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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

EphA7 modulates apical constriction of hindbrain neuroepithelium during neurulation in Xenopus

Authors:
Wang X, Sun J, Li C, Mao B
Citation:
Biochem Biophys Res Commun. 2016 Sep 27. pii: S0006-291X(16)31612-6. doi: 10.1016/j.bbrc.2016.09.138
Epub:
Yes
Abstract:
Eph receptor tyrosine kinases (RTKs) and their ephrin ligands play multiple roles in the developing nervous system, including...
Organism or Cell Type:
Xenopus
Citation Extract:
Wang X, Sun J, Li C, Mao B. EphA7 modulates apical constriction of hindbrain neuroepithelium during neurulation in Xenopus. Biochem Biophys Res Commun. 2016 Sep 27. pii: S0006-291X(16)31612-6. doi: 10.1016/j.bbrc.2016.09.138.

Phosphorylation of Kif26b Promotes Its Polyubiquitination and Subsequent Proteasomal Degradation during Kidney Development

Authors:
Terabayashi T, Sakaguchi M, Shinmyozu K, Ohshima T, Johjima A, Ogura T, Miki H, Nishinakamura R
Citation:
PLoS ONE. 2012;7(6): e39714. doi:10.1371/journal.pone.0039714
Epub:
Not Epub
Abstract:
Kif26b, a member of the kinesin superfamily proteins (KIFs), is essential for kidney development. Kif26b expression is...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse kidney explant
Citation Extract:
Terabayashi T, Sakaguchi M, Shinmyozu K, Ohshima T, Johjima A, Ogura T, Miki H, Nishinakamura R. Phosphorylation of Kif26b Promotes Its Polyubiquitination and Subsequent Proteasomal Degradation during Kidney Development. PLoS ONE. 2012;7(6): e39714. doi:10.1371/journal.pone.0039714.

Quantitative imaging reveals real-time Pou5f3-Nanog complexes driving dorsoventral mesendoderm patterning in zebrafish

Authors:
Perez-Camps M, Tian J, Chng SC, Sem KP, Sudhaharan T, Teh C, Wachsmuth M, Korzh V, Ahmed S, Reversade B
Citation:
Elife. 2016 Sep 29;5. pii: e11475. doi: 10.7554/eLife.11475
Epub:
Not Epub
Abstract:
Formation of the three embryonic germ layers is a fundamental developmental process that initiates differentiation. How the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Perez-Camps M, Tian J, Chng SC, Sem KP, Sudhaharan T, Teh C, Wachsmuth M, Korzh V, Ahmed S, Reversade B. Quantitative imaging reveals real-time Pou5f3-Nanog complexes driving dorsoventral mesendoderm patterning in zebrafish. Elife. 2016 Sep 29;5. pii: e11475. doi: 10.7554/eLife.11475.

Leucine-rich repeat containing protein LRRC8A is essential for swelling-activated Cl- currents and embryonic development in zebrafish

Authors:
Yamada T, Wondergem R, Morrison R, Yin VP, Strange K
Citation:
Physiol Rep. 2016 Oct;4(19). pii: e12940. doi: 10.14814/phy2.12940
Epub:
Not Epub
Abstract:
A volume-regulated anion channel (VRAC) has been electrophysiologically characterized in innumerable mammalian cell types. VRAC...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yamada T, Wondergem R, Morrison R, Yin VP, Strange K. Leucine-rich repeat containing protein LRRC8A is essential for swelling-activated Cl- currents and embryonic development in zebrafish. Physiol Rep. 2016 Oct;4(19). pii: e12940. doi: 10.14814/phy2.12940.

Novel roles for the radial spoke head protein 9 in neural and neurosensory cilia

Authors:
Sedykh I, TeSlaa JJ, Tatarsky RL, Keller AN, Toops KA, Lakkaraju A, Nyholm MK, Wolman MA, Grinblat Y
Citation:
Sci Rep. 2016;6:34437. doi:10.1038/srep34437
Epub:
Not Epub
Abstract:
Cilia are cell surface organelles with key roles in a range of cellular processes, including generation of fluid flow by motile...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sedykh I, TeSlaa JJ, Tatarsky RL, Keller AN, Toops KA, Lakkaraju A, Nyholm MK, Wolman MA, Grinblat Y. Novel roles for the radial spoke head protein 9 in neural and neurosensory cilia. Sci Rep. 2016;6:34437. doi:10.1038/srep34437.

Affinity Labeling Detection of Endogenous Receptors from Zebrafish Embryos

Authors:
Molina-Villa T, Mendoza V, López-Casillas F
Citation:
J Vis Exp. 2016 Aug 31;(114). doi: 10.3791/54405
Epub:
Not Epub
Abstract:
By combining the powers of Affinity Labeling and Immunoprecipitation (AFLIP), a technique for the detection of low abundance...
Organism or Cell Type:
zebrafish
Citation Extract:
Molina-Villa T, Mendoza V, López-Casillas F. Affinity Labeling Detection of Endogenous Receptors from Zebrafish Embryos. J Vis Exp. 2016 Aug 31;(114). doi: 10.3791/54405.

Mutation in SSUH2 Causes Autosomal Dominant Dentin Dysplasia Type I

Authors:
Xiong F, Ji Z, Liu Y, Zhang Y, Hu L, Yang Q, Qiu Q, Zhao L, Chen D, Tian Z, Shang X, Zhang L, Wei X, Liu C, Yu Q, Zhang M, Cheng J, Xiong J, Li D, Wu X, Yuan H, Zhang W, Xu X
Citation:
Hum Mutat. 2016 Sep 29. doi: 10.1002/humu.23130. [Epub ahead of print]
Epub:
Yes
Abstract:
Dentin dysplasia type I (DDI) is an autosomal-dominant genetic disorder resulting from dentin defects. The molecular basis of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xiong F, Ji Z, Liu Y, Zhang Y, Hu L, Yang Q, Qiu Q, Zhao L, Chen D, Tian Z, Shang X, Zhang L, Wei X, Liu C, Yu Q, Zhang M, Cheng J, Xiong J, Li D, Wu X, Yuan H, Zhang W, Xu X. Mutation in SSUH2 Causes Autosomal Dominant Dentin Dysplasia Type I. Hum Mutat. 2016 Sep 29. doi: 10.1002/humu.23130. [Epub ahead of print].

Cullin9 protects mouse eggs from aneuploidy by controlling microtubule dynamics via Survivin

Authors:
Dai X, Zhang M, Lu Y, Miao Y, Zhou C, Xiong B
Citation:
Biochim Biophys Acta. 2016 Sep 24. pii: S0167-4889(16)30246-4. doi: 10.1016/j.bbamcr.2016.09.017. [Epub ahead of print]
Epub:
Yes
Abstract:
The Cullin9 gene encodes a putative E3 ligase that serves a wide variety of biological functions in mitosis, whereas its roles...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Dai X, Zhang M, Lu Y, Miao Y, Zhou C, Xiong B. Cullin9 protects mouse eggs from aneuploidy by controlling microtubule dynamics via Survivin. Biochim Biophys Acta. 2016 Sep 24. pii: S0167-4889(16)30246-4. doi: 10.1016/j.bbamcr.2016.09.017. [Epub ahead of print].

Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy

Authors:
Sicca F, Ambrosini E, Marchese M, Sforna L, Servettini I, Valvo G, Brignone MS, Lanciotti A, Moro F, Grottesi A, Catacuzzeno L, Baldini S, Hasan S, D’Adamo MC, Franciolini F, Molinari P, Santorelli FM, Pessia M
Citation:
Sci Rep. 2016;6:34325. doi:10.1038/srep34325
Epub:
Not Epub
Abstract:
Dysfunction of the inwardly-rectifying potassium channels Kir4.1 (KCNJ10) represents a pathogenic mechanism contributing to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sicca F, Ambrosini E, Marchese M, Sforna L, Servettini I, Valvo G, Brignone MS, Lanciotti A, Moro F, Grottesi A, Catacuzzeno L, Baldini S, Hasan S, D’Adamo MC, Franciolini F, Molinari P, Santorelli FM, Pessia M. Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy. Sci Rep. 2016;6:34325. doi:10.1038/srep34325.

HB-GAM (pleiotrophin) reverses inhibition of neural regeneration by the CNS extracellular matrix

Authors:
Paveliev M, Fenrich KK, Kislin M, Kuja-Panula J, Kulesskiy E, Varjosalo M, Kajander T, Mugantseva E, Ahonen-Bishopp A, Khiroug L, Kulesskaya N, Rougon G, Rauvala H
Citation:
Sci Rep. 2016;6:33916. doi:10.1038/srep33916
Epub:
Not Epub
Abstract:
Chondroitin sulfate (CS) glycosaminoglycans inhibit regeneration in the adult central nervous system (CNS). We report here that...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cultured cells: mouse E17 cortical neurons
Citation Extract:
Paveliev M, Fenrich KK, Kislin M, Kuja-Panula J, Kulesskiy E, Varjosalo M, Kajander T, Mugantseva E, Ahonen-Bishopp A, Khiroug L, Kulesskaya N, Rougon G, Rauvala H. HB-GAM (pleiotrophin) reverses inhibition of neural regeneration by the CNS extracellular matrix. Sci Rep. 2016;6:33916. doi:10.1038/srep33916.

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