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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

AHR2 morpholino knockdown reduces the toxicity of total particulate matter to zebrafish embryos

Authors:
Massarsky A, Bone AJ, Dong W, Hinton DE, Prasad GL, Di Giulio RT
Citation:
Toxicol Appl Pharmacol. 2016 Aug 26. pii: S0041-008X(16)30247-2. doi: 10.1016/j.taap.2016.08.024. [Epub ahead of print]
Epub:
Yes
Abstract:
The zebrafish embryo has been proposed as a 'bridge model' to study the effects of cigarette smoke on early...
Link:
http://www.sciencedirect.com/science/article/pii/S0041008X16302472
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Massarsky A, Bone AJ, Dong W, Hinton DE, Prasad GL, Di Giulio RT. AHR2 morpholino knockdown reduces the toxicity of total particulate matter to zebrafish embryos. Toxicol Appl Pharmacol. 2016 Aug 26. pii: S0041-008X(16)30247-2. doi: 10.1016/j.taap.2016.08.024. [Epub ahead of print].

Effective Synthesis of Fluorescently Labeled Morpholino Nucleoside Triphosphate Derivatives

Authors:
Tarasenko YV, Abramova TV, Mamatuk VI, Silnikov VN
Citation:
Nucleosides Nucleotides Nucleic Acids. 2016;35(1):32-42. doi: 10.1080/15257770.2015.1114125. Epub 2016 Jan 25
Epub:
Not Epub
Abstract:
Morpholino nucleoside triphosphates (A, U, G, C, T) bearing the active functional amino group tethered to morpholine residue...
Link:
http://www.tandfonline.com/doi/abs/10.1080/15257770.2015.1114125
Citation Extract:
Tarasenko YV, Abramova TV, Mamatuk VI, Silnikov VN. Effective Synthesis of Fluorescently Labeled Morpholino Nucleoside Triphosphate Derivatives. Nucleosides Nucleotides Nucleic Acids. 2016;35(1):32-42. doi: 10.1080/15257770.2015.1114125. Epub 2016 Jan 25.

Regulation of Vegf signaling by natural and synthetic ligands

Authors:
Rossi A, Gauvrit S, Marass M, Pan L, Moens CB, Stainier DY
Citation:
Blood. 2016 Aug 24. pii: blood-2016-04-711192. [Epub ahead of print]
Epub:
Yes
Abstract:
The mechanisms that allow cells to bypass anti-VEGFA therapy remain poorly understood. Here we use zebrafish to investigate...
Link:
http://www.bloodjournal.org/content/early/2016/08/24/blood-2016-04-711192
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rossi A, Gauvrit S, Marass M, Pan L, Moens CB, Stainier DY. Regulation of Vegf signaling by natural and synthetic ligands. Blood. 2016 Aug 24. pii: blood-2016-04-711192. [Epub ahead of print].

Identification of novel regulators of developmental hematopoiesis using endoglin regulatory elements as molecular probes

Authors:
Nasrallah R, Fast EM, Solaimani P, Knezevic K, Eliades A, Patel R, Thambyrajah R, Unnikrishnan A, Thoms J, Beck D, Vink CS, Smith A, Wong J, Shepherd M, Kent D, Roychoudhuri R, Paul F, Klippert J, Hammes A, Willnow T, Göttgens B, Dzierzak E, Zon LI, Lacaud G, Kouskoff V, Pimanda JE
Citation:
Blood. 2016 Aug 23. pii: blood-2016-02-697870. [Epub ahead of print]
Epub:
Yes
Abstract:
Enhancers are the primary determinants of cell identity and specific promoter/enhancer combinations of Endoglin (ENG) have been...
Link:
http://www.bloodjournal.org/content/early/2016/08/23/blood-2016-02-697870
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nasrallah R, Fast EM, Solaimani P, Knezevic K, Eliades A, Patel R, Thambyrajah R, Unnikrishnan A, Thoms J, Beck D, Vink CS, Smith A, Wong J, Shepherd M, Kent D, Roychoudhuri R, Paul F, Klippert J, Hammes A, Willnow T, Göttgens B, Dzierzak E, Zon LI, Lacaud G, Kouskoff V, Pimanda JE. Identification of novel regulators of developmental hematopoiesis using endoglin regulatory elements as molecular probes. Blood. 2016 Aug 23. pii: blood-2016-02-697870. [Epub ahead of print].

PIK3C2B inhibition improves function and prolongs survival in myotubular myopathy animal models

Authors:
Sabha N, Volpatti JR, Gonorazky H, Reifler A, Davidson AE, Li X, Eltayeb NM, Dall'Armi C, Di Paolo G, Brooks SV, Buj-Bello A, Feldman EL, Dowling JJ
Citation:
J Clin Invest. 2016 Aug 22. pii: 86841. doi: 10.1172/JCI86841. [Epub ahead of print]
Epub:
Yes
Abstract:
Myotubular myopathy (MTM) is a devastating pediatric neuromuscular disorder of phosphoinositide (PIP) metabolism resulting from...
Link:
https://www.jci.org/articles/view/86841
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sabha N, Volpatti JR, Gonorazky H, Reifler A, Davidson AE, Li X, Eltayeb NM, Dall'Armi C, Di Paolo G, Brooks SV, Buj-Bello A, Feldman EL, Dowling JJ. PIK3C2B inhibition improves function and prolongs survival in myotubular myopathy animal models. J Clin Invest. 2016 Aug 22. pii: 86841. doi: 10.1172/JCI86841. [Epub ahead of print].

The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis

Authors:
Villa M, Crotta S, Dingwell KS, Hirst EM, Gialitakis M, Ahlfors H, Smith JC, Stockinger B, Wack A
Citation:
Nat Commun. 2016 Aug 24;7:12652. doi: 10.1038/ncomms12652
Epub:
Not Epub
Abstract:
Epithelia function as barriers against environmental insults and express the transcription factor aryl hydrocarbon receptor (...
Link:
http://www.nature.com/ncomms/2016/160824/ncomms12652/full/ncomms12652.html
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Villa M, Crotta S, Dingwell KS, Hirst EM, Gialitakis M, Ahlfors H, Smith JC, Stockinger B, Wack A. The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis. Nat Commun. 2016 Aug 24;7:12652. doi: 10.1038/ncomms12652.

Differential Nanos 2 protein stability results in selective germ cell accumulation in the sea urchin

Authors:
Oulhen N, Wessel GM
Citation:
Dev Biol. 2016 Jul 14. pii: S0012-1606(16)30012-4. doi: 10.1016/j.ydbio.2016.07.007. [Epub ahead of print]
Epub:
Yes
Abstract:
Nanos is a translational regulator required for the survival and maintenance of primordial germ cells. In the sea urchin,...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616300124
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin), Patiria miniata (starfish)
Citation Extract:
Oulhen N, Wessel GM. Differential Nanos 2 protein stability results in selective germ cell accumulation in the sea urchin. Dev Biol. 2016 Jul 14. pii: S0012-1606(16)30012-4. doi: 10.1016/j.ydbio.2016.07.007. [Epub ahead of print].

Hedgehog-dependent E3-ligase Midline1 regulates ubiquitin-mediated proteasomal degradation of Pax6 during visual system development

Authors:
Pfirrmann T, Jandt E, Ranft S, Lokapally A, Neuhaus H, Perron M, Hollemann T
Citation:
Proc Natl Acad Sci U S A. 2016 Aug 23. pii: 201600770. [Epub ahead of print]
Epub:
Yes
Abstract:
Pax6 is a key transcription factor involved in eye, brain, and pancreas development. Although pax6 is expressed in the whole...
Link:
http://www.pnas.org/content/early/2016/08/22/1600770113.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pfirrmann T, Jandt E, Ranft S, Lokapally A, Neuhaus H, Perron M, Hollemann T. Hedgehog-dependent E3-ligase Midline1 regulates ubiquitin-mediated proteasomal degradation of Pax6 during visual system development. Proc Natl Acad Sci U S A. 2016 Aug 23. pii: 201600770. [Epub ahead of print].

Neuromuscular NMDA Receptors Modulate Developmental Synapse Elimination

Authors:
Personius KE, Slusher BS, Udin SB
Citation:
J Neurosci. 2016 Aug 24;36(34):8783-9. doi: 10.1523/JNEUROSCI.1181-16.2016
Epub:
Not Epub
Abstract:
At birth, each mammalian skeletal muscle fiber is innervated by multiple motor neurons, but in a few weeks, all but one of...
Link:
http://www.jneurosci.org/content/36/34/8783.abstract
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Personius KE, Slusher BS, Udin SB. Neuromuscular NMDA Receptors Modulate Developmental Synapse Elimination. J Neurosci. 2016 Aug 24;36(34):8783-9. doi: 10.1523/JNEUROSCI.1181-16.2016.

Manduca Contactin Regulates Amyloid Precursor Protein-Dependent Neuronal Migration

Authors:
Ramaker JM, Swanson TL, Copenhaver PF
Citation:
J Neurosci. 2016 Aug 17;36(33):8757-75. doi: 10.1523/JNEUROSCI.0729-16.2016
Epub:
Not Epub
Abstract:
Amyloid precursor protein (APP) was originally identified as the source of β-amyloid peptides that accumulate in Alzheimer...
Link:
http://www.jneurosci.org/content/36/33/8757.abstract
Organism or Cell Type:
Manduca sexta (hawkmoth)
Citation Extract:
Ramaker JM, Swanson TL, Copenhaver PF. Manduca Contactin Regulates Amyloid Precursor Protein-Dependent Neuronal Migration. J Neurosci. 2016 Aug 17;36(33):8757-75. doi: 10.1523/JNEUROSCI.0729-16.2016.

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