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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Engrailed controls epaxial-hypaxial muscle innervation and the establishment of vertebrate three-dimensional mobility

Authors:
Ahmed MU, Maurya AK, Cheng L, Jorge EC, Schubert FR, Maire P, Basson MA, Ingham PW, Dietrich S
Citation:
Dev Biol. 2017 Aug 12. pii: S0012-1606(17)30416-5. doi: 10.1016/j.ydbio.2017.08.011. [Epub ahead of print]
Epub:
Yes
Abstract:
Chordates are characterised by contractile muscle on either side of the body that promotes movement by side-to-side undulation...
Organism or Cell Type:
zebrafish
Citation Extract:
Ahmed MU, Maurya AK, Cheng L, Jorge EC, Schubert FR, Maire P, Basson MA, Ingham PW, Dietrich S. Engrailed controls epaxial-hypaxial muscle innervation and the establishment of vertebrate three-dimensional mobility. Dev Biol. 2017 Aug 12. pii: S0012-1606(17)30416-5. doi: 10.1016/j.ydbio.2017.08.011. [Epub ahead of print].

A defect in the mitochondrial protein Mpv17 underlies the transparent casper zebrafish

Authors:
D'Agati G, Beltre R, Sessa A, Burger A, Zhou Y, Mosimann C, White RM
Citation:
Dev Biol. 2017 Jul 28. pii: S0012-1606(17)30373-1. doi: 10.1016/j.ydbio.2017.07.017. [Epub ahead of print]
Epub:
Yes
Abstract:
The casper strain of zebrafish is widely used in studies ranging from cancer to neuroscience. casper offers the advantage of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
D'Agati G, Beltre R, Sessa A, Burger A, Zhou Y, Mosimann C, White RM. A defect in the mitochondrial protein Mpv17 underlies the transparent casper zebrafish. Dev Biol. 2017 Jul 28. pii: S0012-1606(17)30373-1. doi: 10.1016/j.ydbio.2017.07.017. [Epub ahead of print].

Calaxin establishes basal body orientation and coordinates movement of monocilia in sea urchin embryos

Authors:
Mizuno K, Shiba K, Yaguchi J, Shibata D, Yaguchi S, Prulière G, Chenevert J, Inaba K
Citation:
Sci Rep. 2017 Sep 7;7(1):10751. doi: 10.1038/s41598-017-10822-z
Epub:
Not Epub
Abstract:
Through their coordinated alignment and beating, motile cilia generate directional fluid flow and organismal movement. While...
Delivery Method:
microinjection
Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin)
Citation Extract:
Mizuno K, Shiba K, Yaguchi J, Shibata D, Yaguchi S, Prulière G, Chenevert J, Inaba K. Calaxin establishes basal body orientation and coordinates movement of monocilia in sea urchin embryos. Sci Rep. 2017 Sep 7;7(1):10751. doi: 10.1038/s41598-017-10822-z.

Epigenetic regulation of left-right asymmetry by DNA methylation

Authors:
Wang L, Liu Z, Lin H, Ma D, Tao Q, Liu F
Citation:
EMBO J. 2017;[Epub ahead of print] doi:10.15252/embj.201796580
Epub:
Yes
Abstract:
DNA methylation is a major epigenetic modification; however, the precise role of DNA methylation in vertebrate development is...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Wang L, Liu Z, Lin H, Ma D, Tao Q, Liu F. Epigenetic regulation of left-right asymmetry by DNA methylation. EMBO J. 2017;[Epub ahead of print] doi:10.15252/embj.201796580.

PaxA, but not PaxC, is required for cnidocyte development in the sea anemone Nematostella vectensis

Authors:
Babonis LS, Martindale MQ
Citation:
Evodevo. 2017 Sep 4;8:14. doi: 10.1186/s13227-017-0077-7. eCollection 2017
Epub:
Not Epub
Abstract:
BACKGROUND: Pax genes are a family of conserved transcription factors that regulate many aspects of developmental morphogenesis...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Babonis LS, Martindale MQ. PaxA, but not PaxC, is required for cnidocyte development in the sea anemone Nematostella vectensis. Evodevo. 2017 Sep 4;8:14. doi: 10.1186/s13227-017-0077-7. eCollection 2017.

Identification of a new adtrp1-tfpi regulatory axis for the specification of primitive myelopoiesis and definitive hematopoiesis

Authors:
Wang L, Wang X, Wang L, Yousaf M, Li J, Zuo M, Yang Z, Gou D, Bao B, Li L, Xiang N, Jia H, Xu C, Chen Q, Wang QK
Citation:
FASEB J. 2017 Sep 6. pii: fj.201700166RR. doi: 10.1096/fj.201700166RR. [Epub ahead of print]
Epub:
Yes
Abstract:
A genomic variant in the human ADTRP [androgen-dependent tissue factor (TF) pathway inhibitor (TFPI) regulating protein] gene...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang L, Wang X, Wang L, Yousaf M, Li J, Zuo M, Yang Z, Gou D, Bao B, Li L, Xiang N, Jia H, Xu C, Chen Q, Wang QK. Identification of a new adtrp1-tfpi regulatory axis for the specification of primitive myelopoiesis and definitive hematopoiesis. FASEB J. 2017 Sep 6. pii: fj.201700166RR. doi: 10.1096/fj.201700166RR. [Epub ahead of print].

m6A modulates haematopoietic stem and progenitor cell specification

Authors:
Zhang C, Chen Y, Sun B, Wang L, Yang Y, Ma D, Lv J, Heng J, Ding Y, Xue Y, Lu X, Xiao W, Yang YG, Liu F
Citation:
Nature. 2017 Sep 6. doi: 10.1038/nature23883. [Epub ahead of print]
Epub:
Yes
Abstract:
N6-methyladenosine (m6A) has been identified as the most abundant modification on eukaryote messenger RNA (mRNA). Although the...
Citation Extract:
Zhang C, Chen Y, Sun B, Wang L, Yang Y, Ma D, Lv J, Heng J, Ding Y, Xue Y, Lu X, Xiao W, Yang YG, Liu F. m6A modulates haematopoietic stem and progenitor cell specification. Nature. 2017 Sep 6. doi: 10.1038/nature23883. [Epub ahead of print].

Autogenous Cross-Regulation Of Quaking mRNA Processing And Translation Balances Quaking Functions In Splicing And Translation

Authors:
Fagg WS, Liu N, Fair JH, Shiue L, Katzmann S, Donohue J-P, Ares M
Citation:
bioRxiv. 2017. doi:doi.org/10.1101/127936
Epub:
Not Epub
Abstract:
Quaking protein isoforms arise from a single Quaking gene, and bind the same RNA motif to regulate splicing, translation, decay...
Organism or Cell Type:
cell culture: mouse myoblasts
Citation Extract:
Fagg WS, Liu N, Fair JH, Shiue L, Katzmann S, Donohue J-P, Ares M. Autogenous Cross-Regulation Of Quaking mRNA Processing And Translation Balances Quaking Functions In Splicing And Translation. bioRxiv. 2017. doi:doi.org/10.1101/127936.

Endodermal germ-layer formation through active actin-driven migration triggered by N-cadherin

Authors:
Giger FA, David NB
Citation:
Proc Natl Acad Sci U S A. 2017 Sep 5. pii: 201708116. doi: 10.1073/pnas.1708116114. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Germ-layer formation during gastrulation is both a fundamental step of development and a paradigm for tissue formation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Giger FA, David NB. Endodermal germ-layer formation through active actin-driven migration triggered by N-cadherin. Proc Natl Acad Sci U S A. 2017 Sep 5. pii: 201708116. doi: 10.1073/pnas.1708116114. [Epub ahead of print].

A right-handed signalling pathway drives heart looping in vertebrates

Authors:
Ocaña OH, Coskun H, Minguillón C, Murawala P, Tanaka AM, Galcerán J, Muñoz-Chápuli R, Nieto MA
Citation:
Nature. 2017;549:86-90. doi:doi:10.1038/nature23454
Epub:
Not Epub
Abstract:
Most animals show external bilateral symmetry, which hinders the observation of multiple internal left–right (L/R) asymmetries...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ocaña OH, Coskun H, Minguillón C, Murawala P, Tanaka AM, Galcerán J, Muñoz-Chápuli R, Nieto MA. A right-handed signalling pathway drives heart looping in vertebrates. Nature. 2017;549:86-90. doi:doi:10.1038/nature23454.

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