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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Blood flow directs arterial-venous remodeling through Notch activation and endothelial cell migration

Authors:
Weijts B, Gutierrez E, Saikin SK, Ablooglu AJ, Traver D, Groisman A, Tkachenko E
Citation:
bioRxiv. 2016. doi:10.1101/095307
Epub:
Yes
Abstract:
Arteries and veins are lined by arterial and venous endothelial cells (ECs), which are functionally distinct. During embryonic...
Link:
http://biorxiv.org/content/early/2016/12/19/095307
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weijts B, Gutierrez E, Saikin SK, Ablooglu AJ, Traver D, Groisman A, Tkachenko E. Blood flow directs arterial-venous remodeling through Notch activation and endothelial cell migration. bioRxiv. 2016. doi:10.1101/095307.

RNA activation of haploinsufficient Foxg1 gene in murine neocortex

Authors:
Fimiani C, Goina E, Su Q, Gao G, Mallamaci A
Citation:
Sci Rep. 2016 Dec 20;6:39311. doi: 10.1038/srep39311
Epub:
Not Epub
Abstract:
More than one hundred distinct gene hemizygosities are specifically linked to epilepsy, mental retardation, autism,...
Link:
http://www.nature.com/articles/srep39311
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: NIH/3T3
Citation Extract:
Fimiani C, Goina E, Su Q, Gao G, Mallamaci A. RNA activation of haploinsufficient Foxg1 gene in murine neocortex. Sci Rep. 2016 Dec 20;6:39311. doi: 10.1038/srep39311.

Prostaglandin signaling regulates nephron segment patterning of renal progenitors during zebrafish kidney development

Authors:
Poureetezadi SJ, Cheng CN, Chambers JM, Drummond BE, Wingert RA
Citation:
Elife. 2016 Dec 20;5. pii: e17551. doi: 10.7554/eLife.17551
Epub:
Not Epub
Abstract:
Kidney formation involves patterning events that induce renal progenitors to form nephrons with an intricate composition of...
Link:
https://elifesciences.org/content/5/e17551
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Poureetezadi SJ, Cheng CN, Chambers JM, Drummond BE, Wingert RA. Prostaglandin signaling regulates nephron segment patterning of renal progenitors during zebrafish kidney development. Elife. 2016 Dec 20;5. pii: e17551. doi: 10.7554/eLife.17551.

Visual Experience Dependent Regulation of Neuronal Structure and Function by Histone Deacetylase 1 in Developing Xenopus Tectum in vivo

Authors:
Ruan H, Gao J, Qi X, Tao Y, Guo X, Guo Z, Zheng L, Song Y, Liao Y, Shen W
Citation:
Dev Neurobiol. 2016 Dec 29. doi: 10.1002/dneu.22480. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Histone deacetylase 1 (HDAC1) is thought to play pivotal roles in neurogenesis and neurodegeneration. However, the role of...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dneu.22480/abstract
Organism or Cell Type:
Xenopus
Citation Extract:
Ruan H, Gao J, Qi X, Tao Y, Guo X, Guo Z, Zheng L, Song Y, Liao Y, Shen W. Visual Experience Dependent Regulation of Neuronal Structure and Function by Histone Deacetylase 1 in Developing Xenopus Tectum in vivo. Dev Neurobiol. 2016 Dec 29. doi: 10.1002/dneu.22480. [Epub ahead of print].

Impairment of cargo transportation due to gbf1 mutation disrupts vascular integrity and causes hemorrhage in zebrafish embryos

Authors:
Chen J, Wu X, Yao L, Yan L, Zhang L, Qiu J, Liu X, Jia S, Meng A
Citation:
J Biol Chem. 2016 Dec 21. pii: jbc.M116.767608. doi: 10.1074/jbc.M116.767608. [Epub ahead of print]
Epub:
Yes
Abstract:
ADP-ribosylation factor (ARF) GTPases are activated by guanine nucleotide exchange factors including Golgi Brefeldin A-...
Link:
http://www.jbc.org/content/early/2016/12/21/jbc.M116.767608.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen J, Wu X, Yao L, Yan L, Zhang L, Qiu J, Liu X, Jia S, Meng A. Impairment of cargo transportation due to gbf1 mutation disrupts vascular integrity and causes hemorrhage in zebrafish embryos. J Biol Chem. 2016 Dec 21. pii: jbc.M116.767608. doi: 10.1074/jbc.M116.767608. [Epub ahead of print].

Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish

Authors:
Chiba A, Watanabe-Takano H, Terai K, Fukui H, Miyazaki T, Uemura M, Hashimoto H, Hibi M, Fukuhara S, Mochizuki N
Citation:
Development. 2016 Dec 19. pii: dev.143354. [Epub ahead of print]
Epub:
Yes
Abstract:
The heart is an endocrine organ, because cardiomyocytes (CMs) secrete natriuretic peptide (NP) hormones. Since the discovery of...
Link:
http://dev.biologists.org/content/early/2016/12/17/dev.143354.long
Organism or Cell Type:
zebrafish
Citation Extract:
Chiba A, Watanabe-Takano H, Terai K, Fukui H, Miyazaki T, Uemura M, Hashimoto H, Hibi M, Fukuhara S, Mochizuki N. Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish. Development. 2016 Dec 19. pii: dev.143354. [Epub ahead of print].

Drug-free macromolecular therapeutics: Impact of structure on induction of apoptosis in Raji B cells

Authors:
Zhang L, Fang Y, Yang J, Kopeček J
Citation:
J Control Release. 2016 Dec 23. pii: S0168-3659(16)31273-1. doi: 10.1016/j.jconrel.2016.12.025. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Recently, we developed a new paradigm in macromolecular therapeutics that avoids the use of low molecular weight drugs. The...
Link:
http://www.sciencedirect.com/science/article/pii/S0168365916312731
Organism or Cell Type:
cell culture: Raji B cells
Citation Extract:
Zhang L, Fang Y, Yang J, Kopeček J. Drug-free macromolecular therapeutics: Impact of structure on induction of apoptosis in Raji B cells. J Control Release. 2016 Dec 23. pii: S0168-3659(16)31273-1. doi: 10.1016/j.jconrel.2016.12.025. [Epub ahead of print].

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

Authors:
van Rooij FJ, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang LC, Schmidt H, Yang ML, Chen MH, Hayes J, Johnson AD, Yanek LR, Mueller C, Lange L, Floyd JS, Ghanbari M, Zonderman AB, Jukema JW, Hofman A, van Duijn CM, Desch KC, Saba Y, Ozel AB, Snively BM, Wu JY, Schmidt R, Fornage M, Klein RJ, Fox CS, Matsuda K, Kamatani N, Wild PS, Stott DJ, Ford I, Slagboom PE, Yang J, Chu AY, Lambert AJ, Uitterlinden AG, Franco OH, Hofer E, Ginsburg D, Hu B, Keating B, Schick UM, Brody JA, Li JZ, Chen Z, Zeller T, <authors deleted - database limit> Yang Q, Psaty BM, Boerwinkle E, Becker LC, Mook-Kanamori DO, Wilson JG, Gudnason V, O'Donnell CJ, Dehghan A, Cupples LA, Nalls MA, Morris AP, Okada Y, Reiner AP, Zon LI, Ganesh SK
Citation:
Am J Hum Genet. 2016 Dec 19. pii: S0002-9297(16)30520-1. doi: 10.1016/j.ajhg.2016.11.016. [Epub ahead of print]
Epub:
Yes
Abstract:
Genome-wide association studies (GWASs) have identified loci for erythrocyte traits in primarily European ancestry populations...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297(16)30520-1
Organism or Cell Type:
zebrafish
Citation Extract:
van Rooij FJ, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang LC, Schmidt H, Yang ML, Chen MH, Hayes J, Johnson AD, Yanek LR, Mueller C, Lange L, Floyd JS, Ghanbari M, Zonderman AB, Jukema JW, Hofman A, van Duijn CM, Desch KC, Saba Y, Ozel AB, Snively BM, Wu JY, Schmidt R, Fornage M, Klein RJ, Fox CS, Matsuda K, Kamatani N, Wild PS, Stott DJ, Ford I, Slagboom PE, Yang J, Chu AY, Lambert AJ, Uitterlinden AG, Franco OH, Hofer E, Ginsburg D, Hu B, Keating B, Schick UM, Brody JA, Li JZ, Chen Z, Zeller T, <authors deleted - database limit> Yang Q, Psaty BM, Boerwinkle E, Becker LC, Mook-Kanamori DO, Wilson JG, Gudnason V, O'Donnell CJ, Dehghan A, Cupples LA, Nalls MA, Morris AP, Okada Y, Reiner AP, Zon LI, Ganesh SK. Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. Am J Hum Genet. 2016 Dec 19. pii: S0002-9297(16)30520-1. doi: 10.1016/j.ajhg.2016.11.016. [Epub ahead of print].

SLC44A4 Mutation Causes Autosomal Dominant Hereditary Postlingual Non-syndromic Mid-frequency Hearing loss

Authors:
Ma Z, Xia W, Liu F, Ma J, Sun S, Zhang J, Jiang N, Wang X, Hu J, Ma D
Citation:
Hum Mol Genet. 2016 Dec 23. pii: ddw394. doi: 10.1093/hmg/ddw394. [Epub ahead of print]
Epub:
Yes
Abstract:
Clinical, genetic, and functional investigations were performed to identify the causative mutation in a distinctive Chinese...
Link:
http://hmg.oxfordjournals.org/content/early/2016/12/22/hmg.ddw394.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Ma Z, Xia W, Liu F, Ma J, Sun S, Zhang J, Jiang N, Wang X, Hu J, Ma D. SLC44A4 Mutation Causes Autosomal Dominant Hereditary Postlingual Non-syndromic Mid-frequency Hearing loss. Hum Mol Genet. 2016 Dec 23. pii: ddw394. doi: 10.1093/hmg/ddw394. [Epub ahead of print].

FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy

Authors:
Begay RL, Tharp CA, Martin A, Graw SL, Sinagra G, Miani D, Sweet ME, Slavov DB, Stafford N, Zeller MJ, Alnefaie R, Rowland TJ, Brun F, Jones KL, Gowan K, Mestroni L, Garrity DM, Taylor MR
Citation:
JACC Basic Transl Sci. 2016 Aug;1(5):344-359. doi: 10.1016/j.jacbts.2016.05.004
Epub:
Not Epub
Abstract:
OBJECTIVE: To identify novel dilated cardiomyopathy (DCM) causing genes, and to elucidate the pathological mechanism leading to...
Link:
http://www.basictranslational.onlinejacc.org/content/early/2016/06/29/j.jacbts.2016.05.004
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Begay RL, Tharp CA, Martin A, Graw SL, Sinagra G, Miani D, Sweet ME, Slavov DB, Stafford N, Zeller MJ, Alnefaie R, Rowland TJ, Brun F, Jones KL, Gowan K, Mestroni L, Garrity DM, Taylor MR. FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy. JACC Basic Transl Sci. 2016 Aug;1(5):344-359. doi: 10.1016/j.jacbts.2016.05.004.

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