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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12165 scientific papers returned from the database with the search filters currently being used below.

The presence of Anf/Hesx1 homeobox gene in lampreys suggests that it could play an important role in emergence of telencephalon

Authors:
Bayramov AV, Ermakova GV, Eroshkin FM, Kucheryavyy AV, Martynova NY, Zaraisky AG
Citation:
Sci Rep. 2016 Dec 23;6:39849. doi: 10.1038/srep39849
Epub:
Not Epub
Abstract:
Accumulated evidence indicates that the core genetic mechanisms regulating early patterning of the brain rudiment in...
Delivery Method:
microinjection
Organism or Cell Type:
Lampetra fluviatilis (lamprey), Xenopus laevis
Citation Extract:
Bayramov AV, Ermakova GV, Eroshkin FM, Kucheryavyy AV, Martynova NY, Zaraisky AG. The presence of Anf/Hesx1 homeobox gene in lampreys suggests that it could play an important role in emergence of telencephalon. Sci Rep. 2016 Dec 23;6:39849. doi: 10.1038/srep39849.

Lens defects in Astyanax mexicanus Cavefish: evolution of crystallins and a role for alphaA-crystallin

Authors:
Hinaux H, Blin M, Fumey J, Legendre L, Heuzé A, Casane D, Rétaux S
Citation:
Dev Neurobiol. 2015 May;75(5):505-21. doi: 10.1002/dneu.22239
Epub:
Not Epub
Abstract:
The fish Astyanax mexicanus presents, within the same species, populations of river-dwelling surface fish (SF) and blind cave-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hinaux H, Blin M, Fumey J, Legendre L, Heuzé A, Casane D, Rétaux S. Lens defects in Astyanax mexicanus Cavefish: evolution of crystallins and a role for alphaA-crystallin. Dev Neurobiol. 2015 May;75(5):505-21. doi: 10.1002/dneu.22239.

Congenital myopathy results from misregulation of a muscle Ca2+ channel by mutant Stac3

Authors:
Linsley JW, Hsu IU, Groom L, Yarotskyy V, Lavorato M, Horstick EJ, Linsley D, Wang W, Franzini-Armstrong C, Dirksen RT, Kuwada JY
Citation:
Proc Natl Acad Sci U S A. 2016 Dec 21. pii: 201619238. doi: 10.1073/pnas.1619238114. [Epub ahead of print]
Epub:
Yes
Abstract:
Skeletal muscle contractions are initiated by an increase in Ca2+ released during excitation-contraction (EC) coupling, and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Linsley JW, Hsu IU, Groom L, Yarotskyy V, Lavorato M, Horstick EJ, Linsley D, Wang W, Franzini-Armstrong C, Dirksen RT, Kuwada JY. Congenital myopathy results from misregulation of a muscle Ca2+ channel by mutant Stac3. Proc Natl Acad Sci U S A. 2016 Dec 21. pii: 201619238. doi: 10.1073/pnas.1619238114. [Epub ahead of print].

The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation

Authors:
Mahale S, Kumar M, Sharma A, Babu A, Ranjan S, Sachidanandan C, Mylavarapu SV
Citation:
Sci Rep. 2016 Dec;6(1):22. doi: 10.1038/s41598-016-0030-3
Epub:
Not Epub
Abstract:
Cytoplasmic dynein 1 is a multi-protein intracellular motor essential for mediating several mitotic functions, including the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mahale S, Kumar M, Sharma A, Babu A, Ranjan S, Sachidanandan C, Mylavarapu SV. The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation. Sci Rep. 2016 Dec;6(1):22. doi: 10.1038/s41598-016-0030-3.

HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels

Authors:
Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A
Citation:
Nat Commun. 2016 Dec 22;7:13889. doi: 10.1038/ncomms13889
Epub:
Not Epub
Abstract:
A fundamental question is how autophagosome formation is regulated. Here we show that the PX domain protein HS1BP3 is a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A. HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels. Nat Commun. 2016 Dec 22;7:13889. doi: 10.1038/ncomms13889.

Transcriptome Profiling Identifies Ribosome Biogenesis as a Target of Alcohol Teratogenicity and Vulnerability during Early Embryogenesis

Authors:
Berres ME, Garic A, Flentke GR, Smith SM
Citation:
PLoS ONE. 2017;12(1):e0169351. doi:10.1371/journal.pone.0169351
Epub:
Not Epub
Abstract:
Fetal alcohol spectrum disorder (FASD) is a leading cause of neurodevelopmental disability. Individuals with FASD may exhibit a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Berres ME, Garic A, Flentke GR, Smith SM. Transcriptome Profiling Identifies Ribosome Biogenesis as a Target of Alcohol Teratogenicity and Vulnerability during Early Embryogenesis. PLoS ONE. 2017;12(1):e0169351. doi:10.1371/journal.pone.0169351.

Transient Inhibition of Endogenous Transforming Growth Factor- β1 (TGFβ1) in Hematopoietic Stem Cells Accelerates Engraftment and Enhances Multi-Lineage Repopulating Efficiency

Authors:
Bartelmez S, Storey C, Iversen P, Ruscetti F
Citation:
J Stem Cell Res Ther. 2016;1(7):00045. doi:10.15406/jsrt.2016.01.00045
Epub:
Not Epub
Abstract:
We show that ex vivo transient inhibition of endogenous transforming growth factor-β1 (TGFβ1) in highly enriched and partially...
Organism or Cell Type:
mouse with ex-vivo-treatment & return: Long Term Repopulating-Hematopoietic Stem Cells
Citation Extract:
Bartelmez S, Storey C, Iversen P, Ruscetti F. Transient Inhibition of Endogenous Transforming Growth Factor- β1 (TGFβ1) in Hematopoietic Stem Cells Accelerates Engraftment and Enhances Multi-Lineage Repopulating Efficiency. J Stem Cell Res Ther. 2016;1(7):00045. doi:10.15406/jsrt.2016.01.00045.

Blood flow directs arterial-venous remodeling through Notch activation and endothelial cell migration

Authors:
Weijts B, Gutierrez E, Saikin SK, Ablooglu AJ, Traver D, Groisman A, Tkachenko E
Citation:
bioRxiv. 2016. doi:10.1101/095307
Epub:
Yes
Abstract:
Arteries and veins are lined by arterial and venous endothelial cells (ECs), which are functionally distinct. During embryonic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weijts B, Gutierrez E, Saikin SK, Ablooglu AJ, Traver D, Groisman A, Tkachenko E. Blood flow directs arterial-venous remodeling through Notch activation and endothelial cell migration. bioRxiv. 2016. doi:10.1101/095307.

RNA activation of haploinsufficient Foxg1 gene in murine neocortex

Authors:
Fimiani C, Goina E, Su Q, Gao G, Mallamaci A
Citation:
Sci Rep. 2016 Dec 20;6:39311. doi: 10.1038/srep39311
Epub:
Not Epub
Abstract:
More than one hundred distinct gene hemizygosities are specifically linked to epilepsy, mental retardation, autism,...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: NIH/3T3
Citation Extract:
Fimiani C, Goina E, Su Q, Gao G, Mallamaci A. RNA activation of haploinsufficient Foxg1 gene in murine neocortex. Sci Rep. 2016 Dec 20;6:39311. doi: 10.1038/srep39311.

Prostaglandin signaling regulates nephron segment patterning of renal progenitors during zebrafish kidney development

Authors:
Poureetezadi SJ, Cheng CN, Chambers JM, Drummond BE, Wingert RA
Citation:
Elife. 2016 Dec 20;5. pii: e17551. doi: 10.7554/eLife.17551
Epub:
Not Epub
Abstract:
Kidney formation involves patterning events that induce renal progenitors to form nephrons with an intricate composition of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Poureetezadi SJ, Cheng CN, Chambers JM, Drummond BE, Wingert RA. Prostaglandin signaling regulates nephron segment patterning of renal progenitors during zebrafish kidney development. Elife. 2016 Dec 20;5. pii: e17551. doi: 10.7554/eLife.17551.

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