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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Paxillin Genes and Actomyosin Contractility Regulate Myotome Morphogenesis in Zebrafish

Authors:
Jacob AE, Amack JD, Turner CE
Citation:
Dev Biol. 2017 Mar 14. pii: S0012-1606(16)30694-7. doi: 10.1016/j.ydbio.2017.03.012. [Epub ahead of print]
Epub:
Yes
Abstract:
Paxillin (Pxn) is a key adapter protein and signaling regulator at sites of cell-extracellular matrix (ECM) adhesion. Here, we...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jacob AE, Amack JD, Turner CE. Paxillin Genes and Actomyosin Contractility Regulate Myotome Morphogenesis in Zebrafish. Dev Biol. 2017 Mar 14. pii: S0012-1606(16)30694-7. doi: 10.1016/j.ydbio.2017.03.012. [Epub ahead of print].

Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine

Authors:
Xu J, Lu Z, Narayan A, Le Rouzic VP, Xu M, Hunkele A, Brown TG, Hoefer WF, Rossi GC, Rice RC, Martínez-Rivera A, Rajadhyaksha AM, Cartegni L, Bassoni DL, Pasternak GW, Pan Y-X
Citation:
J Clin Invest. 2017;[Epub ahead of print] doi:10.1172/JCI88760
Epub:
Yes
Abstract:
Extensive 3′ alternative splicing of the mu opioid receptor gene OPRM1 creates multiple C-terminal splice variants. However,...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse
Citation Extract:
Xu J, Lu Z, Narayan A, Le Rouzic VP, Xu M, Hunkele A, Brown TG, Hoefer WF, Rossi GC, Rice RC, Martínez-Rivera A, Rajadhyaksha AM, Cartegni L, Bassoni DL, Pasternak GW, Pan Y-X. Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine. J Clin Invest. 2017;[Epub ahead of print] doi:10.1172/JCI88760.

Cytoskeleton-associated protein 5 and clathrin heavy chain binding regulates spindle assembly in mouse oocytes

Authors:
Lu A, Zhou CJ, Wang DH, Han Z, Kong XW, Ma YZ, Yun ZZ, Liang CG
Citation:
Oncotarget. 2017 Feb 4. doi: 10.18632/oncotarget.15097. [Epub ahead of print]
Epub:
Yes
Abstract:
Mammalian oocyte meiotic maturation is the precondition of early embryo development. Lots of microtubules (MT)-associated...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Lu A, Zhou CJ, Wang DH, Han Z, Kong XW, Ma YZ, Yun ZZ, Liang CG. Cytoskeleton-associated protein 5 and clathrin heavy chain binding regulates spindle assembly in mouse oocytes. Oncotarget. 2017 Feb 4. doi: 10.18632/oncotarget.15097. [Epub ahead of print].

Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy

Authors:
Powis RA, Karyka E, Boyd P, Côme J, Jones RA, Zheng Y, Szunyogova E, Groen EJ, Hunter G, Thomson D, Wishart TM, Becker CG, Parson SH, Martinat C, Azzouz M, Gillingwater TH
Citation:
JCI Insight. 2016 Jul 21;1(11):e87908
Epub:
Not Epub
Abstract:
The autosomal recessive neuromuscular disease spinal muscular atrophy (SMA) is caused by loss of survival motor neuron (SMN)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Powis RA, Karyka E, Boyd P, Côme J, Jones RA, Zheng Y, Szunyogova E, Groen EJ, Hunter G, Thomson D, Wishart TM, Becker CG, Parson SH, Martinat C, Azzouz M, Gillingwater TH. Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy. JCI Insight. 2016 Jul 21;1(11):e87908.

c-Src Suppresses Dendritic Cell Antitumor Activity via T Cell Ig and Mucin Protein-3 Receptor

Authors:
Gujar R, Maurya N, Yadav V, Gupta M, Arora S, Khatri N, Sen P
Citation:
J Immunol. 2016 Sep 1;197(5):1650-62. doi: 10.4049/jimmunol.1600104
Epub:
Not Epub
Abstract:
The enhanced expression of T cell Ig and mucin protein-3 (TIM-3) on tumor-associated dendritic cells (DCs) attenuates antitumor...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice (B6 and BALB/c)
Citation Extract:
Gujar R, Maurya N, Yadav V, Gupta M, Arora S, Khatri N, Sen P. c-Src Suppresses Dendritic Cell Antitumor Activity via T Cell Ig and Mucin Protein-3 Receptor. J Immunol. 2016 Sep 1;197(5):1650-62. doi: 10.4049/jimmunol.1600104.

Annexin A6 controls neuronal membrane dynamics throughout chick cranial sensory gangliogenesis

Authors:
Shah A, Schiffmacher AT, Taneyhill LA
Citation:
Dev Biol. 2017;[Epub ahead of print] doi:10.1016/j.ydbio.2017.03.011
Epub:
Yes
Abstract:
Cranial sensory ganglia are components of the peripheral nervous system that possess a significant somatosensory role and...
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Shah A, Schiffmacher AT, Taneyhill LA. Annexin A6 controls neuronal membrane dynamics throughout chick cranial sensory gangliogenesis. Dev Biol. 2017;[Epub ahead of print] doi:10.1016/j.ydbio.2017.03.011.

Glutathione peroxidase 4 inhibits Wnt/β-catenin signaling and regulates dorsal organizer formation in zebrafish embryos

Authors:
Rong X, Zhou Y, Liu Y, Zhao B, Wang B, Wang C, Gong X, Tang P, Lu L, Li Y, Zhao C, Zhou J
Citation:
Development. 2017;[Epub ahead of print] doi:10.1242/dev.144261
Epub:
Yes
Abstract:
The Wnt/β-catenin signaling pathway plays pivotal roles in axis formation during embryogenesis and in adult tissue homeostasis...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rong X, Zhou Y, Liu Y, Zhao B, Wang B, Wang C, Gong X, Tang P, Lu L, Li Y, Zhao C, Zhou J. Glutathione peroxidase 4 inhibits Wnt/β-catenin signaling and regulates dorsal organizer formation in zebrafish embryos. Development. 2017;[Epub ahead of print] doi:10.1242/dev.144261.

Foxh1 Occupies cis-Regulatory Modules Prior to Dynamic Transcription Factor Interactions Controlling the Mesendoderm Gene Program

Authors:
Charney RM, Forouzmand E, Cho JS, Cheung J, Paraiso KD, Yasuoka Y, Takahashi S, Taira M, Blitz IL, Xie X, Cho KWY
Citation:
Dev Cell. 2017;[Epub ahead of print] doi:10.1016/j.devcel.2017.02.017
Epub:
Yes
Abstract:
The interplay between transcription factors and chromatin dictates gene regulatory network activity. Germ layer specification...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Charney RM, Forouzmand E, Cho JS, Cheung J, Paraiso KD, Yasuoka Y, Takahashi S, Taira M, Blitz IL, Xie X, Cho KWY. Foxh1 Occupies cis-Regulatory Modules Prior to Dynamic Transcription Factor Interactions Controlling the Mesendoderm Gene Program. Dev Cell. 2017;[Epub ahead of print] doi:10.1016/j.devcel.2017.02.017.

Mutations in TMEM260 Cause a Pediatric Neurodevelopmental, Cardiac, and Renal Syndrome

Authors:
Ta-Shma A, Khan TN, Vivante A, Willer JR, Matak P, Jalas C, Pode-Shakked B, Salem Y, Anikster Y, Hildebrandt F, Katsanis N, Elpeleg O, Davis EE
Citation:
Am J Hum Genet. 2017;[Epub ahead of print] doi:10.1016/j.ajhg.2017.02.007
Epub:
Yes
Abstract:
Despite the accelerated discovery of genes associated with syndromic traits, the majority of families affected by such...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ta-Shma A, Khan TN, Vivante A, Willer JR, Matak P, Jalas C, Pode-Shakked B, Salem Y, Anikster Y, Hildebrandt F, Katsanis N, Elpeleg O, Davis EE. Mutations in TMEM260 Cause a Pediatric Neurodevelopmental, Cardiac, and Renal Syndrome. Am J Hum Genet. 2017;[Epub ahead of print] doi:10.1016/j.ajhg.2017.02.007.

The Golgi matrix protein giantin is required for normal cilia function in zebrafish

Authors:
Bergen DJM, Stevenson NL, Skinner RJ, Stephens DJ, Hammond CL
Citation:
bioRxiv. 2017;doi:https://doi.org/10.1101/117507
Epub:
Not Epub
Abstract:
The Golgi is essential for glycosylation of newly synthesised proteins including almost all cell-surface and extracellular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bergen DJM, Stevenson NL, Skinner RJ, Stephens DJ, Hammond CL. The Golgi matrix protein giantin is required for normal cilia function in zebrafish. bioRxiv. 2017;doi:https://doi.org/10.1101/117507.

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