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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Placeholder nucleosomes underlie germline-to-embryo DNA methylation reprogramming

Authors:
Murphy PJ, Wu SF, James CR, Wike CL, Cairns BR
Citation:
BioRxiv. 2017;[preprint] doi:10.1101/204792
Epub:
Not Epub
Abstract:
The fate and function of epigenetic marks during the germline-to-embryo transition is a key issue in developmental biology,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Murphy PJ, Wu SF, James CR, Wike CL, Cairns BR. Placeholder nucleosomes underlie germline-to-embryo DNA methylation reprogramming. BioRxiv. 2017;[preprint] doi:10.1101/204792 .

PFKFB4 control of Akt signaling is essential for premigratory and migratory neural crest formation

Authors:
Figueiredo AL, Maczkowiak F, Borday C, Pla P, Sittewelle M, Pegoraro C, Monsoro-Burq AH
Citation:
Development. 2017 Oct 16. pii: dev.157644. doi: 10.1242/dev.157644. [Epub ahead of print]
Epub:
Yes
Abstract:
Neural crest (NC) specification comprises an early phase, initiating immature NC progenitors formation at neural plate stage,...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Figueiredo AL, Maczkowiak F, Borday C, Pla P, Sittewelle M, Pegoraro C, Monsoro-Burq AH. PFKFB4 control of Akt signaling is essential for premigratory and migratory neural crest formation. Development. 2017 Oct 16. pii: dev.157644. doi: 10.1242/dev.157644. [Epub ahead of print].

Zebrafish aversive taste co-receptor is expressed in both chemo- and mechanosensory cells and plays a role in lateral line development

Authors:
Mojib N, Xu J, Bartolek Z, Imhoff B, McCarty NA, Shin CH, Kubanek J
Citation:
Sci Rep. 2017 Oct 18;7(1):13475. doi: 10.1038/s41598-017-14042-3
Epub:
Not Epub
Abstract:
Fishes rely on both chemical and tactile senses to orient themselves to avoid predators, and to detect and taste food. This is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mojib N, Xu J, Bartolek Z, Imhoff B, McCarty NA, Shin CH, Kubanek J. Zebrafish aversive taste co-receptor is expressed in both chemo- and mechanosensory cells and plays a role in lateral line development. Sci Rep. 2017 Oct 18;7(1):13475. doi: 10.1038/s41598-017-14042-3.

CD146 is essential for PDGFRβ-induced pericyte recruitment

Authors:
Chen J, Luo Y, Huang H, Wu S, Feng J, Zhang J, Yan X
Citation:
Protein Cell. 2017. doi:10.1007/s13238-017-0484-5
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen J, Luo Y, Huang H, Wu S, Feng J, Zhang J, Yan X. CD146 is essential for PDGFRβ-induced pericyte recruitment. Protein Cell. 2017. doi:10.1007/s13238-017-0484-5.

WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome

Authors:
Kim Y-J, Osborn D, Lee J-Y, Araki M, Araki K, Mohun T, Kansakoski JEM, Brandstack N, Kim H-T, Miralles F, Kim C-H, Brown NA, Kim H-G, Martinez-Barbera JP, Ataliotis P, Raivio T, Layman LC, Kim S-H
Citation:
bioRxiv. 2017;[preprint] doi: https://doi.org/10.1101/200154
Epub:
Not Epub
Abstract:
WDR11 has been implicated in congenital hypogonadotropic hypogonadism (CHH) and Kallmann syndrome (KS), human developmental...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim Y-J, Osborn D, Lee J-Y, Araki M, Araki K, Mohun T, Kansakoski JEM, Brandstack N, Kim H-T, Miralles F, Kim C-H, Brown NA, Kim H-G, Martinez-Barbera JP, Ataliotis P, Raivio T, Layman LC, Kim S-H. WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome. bioRxiv. 2017;[preprint] doi: https://doi.org/10.1101/200154.

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover

Authors:
Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C
Citation:
Dev Cell. 2017 Oct 9;43(1):71-82.e6. doi: 10.1016/j.devcel.2017.09.011
Epub:
Not Epub
Abstract:
Angiopoietin-like 4 (ANGPTL4) is a secreted signaling protein that is implicated in cardiovascular disease, metabolic disorder...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C. Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. Dev Cell. 2017 Oct 9;43(1):71-82.e6. doi: 10.1016/j.devcel.2017.09.011.

Hey2 restricts cardiac progenitor addition to the developing heart

Authors:
Gibb N, Lazic S, Deshwar AR, Yuan X, Wilson MD, Scott IC
Citation:
bioRxiv. 2017;[preprint] doi:10.1101/199638
Epub:
Yes
Abstract:
A key event in vertebrate heart development is the timely addition of second heart field (SHF) progenitor cells to the poles of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gibb N, Lazic S, Deshwar AR, Yuan X, Wilson MD, Scott IC . Hey2 restricts cardiac progenitor addition to the developing heart. bioRxiv. 2017;[preprint] doi:10.1101/199638.

Whole Genome Sequencing-Based Mapping and Candidate Identification of Mutations from Fixed Zebrafish Tissue

Authors:
Sanchez NE, Harty BL, O'Reilly-Pol T, Ackerman SD, Herbert AL, Holmgren M, Johnson SL, Gray RS, Monk KR
Citation:
G3 (Bethesda). 2017 Oct 5;7(10):3415-3425. doi: 10.1534/g3.117.300212
Epub:
Not Epub
Abstract:
As forward genetic screens in zebrafish become more common, the number of mutants that cannot be identified by gross morphology...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sanchez NE, Harty BL, O'Reilly-Pol T, Ackerman SD, Herbert AL, Holmgren M, Johnson SL, Gray RS, Monk KR. Whole Genome Sequencing-Based Mapping and Candidate Identification of Mutations from Fixed Zebrafish Tissue. G3 (Bethesda). 2017 Oct 5;7(10):3415-3425. doi: 10.1534/g3.117.300212.

Zinc finger protein 365 is a new maternal LPS-binding protein that defends zebrafish embryos against gram-negative bacterial infections

Authors:
Du X, Zhou Y, Song L, Wang X, Zhang S
Citation:
FASEB J. 2017 Oct 17. pii: fj.201700694R. doi: 10.1096/fj.201700694R. [Epub ahead of print]
Epub:
Yes
Abstract:
Zinc finger protein 365 (ZNF365) is widespread in animals, but its function and mechanism remains poorly defined. Here we...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Du X, Zhou Y, Song L, Wang X, Zhang S. Zinc finger protein 365 is a new maternal LPS-binding protein that defends zebrafish embryos against gram-negative bacterial infections. FASEB J. 2017 Oct 17. pii: fj.201700694R. doi: 10.1096/fj.201700694R. [Epub ahead of print].

Wilms tumor protein-dependent transcription of VEGF receptor 2 and hypoxia regulate expression of the testis-promoting gene Sox9 in murine embryonic gonads

Authors:
Kirschner KM, Sciesielski LK, Krueger K, Scholz H
Citation:
J Biol Chem. 2017 Dec 8;292(49):20281-20291. doi: 10.1074/jbc.M117.816751. Epub 2017 Oct 17.
Epub:
Not Epub
Abstract:
The Wilms tumor protein 1 (WT1) has been implicated in the control of several genes in sexual development, but its function in...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
explant culture: murine gonads, kidneys
Citation Extract:
Kirschner KM, Sciesielski LK, Krueger K, Scholz H. Wilms tumor protein-dependent transcription of VEGF receptor 2 and hypoxia regulate expression of the testis-promoting gene Sox9 in murine embryonic gonads. J Biol Chem. 2017 Dec 8;292(49):20281-20291. doi: 10.1074/jbc.M117.816751. Epub 2017 Oct 17..

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