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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

THSD1 (Thrombospondin Type 1 Domain Containing Protein 1) Mutation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage

Authors:
Santiago-Sim T, Fang X, Hennessy ML, Nalbach SV, DePalma SR, Lee MS, Greenway SC, McDonough B, Hergenroeder GW, Patek KJ, Colosimo SM, Qualmann KJ, Hagan JP, Milewicz DM, MacRae CA, Dymecki SM, Seidman CE, Seidman JG, Kim DH
Citation:
Stroke. 2016 Dec;47(12):3005-3013
Epub:
Not Epub
Abstract:
Background and Purpose: A ruptured intracranial aneurysm (IA) is the leading cause of a subarachnoid hemorrhage. This study...
Organism or Cell Type:
zebrafish
Citation Extract:
Santiago-Sim T, Fang X, Hennessy ML, Nalbach SV, DePalma SR, Lee MS, Greenway SC, McDonough B, Hergenroeder GW, Patek KJ, Colosimo SM, Qualmann KJ, Hagan JP, Milewicz DM, MacRae CA, Dymecki SM, Seidman CE, Seidman JG, Kim DH. THSD1 (Thrombospondin Type 1 Domain Containing Protein 1) Mutation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage. Stroke. 2016 Dec;47(12):3005-3013.

Role of Androgen Dependent TFPI-Regulating Protein (ADTRP) in Vascular Development and Function

Authors:
Patel MM, Silasi-Mansat R, Keshari RS, Sansam CL, Jones DA, Lupu C, Lupu F
Citation:
Blood. 2016;128(22):556
Epub:
Not Epub
Abstract:
We used in vitro and in vivo models to characterize the physiological role of the novel protein encoded by C6ORF105. This gene...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patel MM, Silasi-Mansat R, Keshari RS, Sansam CL, Jones DA, Lupu C, Lupu F. Role of Androgen Dependent TFPI-Regulating Protein (ADTRP) in Vascular Development and Function. Blood. 2016;128(22):556.

Sterol O-Acyltransferase 2 Contributes to the Yolk Cholesterol Trafficking during Zebrafish Embryogenesis

Authors:
Chang NY, Chan YJ, Ding ST, Lee YH, HuangFu WC, Liu IH
Citation:
PLoS One. 2016 Dec 9;11(12):e0167644. doi: 10.1371/journal.pone.0167644
Epub:
Not Epub
Abstract:
To elucidate whether Sterol O-acyltransferase (Soat) mediates the absorption and transportation of yolk lipids to the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chang NY, Chan YJ, Ding ST, Lee YH, HuangFu WC, Liu IH. Sterol O-Acyltransferase 2 Contributes to the Yolk Cholesterol Trafficking during Zebrafish Embryogenesis. PLoS One. 2016 Dec 9;11(12):e0167644. doi: 10.1371/journal.pone.0167644.

Intron Retention Mechanisms That Regulate SF3B1 and Mitoferrin Gene Expression during Late Erythropoiesis

Authors:
Parra M, Yeo G, Conboy JG
Citation:
Blood. 2016;128:1200
Epub:
Not Epub
Abstract:
Intron retention (IR) regulates hundreds of erythroid genes in a differentiation stage-specific manner during terminal...
Citation Extract:
Parra M, Yeo G, Conboy JG. Intron Retention Mechanisms That Regulate SF3B1 and Mitoferrin Gene Expression during Late Erythropoiesis. Blood. 2016;128:1200.

Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure

Authors:
Abu-Taha IH, Heijman J, Hippe H-J, Wolf NM, El-Armouche A, Nikolaev VO, Schäfer M, Würtz C, Neef S, Voigt N, Baczkó I, Varró A, Müller M, Meder B, Katus HA, Spiger K, Vettel C, Lehmann LH, Backs J, Skolnik EY, Lutz S, Dobrev D,Wieland T
Citation:
Circulation. 2016;[Epub ahead of print] doi:10.1161/CIRCULATIONAHA.116.022852
Epub:
Yes
Abstract:
Background: Chronic heart failure (HF) is associated with altered signal transduction via β-adrenoceptors and G proteins, and...
Citation Extract:
Abu-Taha IH, Heijman J, Hippe H-J, Wolf NM, El-Armouche A, Nikolaev VO, Schäfer M, Würtz C, Neef S, Voigt N, Baczkó I, Varró A, Müller M, Meder B, Katus HA, Spiger K, Vettel C, Lehmann LH, Backs J, Skolnik EY, Lutz S, Dobrev D,Wieland T. Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure. Circulation. 2016;[Epub ahead of print] doi:10.1161/CIRCULATIONAHA.116.022852.

Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development

Authors:
Zhang X, Liu X, Zhang M, Li T, Muth A, Thompson PA, Coonrod SA, Zhang X
Citation:
Sci Rep. 2016:6:38727. doi:10.1038/srep38727
Epub:
Not Epub
Abstract:
Peptidylarginine deiminase (PADI) enzymes are increasingly being associated with the regulation of chromatin structure and gene...
Delivery Method:
microinjection
Organism or Cell Type:
mouse zygotes
Citation Extract:
Zhang X, Liu X, Zhang M, Li T, Muth A, Thompson PA, Coonrod SA, Zhang X. Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development. Sci Rep. 2016:6:38727. doi:10.1038/srep38727.

Glut1/SLC2A1 is crucial for the development of the blood-brain barrier in vivo

Authors:
Zheng PP, Romme E, van der Spek PJ, Dirven CM, Willemsen R, Kros JM
Citation:
Ann Neurol. 2010 Dec;68(6):835-44. doi: 10.1002/ana.22318
Epub:
Not Epub
Abstract:
OBJECTIVE: The overall permeability of the blood-brain barrier (BBB) is regulated by specialized cerebral endothelial cells and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zheng PP, Romme E, van der Spek PJ, Dirven CM, Willemsen R, Kros JM. Glut1/SLC2A1 is crucial for the development of the blood-brain barrier in vivo. Ann Neurol. 2010 Dec;68(6):835-44. doi: 10.1002/ana.22318.

Overexpression of TGF-β Inducible microRNA-143 in Zebrafish Leads to Impairment of the Glomerular Filtration Barrier by Targeting Proteoglycans

Authors:
Müller-Deile J, Gellrich F, Schenk H, Schroder P, Nyström J, Lorenzen J, Haller H, Schiffer M
Citation:
Cell Physiol Biochem. 2016;40(5):819-30. doi:10.1159/000453142
Epub:
Not Epub
Abstract:
Background: TGF-β is known as an important stress factor of podocytes in glomerular diseases. Apart from activation of direct...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Müller-Deile J, Gellrich F, Schenk H, Schroder P, Nyström J, Lorenzen J, Haller H, Schiffer M. Overexpression of TGF-β Inducible microRNA-143 in Zebrafish Leads to Impairment of the Glomerular Filtration Barrier by Targeting Proteoglycans. Cell Physiol Biochem. 2016;40(5):819-30. doi:10.1159/000453142.

In Vivo Visualization of Cardiomyocyte Apicobasal Polarity Reveals Epithelial to Mesenchymal-like Transition during Cardiac Trabeculation

Authors:
Jiménez-Amilburu V, Rasouli SJ, Staudt DW, Nakajima H, Chiba A, Mochizuki N, Stainier DYR
Citation:
Cell Rep. 2016;17:2687-99. doi:10.1016/j.celrep.2016.11.023
Epub:
Not Epub
Abstract:
Despite great strides in understanding cardiac trabeculation, many mechanistic aspects remain unclear. To elucidate how...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jiménez-Amilburu V, Rasouli SJ, Staudt DW, Nakajima H, Chiba A, Mochizuki N, Stainier DYR. In Vivo Visualization of Cardiomyocyte Apicobasal Polarity Reveals Epithelial to Mesenchymal-like Transition during Cardiac Trabeculation. Cell Rep. 2016;17:2687-99. doi:10.1016/j.celrep.2016.11.023.

cMyc Regulates the Size of the Premigratory Neural Crest Stem Cell Pool

Authors:
Kerosuo L, Bronner ME
Citation:
Cell Rep. 2016;17:2648-59. doi:10.1016/j.celrep.2016.11.025
Epub:
Not Epub
Abstract:
The neural crest is a transient embryonic population that originates within the central nervous system (CNS) and then migrates...
Delivery Method:
injection then electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Kerosuo L, Bronner ME. cMyc Regulates the Size of the Premigratory Neural Crest Stem Cell Pool. Cell Rep. 2016;17:2648-59. doi:10.1016/j.celrep.2016.11.025.

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