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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Rfx2 Stabilizes Foxj1 Binding at Chromatin Loops to Enable Multiciliated Cell Gene Expression

Authors:
Quigley IK, Kintner C
Citation:
PLoS Genet. 2017 Jan 19;13(1):e1006538. doi: 10.1371/journal.pgen.1006538
Epub:
Not Epub
Abstract:
Cooperative transcription factor binding at cis-regulatory sites in the genome drives robust eukaryotic gene expression, and...
Link:
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1006538
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Quigley IK, Kintner C. Rfx2 Stabilizes Foxj1 Binding at Chromatin Loops to Enable Multiciliated Cell Gene Expression. PLoS Genet. 2017 Jan 19;13(1):e1006538. doi: 10.1371/journal.pgen.1006538.

Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly

Authors:
Bloomekatz J, Singh R, Prall OW, Dunn AC, Vaughan M, Loo CS, Harvey RP, Yelon D
Citation:
Elife. 2017 Jan 18;6. pii: e21172. doi: 10.7554/eLife.21172. [Epub ahead of print]
Epub:
Yes
Abstract:
Communication between neighboring tissues plays a central role in guiding organ morphogenesis. During heart tube assembly,...
Link:
https://elifesciences.org/content/6/e21172
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bloomekatz J, Singh R, Prall OW, Dunn AC, Vaughan M, Loo CS, Harvey RP, Yelon D. Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly. Elife. 2017 Jan 18;6. pii: e21172. doi: 10.7554/eLife.21172. [Epub ahead of print].

The Nedd4 binding protein 3 is required for anterior neural development in Xenopus laevis

Authors:
Kiem LM, Dietmann P, Linnemann A, Schmeisser MJ, Kühl SJ
Citation:
Dev Biol. 2017 Jan 16. pii: S0012-1606(16)30546-2. doi: 10.1016/j.ydbio.2017.01.009. [Epub ahead of print]
Epub:
Yes
Abstract:
The Fezzin family member Nedd4-binding protein 3 (N4BP3) is known to regulate axonal and dendritic branching. Here, we show...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616305462
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kiem LM, Dietmann P, Linnemann A, Schmeisser MJ, Kühl SJ. The Nedd4 binding protein 3 is required for anterior neural development in Xenopus laevis. Dev Biol. 2017 Jan 16. pii: S0012-1606(16)30546-2. doi: 10.1016/j.ydbio.2017.01.009. [Epub ahead of print].

Nkx2.5 regulates Endothelin Converting Enzyme-1 during pharyngeal arch patterning

Authors:
Iklé JM, Tavares AL, King M, Ding H, Colombo S, Firulli BA, Fiulli AB, Targoff KL, Yelon D, Clouthier DE
Citation:
Genesis. 2017 Jan 20. doi: 10.1002/dvg.23021. [Epub ahead of print]
Epub:
Yes
Abstract:
In gnathostomes, dorsoventral (D-V) patterning of neural crest cells (NCC) within the pharyngeal arches is crucial for the...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dvg.23021/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Iklé JM, Tavares AL, King M, Ding H, Colombo S, Firulli BA, Fiulli AB, Targoff KL, Yelon D, Clouthier DE. Nkx2.5 regulates Endothelin Converting Enzyme-1 during pharyngeal arch patterning. Genesis. 2017 Jan 20. doi: 10.1002/dvg.23021. [Epub ahead of print].

ETS transcription factors Etv2 and Fli1b are required for tumor angiogenesis

Authors:
Baltrunaite K, Craig MP, Palencia Desai S, Chaturvedi P, Pandey RN, Hegde RS, Sumanas S
Citation:
Angiogenesis. 2017 Jan 20. doi: 10.1007/s10456-017-9539-8. [Epub ahead of print]
Epub:
Yes
Abstract:
ETS transcription factor ETV2/Etsrp functions as a key regulator of embryonic vascular development in multiple vertebrates....
Link:
http://link.springer.com/article/10.1007%2Fs10456-017-9539-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Baltrunaite K, Craig MP, Palencia Desai S, Chaturvedi P, Pandey RN, Hegde RS, Sumanas S. ETS transcription factors Etv2 and Fli1b are required for tumor angiogenesis. Angiogenesis. 2017 Jan 20. doi: 10.1007/s10456-017-9539-8. [Epub ahead of print].

Proliferation-independent regulation of organ size by Fgf/Notch signaling

Authors:
Kozlovskaja-Gumbrienė A, Yi R, Alexander R, Aman A, Jiskra R, Nagelberg D, Knaut H, McClain M, Piotrowski T
Citation:
Elife. 2017 Jan 13;6. pii: e21049. doi: 10.7554/eLife.21049
Epub:
Not Epub
Abstract:
Organ morphogenesis depends on the precise orchestration of cell migration, cell shape changes and cell adhesion. We...
Link:
https://elifesciences.org/content/6/e21049
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kozlovskaja-Gumbrienė A, Yi R, Alexander R, Aman A, Jiskra R, Nagelberg D, Knaut H, McClain M, Piotrowski T. Proliferation-independent regulation of organ size by Fgf/Notch signaling. Elife. 2017 Jan 13;6. pii: e21049. doi: 10.7554/eLife.21049.

Spinal cord regeneration in Xenopus laevis

Authors:
Edwards-Faret G, Muñoz R, Méndez-Olivos EE, Lee-Liu D, Tapia VS, Larraín J
Citation:
Nat Protoc. 2017 Feb;12(2):372-389. doi: 10.1038/nprot.2016.177
Epub:
Not Epub
Abstract:
Here we present a protocol for the husbandry of Xenopus laevis tadpoles and froglets, and procedures to study spinal cord...
Link:
http://www.nature.com/nprot/journal/v12/n2/full/nprot.2016.177.html
Delivery Method:
electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Edwards-Faret G, Muñoz R, Méndez-Olivos EE, Lee-Liu D, Tapia VS, Larraín J. Spinal cord regeneration in Xenopus laevis. Nat Protoc. 2017 Feb;12(2):372-389. doi: 10.1038/nprot.2016.177.

Dual Functional Roles of Molecular Beacon: a MicroRNA Detector and Inhibitor

Authors:
Li WM, Chan CM, Miller AL, Lee CH
Citation:
J Biol Chem. 2017 Jan 18. pii: jbc.M116.765776. doi: 10.1074/jbc.M116.765776. [Epub ahead of print]
Epub:
Yes
Abstract:
MicroRNAs are essential in many cellular processes. The ability to detect microRNAs is important for understanding its function...
Link:
http://www.jbc.org/content/early/2017/01/18/jbc.M116.765776.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li WM, Chan CM, Miller AL, Lee CH. Dual Functional Roles of Molecular Beacon: a MicroRNA Detector and Inhibitor. J Biol Chem. 2017 Jan 18. pii: jbc.M116.765776. doi: 10.1074/jbc.M116.765776. [Epub ahead of print].

Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing

Authors:
Lardelli RM, Schaffer AE, Eggens VR, Zaki MS, Grainger S, Sathe S, Van Nostrand EL, Schlachetzki Z, Rosti B, Akizu N, Scott E, Silhavy JL, Heckman LD, Rosti RO, Dikoglu E, Gregor A, Guemez-Gamboa A, Musaev D, Mande R, Widjaja A, Shaw TL, Markmiller S, Marin-Valencia I, Davies JH, de Meirleir L, Kayserili H, Altunoglu U, Freckmann ML, Warwick L, Chitayat D, Blaser S, Çağlayan AO, Bilguvar K, Per H, Fagerberg C, Christesen HT, Kibaek M, Aldinger KA, Manchester D, Matsumoto N, Muramatsu K, Saitsu H, Shiina M, Ogata K, Foulds N, Dobyns WB, Chi NC, Traver D, Spaccini L, Bova SM, Gabriel SB, Gunel M, Valente EM, Nassogne MC, Bennett EJ, Yeo GW, Baas F, Lykke-Andersen J, Gleeson JG
Citation:
Nat Genet. 2017 Jan 16. doi: 10.1038/ng.3762. [Epub ahead of print]
Epub:
Yes
Abstract:
Deadenylases are best known for degrading the poly(A) tail during mRNA decay. The deadenylase family has expanded throughout...
Link:
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3762.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lardelli RM, Schaffer AE, Eggens VR, Zaki MS, Grainger S, Sathe S, Van Nostrand EL, Schlachetzki Z, Rosti B, Akizu N, Scott E, Silhavy JL, Heckman LD, Rosti RO, Dikoglu E, Gregor A, Guemez-Gamboa A, Musaev D, Mande R, Widjaja A, Shaw TL, Markmiller S, Marin-Valencia I, Davies JH, de Meirleir L, Kayserili H, Altunoglu U, Freckmann ML, Warwick L, Chitayat D, Blaser S, Çağlayan AO, Bilguvar K, Per H, Fagerberg C, Christesen HT, Kibaek M, Aldinger KA, Manchester D, Matsumoto N, Muramatsu K, Saitsu H, Shiina M, Ogata K, Foulds N, Dobyns WB, Chi NC, Traver D, Spaccini L, Bova SM, Gabriel SB, Gunel M, Valente EM, Nassogne MC, Bennett EJ, Yeo GW, Baas F, Lykke-Andersen J, Gleeson JG. Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing. Nat Genet. 2017 Jan 16. doi: 10.1038/ng.3762. [Epub ahead of print].

A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors

Authors:
Bryant DM, Johnson K, DiTommaso T, Tickle T, Couger MB, Payzin-Dogru D, Lee TJ, Leigh ND, Kuo TH, Davis FG, Bateman J, Bryant S, Guzikowski AR, Tsai SL, Coyne S, Ye WW, Freeman RM Jr, Peshkin L, Tabin CJ, Regev A, Haas BJ, Whited JL
Citation:
Cell Rep. 2017 Jan 17;18(3):762-776. doi: 10.1016/j.celrep.2016.12.063
Epub:
Not Epub
Abstract:
Mammals have extremely limited regenerative capabilities; however, axolotls are profoundly regenerative and can replace entire...
Link:
http://www.cell.com/cell-reports/abstract/S2211-1247(16)31770-3
Delivery Method:
electroporation
Organism or Cell Type:
Ambystoma mexicanum (Axolotl)
Citation Extract:
Bryant DM, Johnson K, DiTommaso T, Tickle T, Couger MB, Payzin-Dogru D, Lee TJ, Leigh ND, Kuo TH, Davis FG, Bateman J, Bryant S, Guzikowski AR, Tsai SL, Coyne S, Ye WW, Freeman RM Jr, Peshkin L, Tabin CJ, Regev A, Haas BJ, Whited JL. A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors. Cell Rep. 2017 Jan 17;18(3):762-776. doi: 10.1016/j.celrep.2016.12.063.

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