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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

AMPA glutamate receptors are required for sensory-organ formation and morphogenesis in the basal chordate

Authors:
Hirai S, Hotta K, Kubo Y, Nishino A, Okabe S, Okamura Y, Okado H
Citation:
Proc Natl Acad Sci U S A. 2017;[Epub ahead of print] doi:10.1073/pnas.1612943114
Epub:
Yes
Abstract:
AMPA-type glutamate receptors (GluAs) mediate fast excitatory transmission in the vertebrate central nervous system (CNS), and...
Link:
http://www.pnas.org/content/early/2017/03/21/1612943114.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (ascidian)
Citation Extract:
Hirai S, Hotta K, Kubo Y, Nishino A, Okabe S, Okamura Y, Okado H. AMPA glutamate receptors are required for sensory-organ formation and morphogenesis in the basal chordate. Proc Natl Acad Sci U S A. 2017;[Epub ahead of print] doi:10.1073/pnas.1612943114.

Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance

Authors:
Nakajima H, Yamamoto K, Agarwala S, Terai K, Fukui H, Fukuhara S, Ando K, Miyazaki T, Yokota Y, Schmelzer E, Belting H-G, Affolter M, Lecaudey V, Mochizuki N
Citation:
Dev Cell. 2017;40:523-36. doi:10.1016/j.devcel.2017.02.019
Epub:
Not Epub
Abstract:
Endothelial cells (ECs) line the inside of blood vessels and respond to mechanical cues generated by blood flow. Mechanical...
Link:
http://www.cell.com/developmental-cell/fulltext/S1534-5807(17)30115-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nakajima H, Yamamoto K, Agarwala S, Terai K, Fukui H, Fukuhara S, Ando K, Miyazaki T, Yokota Y, Schmelzer E, Belting H-G, Affolter M, Lecaudey V, Mochizuki N. Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance. Dev Cell. 2017;40:523-36. doi:10.1016/j.devcel.2017.02.019.

MicroRNAs Establish Uniform Traits during the Architecture of Vertebrate Embryos

Authors:
Kasper DM, Moro A, Ristori E, Narayanan A, Hill-Teran G, Fleming E, Moreno-Mateos M, Vejnar CE, Zhang J, Lee D, Gu M, Gerstein M, Giraldez A, Nicoli S
Citation:
Dev Cell. 2017;40(6):552-565.e5. doi:10.1016/j.devcel.2017.02.021
Epub:
Not Epub
Abstract:
Proper functioning of an organism requires cells and tissues to behave in uniform, well-organized ways. How this optimum of...
Link:
http://www.cell.com/developmental-cell/pdf/S1534-5807(17)30117-X.pdf
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kasper DM, Moro A, Ristori E, Narayanan A, Hill-Teran G, Fleming E, Moreno-Mateos M, Vejnar CE, Zhang J, Lee D, Gu M, Gerstein M, Giraldez A, Nicoli S. MicroRNAs Establish Uniform Traits during the Architecture of Vertebrate Embryos. Dev Cell. 2017;40(6):552-565.e5. doi:10.1016/j.devcel.2017.02.021.

Fatty acid binding protein 11a is required for brain vessel integrity in zebrafish

Authors:
Zhang J, Qi J, Wu S, Peng L, Shi Y, Yang J, Yin Z, Gao Y, Wang C, Gong J, Zhang H, Zhang J, Liu D
Citation:
Front Physiol. 2017 Apr 11;8:214. doi: 10.3389/fphys.2017.00214. eCollection 2017.
Epub:
Not Epub
Abstract:
The monolayer of endothelial cells lining the intima of all blood vessel wall forms a semipermeable barrier that regulates...
Link:
http://journal.frontiersin.org/article/10.3389/fphys.2017.00214/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang J, Qi J, Wu S, Peng L, Shi Y, Yang J, Yin Z, Gao Y, Wang C, Gong J, Zhang H, Zhang J, Liu D. Fatty acid binding protein 11a is required for brain vessel integrity in zebrafish. Front Physiol. 2017 Apr 11;8:214. doi: 10.3389/fphys.2017.00214. eCollection 2017..

Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis

Authors:
Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MDJ, Zhang K, Merkurjev D, De Robertis EM
Citation:
Proc Natl Acad Sci U S A. 2017;[Epub ahead of print] doi:10.1073/pnas.1700766114
Epub:
Yes
Abstract:
The earliest event in Xenopus development is the dorsal accumulation of nuclear β-catenin under the influence of cytoplasmic...
Link:
http://www.pnas.org/content/early/2017/03/22/1700766114.abstract
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MDJ, Zhang K, Merkurjev D, De Robertis EM. Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis. Proc Natl Acad Sci U S A. 2017;[Epub ahead of print] doi:10.1073/pnas.1700766114.

Cos2/Kif7 and OSM-3/Kif17 Regulate Onset of Outer Segment Development in Zebrafish Photoreceptors Through Distinct Mechanisms

Authors:
Lewis TR, Kundinger SR, Pavlovich AL, Bostrom JR, Link BA, Besharse JC
Citation:
Dev Biol. 2017 Mar 21. pii: S0012-1606(17)30126-4. doi: 10.1016/j.ydbio.2017.03.019. [Epub ahead of print]
Epub:
Yes
Abstract:
Zebrafish morphants of osm-3/kif17, a kinesin-2 family member and intraflagellar transport motor, have photoreceptor outer...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160617301264
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lewis TR, Kundinger SR, Pavlovich AL, Bostrom JR, Link BA, Besharse JC. Cos2/Kif7 and OSM-3/Kif17 Regulate Onset of Outer Segment Development in Zebrafish Photoreceptors Through Distinct Mechanisms. Dev Biol. 2017 Mar 21. pii: S0012-1606(17)30126-4. doi: 10.1016/j.ydbio.2017.03.019. [Epub ahead of print].

La-related protein 6 controls ciliated cell differentiation

Authors:
Manojlovic Z, Earwood R, Kato A, Perez D, Cabrera OA, Didier R, Megraw TL, Stefanovic B, Kato Y
Citation:
Cilia. 2017 Mar 23;6:4. doi: 10.1186/s13630-017-0047-7. eCollection 2017 Mar 23
Epub:
Not Epub
Abstract:
BACKGROUND: La-related protein 6 (LARP6) is an evolutionally conserved RNA-binding protein. Vertebrate LARP6 binds the 5'...
Link:
https://ciliajournal.biomedcentral.com/articles/10.1186/s13630-017-0047-7
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Manojlovic Z, Earwood R, Kato A, Perez D, Cabrera OA, Didier R, Megraw TL, Stefanovic B, Kato Y. La-related protein 6 controls ciliated cell differentiation. Cilia. 2017 Mar 23;6:4. doi: 10.1186/s13630-017-0047-7. eCollection 2017 Mar 23.

The chemokine receptor CXCR4 promotes granuloma formation by sustaining a mycobacteria-induced angiogenesis programme

Authors:
Torraca V, Tulotta C, Snaar-Jagalska BE, Meijer AH
Citation:
Sci Rep. 2017 Mar 23;7:45061. doi: 10.1038/srep45061
Epub:
Not Epub
Abstract:
CXC chemokine receptor 4 plays a critical role in chemotaxis and leukocyte differentiation. Furthermore, there is increasing...
Link:
http://www.nature.com/articles/srep45061
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Torraca V, Tulotta C, Snaar-Jagalska BE, Meijer AH. The chemokine receptor CXCR4 promotes granuloma formation by sustaining a mycobacteria-induced angiogenesis programme. Sci Rep. 2017 Mar 23;7:45061. doi: 10.1038/srep45061.

Chordin and dickkopf-1b are essential for the formation of head structures through activation of the FGF signaling pathway in zebrafish

Authors:
Tanaka S, Hosokawa H, Weinberg ES, Maegawa S
Citation:
Dev Biol. 2017 Mar 1. pii: S0012-1606(16)30469-9. doi: 10.1016/j.ydbio.2017.02.018. [Epub ahead of print]
Epub:
Yes
Abstract:
The ability of the Spemann organizer to induce dorsal axis formation is dependent on downstream factors of the maternal Wnt/β-...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616304699
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tanaka S, Hosokawa H, Weinberg ES, Maegawa S. Chordin and dickkopf-1b are essential for the formation of head structures through activation of the FGF signaling pathway in zebrafish. Dev Biol. 2017 Mar 1. pii: S0012-1606(16)30469-9. doi: 10.1016/j.ydbio.2017.02.018. [Epub ahead of print].

Inhibition of serum and glucocorticoid regulated kinase-1 as novel therapy for cardiac arrhythmia disorders

Authors:
Bezzerides VJ, Zhang A, Xiao L, Simonson B, Khedkar SA, Baba S, Ottaviano F, Lynch S, Hessler K, Rigby AC, Milan D, Das S, Rosenzweig A
Citation:
Sci Rep. 2017;7:346. doi:10.1038/s41598-017-00413-3
Epub:
Not Epub
Abstract:
Alterations in sodium flux (INa) play an important role in the pathogenesis of cardiac arrhythmias and may also contribute to...
Link:
http://www.nature.com/articles/s41598-017-00413-3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bezzerides VJ, Zhang A, Xiao L, Simonson B, Khedkar SA, Baba S, Ottaviano F, Lynch S, Hessler K, Rigby AC, Milan D, Das S, Rosenzweig A. Inhibition of serum and glucocorticoid regulated kinase-1 as novel therapy for cardiac arrhythmia disorders. Sci Rep. 2017;7:346. doi:10.1038/s41598-017-00413-3.

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