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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
The pro-inflammatory signalling regulator Stat4 promotes vasculogenesis of great vessels derived from endothelial precursors
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Citation:
Nat Comm. 2017;8:14640 doi:10.1038/ncomms14640 Epub:
Not Epub Abstract:
Vasculogenic defects of great vessels (GVs) are a major cause of congenital cardiovascular diseases. However, genetic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Meng Z-Z, Liu W, Xia Y, Yin H-M, Zhang C-Y, Su D, Yan L-F, Gu A-H, Zhou Y. The pro-inflammatory signalling regulator Stat4 promotes vasculogenesis of great vessels derived from endothelial precursors. Nat Comm. 2017;8:14640 doi:10.1038/ncomms14640. |
Sox10 contributes to the balance of fate choice in dorsal root ganglion progenitors
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Citation:
PLoS One. 2017 Mar 2;12(3):e0172947. doi: 10.1371/journal.pone.0172947 Epub:
Not Epub Abstract:
The development of functional peripheral ganglia requires a balance of specification of both neuronal and glial components. In... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Delfino-Machín M, Madelaine R, Busolin G, Nikaido M, Colanesi S, Camargo-Sosa K, Law EW, Toppo S, Blader P, Tiso N, Kelsh RN. Sox10 contributes to the balance of fate choice in dorsal root ganglion progenitors. PLoS One. 2017 Mar 2;12(3):e0172947. doi: 10.1371/journal.pone.0172947. |
Using Morpholinos to Control Gene Expression
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Citation:
Curr Protoc Nucleic Acid Chem. 2017 Mar 2;68:4.30.1-4.30.29. doi: 10.1002/cpnc.21 Epub:
Not Epub Abstract:
Morpholino oligonucleotides are stable, uncharged, water-soluble molecules used to block complementary sequences of RNA,... Citation Extract: Moulton JD. Using Morpholinos to Control Gene Expression. Curr Protoc Nucleic Acid Chem. 2017 Mar 2;68:4.30.1-4.30.29. doi: 10.1002/cpnc.21. |
tomm22 knockdown-mediated hepatocyte damages elicit both the formation of hybrid hepatocytes and biliary conversion to hepatocytes in zebrafish larvae
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Citation:
Gene Expr. 2017 Mar 1. doi: 10.3727/105221617X695195. [Epub ahead of print] Epub:
Yes Abstract:
The liver has a highly regenerative capacity. In the normal liver, hepatocytes proliferate to restore lost liver mass. However... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu J, Choi TY, Shin D. tomm22 knockdown-mediated hepatocyte damages elicit both the formation of hybrid hepatocytes and biliary conversion to hepatocytes in zebrafish larvae. Gene Expr. 2017 Mar 1. doi: 10.3727/105221617X695195. [Epub ahead of print]. |
Myeloid and erythroid hematopoietic transcription factor expression decline after knockdown of lmna genes in zebrafish embryos
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Citation:
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2016 May 25;45(6):620-625. Chinese Epub:
Not Epub Abstract:
Objective: To investigate the effect of lmna gene down-regulation on early hematopoietic development of zebrafish. Methods:... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hou S, Wang Z, Wang J, He Z, Shu L. Myeloid and erythroid hematopoietic transcription factor expression decline after knockdown of lmna genes in zebrafish embryos. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2016 May 25;45(6):620-625. Chinese. |
R-spondin 1 is required for specification of hematopoietic stem cells through Wnt16 and Vegfa signaling pathways
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Citation:
Development. 2017 Feb 15;144(4):590-600. doi: 10.1242/dev.139956 Epub:
Not Epub Abstract:
Hematopoietic stem cells (HSCs) are the therapeutic component of bone marrow transplants, but finding immune-compatible donors... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Genthe JR, Clements WK. R-spondin 1 is required for specification of hematopoietic stem cells through Wnt16 and Vegfa signaling pathways. Development. 2017 Feb 15;144(4):590-600. doi: 10.1242/dev.139956. |
How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse
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Citation:
Hum Mol Genet. 2015 Aug 1;24(15):4225-37. doi: 10.1093/hmg/ddv155 Epub:
Not Epub Abstract:
Splice modulation therapy has shown great clinical promise in Duchenne muscular dystrophy, resulting in the production of... Delivery Method:
peptide-linked Organism or Cell Type:
mouse mdx Citation Extract: Godfrey C, Muses S, McClorey G, Wells KE, Coursindel T, Terry RL, Betts C, Hammond S, O'Donovan L, Hildyard J, El Andaloussi S, Gait MJ, Wood MJ, Wells DJ. How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse. Hum Mol Genet. 2015 Aug 1;24(15):4225-37. doi: 10.1093/hmg/ddv155. |
Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation
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Citation:
Nat Microbio. 2017;2:17022. doi:10.1038/nmicrobiol.2017.22 Epub:
Not Epub Abstract:
Retinoic acid-inducible gene I (RIG-I) receptor recognizes 5′-triphosphorylated RNA and triggers a signalling cascade that... Delivery Method:
peptide-linked Organism or Cell Type:
mice C57BL/6 Citation Extract: Soonthornvacharin S, Rodriguez-Frandsen A, Zhou Y, Galvez F, Huffmaster NJ, Tripathi S, Balasubramaniam VRMT, Inoue A, de Castro E, Moulton H, Stein DA, Sánchez-Aparicio MT, De Jesus PD, Nguyen Q, König R, Krogan NJ, García-Sastre A, Yoh SM, Chanda SK. Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation. Nat Microbio. 2017;2:17022. doi:10.1038/nmicrobiol.2017.22. |
Dynamics of ASC speck formation during skin inflammatory responses in vivo
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Citation:
bioRxiv. 2017. doi:10.1101/111542 Epub:
Yes Abstract:
Activated danger or pathogen sensors trigger assembly of the inflammasome adaptor ASC into specks, large signalling platforms... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rodriguez PSK, Schieber N, Thumberger T, Wittbrodt J, Schwab Y, Leptin M. Dynamics of ASC speck formation during skin inflammatory responses in vivo. bioRxiv. 2017. doi:10.1101/111542. |
Stomach curvature is generated by left-right asymmetric gut morphogenesis
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Citation:
Development, 2017;[Epub ahead of print] doi: 10.1242/dev.143701 Epub:
Yes Abstract:
Left-right (LR) asymmetry is a fundamental feature of internal anatomy, yet the emergence of morphological asymmetry remains... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Davis A, Amin NM, Johnson C, Bagley K, Ghashghaei HT, Nascone-Yoder N. Stomach curvature is generated by left-right asymmetric gut morphogenesis. Development, 2017;[Epub ahead of print] doi: 10.1242/dev.143701. |