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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Exon 53 skipping of the dystrophin gene in patients with Duchenne muscular dystrophy by systemic administration of NS-065/NCNP-01: A phase 1, dose escalation, first-in-human study

Authors:
Komaki H, Nagata T, Saito T, Masuda S, Takeshita E, Tachimori H, Sasaki M, Takeda S
Citation:
Neuromusc Disord. 2015;26(2)S261-2 doi:10.1016/j.nmd.2015.06.276
Epub:
Not Epub
Abstract:
Antisense oligonucleotide-induced exon skipping, which is being studied for the treatment of Duchenne muscular dystrophy (DMD...
Link:
http://www.nmd-journal.com/article/S0960-8966(15)00457-5/abstract
Organism or Cell Type:
human
Citation Extract:
Komaki H, Nagata T, Saito T, Masuda S, Takeshita E, Tachimori H, Sasaki M, Takeda S. Exon 53 skipping of the dystrophin gene in patients with Duchenne muscular dystrophy by systemic administration of NS-065/NCNP-01: A phase 1, dose escalation, first-in-human study. Neuromusc Disord. 2015;26(2)S261-2 doi:10.1016/j.nmd.2015.06.276.

A transcription factor network controls cell migration and fate decisions in the developing zebrafish pineal complex

Authors:
Khuansuwan S, Clanton JA, Dean BJ, Patton JG, Gamse JT
Citation:
Development. 2016 Jun 17. pii: dev.131680. [Epub ahead of print]
Epub:
Yes
Abstract:
The zebrafish pineal complex consists of four cell types (rod and cone photoreceptors, projection neurons, and parapineal...
Link:
http://dev.biologists.org/content/143/14/2641.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Khuansuwan S, Clanton JA, Dean BJ, Patton JG, Gamse JT. A transcription factor network controls cell migration and fate decisions in the developing zebrafish pineal complex. Development. 2016 Jun 17. pii: dev.131680. [Epub ahead of print].

Alk1 controls arterial endothelial cell migration in lumenized vessels

Authors:
Rochon ER, Menon PG, Roman BL
Citation:
Development. 2016 Jun 10. pii: dev.135392. [Epub ahead of print]
Epub:
Yes
Abstract:
Heterozygous loss of the arterial-specific TGF-β type I receptor, activin receptor-like kinase 1 (ALK1), causes hereditary...
Link:
http://dev.biologists.org/content/143/14/2593.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rochon ER, Menon PG, Roman BL. Alk1 controls arterial endothelial cell migration in lumenized vessels. Development. 2016 Jun 10. pii: dev.135392. [Epub ahead of print].

The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling

Authors:
Kwan W, Cortes M, Frost I, Esain V, Theodore LN, Liu SY, Budrow N, Goessling W, North TE.
Citation:
Cell Stem Cell. 2016;[Epub] doi:10.1016/j.stem.2016.06.004
Epub:
Yes
Abstract:
Hematopoietic stem and progenitor cell (HSPC) specification is regulated by numerous defined factors acting locally within the...
Link:
http://www.cell.com/cell-stem-cell/abstract/S1934-5909(16)30154-0
Citation Extract:
Kwan W, Cortes M, Frost I, Esain V, Theodore LN, Liu SY, Budrow N, Goessling W, North TE.. The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling. Cell Stem Cell. 2016;[Epub] doi:10.1016/j.stem.2016.06.004.

New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections

Authors:
McPhillie M, Zhou Y, El Bissati K, Dubey J, Lorenzi H, Capper M, Lukens AK, Hickman M, Muench S, Verma SK, Weber CR, Wheeler K, Gordon J, Sanders J, Moulton H, Wang K, Kim TK, He Y, Santos T, Woods S, Lee P, Donkin D, Kim E, Fraczek L, Lykins J, Esaa F, Alibana-Clouser F, Dovgin S, Weiss L, Brasseur G, Wirth D, Kent M, Hood L, Meunieur B, Roberts CW, Hasnain SS, Antonyuk SV, Fishwick C, McLeod R
Citation:
Sci Rep. 2016 Jul 14;6:29179. doi: 10.1038/srep29179
Epub:
Not Epub
Abstract:
Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifetimes, can progressively...
Link:
http://www.nature.com/articles/srep29179
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: Toxoplasma gondii, RH-YFP tachyzoites and EGS^S14 bradyzoites
Citation Extract:
McPhillie M, Zhou Y, El Bissati K, Dubey J, Lorenzi H, Capper M, Lukens AK, Hickman M, Muench S, Verma SK, Weber CR, Wheeler K, Gordon J, Sanders J, Moulton H, Wang K, Kim TK, He Y, Santos T, Woods S, Lee P, Donkin D, Kim E, Fraczek L, Lykins J, Esaa F, Alibana-Clouser F, Dovgin S, Weiss L, Brasseur G, Wirth D, Kent M, Hood L, Meunieur B, Roberts CW, Hasnain SS, Antonyuk SV, Fishwick C, McLeod R. New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections. Sci Rep. 2016 Jul 14;6:29179. doi: 10.1038/srep29179.

Discovering miRNA Regulatory Networks in Holt–Oram Syndrome Using a Zebrafish Model

Authors:
D’Aurizio R, Russo F, Chiavacci E, Baumgart M, Groth M, D’Onofrio M, Arisi I, Rainaldi G, Pitto L, Pellegrini M
Citation:
Front Bioeng Biotechnol. 2016;doi:10.3389/fbioe.2016.00060
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are small non-coding RNAs that play an important role in the post-transcriptional regulation of gene...
Link:
http://journal.frontiersin.org/article/10.3389/fbioe.2016.00060/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
D’Aurizio R, Russo F, Chiavacci E, Baumgart M, Groth M, D’Onofrio M, Arisi I, Rainaldi G, Pitto L, Pellegrini M. Discovering miRNA Regulatory Networks in Holt–Oram Syndrome Using a Zebrafish Model. Front Bioeng Biotechnol. 2016;doi:10.3389/fbioe.2016.00060.

Formation of a “Pre-mouth Array” from the Extreme Anterior Domain Is Directed by Neural Crest and Wnt/PCP Signaling

Authors:
Jacox L, Chen J, Rothman A, Lathrop-Marshall H, Sive H
Citation:
Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.06.073
Epub:
Yes
Abstract:
The mouth arises from the extreme anterior domain (EAD), a region where the ectoderm and endoderm are directly juxtaposed. Here...
Link:
http://www.cell.com/cell-reports/fulltext/S2211-1247(16)30842-7
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Jacox L, Chen J, Rothman A, Lathrop-Marshall H, Sive H. Formation of a “Pre-mouth Array” from the Extreme Anterior Domain Is Directed by Neural Crest and Wnt/PCP Signaling. Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.06.073.

Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects

Authors:
Simon AJ, Lev A, Zhang Y, Weiss B, Rylova A, Eyal E, Kol N, Bare O, Cesarkas K, Soudack M, Greenberg-Kushnir N, Rhodes M, Wiest DL, Schiby G, Barshack I, Katz S, Pras E, Poran H, Reznik-Wolf H, Ribakovsky E, Simon C, Hazou W, Sidi Y, Lahad A, Katzir H, Sagie S, Aqeilan HA, Glousker G, Amariglio N, Tzfati Y, Selig S, Rechavi G, Somech R
Citation:
J Exp Med. 2016;[Epub ahead of print] doi:10.1084/jem.20151618
Epub:
Yes
Abstract:
The analysis of individuals with telomere defects may shed light on the delicate interplay of factors controlling genome...
Link:
http://jem.rupress.org/content/early/2016/07/13/jem.20151618.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Simon AJ, Lev A, Zhang Y, Weiss B, Rylova A, Eyal E, Kol N, Bare O, Cesarkas K, Soudack M, Greenberg-Kushnir N, Rhodes M, Wiest DL, Schiby G, Barshack I, Katz S, Pras E, Poran H, Reznik-Wolf H, Ribakovsky E, Simon C, Hazou W, Sidi Y, Lahad A, Katzir H, Sagie S, Aqeilan HA, Glousker G, Amariglio N, Tzfati Y, Selig S, Rechavi G, Somech R. Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects. J Exp Med. 2016;[Epub ahead of print] doi:10.1084/jem.20151618.

Developmental Apoptosis Mediates Entry and Positioning of Microglia in the Zebrafish Brain

Authors:
Casano AM, Albert M, Peri F
Citation:
Cell Rep. 2016;16;1–10. doi:10.1016/j.celrep.2016.06.033
Epub:
Not Epub
Abstract:
In the brain, neurons that fail to assemble into functional circuits are eliminated. Their clearance depends on microglia,...
Link:
http://www.cell.com/cell-reports/fulltext/S2211-1247(16)30773-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Casano AM, Albert M, Peri F. Developmental Apoptosis Mediates Entry and Positioning of Microglia in the Zebrafish Brain. Cell Rep. 2016;16;1–10. doi:10.1016/j.celrep.2016.06.033.

ANKS3 is mutated in a family with autosomal recessive laterality defect

Authors:
Shamseldin HE, Yakulov TA, Hashem A, Walz G, Alkuraya FS
Citation:
Hum Genet. 2016 Jul 14. [Epub ahead of print]
Epub:
Yes
Abstract:
Laterality defects are heterogeneous groups of congenital malformations that arise from perturbed asymmetrical development of...
Link:
http://link.springer.com/article/10.1007%2Fs00439-016-1712-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shamseldin HE, Yakulov TA, Hashem A, Walz G, Alkuraya FS. ANKS3 is mutated in a family with autosomal recessive laterality defect. Hum Genet. 2016 Jul 14. [Epub ahead of print].

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