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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12165 scientific papers returned from the database with the search filters currently being used below.

Leucine-rich repeat containing protein LRRC8A is essential for swelling-activated Cl- currents and embryonic development in zebrafish

Authors:
Yamada T, Wondergem R, Morrison R, Yin VP, Strange K
Citation:
Physiol Rep. 2016 Oct;4(19). pii: e12940. doi: 10.14814/phy2.12940
Epub:
Not Epub
Abstract:
A volume-regulated anion channel (VRAC) has been electrophysiologically characterized in innumerable mammalian cell types. VRAC...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yamada T, Wondergem R, Morrison R, Yin VP, Strange K. Leucine-rich repeat containing protein LRRC8A is essential for swelling-activated Cl- currents and embryonic development in zebrafish. Physiol Rep. 2016 Oct;4(19). pii: e12940. doi: 10.14814/phy2.12940.

Novel roles for the radial spoke head protein 9 in neural and neurosensory cilia

Authors:
Sedykh I, TeSlaa JJ, Tatarsky RL, Keller AN, Toops KA, Lakkaraju A, Nyholm MK, Wolman MA, Grinblat Y
Citation:
Sci Rep. 2016;6:34437. doi:10.1038/srep34437
Epub:
Not Epub
Abstract:
Cilia are cell surface organelles with key roles in a range of cellular processes, including generation of fluid flow by motile...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sedykh I, TeSlaa JJ, Tatarsky RL, Keller AN, Toops KA, Lakkaraju A, Nyholm MK, Wolman MA, Grinblat Y. Novel roles for the radial spoke head protein 9 in neural and neurosensory cilia. Sci Rep. 2016;6:34437. doi:10.1038/srep34437.

Affinity Labeling Detection of Endogenous Receptors from Zebrafish Embryos

Authors:
Molina-Villa T, Mendoza V, López-Casillas F
Citation:
J Vis Exp. 2016 Aug 31;(114). doi: 10.3791/54405
Epub:
Not Epub
Abstract:
By combining the powers of Affinity Labeling and Immunoprecipitation (AFLIP), a technique for the detection of low abundance...
Organism or Cell Type:
zebrafish
Citation Extract:
Molina-Villa T, Mendoza V, López-Casillas F. Affinity Labeling Detection of Endogenous Receptors from Zebrafish Embryos. J Vis Exp. 2016 Aug 31;(114). doi: 10.3791/54405.

Mutation in SSUH2 Causes Autosomal Dominant Dentin Dysplasia Type I

Authors:
Xiong F, Ji Z, Liu Y, Zhang Y, Hu L, Yang Q, Qiu Q, Zhao L, Chen D, Tian Z, Shang X, Zhang L, Wei X, Liu C, Yu Q, Zhang M, Cheng J, Xiong J, Li D, Wu X, Yuan H, Zhang W, Xu X
Citation:
Hum Mutat. 2016 Sep 29. doi: 10.1002/humu.23130. [Epub ahead of print]
Epub:
Yes
Abstract:
Dentin dysplasia type I (DDI) is an autosomal-dominant genetic disorder resulting from dentin defects. The molecular basis of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xiong F, Ji Z, Liu Y, Zhang Y, Hu L, Yang Q, Qiu Q, Zhao L, Chen D, Tian Z, Shang X, Zhang L, Wei X, Liu C, Yu Q, Zhang M, Cheng J, Xiong J, Li D, Wu X, Yuan H, Zhang W, Xu X. Mutation in SSUH2 Causes Autosomal Dominant Dentin Dysplasia Type I. Hum Mutat. 2016 Sep 29. doi: 10.1002/humu.23130. [Epub ahead of print].

Cullin9 protects mouse eggs from aneuploidy by controlling microtubule dynamics via Survivin

Authors:
Dai X, Zhang M, Lu Y, Miao Y, Zhou C, Xiong B
Citation:
Biochim Biophys Acta. 2016 Sep 24. pii: S0167-4889(16)30246-4. doi: 10.1016/j.bbamcr.2016.09.017. [Epub ahead of print]
Epub:
Yes
Abstract:
The Cullin9 gene encodes a putative E3 ligase that serves a wide variety of biological functions in mitosis, whereas its roles...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Dai X, Zhang M, Lu Y, Miao Y, Zhou C, Xiong B. Cullin9 protects mouse eggs from aneuploidy by controlling microtubule dynamics via Survivin. Biochim Biophys Acta. 2016 Sep 24. pii: S0167-4889(16)30246-4. doi: 10.1016/j.bbamcr.2016.09.017. [Epub ahead of print].

Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy

Authors:
Sicca F, Ambrosini E, Marchese M, Sforna L, Servettini I, Valvo G, Brignone MS, Lanciotti A, Moro F, Grottesi A, Catacuzzeno L, Baldini S, Hasan S, D’Adamo MC, Franciolini F, Molinari P, Santorelli FM, Pessia M
Citation:
Sci Rep. 2016;6:34325. doi:10.1038/srep34325
Epub:
Not Epub
Abstract:
Dysfunction of the inwardly-rectifying potassium channels Kir4.1 (KCNJ10) represents a pathogenic mechanism contributing to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sicca F, Ambrosini E, Marchese M, Sforna L, Servettini I, Valvo G, Brignone MS, Lanciotti A, Moro F, Grottesi A, Catacuzzeno L, Baldini S, Hasan S, D’Adamo MC, Franciolini F, Molinari P, Santorelli FM, Pessia M. Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy. Sci Rep. 2016;6:34325. doi:10.1038/srep34325.

HB-GAM (pleiotrophin) reverses inhibition of neural regeneration by the CNS extracellular matrix

Authors:
Paveliev M, Fenrich KK, Kislin M, Kuja-Panula J, Kulesskiy E, Varjosalo M, Kajander T, Mugantseva E, Ahonen-Bishopp A, Khiroug L, Kulesskaya N, Rougon G, Rauvala H
Citation:
Sci Rep. 2016;6:33916. doi:10.1038/srep33916
Epub:
Not Epub
Abstract:
Chondroitin sulfate (CS) glycosaminoglycans inhibit regeneration in the adult central nervous system (CNS). We report here that...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cultured cells: mouse E17 cortical neurons
Citation Extract:
Paveliev M, Fenrich KK, Kislin M, Kuja-Panula J, Kulesskiy E, Varjosalo M, Kajander T, Mugantseva E, Ahonen-Bishopp A, Khiroug L, Kulesskaya N, Rougon G, Rauvala H. HB-GAM (pleiotrophin) reverses inhibition of neural regeneration by the CNS extracellular matrix. Sci Rep. 2016;6:33916. doi:10.1038/srep33916.

Flow-dependent YAP/TAZ activities regulate endothelial phenotypes and atherosclerosis

Authors:
Wang K-C, Yeh Y-T, Nguyen P, Limqueco E, Lopez J, Thorossian S, Guan K-L, Li Y-SJ, Chien S
Citation:
Proc Nat Acad Sci USA. 2016;[Epub ahead of print] doi:10.1073/pnas.1613121113
Epub:
Yes
Abstract:
The focal nature of atherosclerotic lesions suggests an important role of local hemodynamic environment. Recent studies have...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Wang K-C, Yeh Y-T, Nguyen P, Limqueco E, Lopez J, Thorossian S, Guan K-L, Li Y-SJ, Chien S. Flow-dependent YAP/TAZ activities regulate endothelial phenotypes and atherosclerosis. Proc Nat Acad Sci USA. 2016;[Epub ahead of print] doi:10.1073/pnas.1613121113.

Phosphorylation of Def Regulates Nucleolar p53 Turnover and Cell Cycle Progression through Def Recruitment of Calpain3

Authors:
Guan Y, Huang D, Chen F, Gao C, Tao T, Shi H, Zhao S, Liao Z, Lo LJ, Wang Y, Chen J, Peng J
Citation:
PLoS Biol. 2016;14(9):e1002555. doi:10.1371/journal.pbio.1002555
Epub:
Not Epub
Abstract:
Digestive organ expansion factor (Def) is a nucleolar protein that plays dual functions: it serves as a component of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guan Y, Huang D, Chen F, Gao C, Tao T, Shi H, Zhao S, Liao Z, Lo LJ, Wang Y, Chen J, Peng J. Phosphorylation of Def Regulates Nucleolar p53 Turnover and Cell Cycle Progression through Def Recruitment of Calpain3. PLoS Biol. 2016;14(9):e1002555. doi:10.1371/journal.pbio.1002555.

See-Thru-Gonad zebrafish line: developmental and functional validation

Authors:
Presslauer C, Bizuayehu TT, Razmi K, Fernandes JM, Babiak I
Citation:
Reproduction. 2016 Nov;152(5):507-17. doi: 10.1530/REP-16-0328
Epub:
Not Epub
Abstract:
Zebrafish are an important model species in developmental biology. However, their potential in reproductive biology research...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Presslauer C, Bizuayehu TT, Razmi K, Fernandes JM, Babiak I. See-Thru-Gonad zebrafish line: developmental and functional validation. Reproduction. 2016 Nov;152(5):507-17. doi: 10.1530/REP-16-0328.

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