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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Mutations in MYT1, encoding the myelin transcription factor 1, are a rare cause of OAVS

Authors:
Lopez E, Berenguer M, Tingaud-Sequeira A, Marlin S, Toutain A, Denoyelle F, Picard A, Charron S, Mathieu G, de Belvalet H, Arveiler B, Babin PJ, Lacombe D, Rooryck C
Citation:
J Med Genet. 2016;[Epub ahead of print] doi:10.1136/jmedgenet-2016-103774
Epub:
Not Epub
Abstract:
Background: Oculo-auriculo-vertebral spectrum (OAVS) is a developmental disorder involving first and second branchial arches...
Organism or Cell Type:
zebrafish
Citation Extract:
Lopez E, Berenguer M, Tingaud-Sequeira A, Marlin S, Toutain A, Denoyelle F, Picard A, Charron S, Mathieu G, de Belvalet H, Arveiler B, Babin PJ, Lacombe D, Rooryck C . Mutations in MYT1, encoding the myelin transcription factor 1, are a rare cause of OAVS. J Med Genet. 2016;[Epub ahead of print] doi:10.1136/jmedgenet-2016-103774.

TNFα Impairs Rhabdoviral Clearance by Inhibiting the Host Autophagic Antiviral Response

Authors:
Espín-Palazón R, Martínez-López A, Roca FJ, López-Muñoz A, Tyrkalska SD, Candel S, García-Moreno D, Falco A, Meseguer J, Estepa A, Mulero V
Citation:
PLoS Pathog. 2016;12(6):e1005699. doi:10.1371/journal.ppat.1005699
Epub:
Not Epub
Abstract:
TNFα is a pleiotropic pro-inflammatory cytokine with a key role in the activation of the immune system to fight viral...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Espín-Palazón R, Martínez-López A, Roca FJ, López-Muñoz A, Tyrkalska SD, Candel S, García-Moreno D, Falco A, Meseguer J, Estepa A, Mulero V. TNFα Impairs Rhabdoviral Clearance by Inhibiting the Host Autophagic Antiviral Response. PLoS Pathog. 2016;12(6):e1005699. doi:10.1371/journal.ppat.1005699.

Memory of cell shape biases stochastic fate decision-making despite mitotic rounding

Authors:
Akanuma T, Chen C, Sato T, Merks RMH, Sato TN
Citation:
Nat Comm. 2016;7:11963. doi:10.1038/ncomms11963
Epub:
Not Epub
Abstract:
Cell shape influences function, and the current model suggests that such shape effect is transient. However, cells dynamically...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Akanuma T, Chen C, Sato T, Merks RMH, Sato TN. Memory of cell shape biases stochastic fate decision-making despite mitotic rounding. Nat Comm. 2016;7:11963. doi:10.1038/ncomms11963.

Reprogramming of avian neural crest axial identity and cell fate

Authors:
Simoes-Costa M, Bronner ME
Citation:
Science. 2016 Jun 24;352(6293):1570-3. doi: 10.1126/science.aaf2729
Epub:
Not Epub
Abstract:
Neural crest populations along the embryonic body axis of vertebrates differ in developmental potential and fate, so that only...
Delivery Method:
injection then electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Simoes-Costa M, Bronner ME. Reprogramming of avian neural crest axial identity and cell fate. Science. 2016 Jun 24;352(6293):1570-3. doi: 10.1126/science.aaf2729.

N-cadherin relocalization during cardiac trabeculation

Authors:
Cherian AV, Fukuda R, Augustine SM, Maischein HM, Stainier DY
Citation:
Proc Natl Acad Sci U S A. 2016 Jun 23. pii: 201606385. [Epub ahead of print]
Epub:
Yes
Abstract:
During cardiac trabeculation, cardiomyocytes delaminate from the outermost (compact) layer to form complex muscular structures...
Organism or Cell Type:
zebrafish
Citation Extract:
Cherian AV, Fukuda R, Augustine SM, Maischein HM, Stainier DY. N-cadherin relocalization during cardiac trabeculation. Proc Natl Acad Sci U S A. 2016 Jun 23. pii: 201606385. [Epub ahead of print].

Secreted frizzled-related protein 2 (sFRP2) redirects non-canonical Wnt signaling from Fz7 to Ror2 during vertebrate gastrulation

Authors:
Brinkmann EM, Mattes B, Kumar R, Hagemann AI, Gradl D, Scholpp S, Steinbeisser H, Kaufmann LT, Ozbek S
Citation:
J Biol Chem. 2016 Apr 29. pii: jbc.M116.733766. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Convergent extension (CE) movements during vertebrate gastrulation require a balanced activity of non-canonical Wnt signaling...
Citation Extract:
Brinkmann EM, Mattes B, Kumar R, Hagemann AI, Gradl D, Scholpp S, Steinbeisser H, Kaufmann LT, Ozbek S. Secreted frizzled-related protein 2 (sFRP2) redirects non-canonical Wnt signaling from Fz7 to Ror2 during vertebrate gastrulation. J Biol Chem. 2016 Apr 29. pii: jbc.M116.733766. [Epub ahead of print].

A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification

Authors:
Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM
Citation:
Cell Rep. 2016 Jun 15. pii: S2211-1247(16)30658-1. doi: 10.1016/j.celrep.2016.05.060. [Epub ahead of print]
Epub:
Yes
Abstract:
Organogenesis of the trachea and lungs requires a complex series of mesoderm-endoderm interactions mediated by WNT, BMP,...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM, Shannon JM, Zorn AM . A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification. Cell Rep. 2016 Jun 15. pii: S2211-1247(16)30658-1. doi: 10.1016/j.celrep.2016.05.060. [Epub ahead of print].

Rx3 and Shh direct anisotropic growth and specification in the zebrafish tuberal/anterior hypothalamus

Authors:
Muthu V, Eachus H, Ellis P, Brown S, Placzek M
Citation:
Development. 2016 Jun 17. pii: dev.138305. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In the developing brain, growth and differentiation are intimately linked. Here we show that in the zebrafish embryo, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Muthu V, Eachus H, Ellis P, Brown S, Placzek M. Rx3 and Shh direct anisotropic growth and specification in the zebrafish tuberal/anterior hypothalamus. Development. 2016 Jun 17. pii: dev.138305. [Epub ahead of print].

Two novel EIF2S3 mutations associated with syndromic intellectual disability with severe microcephaly, growth retardation, and epilepsy

Authors:
Moortgat S, Désir J, Benoit V, Boulanger S, Pendeville H, Nassogne MC, Lederer D, Maystadt I
Citation:
Am J Med Genet A. 2016 Jun 22. doi: 10.1002/ajmg.a.37792. [Epub ahead of print]
Epub:
Not Epub
Abstract:
X-chromosome exome sequencing was performed to identify the genetic cause of syndromic intellectual disability in two unrelated...
Organism or Cell Type:
zebrafish
Citation Extract:
Moortgat S, Désir J, Benoit V, Boulanger S, Pendeville H, Nassogne MC, Lederer D, Maystadt I. Two novel EIF2S3 mutations associated with syndromic intellectual disability with severe microcephaly, growth retardation, and epilepsy. Am J Med Genet A. 2016 Jun 22. doi: 10.1002/ajmg.a.37792. [Epub ahead of print].

Dazl is a critical player for primordial germ cell formation in medaka

Authors:
Li M, Zhu F, Li Z, Hong N, Hong Y
Citation:
Sci Rep. 2016 Jun 22;6:28317. doi: 10.1038/srep28317
Epub:
Not Epub
Abstract:
The DAZ family genes boule, daz and dazl have conserved functions in primordial germ cell (PGC) migration, germ stem cell...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Li M, Zhu F, Li Z, Hong N, Hong Y. Dazl is a critical player for primordial germ cell formation in medaka. Sci Rep. 2016 Jun 22;6:28317. doi: 10.1038/srep28317.

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