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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
The role of RhoA in retrograde neuronal death and axon regeneration after spinal cord injury
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Citation:
Neurobiol Dis. 2016 Nov 22. pii: S0969-9961(16)30264-9. doi: 10.1016/j.nbd.2016.11.006. [Epub ahead of print] Epub:
Yes Abstract:
Paralysis following spinal cord injury (SCI) is due to interruption of axons and their failure to regenerate. It has been... Delivery Method:
injection Organism or Cell Type:
sea lamprey Citation Extract: Hu J, Zhang G, Rodemer W, Jin LQ, Shifman M, Selzer ME. The role of RhoA in retrograde neuronal death and axon regeneration after spinal cord injury. Neurobiol Dis. 2016 Nov 22. pii: S0969-9961(16)30264-9. doi: 10.1016/j.nbd.2016.11.006. [Epub ahead of print]. |
Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2'-O-Methyl Mixmer Antisense Oligonucleotide
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Citation:
Molecules. 2016 Nov 22;21(11). pii: E1582 Epub:
Not Epub Abstract:
In this study, we synthesised a morpholino nucleoside-uridine (MNA-U) phosphoramidite and evaluated the potential of a MNA-... Delivery Method:
Lipofectin Organism or Cell Type:
cultured cells: Immortalised mdx myoblasts (H2K cells) Citation Extract: Chen S, Le BT, Rahimizadeh K, Shaikh K, Mohal N, Veedu RN. Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2'-O-Methyl Mixmer Antisense Oligonucleotide. Molecules. 2016 Nov 22;21(11). pii: E1582. |
MicroRNAs regulate gene plasticity during cold shock in zebrafish larvae
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Citation:
BMC Genomics. 2016 Nov 15;17(1):922 Epub:
Not Epub Abstract:
BACKGROUND: MicroRNAs (miRNAs) are critical regulators responding to acute environmental stresses in both plants and animals.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hung IC, Hsiao YC, Sun HS, Chen TM, Lee SJ. MicroRNAs regulate gene plasticity during cold shock in zebrafish larvae. BMC Genomics. 2016 Nov 15;17(1):922. |
The sensitivity of the DNA damage checkpoint prevents oocyte maturation in endometriosis
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Citation:
Sci Rep. 2016 Nov 14;6:36994. doi: 10.1038/srep36994 Epub:
Not Epub Abstract:
Mouse oocytes respond to DNA damage by arresting in meiosis I through activity of the Spindle Assembly Checkpoint (SAC) and DNA... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Hamdan M, Jones KT, Cheong Y, Lane SI. The sensitivity of the DNA damage checkpoint prevents oocyte maturation in endometriosis. Sci Rep. 2016 Nov 14;6:36994. doi: 10.1038/srep36994. |
Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry
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Citation:
J Am Chem Soc. 2016;[Epub ahead of print] doi:10.1021/jacs.6b08854 Epub:
Yes Abstract:
Phosphorodiamidate morpholinos (PMOs) and PMO-DNA chimeras have been prepared on DNA synthesizers using phosphoramidite... Citation Extract: Paul S, Caruthers MH. Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry. J Am Chem Soc. 2016;[Epub ahead of print] doi:10.1021/jacs.6b08854. |
In vivo knockdown of FGFR2 and MET mRNA in trophectoderm of ovine conceptuses retards their development via abrogation of MAPK and MTOR pathways
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Citation:
J Animal Sci. 2016;94(supp 5):376 Epub:
Not Epub Abstract:
Wang X, Dunlap KA, Satterfield MC, Wu G, Bazer FW. In vivo knockdown of FGFR2 and MET mRNA in trophectoderm of ovine... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Ovis aries (sheep) conceptus Citation Extract: Wang X, Dunlap KA, Satterfield MC, Wu G, Bazer FW. In vivo knockdown of FGFR2 and MET mRNA in trophectoderm of ovine conceptuses retards their development via abrogation of MAPK and MTOR pathways. J Animal Sci. 2016;94(supp 5):376. |
Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy
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Citation:
Cell Death Differ. 2016 Nov 11. doi: 10.1038/cdd.2016.127. [Epub ahead of print] Epub:
Yes Abstract:
Dystrophin deficiency is the genetic basis for Duchenne muscular dystrophy (DMD), but the cellular basis of progressive... Delivery Method:
injection Organism or Cell Type:
mice, mdx Citation Extract: Vila MC, Rayavarapu S, Hogarth MW, Van der Meulen JH, Horn A, Defour A, Takeda S, Brown KJ, Hathout Y, Nagaraju K, Jaiswal JK. Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy. Cell Death Differ. 2016 Nov 11. doi: 10.1038/cdd.2016.127. [Epub ahead of print]. |
CFTR-β-catenin interaction regulates mouse embryonic stem cell differentiation and embryonic development
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Citation:
Cell Death Differ. 2016 Nov 11. doi: 10.1038/cdd.2016.118. [Epub ahead of print] Epub:
Yes Abstract:
Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-regulated anion channel capable of conducting both Cl- and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Liu Z, Guo J, Wang Y, Weng Z, Huang B, Yu MK, Zhang X, Yuan P, Zhao H, Chan WY, Jiang X, Chan HC. CFTR-β-catenin interaction regulates mouse embryonic stem cell differentiation and embryonic development. Cell Death Differ. 2016 Nov 11. doi: 10.1038/cdd.2016.118. [Epub ahead of print]. |
Metformin decreases progerin expression and alleviates pathological defects of Hutchinson-Gilford progeria syndrome cells
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Citation:
npj Aging and Mechanisms of Disease. 2016;2:16026. doi:10.1038/npjamd.2016.26 Epub:
Not Epub Abstract:
Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder that causes systemic accelerated aging in children. This... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: MSCs derived from HGPS iPS cells Citation Extract: Egesipe A-L, Blondel S, Cicero AL, Jaskowiak A-L, Navarro C, De Sandre-Giovannoli A, Levy N, Peschanski M, Nissan X.. Metformin decreases progerin expression and alleviates pathological defects of Hutchinson-Gilford progeria syndrome cells. npj Aging and Mechanisms of Disease. 2016;2:16026. doi:10.1038/npjamd.2016.26. |
Human c-MYBPC3 RNA Targeted Therapy, Reversal of Hypertrophic Cardiomyopathy in the Zebrafish Model
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Citation:
Qatar Foundation Annual Research Conference Proceedings 2016;HBPP2955 http://dx.doi.org/10.5339/qfarc.2016.HBPP2955 Epub:
Not Epub Abstract:
Hypertrophic cardiomyopathy (HCM) is a serious heart disease and is defined as abnormal left ventricular (LV) wall thickening... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yalcin H, Da’as SI, Mohammed IA, Nasrallah GK, Al Suwaidi J, Yacoub MH. Human c-MYBPC3 RNA Targeted Therapy, Reversal of Hypertrophic Cardiomyopathy in the Zebrafish Model. Qatar Foundation Annual Research Conference Proceedings 2016;HBPP2955 http://dx.doi.org/10.5339/qfarc.2016.HBPP2955. |