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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Congenital myopathy results from misregulation of a muscle Ca2+ channel by mutant Stac3
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Citation:
Proc Natl Acad Sci U S A. 2016 Dec 21. pii: 201619238. doi: 10.1073/pnas.1619238114. [Epub ahead of print] Epub:
Yes Abstract:
Skeletal muscle contractions are initiated by an increase in Ca2+ released during excitation-contraction (EC) coupling, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Linsley JW, Hsu IU, Groom L, Yarotskyy V, Lavorato M, Horstick EJ, Linsley D, Wang W, Franzini-Armstrong C, Dirksen RT, Kuwada JY. Congenital myopathy results from misregulation of a muscle Ca2+ channel by mutant Stac3. Proc Natl Acad Sci U S A. 2016 Dec 21. pii: 201619238. doi: 10.1073/pnas.1619238114. [Epub ahead of print]. |
The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation
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Citation:
Sci Rep. 2016 Dec;6(1):22. doi: 10.1038/s41598-016-0030-3 Epub:
Not Epub Abstract:
Cytoplasmic dynein 1 is a multi-protein intracellular motor essential for mediating several mitotic functions, including the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mahale S, Kumar M, Sharma A, Babu A, Ranjan S, Sachidanandan C, Mylavarapu SV. The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation. Sci Rep. 2016 Dec;6(1):22. doi: 10.1038/s41598-016-0030-3. |
HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels
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Citation:
Nat Commun. 2016 Dec 22;7:13889. doi: 10.1038/ncomms13889 Epub:
Not Epub Abstract:
A fundamental question is how autophagosome formation is regulated. Here we show that the PX domain protein HS1BP3 is a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A. HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels. Nat Commun. 2016 Dec 22;7:13889. doi: 10.1038/ncomms13889. |
Transcriptome Profiling Identifies Ribosome Biogenesis as a Target of Alcohol Teratogenicity and Vulnerability during Early Embryogenesis
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Citation:
PLoS ONE. 2017;12(1):e0169351. doi:10.1371/journal.pone.0169351 Epub:
Not Epub Abstract:
Fetal alcohol spectrum disorder (FASD) is a leading cause of neurodevelopmental disability. Individuals with FASD may exhibit a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Berres ME, Garic A, Flentke GR, Smith SM. Transcriptome Profiling Identifies Ribosome Biogenesis as a Target of Alcohol Teratogenicity and Vulnerability during Early Embryogenesis. PLoS ONE. 2017;12(1):e0169351. doi:10.1371/journal.pone.0169351. |
Transient Inhibition of Endogenous Transforming Growth Factor- β1 (TGFβ1) in Hematopoietic Stem Cells Accelerates Engraftment and Enhances Multi-Lineage Repopulating Efficiency
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Citation:
J Stem Cell Res Ther. 2016;1(7):00045. doi:10.15406/jsrt.2016.01.00045 Epub:
Not Epub Abstract:
We show that ex vivo transient inhibition of endogenous transforming growth factor-β1 (TGFβ1) in highly enriched and partially... Organism or Cell Type:
mouse with ex-vivo-treatment & return: Long Term Repopulating-Hematopoietic Stem Cells Citation Extract: Bartelmez S, Storey C, Iversen P, Ruscetti F. Transient Inhibition of Endogenous Transforming Growth Factor- β1 (TGFβ1) in Hematopoietic Stem Cells Accelerates Engraftment and Enhances Multi-Lineage Repopulating Efficiency. J Stem Cell Res Ther. 2016;1(7):00045. doi:10.15406/jsrt.2016.01.00045. |
Blood flow directs arterial-venous remodeling through Notch activation and endothelial cell migration
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Citation:
bioRxiv. 2016. doi:10.1101/095307 Epub:
Yes Abstract:
Arteries and veins are lined by arterial and venous endothelial cells (ECs), which are functionally distinct. During embryonic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Weijts B, Gutierrez E, Saikin SK, Ablooglu AJ, Traver D, Groisman A, Tkachenko E. Blood flow directs arterial-venous remodeling through Notch activation and endothelial cell migration. bioRxiv. 2016. doi:10.1101/095307. |
RNA activation of haploinsufficient Foxg1 gene in murine neocortex
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Citation:
Sci Rep. 2016 Dec 20;6:39311. doi: 10.1038/srep39311 Epub:
Not Epub Abstract:
More than one hundred distinct gene hemizygosities are specifically linked to epilepsy, mental retardation, autism,... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: NIH/3T3 Citation Extract: Fimiani C, Goina E, Su Q, Gao G, Mallamaci A. RNA activation of haploinsufficient Foxg1 gene in murine neocortex. Sci Rep. 2016 Dec 20;6:39311. doi: 10.1038/srep39311. |
Prostaglandin signaling regulates nephron segment patterning of renal progenitors during zebrafish kidney development
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Citation:
Elife. 2016 Dec 20;5. pii: e17551. doi: 10.7554/eLife.17551 Epub:
Not Epub Abstract:
Kidney formation involves patterning events that induce renal progenitors to form nephrons with an intricate composition of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Poureetezadi SJ, Cheng CN, Chambers JM, Drummond BE, Wingert RA. Prostaglandin signaling regulates nephron segment patterning of renal progenitors during zebrafish kidney development. Elife. 2016 Dec 20;5. pii: e17551. doi: 10.7554/eLife.17551. |
Visual Experience Dependent Regulation of Neuronal Structure and Function by Histone Deacetylase 1 in Developing Xenopus Tectum in vivo
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Citation:
Dev Neurobiol. 2016 Dec 29. doi: 10.1002/dneu.22480. [Epub ahead of print] Epub:
Not Epub Abstract:
Histone deacetylase 1 (HDAC1) is thought to play pivotal roles in neurogenesis and neurodegeneration. However, the role of... Organism or Cell Type:
Xenopus Citation Extract: Ruan H, Gao J, Qi X, Tao Y, Guo X, Guo Z, Zheng L, Song Y, Liao Y, Shen W. Visual Experience Dependent Regulation of Neuronal Structure and Function by Histone Deacetylase 1 in Developing Xenopus Tectum in vivo. Dev Neurobiol. 2016 Dec 29. doi: 10.1002/dneu.22480. [Epub ahead of print]. |
Impairment of cargo transportation due to gbf1 mutation disrupts vascular integrity and causes hemorrhage in zebrafish embryos
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Citation:
J Biol Chem. 2016 Dec 21. pii: jbc.M116.767608. doi: 10.1074/jbc.M116.767608. [Epub ahead of print] Epub:
Yes Abstract:
ADP-ribosylation factor (ARF) GTPases are activated by guanine nucleotide exchange factors including Golgi Brefeldin A-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen J, Wu X, Yao L, Yan L, Zhang L, Qiu J, Liu X, Jia S, Meng A. Impairment of cargo transportation due to gbf1 mutation disrupts vascular integrity and causes hemorrhage in zebrafish embryos. J Biol Chem. 2016 Dec 21. pii: jbc.M116.767608. doi: 10.1074/jbc.M116.767608. [Epub ahead of print]. |