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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

In vivo knockdown of FGFR2 and MET mRNA in trophectoderm of ovine conceptuses retards their development via abrogation of MAPK and MTOR pathways

Authors:
Wang X, Dunlap KA, Satterfield MC, Wu G, Bazer FW
Citation:
J Animal Sci. 2016;94(supp 5):376
Epub:
Not Epub
Abstract:
Wang X, Dunlap KA, Satterfield MC, Wu G, Bazer FW. In vivo knockdown of FGFR2 and MET mRNA in trophectoderm of ovine...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Ovis aries (sheep) conceptus
Citation Extract:
Wang X, Dunlap KA, Satterfield MC, Wu G, Bazer FW. In vivo knockdown of FGFR2 and MET mRNA in trophectoderm of ovine conceptuses retards their development via abrogation of MAPK and MTOR pathways. J Animal Sci. 2016;94(supp 5):376.

Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy

Authors:
Vila MC, Rayavarapu S, Hogarth MW, Van der Meulen JH, Horn A, Defour A, Takeda S, Brown KJ, Hathout Y, Nagaraju K, Jaiswal JK
Citation:
Cell Death Differ. 2016 Nov 11. doi: 10.1038/cdd.2016.127. [Epub ahead of print]
Epub:
Yes
Abstract:
Dystrophin deficiency is the genetic basis for Duchenne muscular dystrophy (DMD), but the cellular basis of progressive...
Delivery Method:
injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Vila MC, Rayavarapu S, Hogarth MW, Van der Meulen JH, Horn A, Defour A, Takeda S, Brown KJ, Hathout Y, Nagaraju K, Jaiswal JK. Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy. Cell Death Differ. 2016 Nov 11. doi: 10.1038/cdd.2016.127. [Epub ahead of print].

CFTR-β-catenin interaction regulates mouse embryonic stem cell differentiation and embryonic development

Authors:
Liu Z, Guo J, Wang Y, Weng Z, Huang B, Yu MK, Zhang X, Yuan P, Zhao H, Chan WY, Jiang X, Chan HC
Citation:
Cell Death Differ. 2016 Nov 11. doi: 10.1038/cdd.2016.118. [Epub ahead of print]
Epub:
Yes
Abstract:
Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-regulated anion channel capable of conducting both Cl- and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Liu Z, Guo J, Wang Y, Weng Z, Huang B, Yu MK, Zhang X, Yuan P, Zhao H, Chan WY, Jiang X, Chan HC. CFTR-β-catenin interaction regulates mouse embryonic stem cell differentiation and embryonic development. Cell Death Differ. 2016 Nov 11. doi: 10.1038/cdd.2016.118. [Epub ahead of print].

Metformin decreases progerin expression and alleviates pathological defects of Hutchinson-Gilford progeria syndrome cells

Authors:
Egesipe A-L, Blondel S, Cicero AL, Jaskowiak A-L, Navarro C, De Sandre-Giovannoli A, Levy N, Peschanski M, Nissan X.
Citation:
npj Aging and Mechanisms of Disease. 2016;2:16026. doi:10.1038/npjamd.2016.26
Epub:
Not Epub
Abstract:
Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder that causes systemic accelerated aging in children. This...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: MSCs derived from HGPS iPS cells
Citation Extract:
Egesipe A-L, Blondel S, Cicero AL, Jaskowiak A-L, Navarro C, De Sandre-Giovannoli A, Levy N, Peschanski M, Nissan X.. Metformin decreases progerin expression and alleviates pathological defects of Hutchinson-Gilford progeria syndrome cells. npj Aging and Mechanisms of Disease. 2016;2:16026. doi:10.1038/npjamd.2016.26.

Human c-MYBPC3 RNA Targeted Therapy, Reversal of Hypertrophic Cardiomyopathy in the Zebrafish Model

Authors:
Yalcin H, Da’as SI, Mohammed IA, Nasrallah GK, Al Suwaidi J, Yacoub MH
Citation:
Qatar Foundation Annual Research Conference Proceedings 2016;HBPP2955 http://dx.doi.org/10.5339/qfarc.2016.HBPP2955
Epub:
Not Epub
Abstract:
Hypertrophic cardiomyopathy (HCM) is a serious heart disease and is defined as abnormal left ventricular (LV) wall thickening...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yalcin H, Da’as SI, Mohammed IA, Nasrallah GK, Al Suwaidi J, Yacoub MH. Human c-MYBPC3 RNA Targeted Therapy, Reversal of Hypertrophic Cardiomyopathy in the Zebrafish Model. Qatar Foundation Annual Research Conference Proceedings 2016;HBPP2955 http://dx.doi.org/10.5339/qfarc.2016.HBPP2955.

The tbx2a/b transcription factors direct pronephros segmentation and corpuscle of Stannius formation in zebrafish

Authors:
Drummond BE, Li Y, Marra AN, Cheng CN, Wingert RA
Citation:
Dev Biol. 2016 Nov 10. pii: S0012-1606(16)30334-7. doi: 10.1016/j.ydbio.2016.10.019. [Epub ahead of print]
Epub:
Yes
Abstract:
The simplified and genetically conserved zebrafish pronephros is an excellent model to examine the cryptic processes of cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Drummond BE, Li Y, Marra AN, Cheng CN, Wingert RA. The tbx2a/b transcription factors direct pronephros segmentation and corpuscle of Stannius formation in zebrafish. Dev Biol. 2016 Nov 10. pii: S0012-1606(16)30334-7. doi: 10.1016/j.ydbio.2016.10.019. [Epub ahead of print].

Zebrafish Model for Functional Screening of Flow-Responsive Genes

Authors:
Serbanovic-Canic J, de Luca A, Warboys C, Ferreira PF, Luong LA, Hsiao S, Gauci I, Mahmoud M, Feng S, Souilhol C, Bowden N, Ashton JP, Walczak H, Firmin D, Krams R, Mason JC, Haskard DO, Sherwin S, Ridger V, Chico TJ, Evans PC
Citation:
Arterioscler Thromb Vasc Biol. 2016 Nov 10. pii: ATVBAHA.116.308502. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVE: Atherosclerosis is initiated at branches and bends of arteries exposed to disturbed blood flow that generates low...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Serbanovic-Canic J, de Luca A, Warboys C, Ferreira PF, Luong LA, Hsiao S, Gauci I, Mahmoud M, Feng S, Souilhol C, Bowden N, Ashton JP, Walczak H, Firmin D, Krams R, Mason JC, Haskard DO, Sherwin S, Ridger V, Chico TJ, Evans PC. Zebrafish Model for Functional Screening of Flow-Responsive Genes. Arterioscler Thromb Vasc Biol. 2016 Nov 10. pii: ATVBAHA.116.308502. [Epub ahead of print].

NgAgo-based fabp11a gene knockdown causes eye developmental defects in zebrafish

Authors:
Qi J, Dong Z, Shi Y, Wang X, Qin Y, Wang Y, Liu D
Citation:
Cell Res. 2016 Nov 11. doi: 10.1038/cr.2016.134. [Epub ahead of print] No abstract available
Epub:
Not Epub
Abstract:
A recent report of genome editing using Natronobacterium gregoryi Argonaute (NgAgo) with guide DNA (gDNA) in human cells...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Qi J, Dong Z, Shi Y, Wang X, Qin Y, Wang Y, Liu D. NgAgo-based fabp11a gene knockdown causes eye developmental defects in zebrafish. Cell Res. 2016 Nov 11. doi: 10.1038/cr.2016.134. [Epub ahead of print] No abstract available.

Identification of medaka magnetoreceptor and cryptochromes

Authors:
Wang Y, Chen J, Zhu F, Hong Y
Citation:
Sci China Life Sci. 2016 Nov 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Magnetoreception is a hallmark ability of animals for orientation and migration via sensing and utilizing geomagnetic fields....
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Wang Y, Chen J, Zhu F, Hong Y. Identification of medaka magnetoreceptor and cryptochromes. Sci China Life Sci. 2016 Nov 17. [Epub ahead of print].

Somite-Derived Retinoic Acid Regulates Zebrafish Hematopoietic Stem Cell Formation

Authors:
Pillay LM, Mackowetzky KJ, Widen SA, Waskiewicz AJ
Citation:
PLoS One. 2016 Nov 18;11(11):e0166040. doi: 10.1371/journal.pone.0166040
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) are multipotent progenitors that generate all vertebrate adult blood lineages. Recent analyses...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pillay LM, Mackowetzky KJ, Widen SA, Waskiewicz AJ. Somite-Derived Retinoic Acid Regulates Zebrafish Hematopoietic Stem Cell Formation. PLoS One. 2016 Nov 18;11(11):e0166040. doi: 10.1371/journal.pone.0166040.

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