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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis

Authors:
Mueller AA, van Velthoven CT, Fukumoto KD, Cheung TH, Rando TA
Citation:
Nature. 2016 Nov 28. doi: 10.1038/nature20160. [Epub ahead of print]
Epub:
Yes
Abstract:
Platelet-derived growth factor receptor α (PDGFRα) exhibits divergent effects in skeletal muscle. At physiological levels,...
Link:
https://www.nature.com/articles/nature20160
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Mueller AA, van Velthoven CT, Fukumoto KD, Cheung TH, Rando TA. Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis. Nature. 2016 Nov 28. doi: 10.1038/nature20160. [Epub ahead of print].

Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle

Authors:
Taglietti V, Maroli G, Cermenati S, Monteverde S, Ferrante A, Rossi G, Cossu G, Beltrame M, Messina G
Citation:
Cell Rep. 2016 Nov 22;17(9):2354-2366. doi: 10.1016/j.celrep.2016.10.082
Epub:
Not Epub
Abstract:
Sox6 belongs to the Sox gene family and plays a pivotal role in fiber type differentiation, suppressing transcription of slow-...
Link:
http://www.cell.com/cell-reports/abstract/S2211-1247(16)31517-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Taglietti V, Maroli G, Cermenati S, Monteverde S, Ferrante A, Rossi G, Cossu G, Beltrame M, Messina G. Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle. Cell Rep. 2016 Nov 22;17(9):2354-2366. doi: 10.1016/j.celrep.2016.10.082.

Injections of Predatory Bacteria Work Alongside Host Immune Cells to Treat Shigella Infection in Zebrafish Larvae

Authors:
Willis AR, Moore C, Mazon-Moya M, Krokowski S, Lambert C, Till R, Mostowy S, Sockett RE
Citation:
Curr Biol. 2016 Nov 22. pii: S0960-9822(16)31152-6. doi: 10.1016/j.cub.2016.09.067. [Epub ahead of print]
Epub:
Yes
Abstract:
Bdellovibrio bacteriovorus are predatory bacteria that invade and kill a range of Gram-negative bacterial pathogens in natural...
Link:
http://www.cell.com/current-biology/fulltext/S0960-9822(16)31152-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Willis AR, Moore C, Mazon-Moya M, Krokowski S, Lambert C, Till R, Mostowy S, Sockett RE. Injections of Predatory Bacteria Work Alongside Host Immune Cells to Treat Shigella Infection in Zebrafish Larvae. Curr Biol. 2016 Nov 22. pii: S0960-9822(16)31152-6. doi: 10.1016/j.cub.2016.09.067. [Epub ahead of print].

PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis

Authors:
Mana G, Clapero F, Panieri E, Panero V, Böttcher RT, Tseng HY, Saltarin F, Astanina E, Wolanska KI, Morgan MR, Humphries MJ, Santoro MM, Serini G, Valdembri D
Citation:
Nat Commun. 2016 Nov 23;7:13546. doi: 10.1038/ncomms13546
Epub:
Not Epub
Abstract:
Basolateral polymerization of cellular fibronectin (FN) into a meshwork drives endothelial cell (EC) polarity and vascular...
Link:
http://www.nature.com/articles/ncomms13546
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mana G, Clapero F, Panieri E, Panero V, Böttcher RT, Tseng HY, Saltarin F, Astanina E, Wolanska KI, Morgan MR, Humphries MJ, Santoro MM, Serini G, Valdembri D. PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis. Nat Commun. 2016 Nov 23;7:13546. doi: 10.1038/ncomms13546.

Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis

Authors:
Kim W, Khan SK, Gvozdenovic-Jeremic J, Kim Y, Dahlman J, Kim H, Park O, Ishitani T, Jho EH, Gao B, Yang Y
Citation:
J Clin Invest. 2016 Nov 21. pii: 88486. doi: 10.1172/JCI88486. [Epub ahead of print]
Epub:
Yes
Abstract:
Malignant tumors develop through multiple steps of initiation and progression, and tumor initiation is of singular importance...
Link:
https://www.jci.org/articles/view/88486
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim W, Khan SK, Gvozdenovic-Jeremic J, Kim Y, Dahlman J, Kim H, Park O, Ishitani T, Jho EH, Gao B, Yang Y. Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis. J Clin Invest. 2016 Nov 21. pii: 88486. doi: 10.1172/JCI88486. [Epub ahead of print].

Asymmetric division coordinates collective cell migration in angiogenesis

Authors:
Costa G, Harrington KI, Lovegrove HE, Page DJ, Chakravartula S, Bentley K, Herbert SP
Citation:
Nat Cell Biol. 2016 Dec;18(12):1292-1301. doi: 10.1038/ncb3443
Epub:
Not Epub
Abstract:
The asymmetric division of stem or progenitor cells generates daughters with distinct fates and regulates cell diversity during...
Link:
http://www.nature.com/ncb/journal/v18/n12/full/ncb3443.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Costa G, Harrington KI, Lovegrove HE, Page DJ, Chakravartula S, Bentley K, Herbert SP. Asymmetric division coordinates collective cell migration in angiogenesis. Nat Cell Biol. 2016 Dec;18(12):1292-1301. doi: 10.1038/ncb3443.

Identification and angiogenic role of the novel tumor endothelial marker CLEC14A

Authors:
Mura M, Swain RK, Zhuang X, Vorschmitt H, Reynolds G, Durant S, Beesley JF, Herbert JM, Sheldon H, Andre M, Sanderson S, Glen K, Luu NT, McGettrick HM, Antczak P, Falciani F, Nash GB, Nagy ZS, Bicknell R
Citation:
Oncogene. 2012 Jan 19;31(3):293-305. doi: 10.1038/onc.2011.233
Epub:
Not Epub
Abstract:
Tumor endothelial markers (TEMs) that are highly expressed in human tumor vasculature compared with vasculature in normal...
Link:
http://www.nature.com/onc/journal/v31/n3/full/onc2011233a.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mura M, Swain RK, Zhuang X, Vorschmitt H, Reynolds G, Durant S, Beesley JF, Herbert JM, Sheldon H, Andre M, Sanderson S, Glen K, Luu NT, McGettrick HM, Antczak P, Falciani F, Nash GB, Nagy ZS, Bicknell R. Identification and angiogenic role of the novel tumor endothelial marker CLEC14A. Oncogene. 2012 Jan 19;31(3):293-305. doi: 10.1038/onc.2011.233.

Cytochrome P450 26A1 modulates natural killer cells in mouse early pregnancy

Authors:
Meng CY, Li ZY, Fang WN, Song ZH, Yang DD, Li DD, Yang Y, Peng JP
Citation:
J Cell Mol Med. 2016 Nov 17. doi: 10.1111/jcmm.13013. [Epub ahead of print]
Epub:
Yes
Abstract:
Cytochrome P450 26A1 (CYP26A1) has a spatiotemporal expression pattern in the uterus, with a significant increase in mRNA and...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/jcmm.13013/full
Delivery Method:
intrauterine injection
Organism or Cell Type:
mice
Citation Extract:
Meng CY, Li ZY, Fang WN, Song ZH, Yang DD, Li DD, Yang Y, Peng JP. Cytochrome P450 26A1 modulates natural killer cells in mouse early pregnancy. J Cell Mol Med. 2016 Nov 17. doi: 10.1111/jcmm.13013. [Epub ahead of print].

ELMO1 protects renal structure and ultrafiltration in kidney development and under diabetic conditions

Authors:
Sharma KR, Heckler K, Stoll SJ, Hillebrands JL, Kynast K, Herpel E, Porubsky S, Elger M, Hadaschik B, Bieback K, Hammes HP, Nawroth PP, Kroll J
Citation:
Sci Rep. 2016 Nov 16;6:37172. doi: 10.1038/srep37172
Epub:
Not Epub
Abstract:
Engulfment and cell motility 1 (ELMO1) functions as a guanine exchange factor for Rac1 and was recently found to protect...
Link:
http://www.nature.com/articles/srep37172
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sharma KR, Heckler K, Stoll SJ, Hillebrands JL, Kynast K, Herpel E, Porubsky S, Elger M, Hadaschik B, Bieback K, Hammes HP, Nawroth PP, Kroll J. ELMO1 protects renal structure and ultrafiltration in kidney development and under diabetic conditions. Sci Rep. 2016 Nov 16;6:37172. doi: 10.1038/srep37172.

Exon skipping of FcεRIβ eliminates expression of the high-affinity IgE receptor in mast cells with therapeutic potential for allergy

Authors:
Cruse G, Yin Y, Fukuyama T, Desai A, Arthur GK, Bäumer W, Beaven MA, Metcalfe DD
Citation:
Proc Natl Acad Sci U S A. 2016 Nov 21. pii: 201608520. [Epub ahead of print]
Epub:
Yes
Abstract:
Allergic diseases are driven by activation of mast cells and release of mediators in response to IgE-directed antigens. However...
Link:
http://www.pnas.org/content/early/2016/11/16/1608520113.long
Delivery Method:
electroporation for cultures, Vivo-Morpholino for skin treatment
Organism or Cell Type:
cell culture: mouse primary mouse and human bone marrow-derived mast cells (BMMCs), mice
Citation Extract:
Cruse G, Yin Y, Fukuyama T, Desai A, Arthur GK, Bäumer W, Beaven MA, Metcalfe DD. Exon skipping of FcεRIβ eliminates expression of the high-affinity IgE receptor in mast cells with therapeutic potential for allergy. Proc Natl Acad Sci U S A. 2016 Nov 21. pii: 201608520. [Epub ahead of print].

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