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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction

Authors:
Elmonem MA, Khalil R, Khodaparast L, Khodaparast L, Arcolino FO, Morgan J, Pastore A, Tylzanowski P, Ny A, Lowe M, de Witte PA, Baelde HJ, van den Heuvel LP, Levtchenko E
Citation:
Sci Rep. 2017;7:42583. doi:10.1038/srep42583
Epub:
Not Epub
Abstract:
The human ubiquitous protein cystinosin is responsible for transporting the disulphide amino acid cystine from the lysosomal...
Link:
http://www.nature.com/articles/srep42583
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Elmonem MA, Khalil R, Khodaparast L, Khodaparast L, Arcolino FO, Morgan J, Pastore A, Tylzanowski P, Ny A, Lowe M, de Witte PA, Baelde HJ, van den Heuvel LP, Levtchenko E. Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction. Sci Rep. 2017;7:42583. doi:10.1038/srep42583.

Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling

Authors:
Han W, Lee H, Han J-K
Citation:
Sci Rep. 2017;7:42590 doi:10.1038/srep42590
Epub:
Not Epub
Abstract:
The Tcf/Lef family of transcription factors mediates the Wnt/β-catenin pathway that is involved in a wide range of biological...
Link:
http://www.nature.com/articles/srep42590
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Han W, Lee H, Han J-K. Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling. Sci Rep. 2017;7:42590 doi:10.1038/srep42590.

Dual roles of Akirin2 during Xenopus neural development

Authors:
Liu X, Xia Y, Tang J, Ma L, Li C, Ma P, Mao B
Citation:
J Biol Chem. 2017 Feb 13. pii: jbc.M117.777110. doi: 10.1074/jbc.M117.777110. [Epub ahead of print]
Epub:
Yes
Abstract:
To ensure correct spatial and temporal patterning, embryos must maintain pluripotent cell populations and control when cells...
Link:
http://www.jbc.org/content/early/2017/02/13/jbc.M117.777110.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Liu X, Xia Y, Tang J, Ma L, Li C, Ma P, Mao B. Dual roles of Akirin2 during Xenopus neural development. J Biol Chem. 2017 Feb 13. pii: jbc.M117.777110. doi: 10.1074/jbc.M117.777110. [Epub ahead of print].

Snail2 and Zeb2 repress P-Cadherin to define embryonic territories in the chick embryo

Authors:
Acloque H, Ocaña OH, Abad D, Stern CD, Nieto MA
Citation:
Development. 2017 Jan 13. pii: dev.142562. doi: 10.1242/dev.142562. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Snail and Zeb transcription factors induce epithelial to mesenchymal transition (EMT) in embryonic and adult tissues by direct...
Link:
http://dev.biologists.org/content/144/4/649.long
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Acloque H, Ocaña OH, Abad D, Stern CD, Nieto MA. Snail2 and Zeb2 repress P-Cadherin to define embryonic territories in the chick embryo. Development. 2017 Jan 13. pii: dev.142562. doi: 10.1242/dev.142562. [Epub ahead of print].

Analysis of Craniocardiac Malformations in Xenopus using Optical Coherence Tomography

Authors:
Deniz E, Jonas S, Hooper M, Griffin JN, Choma MA, Khokha MF
Citation:
Sci Rep. 2017;7:42506. doi:10.1038/srep42506
Epub:
Not Epub
Abstract:
Birth defects affect 3% of children in the United States. Among the birth defects, congenital heart disease and craniofacial...
Link:
http://www.nature.com/articles/srep42506
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Deniz E, Jonas S, Hooper M, Griffin JN, Choma MA, Khokha MF. Analysis of Craniocardiac Malformations in Xenopus using Optical Coherence Tomography. Sci Rep. 2017;7:42506. doi:10.1038/srep42506.

m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition

Authors:
Zhao BS, Wang X, Beadell AV, Lu Z, Shi H, Kuuspalu A, Ho RK, He C
Citation:
Nature. 2017 Feb 13. doi: 10.1038/nature21355. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The maternal-to-zygotic transition (MZT) is one of the most profound and tightly orchestrated processes during the early life...
Link:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature21355.html
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao BS, Wang X, Beadell AV, Lu Z, Shi H, Kuuspalu A, Ho RK, He C. m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition. Nature. 2017 Feb 13. doi: 10.1038/nature21355. [Epub ahead of print].

Cyp1b1 Regulates Ocular Fissure Closure Through a Retinoic Acid-Independent Pathway

Authors:
Williams AL, Eason J, Chawla B, Bohnsack BL
Citation:
Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1084-1097. doi: 10.1167/iovs.16-20235
Epub:
Not Epub
Abstract:
Purpose: Mutations in the CYP1B1 gene are the most commonly identified genetic causes of primary infantile-onset glaucoma....
Link:
http://iovs.arvojournals.org/article.aspx?articleid=2603905
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Williams AL, Eason J, Chawla B, Bohnsack BL. Cyp1b1 Regulates Ocular Fissure Closure Through a Retinoic Acid-Independent Pathway. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1084-1097. doi: 10.1167/iovs.16-20235.

Comparison of Zebrafish tmem88a mutant and morpholino knockdown phenotypes

Authors:
Eve AM, Place ES, Smith JC
Citation:
PLoS One. 2017 Feb 13;12(2):e0172227. doi: 10.1371/journal.pone.0172227
Epub:
Not Epub
Abstract:
Tmem88a is a transmembrane protein that is thought to be a negative regulator of the Wnt signalling pathway. Several groups...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172227
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Eve AM, Place ES, Smith JC. Comparison of Zebrafish tmem88a mutant and morpholino knockdown phenotypes. PLoS One. 2017 Feb 13;12(2):e0172227. doi: 10.1371/journal.pone.0172227.

The Neuropeptide Galanin Is Up-Regulated during Cholestasis and Contributes to Cholangiocyte Proliferation

Authors:
McMillin M, Frampton G, Grant S, DeMorrow S
Citation:
Am J Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2016.12.015
Epub:
Yes
Abstract:
During the course of cholestatic liver diseases, mitotically dormant cholangiocytes proliferate and subsequently acquire a...
Link:
http://ajp.amjpathol.org/article/S0002-9440(17)30065-2/abstract
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
rat
Citation Extract:
McMillin M, Frampton G, Grant S, DeMorrow S. The Neuropeptide Galanin Is Up-Regulated during Cholestasis and Contributes to Cholangiocyte Proliferation. Am J Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2016.12.015.

The small GTPase Arf6 regulates sea urchin morphogenesis

Authors:
Stepicheva NA, Dumas M, Kobi P, Donaldson JG, Song JL
Citation:
Differentiation. 2017 Feb 2;95:31-43. doi: 10.1016/j.diff.2017.01.003. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The small GTPase Arf6 is a conserved protein that is expressed in all metazoans. Arf6 remodels cytoskeletal actin and mediates...
Link:
http://www.sciencedirect.com/science/article/pii/S030146811630069X
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Stepicheva NA, Dumas M, Kobi P, Donaldson JG, Song JL. The small GTPase Arf6 regulates sea urchin morphogenesis. Differentiation. 2017 Feb 2;95:31-43. doi: 10.1016/j.diff.2017.01.003. [Epub ahead of print].

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