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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development

Authors:
Zhang X, Liu X, Zhang M, Li T, Muth A, Thompson PA, Coonrod SA, Zhang X
Citation:
Sci Rep. 2016:6:38727. doi:10.1038/srep38727
Epub:
Not Epub
Abstract:
Peptidylarginine deiminase (PADI) enzymes are increasingly being associated with the regulation of chromatin structure and gene...
Link:
http://www.nature.com/articles/srep38727
Delivery Method:
microinjection
Organism or Cell Type:
mouse zygotes
Citation Extract:
Zhang X, Liu X, Zhang M, Li T, Muth A, Thompson PA, Coonrod SA, Zhang X. Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development. Sci Rep. 2016:6:38727. doi:10.1038/srep38727.

Glut1/SLC2A1 is crucial for the development of the blood-brain barrier in vivo

Authors:
Zheng PP, Romme E, van der Spek PJ, Dirven CM, Willemsen R, Kros JM
Citation:
Ann Neurol. 2010 Dec;68(6):835-44. doi: 10.1002/ana.22318
Epub:
Not Epub
Abstract:
OBJECTIVE: The overall permeability of the blood-brain barrier (BBB) is regulated by specialized cerebral endothelial cells and...
Link:
http://onlinelibrary.wiley.com/wol1/doi/10.1002/ana.22318/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zheng PP, Romme E, van der Spek PJ, Dirven CM, Willemsen R, Kros JM. Glut1/SLC2A1 is crucial for the development of the blood-brain barrier in vivo. Ann Neurol. 2010 Dec;68(6):835-44. doi: 10.1002/ana.22318.

Overexpression of TGF-β Inducible microRNA-143 in Zebrafish Leads to Impairment of the Glomerular Filtration Barrier by Targeting Proteoglycans

Authors:
Müller-Deile J, Gellrich F, Schenk H, Schroder P, Nyström J, Lorenzen J, Haller H, Schiffer M
Citation:
Cell Physiol Biochem. 2016;40(5):819-30. doi:10.1159/000453142
Epub:
Not Epub
Abstract:
Background: TGF-β is known as an important stress factor of podocytes in glomerular diseases. Apart from activation of direct...
Link:
http://www.karger.com/Article/FullText/453142
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Müller-Deile J, Gellrich F, Schenk H, Schroder P, Nyström J, Lorenzen J, Haller H, Schiffer M. Overexpression of TGF-β Inducible microRNA-143 in Zebrafish Leads to Impairment of the Glomerular Filtration Barrier by Targeting Proteoglycans. Cell Physiol Biochem. 2016;40(5):819-30. doi:10.1159/000453142.

In Vivo Visualization of Cardiomyocyte Apicobasal Polarity Reveals Epithelial to Mesenchymal-like Transition during Cardiac Trabeculation

Authors:
Jiménez-Amilburu V, Rasouli SJ, Staudt DW, Nakajima H, Chiba A, Mochizuki N, Stainier DYR
Citation:
Cell Rep. 2016;17:2687-99. doi:10.1016/j.celrep.2016.11.023
Epub:
Not Epub
Abstract:
Despite great strides in understanding cardiac trabeculation, many mechanistic aspects remain unclear. To elucidate how...
Link:
www.cell.com/cell-reports/pdf/S2211-1247(16)31581-9.pdf
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jiménez-Amilburu V, Rasouli SJ, Staudt DW, Nakajima H, Chiba A, Mochizuki N, Stainier DYR. In Vivo Visualization of Cardiomyocyte Apicobasal Polarity Reveals Epithelial to Mesenchymal-like Transition during Cardiac Trabeculation. Cell Rep. 2016;17:2687-99. doi:10.1016/j.celrep.2016.11.023.

cMyc Regulates the Size of the Premigratory Neural Crest Stem Cell Pool

Authors:
Kerosuo L, Bronner ME
Citation:
Cell Rep. 2016;17:2648-59. doi:10.1016/j.celrep.2016.11.025
Epub:
Not Epub
Abstract:
The neural crest is a transient embryonic population that originates within the central nervous system (CNS) and then migrates...
Link:
www.cell.com/cell-reports/pdf/S2211-1247(16)31583-2.pdf
Delivery Method:
injection then electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Kerosuo L, Bronner ME. cMyc Regulates the Size of the Premigratory Neural Crest Stem Cell Pool. Cell Rep. 2016;17:2648-59. doi:10.1016/j.celrep.2016.11.025.

Tbx20 Is an Essential Regulator of Embryonic Heart Growth in Zebrafish

Authors:
Just S, Raphel L, Berger IM, Bühler A, Keßler M, Rottbauer W
Citation:
PLoS One. 2016 Dec 1;11(12):e0167306. doi: 10.1371/journal.pone.0167306
Epub:
Not Epub
Abstract:
The molecular mechanisms that regulate cardiomyocyte proliferation during embryonic heart growth are not completely deciphered...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167306
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Just S, Raphel L, Berger IM, Bühler A, Keßler M, Rottbauer W. Tbx20 Is an Essential Regulator of Embryonic Heart Growth in Zebrafish. PLoS One. 2016 Dec 1;11(12):e0167306. doi: 10.1371/journal.pone.0167306.

Overexpression of Calr Mutants Perturbs Developmental Hematopoiesis in Zebrafish Embryos

Authors:
Lim K-H, Chang Y-C, Chiang Y-H, Lin H-C, Chang C-Y, Lin C-S, Huang L, Wang W-T, Chen CG-S, Chou W-C, Kuo Y-Y
Citation:
Blood. 2016;128:4282
Epub:
Not Epub
Abstract:
Introduction: Calreticulin (CALR) is a 46-kDa highly conserved, multicompartmental and multifunctional protein. CALR acts as a...
Link:
http://www.bloodjournal.org/content/128/22/4282
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lim K-H, Chang Y-C, Chiang Y-H, Lin H-C, Chang C-Y, Lin C-S, Huang L, Wang W-T, Chen CG-S, Chou W-C, Kuo Y-Y. Overexpression of Calr Mutants Perturbs Developmental Hematopoiesis in Zebrafish Embryos. Blood. 2016;128:4282.

ADAMTS13-/-zebrafish Model Created By Crispr/Cas Reveals a Novel Role of ADAMTS13 in Vascular Development and Prothrombotic Phenotype

Authors:
Zheng L, Zheng XL
Citation:
Blood. 2016;128:1446
Epub:
Not Epub
Abstract:
Background: Deficiency of plasma ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13),...
Link:
http://www.bloodjournal.org/content/128/22/1446
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zheng L, Zheng XL. ADAMTS13-/-zebrafish Model Created By Crispr/Cas Reveals a Novel Role of ADAMTS13 in Vascular Development and Prothrombotic Phenotype. Blood. 2016;128:1446.

Mural-Endothelial cell-cell interactions stabilize the developing zebrafish dorsal aorta

Authors:
Stratman AN, Pezoa SA, Farrelly OM, Castranova D, Dye LE III, Butler MG, Sidik H, Talbot WS, Weinstein BM
Citation:
Development. 2016;[Epub ahead of print] doi: 10.1242/dev.143131
Epub:
Yes
Abstract:
Mural cells (vascular smooth muscle cells and pericytes) play a critical role in the development of the vasculature, promoting...
Link:
http://dev.biologists.org/content/early/2016/12/01/dev.143131
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stratman AN, Pezoa SA, Farrelly OM, Castranova D, Dye LE III, Butler MG, Sidik H, Talbot WS, Weinstein BM. Mural-Endothelial cell-cell interactions stabilize the developing zebrafish dorsal aorta. Development. 2016;[Epub ahead of print] doi: 10.1242/dev.143131.

The guanine nucleotide exchange factor Net1 facilitates the specification of dorsal cell fates in zebrafish embryos by promoting maternal β-catenin activation

Authors:
Wei S, Dai M, Liu Z, Ma Y, Shang H, Cao Y, Wang Q
Citation:
Cell Res. 2016;[Epub ahead of print] doi:10.1038/cr.2016.141
Epub:
Yes
Abstract:
Wnt/β-catenin signaling is essential for the initiation of dorsal-ventral patterning during vertebrate embryogenesis. Maternal...
Link:
http://www.nature.com/cr/journal/vaop/ncurrent/full/cr2016141a.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei S, Dai M, Liu Z, Ma Y, Shang H, Cao Y, Wang Q. The guanine nucleotide exchange factor Net1 facilitates the specification of dorsal cell fates in zebrafish embryos by promoting maternal β-catenin activation. Cell Res. 2016;[Epub ahead of print] doi:10.1038/cr.2016.141.

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