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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Flotillins control zebrafish epiboly through their role in cadherin-mediated cell-cell adhesion

Authors:
Morris EA, Bodin S, Delaval B, Comunale F, Georget V, Costa ML, Lutfalla G, Gauthier-Rouvière C
Citation:
Biol Cell. 2017 Feb 22. doi: 10.1111/boc.201700001. [Epub ahead of print]
Epub:
Yes
Abstract:
Zebrafish gastrulation and particularly epiboly that involves coordinated movements of several cell layers is a dynamic process...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Morris EA, Bodin S, Delaval B, Comunale F, Georget V, Costa ML, Lutfalla G, Gauthier-Rouvière C. Flotillins control zebrafish epiboly through their role in cadherin-mediated cell-cell adhesion. Biol Cell. 2017 Feb 22. doi: 10.1111/boc.201700001. [Epub ahead of print].

Long-term behavioral change as a result of acute ethanol exposure in zebrafish: Evidence for a role for sonic hedgehog but not retinoic acid signaling

Authors:
Burton D, Zhang C, Boa-Amponsem O, Mackinnon S, Cole GJ
Citation:
Neurotoxicol Teratol. 2017 Feb 18. pii: S0892-0362(16)30128-3. doi: 10.1016/j.ntt.2017.01.006. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Developmental exposure to ethanol is recognized to produce long-term neurobehavioral impairment in multiple animal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Burton D, Zhang C, Boa-Amponsem O, Mackinnon S, Cole GJ. Long-term behavioral change as a result of acute ethanol exposure in zebrafish: Evidence for a role for sonic hedgehog but not retinoic acid signaling. Neurotoxicol Teratol. 2017 Feb 18. pii: S0892-0362(16)30128-3. doi: 10.1016/j.ntt.2017.01.006. [Epub ahead of print].

Transient knock-down of kcna2 reduces sleep in larval zebrafish

Authors:
Srdanovic S, Þorsteinsson H, FriÐriksson Þ, Pétursson SÓ, Maier VH, Karlsson KÆ
Citation:
Behav Brain Res. 2017 Feb 18. pii: S0166-4328(16)30882-8. doi: 10.1016/j.bbr.2017.02.026. [Epub ahead of print]
Epub:
Yes
Abstract:
In the current study we set out to determine the effects of morpholino oligonucleotide (MO) knock-down of kcna2 on sleep-wake...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Srdanovic S, Þorsteinsson H, FriÐriksson Þ, Pétursson SÓ, Maier VH, Karlsson KÆ. Transient knock-down of kcna2 reduces sleep in larval zebrafish. Behav Brain Res. 2017 Feb 18. pii: S0166-4328(16)30882-8. doi: 10.1016/j.bbr.2017.02.026. [Epub ahead of print].

Leftward Flow Determines Laterality in Conjoined Twins

Authors:
Tisler M, Thumberger T, Schneider I, Schweickert A, Blum M
Citation:
Curr Biol. 2017 Feb 20;27(4):543-548. doi: 10.1016/j.cub.2016.12.049
Epub:
Not Epub
Abstract:
Conjoined twins fused at the thorax display an enigmatic left-right defect: although left twins are normal, laterality is...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tisler M, Thumberger T, Schneider I, Schweickert A, Blum M. Leftward Flow Determines Laterality in Conjoined Twins. Curr Biol. 2017 Feb 20;27(4):543-548. doi: 10.1016/j.cub.2016.12.049.

A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse

Authors:
Ulmer B, Tingler M, Kurz S, Maerker M, Andre P, Mönch D, Campione M, Deißler K, Lewandoski M, Thumberger T, Schweickert A, Fainsod A, Steinbeißer H, Blum M
Citation:
Sci Rep. 2017;7:43010. doi:10.1038/srep43010
Epub:
Not Epub
Abstract:
Goosecoid (Gsc) expression marks the primary embryonic organizer in vertebrates and beyond. While functions have been assigned...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ulmer B, Tingler M, Kurz S, Maerker M, Andre P, Mönch D, Campione M, Deißler K, Lewandoski M, Thumberger T, Schweickert A, Fainsod A, Steinbeißer H, Blum M. A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse. Sci Rep. 2017;7:43010. doi:10.1038/srep43010.

Vegfa Impacts Early Myocardium Development in Zebrafish

Authors:
Zhu D, Fang Y, Gao K, Shen J, Zhong TP, Li F
Citation:
Int J Mol Sci. 2017;18(2):444 doi:10.3390/ijms18020444
Epub:
Not Epub
Abstract:
Vascular endothelial growth factor A (Vegfa) signaling regulates cardiovascular development. However, the cellular mechanisms...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhu D, Fang Y, Gao K, Shen J, Zhong TP, Li F. Vegfa Impacts Early Myocardium Development in Zebrafish. Int J Mol Sci. 2017;18(2):444 doi:10.3390/ijms18020444.

Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation

Authors:
Liu Y, Sepich DS, Solnica-Krezel L
Citation:
PLoS Genet. 2017;13(2):e1006564. doi:10.1371/journal.pgen.1006564
Epub:
Not Epub
Abstract:
Cell proliferation has generally been considered dispensable for anteroposterior extension of embryonic axis during vertebrate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu Y, Sepich DS, Solnica-Krezel L. Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation. PLoS Genet. 2017;13(2):e1006564. doi:10.1371/journal.pgen.1006564.

A girl with developmental delay, ataxia, cranial nerve palsies, severe respiratory problems in infancy-Expanding NDST1 syndrome

Authors:
Armstrong L, Tarailo-Graovac M, Sinclair G, Seath KI, Wasserman WW, Ross CJ, van Karnebeek CD
Citation:
Am J Med Genet A. 2017 Mar;173(3):712-715. doi: 10.1002/ajmg.a.37621
Epub:
Not Epub
Abstract:
NDST1 encodes an enzyme involved in the first steps in the synthesis of heparan sulfate chains, proteoglycans that are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Armstrong L, Tarailo-Graovac M, Sinclair G, Seath KI, Wasserman WW, Ross CJ, van Karnebeek CD. A girl with developmental delay, ataxia, cranial nerve palsies, severe respiratory problems in infancy-Expanding NDST1 syndrome. Am J Med Genet A. 2017 Mar;173(3):712-715. doi: 10.1002/ajmg.a.37621.

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions

Authors:
Range RC, Martinez-Bartolomé M, Burr SD
Citation:
J Vis Exp. 2017;120:e55113. doi:10.3791/55113
Epub:
Not Epub
Abstract:
Remarkably few cell-to-cell signal transduction pathways are necessary during embryonic development to generate the large...
Organism or Cell Type:
sea urchin
Citation Extract:
Range RC, Martinez-Bartolomé M, Burr SD. The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions. J Vis Exp. 2017;120:e55113. doi:10.3791/55113.

Hyaluronic acid synthesis is required for zebrafish tail fin regeneration

Authors:
Ouyang X, Panetta NJ, Talbott MD, Payumo AY, Halluin C, Longaker MT, Chen JK
Citation:
PLoS One. 2017 Feb 16;12(2):e0171898. doi: 10.1371/journal.pone.0171898
Epub:
Not Epub
Abstract:
Using genome-wide transcriptional profiling and whole-mount expression analyses of zebrafish larvae, we have identified...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ouyang X, Panetta NJ, Talbott MD, Payumo AY, Halluin C, Longaker MT, Chen JK. Hyaluronic acid synthesis is required for zebrafish tail fin regeneration. PLoS One. 2017 Feb 16;12(2):e0171898. doi: 10.1371/journal.pone.0171898.

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