Oct 27. pii: ATVBAHA.116.308120. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVE: MicroRNA-126 (miR-126) is an endothelium-enriched miRNA and functions in vascular integrity and angiogenesis. The...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen J, Zhu RF, Li FF, Liang YL, Wang C, Qin YW, Huang S, Zhao XX, Jing Q. MicroRNA-126a Directs Lymphangiogenesis Through Interacting With Chemokine and Flt4 Signaling in Zebrafish. Arterioscler Thromb Vasc Biol. 2016 Oct 27. pii: ATVBAHA.116.308120. [Epub ahead of print].

Zebrafish embryos as in vivo test tubes to unravel cell-specific mechanisms of neurogenesis during neurodevelopment and in diseases

Authors:
Samarut É
Citation:
Neurogenesis (Austin). 2016 Oct 7;3(1):e1232678
Epub:
Not Epub
Abstract:
Zebrafish has become a model of choice for developmental studies in particular for studying neural development and related...
Organism or Cell Type:
zebrafish
Citation Extract:
Samarut É. Zebrafish embryos as in vivo test tubes to unravel cell-specific mechanisms of neurogenesis during neurodevelopment and in diseases. Neurogenesis (Austin). 2016 Oct 7;3(1):e1232678.

Caspase-2 cleavage of tau reversibly impairs memory

Authors:
Zhao X, Kotilinek LA, Smith B, Hlynialuk C, Zahs K, Ramsden M, Cleary J, Ashe KH
Citation:
Nat Med. 2016 Oct 10. doi: 10.1038/nm.4199
Epub:
Not Epub
Abstract:
In Alzheimer's disease (AD) and other tauopathies, the tau protein forms fibrils, which are believed to be neurotoxic....
Delivery Method:
icv infusion
Organism or Cell Type:
mice
Citation Extract:
Zhao X, Kotilinek LA, Smith B, Hlynialuk C, Zahs K, Ramsden M, Cleary J, Ashe KH. Caspase-2 cleavage of tau reversibly impairs memory. Nat Med. 2016 Oct 10. doi: 10.1038/nm.4199.

Cnbp ameliorates Treacher Collins Syndrome craniofacial anomalies through a pathway that involves redox-responsive genes

Authors:
de Peralta MS, Mouguelar VS, Sdrigotti MA, Ishiy FA, Fanganiello RD, Passos-Bueno MR, Coux G, Calcaterra NB
Citation:
Cell Death Dis. 2016 Oct 6;7(10):e2397. doi: 10.1038/cddis.2016.299
Epub:
Not Epub
Abstract:
Treacher Collins Syndrome (TCS) is a rare congenital disease (1:50 000 live births) characterized by craniofacial defects,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
de Peralta MS, Mouguelar VS, Sdrigotti MA, Ishiy FA, Fanganiello RD, Passos-Bueno MR, Coux G, Calcaterra NB. Cnbp ameliorates Treacher Collins Syndrome craniofacial anomalies through a pathway that involves redox-responsive genes. Cell Death Dis. 2016 Oct 6;7(10):e2397. doi: 10.1038/cddis.2016.299.

Spatiotemporal expression and transcriptional regulation of heme oxygenase and biliverdin reductase genes in zebrafish (Danio rerio) suggest novel roles during early developmental periods of heightened oxidative stress

Authors:
Holowiecki A, O'Shields B, Jenny MJ
Citation:
Comp Biochem Physiol C Toxicol Pharmacol. 2016 Oct 17. pii: S1532-0456(16)30132-6. doi: 10.1016/j.cbpc.2016.10.006
Epub:
Yes
Abstract:
Heme oxygenase 1 (HMOX1) degrades heme into biliverdin, which is subsequently converted to bilirubin by biliverdin reductase (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Holowiecki A, O'Shields B, Jenny MJ. Spatiotemporal expression and transcriptional regulation of heme oxygenase and biliverdin reductase genes in zebrafish (Danio rerio) suggest novel roles during early developmental periods of heightened oxidative stress. Comp Biochem Physiol C Toxicol Pharmacol. 2016 Oct 17. pii: S1532-0456(16)30132-6. doi: 10.1016/j.cbpc.2016.10.006.

The zebrafish homologs of SET/I2PP2A oncoprotein: expression patterns and insights into their physiological roles during development

Authors:
Serifi I, Tzima E, Soupsana K, Karetsou Z, Beis D, Papamarcaki T
Citation:
Biochem J. 2016 Oct 17. pii: BCJ20160523 [epub ahead of print]. doi:10.1042/BCJ20160523
Epub:
Yes
Abstract:
The oncoprotein SET/I2PP2A participates in various cellular mechanisms such as transcription, cell cycle regulation and cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Serifi I, Tzima E, Soupsana K, Karetsou Z, Beis D, Papamarcaki T. The zebrafish homologs of SET/I2PP2A oncoprotein: expression patterns and insights into their physiological roles during development. Biochem J. 2016 Oct 17. pii: BCJ20160523 [epub ahead of print]. doi:10.1042/BCJ20160523.

Loss of a Candidate Biliary Atresia Susceptibility Gene, add3a, Causes Biliary Developmental Defects in Zebrafish

Authors:
Tang V, Cofer ZC, Cui S, Sapp V, Loomes KM, Matthews RP
Citation:
J Pediatr Gastroenterol Nutr. 2016 Nov;63(5):524-530. doi:10.1097/MPG.0000000000001375
Epub:
Not Epub
Abstract:
OBJECTIVES: Biliary atresia (BA) is a progressive fibroinflammatory cholangiopathy affecting the bile ducts of neonates....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tang V, Cofer ZC, Cui S, Sapp V, Loomes KM, Matthews RP. Loss of a Candidate Biliary Atresia Susceptibility Gene, add3a, Causes Biliary Developmental Defects in Zebrafish. J Pediatr Gastroenterol Nutr. 2016 Nov;63(5):524-530. doi:10.1097/MPG.0000000000001375.

Mutation in SSUH2 Causes Autosomal-Dominant Dentin Dysplasia Type I

Authors:
Xiong F, Ji Z, Liu Y, Zhang Y, Hu L, Yang Q, Qiu Q, Zhao L, Chen D, Tian Z, Shang X, Zhang L, Wei X, Liu C, Yu Q, Zhang M, Cheng J, Xiong J, Li D, Wu X, Yuan H, Zhang W, Xu X
Citation:
Hum Mutat. 2016 Sep 29. doi: 10.1002/humu.23130
Epub:
Yes
Abstract:
Dentin dysplasia type I (DDI) is an autosomal-dominant genetic disorder resulting from dentin defects. The molecular basis of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xiong F, Ji Z, Liu Y, Zhang Y, Hu L, Yang Q, Qiu Q, Zhao L, Chen D, Tian Z, Shang X, Zhang L, Wei X, Liu C, Yu Q, Zhang M, Cheng J, Xiong J, Li D, Wu X, Yuan H, Zhang W, Xu X. Mutation in SSUH2 Causes Autosomal-Dominant Dentin Dysplasia Type I. Hum Mutat. 2016 Sep 29. doi: 10.1002/humu.23130.

HIF1α-induced PDGFRβ signaling promotes developmental HSC production via IL-6 activation

Authors:
Lim SE, Esain V, Kwan W, Theodore LN, Cortes M, Frost IM, Liu SY, North TE
Citation:
Exp Hematol. 2016 Oct 14. pii: S0301-472X(16)30657-9. [Epub ahead of print] doi: 10.1016/j.exphem.2016.10.002
Epub:
Yes
Abstract:
Hematopoietic stem cells (HSCs) have the ability to both self-renew and differentiate into all the mature blood cell lineages...
Citation Extract:
Lim SE, Esain V, Kwan W, Theodore LN, Cortes M, Frost IM, Liu SY, North TE. HIF1α-induced PDGFRβ signaling promotes developmental HSC production via IL-6 activation. Exp Hematol. 2016 Oct 14. pii: S0301-472X(16)30657-9. [Epub ahead of print] doi: 10.1016/j.exphem.2016.10.002.

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