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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12165 scientific papers returned from the database with the search filters currently being used below.

A mutation in ADIPOR1 causes nonsyndromic autosomal dominant retinitis pigmentosa

Authors:
Zhang J, Wang C, Shen Y, Chen N, Wang L, Liang L, Guo T, Yin X, Ma Z, Zhang B, Yang L
Citation:
Hum Genet. 2016 Sep 21. [Epub ahead of print] doi:10.1007/s00439-016-1730-2
Epub:
Yes
Abstract:
Retinitis pigmentosa (RP) is a clinically and genetically heterogeneous disorder characterized by night blindness, visual field...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang J, Wang C, Shen Y, Chen N, Wang L, Liang L, Guo T, Yin X, Ma Z, Zhang B, Yang L. A mutation in ADIPOR1 causes nonsyndromic autosomal dominant retinitis pigmentosa. Hum Genet. 2016 Sep 21. [Epub ahead of print] doi:10.1007/s00439-016-1730-2.

PDGF signaling directs cardiomyocyte movement toward the midline during heart tube assembly

Authors:
Bloomekatz J, Singh R, Prall OWJ, Dunn AC, Vaughan M, Loo C-S, Harvey RP, Yelon D
Citation:
bioRxiv. 2016. doi:10.1101/076703
Epub:
Not Epub
Abstract:
Communication between neighboring tissues plays a central role in guiding organ morphogenesis. During heart tube assembly,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bloomekatz J, Singh R, Prall OWJ, Dunn AC, Vaughan M, Loo C-S, Harvey RP, Yelon D. PDGF signaling directs cardiomyocyte movement toward the midline during heart tube assembly. bioRxiv. 2016. doi:10.1101/076703.

Loss of ZNF32 augments the regeneration of nervous lateral line system through negative regulation of SOX2 transcription

Authors:
Wei Y, Li K, Yao S, Gao J, Li J, Shang Y, Zhang J, Zhang L, Li Y, Mo X, Meng W, Xiang R, Hu J, Lin P, Wei Y
Citation:
Oncotarget. 2016 Sep 8. doi: 10.18632/oncotarget.11895. [Epub ahead of print]
Epub:
Yes
Abstract:
Human zinc finger protein 32 (ZNF32) is a Cys2-His2 zinc-finger transcription factor that plays an important role in cell fate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei Y, Li K, Yao S, Gao J, Li J, Shang Y, Zhang J, Zhang L, Li Y, Mo X, Meng W, Xiang R, Hu J, Lin P, Wei Y. Loss of ZNF32 augments the regeneration of nervous lateral line system through negative regulation of SOX2 transcription. Oncotarget. 2016 Sep 8. doi: 10.18632/oncotarget.11895. [Epub ahead of print].

Preparation of Cell Lysate from Mouse Oocytes for Western Blotting Analysis

Authors:
Marangos P
Citation:
Methods Mol Biol. 2016;1457:209-15. doi: 10.1007/978-1-4939-3795-0_15
Epub:
Not Epub
Abstract:
Western Blotting has been used extensively for the identification of the protein factors that regulate mammalian oocyte meiosis...
Organism or Cell Type:
mouse oocyte
Citation Extract:
Marangos P. Preparation of Cell Lysate from Mouse Oocytes for Western Blotting Analysis. Methods Mol Biol. 2016;1457:209-15. doi: 10.1007/978-1-4939-3795-0_15.

The E3 ubiquitin ligase Hace1 is required for early embryonic development in Xenopus laevis

Authors:
Iimura A, Yamazaki F, Suzuki T, Endo T, Nishida E, Kusakabe M
Citation:
BMC Dev Biol. 2016;16:31. doi:10.1186/s12861-016-0132-y
Epub:
Not Epub
Abstract:
Background: HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (HACE1) regulates a wide variety of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Iimura A, Yamazaki F, Suzuki T, Endo T, Nishida E, Kusakabe M. The E3 ubiquitin ligase Hace1 is required for early embryonic development in Xenopus laevis. BMC Dev Biol. 2016;16:31. doi:10.1186/s12861-016-0132-y.

Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair

Authors:
Middel V, Zhou L, Takamiya M, Beil T, Shahid M, Roostalu U, Grabher C, Rastegar S, Reischl M, Nienhaus GU, Strähle U
Citation:
Nat Commun. 2016 Sep 19;7:12875. doi: 10.1038/ncomms12875
Epub:
Not Epub
Abstract:
Failure to repair the sarcolemma leads to muscle cell death, depletion of stem cells and myopathy. Hence, membrane lesions are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Middel V, Zhou L, Takamiya M, Beil T, Shahid M, Roostalu U, Grabher C, Rastegar S, Reischl M, Nienhaus GU, Strähle U. Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair. Nat Commun. 2016 Sep 19;7:12875. doi: 10.1038/ncomms12875.

Mechanosensing is critical for axon growth in the developing brain

Authors:
Koser DE, Thompson AJ, Foster SK, Dwivedy A, Pillai EK, Sheridan GK, Svoboda H, Viana M, Costa LD, Guck J, Holt CE, Franze K
Citation:
Nat Neurosci. 2016 Sep 19. doi: 10.1038/nn.4394. [Epub ahead of print]
Epub:
Yes
Abstract:
During nervous system development, neurons extend axons along well-defined pathways. The current understanding of axon...
Organism or Cell Type:
Xenopus
Citation Extract:
Koser DE, Thompson AJ, Foster SK, Dwivedy A, Pillai EK, Sheridan GK, Svoboda H, Viana M, Costa LD, Guck J, Holt CE, Franze K. Mechanosensing is critical for axon growth in the developing brain. Nat Neurosci. 2016 Sep 19. doi: 10.1038/nn.4394. [Epub ahead of print].

Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis

Authors:
Walentek P, Quigley IK, Sun DI, Sajjan UK, Kintner C, Harland RM
Citation:
Elife. 2016 Sep 13;5. pii: e17557. doi: 10.7554/eLife.17557. [Epub ahead of print]
Epub:
Yes
Abstract:
Upon cell cycle exit, centriole-to-basal body transition facilitates cilia formation. The centriolar protein Cp110 is a...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Walentek P, Quigley IK, Sun DI, Sajjan UK, Kintner C, Harland RM. Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis. Elife. 2016 Sep 13;5. pii: e17557. doi: 10.7554/eLife.17557. [Epub ahead of print].

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition

Authors:
Dahl JA, Jung I, Aanes H, Greggains GD, Manaf A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bjørås M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A
Citation:
Nature. 2016 Sep 14. doi: 10.1038/nature19360. [Epub ahead of print]
Epub:
Yes
Abstract:
Maternal-to-zygotic transition (MZT) is essential for the formation of a new individual, but is still poorly understood despite...
Organism or Cell Type:
mouse oocyte
Citation Extract:
Dahl JA, Jung I, Aanes H, Greggains GD, Manaf A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bjørås M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A. Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition. Nature. 2016 Sep 14. doi: 10.1038/nature19360. [Epub ahead of print].

Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy

Authors:
Ayhan DH, Tamer YT, Akbar M, Bailey SM, Wong M, Daly SM, Greenberg DE, Toprak E
Citation:
PLoS Biol. 2016 Sep 15;14(9):e1002552. doi: 10.1371/journal.pbio.1002552. eCollection 2016 Sep
Epub:
Not Epub
Abstract:
The lack of effective and well-tolerated therapies against antibiotic-resistant bacteria is a global public health problem...
Delivery Method:
Peptide-linked
Organism or Cell Type:
cell culture: Escherichia coli, Klebsiella pneumoniae, Salmonella enterica, Acinetobacter baumannii, Pseudomonas aeruginosa, Burkholderia cenocepacia
Citation Extract:
Ayhan DH, Tamer YT, Akbar M, Bailey SM, Wong M, Daly SM, Greenberg DE, Toprak E. Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy. PLoS Biol. 2016 Sep 15;14(9):e1002552. doi: 10.1371/journal.pbio.1002552. eCollection 2016 Sep.

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