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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors

Authors:
Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee H-Y, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, Agarwal S, Ebert BL, Gazda HT, Lodish HF, Sieff CA, Schlaeger TM, Zon LI, Daley GQ
Citation:
Science Transl Med. 2017;9(376). doi:10.1126/scitranslmed.aah5645
Epub:
Not Epub
Abstract:
Diamond-Blackfan anemia (DBA) is a congenital disorder characterized by the failure of erythroid progenitor differentiation,...
Link:
http://stm.sciencemag.org/content/9/376/eaah5645.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee H-Y, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, Agarwal S, Ebert BL, Gazda HT, Lodish HF, Sieff CA, Schlaeger TM, Zon LI, Daley GQ. Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors. Science Transl Med. 2017;9(376). doi:10.1126/scitranslmed.aah5645.

DM-GRASP/ALCAM/CD166 is required for cardiac morphogenesis and maintenance of cardiac identity in first heart field derived cells

Authors:
Gessert S, Maurus D, Brade T, Walther P, Pandur P, Kühl M
Citation:
Dev Biol. 2008 Sep 1;321(1):150-61. doi: 10.1016/j.ydbio.2008.06.013
Epub:
Not Epub
Abstract:
Vertebrate heart development requires specification of cardiac precursor cells, migration of cardiac progenitors as well as...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160608010038
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gessert S, Maurus D, Brade T, Walther P, Pandur P, Kühl M. DM-GRASP/ALCAM/CD166 is required for cardiac morphogenesis and maintenance of cardiac identity in first heart field derived cells. Dev Biol. 2008 Sep 1;321(1):150-61. doi: 10.1016/j.ydbio.2008.06.013.

Tbx2 regulates anterior neural specification by repressing FGF signaling pathway

Authors:
Cho GS, Park DS, Choi SC, Han JK
Citation:
Dev Biol. 2017 Jan 15;421(2):183-193. doi: 10.1016/j.ydbio.2016.11.020
Epub:
Not Epub
Abstract:
During early embryogenesis, FGF signals regulate the antero-posterior (AP) patterning of the neural plate by promoting...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616303402
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Cho GS, Park DS, Choi SC, Han JK. Tbx2 regulates anterior neural specification by repressing FGF signaling pathway. Dev Biol. 2017 Jan 15;421(2):183-193. doi: 10.1016/j.ydbio.2016.11.020.

RhoA regulates actin network dynamics during apical surface emergence in multiciliated epithelial cells

Authors:
Sedzinski J, Hannezo E, Tu F, Biro M, Wallingford JB
Citation:
J Cell Sci. 2017 Jan 15;130(2):420-428. doi: 10.1242/jcs.194704
Epub:
Not Epub
Abstract:
Homeostatic replacement of epithelial cells from basal precursors is a multistep process involving progenitor cell...
Link:
http://jcs.biologists.org/content/130/2/420
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Sedzinski J, Hannezo E, Tu F, Biro M, Wallingford JB. RhoA regulates actin network dynamics during apical surface emergence in multiciliated epithelial cells. J Cell Sci. 2017 Jan 15;130(2):420-428. doi: 10.1242/jcs.194704.

An exclusive cellular and molecular network governs intestinal smooth muscle cell differentiation in vertebrates

Authors:
Gays D, Hess C, Camporeale A, Ala U, Provero P, Mosimann C, Santoro MM
Citation:
Development. 2017 Feb 1;144(3):464-478. doi: 10.1242/dev.133926
Epub:
Not Epub
Abstract:
Intestinal smooth muscle cells (iSMCs) are a crucial component of the adult gastrointestinal tract and support intestinal...
Link:
http://dev.biologists.org/content/144/3/464
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gays D, Hess C, Camporeale A, Ala U, Provero P, Mosimann C, Santoro MM. An exclusive cellular and molecular network governs intestinal smooth muscle cell differentiation in vertebrates. Development. 2017 Feb 1;144(3):464-478. doi: 10.1242/dev.133926.

USP40 gene knockdown disrupts glomerular permeability in zebrafish

Authors:
Takagi H, Nishibori Y, Katayama K, Katada T, Takahashi S, Kiuchi Z, Takahashi SI, Kamei H, Kawakami H, Akimoto Y, Kudo A, Asanuma K, Takematsu H, Yan K
Citation:
Am J Physiol Renal Physiol. 2017 Feb 1:ajprenal.00197.2016. doi: 10.1152/ajprenal.00197.2016. [Epub ahead of print]
Epub:
Yes
Abstract:
Unbiased transcriptome profiling and functional genomics approaches have identified ubiquitin specific protease 40 (USP40) as a...
Link:
http://ajprenal.physiology.org/content/early/2017/01/25/ajprenal.00197.2016
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Takagi H, Nishibori Y, Katayama K, Katada T, Takahashi S, Kiuchi Z, Takahashi SI, Kamei H, Kawakami H, Akimoto Y, Kudo A, Asanuma K, Takematsu H, Yan K. USP40 gene knockdown disrupts glomerular permeability in zebrafish. Am J Physiol Renal Physiol. 2017 Feb 1:ajprenal.00197.2016. doi: 10.1152/ajprenal.00197.2016. [Epub ahead of print].

Vegfd modulates both angiogenesis and lymphangiogenesis during zebrafish embryonic development

Authors:
Bower NI, Vogrin AJ, Le Guen L, Chen H, Stacker SA, Achen MG, Hogan BM
Citation:
Development. 2017 Feb 1;144(3):507-518. doi: 10.1242/dev.146969
Epub:
Not Epub
Abstract:
Vascular endothelial growth factors (VEGFs) control angiogenesis and lymphangiogenesis during development and in pathological...
Link:
http://dev.biologists.org/content/144/3/507
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bower NI, Vogrin AJ, Le Guen L, Chen H, Stacker SA, Achen MG, Hogan BM. Vegfd modulates both angiogenesis and lymphangiogenesis during zebrafish embryonic development. Development. 2017 Feb 1;144(3):507-518. doi: 10.1242/dev.146969.

miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA

Authors:
Bellon A, Iyer A, Bridi S, Lee FC, Ovando-Vázquez C, Corradi E, Longhi S, Roccuzzo M, Strohbuecker S, Naik S, Sarkies P, Miska E, Abreu-Goodger C, Holt CE, Baudet ML
Citation:
Cell Rep. 2017 Jan 31;18(5):1171-1186. doi: 10.1016/j.celrep.2016.12.093
Epub:
Not Epub
Abstract:
During brain wiring, cue-induced axon behaviors such as directional steering and branching are aided by localized mRNA...
Link:
http://www.cell.com/cell-reports/fulltext/S2211-1247(17)30003-7
Delivery Method:
microinjection, electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bellon A, Iyer A, Bridi S, Lee FC, Ovando-Vázquez C, Corradi E, Longhi S, Roccuzzo M, Strohbuecker S, Naik S, Sarkies P, Miska E, Abreu-Goodger C, Holt CE, Baudet ML. miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA. Cell Rep. 2017 Jan 31;18(5):1171-1186. doi: 10.1016/j.celrep.2016.12.093.

Amplified pathogenic actions of angiotensin II in cysteine-rich LIM-only protein 4-negative mouse hearts

Authors:
Straubinger J, Boldt K, Kuret A, Deng L, Krattenmacher D, Bork N, Desch M, Feil R, Feil S, Nemer M, Ueffing M, Ruth P, Just S, Lukowski R
Citation:
FASEB J. 2017 Jan 30. pii: fj.201601186. doi: 10.1096/fj.201601186. [Epub ahead of print]
Epub:
Yes
Abstract:
LIM domain proteins have been identified as essential modulators of cardiac biology and pathology; however, it is unclear which...
Link:
http://www.fasebj.org/content/early/2017/01/30/fj.201601186.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Straubinger J, Boldt K, Kuret A, Deng L, Krattenmacher D, Bork N, Desch M, Feil R, Feil S, Nemer M, Ueffing M, Ruth P, Just S, Lukowski R. Amplified pathogenic actions of angiotensin II in cysteine-rich LIM-only protein 4-negative mouse hearts. FASEB J. 2017 Jan 30. pii: fj.201601186. doi: 10.1096/fj.201601186. [Epub ahead of print].

Inhibition of Pseudomonas aeruginosa by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers

Authors:
Howard JJ, Sturge CR, Moustafa DA, Daly SM, Marshall-Batty KR, Felder CF, Zamora D, Yabe-Gill M, Labandeira-Rey M, Bailey SM, Wong M, Goldberg JB, Geller BL, Greenberg DE
Citation:
Antimicrob Agents Chemother. 2017 Jan 30. pii: AAC.01938-16. doi: 10.1128/AAC.01938-16. [Epub ahead of print]
Epub:
Yes
Abstract:
Pseudomonas aeruginosa is a highly virulent, multidrug-resistant pathogen that causes significant morbidity and mortality in...
Link:
http://aac.asm.org/content/early/2017/01/24/AAC.01938-16.abstract
Delivery Method:
peptide-linked
Organism or Cell Type:
Pseudomonas aeruginosa
Citation Extract:
Howard JJ, Sturge CR, Moustafa DA, Daly SM, Marshall-Batty KR, Felder CF, Zamora D, Yabe-Gill M, Labandeira-Rey M, Bailey SM, Wong M, Goldberg JB, Geller BL, Greenberg DE. Inhibition of Pseudomonas aeruginosa by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers. Antimicrob Agents Chemother. 2017 Jan 30. pii: AAC.01938-16. doi: 10.1128/AAC.01938-16. [Epub ahead of print].

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