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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Mural lymphatic endothelial cells regulate meningeal angiogenesis in the zebrafish

Authors:
Bower NI, Koltowska K, Pichol-Thievend C, Virshup I, Paterson S, Lagendijk AK, Wang W, Lindsey BW, Bent SJ, Baek S, Rondon-Galeano M, Hurley DG, Mochizuki N, Simons C, Francois M, Wells CA, Kaslin J, Hogan BM
Citation:
Nat Neurosci. 2017 May 1. doi: 10.1038/nn.4558. [Epub ahead of print]
Epub:
Yes
Abstract:
Mural cells of the vertebrate brain maintain vascular integrity and function, play roles in stroke and are involved in...
Link:
http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.4558.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bower NI, Koltowska K, Pichol-Thievend C, Virshup I, Paterson S, Lagendijk AK, Wang W, Lindsey BW, Bent SJ, Baek S, Rondon-Galeano M, Hurley DG, Mochizuki N, Simons C, Francois M, Wells CA, Kaslin J, Hogan BM. Mural lymphatic endothelial cells regulate meningeal angiogenesis in the zebrafish. Nat Neurosci. 2017 May 1. doi: 10.1038/nn.4558. [Epub ahead of print].

USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling

Authors:
Zhou F, Xie F, Jin K, Zhang Z, Clerici M, Gao R, van Dinther M, Sixma TK, Huang H, Zhang L, ten Dijke P
Citation:
EMBO J. 2017;[Epub ahead of print] doi:10.15252/embj.201695372
Epub:
Yes
Abstract:
SMAD4 is a common intracellular effector for TGF-β family cytokines, but the mechanism by which its activity is dynamically...
Link:
http://onlinelibrary.wiley.com/wol1/doi/10.15252/embj.201695372/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou F, Xie F, Jin K, Zhang Z, Clerici M, Gao R, van Dinther M, Sixma TK, Huang H, Zhang L, ten Dijke P. USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling. EMBO J. 2017;[Epub ahead of print] doi:10.15252/embj.201695372.

The Role of Oxytocin Neurons in the Bed Nucleus of the Stria Terminalis in Mediating Social Withdrawal

Authors:
Duque-Wilckens N, Steinman M, Grinevich V, Trainor B
Citation:
Biol Psychiat. 2017;81(10)suppl:S44-S45
Epub:
Not Epub
Abstract:
See link
Link:
http://www.biologicalpsychiatryjournal.com/article/S0006-3223(17)30238-X/abstract
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Duque-Wilckens N, Steinman M, Grinevich V, Trainor B. The Role of Oxytocin Neurons in the Bed Nucleus of the Stria Terminalis in Mediating Social Withdrawal. Biol Psychiat. 2017;81(10)suppl:S44-S45.

Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense

Authors:
Wiemann P, Perevitsky A, Lim FY, Shadkchan Y, Knox BP, Landero Figueora JA, Choera T, Niu M, Steinberger AJ, Wüthrich M, Idol RA, Klein BS, Dinauer MC, Huttenlocher A, Osherov N, Keller NP
Citation:
Cell Rep. 2017 May 2;19(5):1008-1021. doi: 10.1016/j.celrep.2017.04.019
Epub:
Not Epub
Abstract:
The Fenton-chemistry-generating properties of copper ions are considered a potent phagolysosome defense against pathogenic...
Link:
http://www.cell.com/cell-reports/abstract/S2211-1247(17)30494-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wiemann P, Perevitsky A, Lim FY, Shadkchan Y, Knox BP, Landero Figueora JA, Choera T, Niu M, Steinberger AJ, Wüthrich M, Idol RA, Klein BS, Dinauer MC, Huttenlocher A, Osherov N, Keller NP. Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense. Cell Rep. 2017 May 2;19(5):1008-1021. doi: 10.1016/j.celrep.2017.04.019.

Importance of deubiquitinases in zebrafish craniofacial development

Authors:
Tse WKF
Citation:
Biochem Biophys Res Commun. 2017 Apr 24. pii: S0006-291X(17)30814-8. doi: 10.1016/j.bbrc.2017.04.132. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Deconjugation of ubiquitin and/or ubiqutin-like modified substrates is essential to maintain a sufficient free ubiquitin within...
Link:
http://www.sciencedirect.com/science/article/pii/S0006291X17308148
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tse WKF. Importance of deubiquitinases in zebrafish craniofacial development. Biochem Biophys Res Commun. 2017 Apr 24. pii: S0006-291X(17)30814-8. doi: 10.1016/j.bbrc.2017.04.132. [Epub ahead of print].

Brorin is required for neurogenesis, gliogenesis, and commissural axon guidance in the zebrafish forebrain

Authors:
Miyake A, Mekata Y, Fujibayashi H, Nakanishi K, Konishi M, Itoh N
Citation:
PLoS One. 2017 Apr 27;12(4):e0176036. doi: 10.1371/journal.pone.0176036. eCollection 2017
Epub:
Not Epub
Abstract:
Bmps regulate numerous neural functions with their regulators. We previously identified Brorin, a neural-specific secreted...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176036
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miyake A, Mekata Y, Fujibayashi H, Nakanishi K, Konishi M, Itoh N. Brorin is required for neurogenesis, gliogenesis, and commissural axon guidance in the zebrafish forebrain. PLoS One. 2017 Apr 27;12(4):e0176036. doi: 10.1371/journal.pone.0176036. eCollection 2017.

Role of CC Cytokines in Spatial Arrangement of the Inner Cell Mass of the Bovine Embryo

Authors:
Negrón-Pérez VM, Vargas-Franco D, Hansen PJ
Citation:
Biol Reprod. 2017 Apr 25. doi: 10.1093/biolre/iox037. [Epub ahead of print]
Epub:
Yes
Abstract:
The process of spatial rearrangement of cells of the inner cell mass (ICM) that are destined to become hypoblast is not well...
Link:
https://academic.oup.com/biolreprod/article-abstract/doi/10.1093/biolre/iox037/3752503/Role-of-CC-Cytokines-in-Spatial-Arrangement-of-the
Delivery Method:
microinjection
Organism or Cell Type:
Bos taurus (cattle)
Citation Extract:
Negrón-Pérez VM, Vargas-Franco D, Hansen PJ. Role of CC Cytokines in Spatial Arrangement of the Inner Cell Mass of the Bovine Embryo. Biol Reprod. 2017 Apr 25. doi: 10.1093/biolre/iox037. [Epub ahead of print].

Characterization and expression analysis of Galnts in developing Strongylocentrotus purpuratus embryos

Authors:
Famiglietti AL, Wei Z, Beres TM, Milac AL, Tran DT, Patel D, Angerer RC, Angerer LM, Tabak LA
Citation:
PLoS One. 2017 Apr 27;12(4):e0176479. doi: 10.1371/journal.pone.0176479. eCollection 2017
Epub:
Not Epub
Abstract:
Mucin-type O-glycosylation is a ubiquitous posttranslational modification in which N-Acetylgalactosamine (GalNAc) is added to...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176479
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Famiglietti AL, Wei Z, Beres TM, Milac AL, Tran DT, Patel D, Angerer RC, Angerer LM, Tabak LA. Characterization and expression analysis of Galnts in developing Strongylocentrotus purpuratus embryos. PLoS One. 2017 Apr 27;12(4):e0176479. doi: 10.1371/journal.pone.0176479. eCollection 2017.

CLPB mutations cause 3-methylglutaconic aciduria, progressive brain atrophy, intellectual disability, congenital neutropenia, cataracts, movement disorder

Authors:
Wortmann SB, Ziętkiewicz S, Kousi M, Szklarczyk R, Haack TB, Gersting SW, Muntau AC, Rakovic A, Renkema GH, Rodenburg RJ, Strom TM, Meitinger T, Rubio-Gozalbo ME, Chrusciel E, Distelmaier F, Golzio C, Jansen JH, van Karnebeek C, Lillquist Y, Lücke T, Õunap K, Zordania R, Yaplito-Lee J, van Bokhoven H, Spelbrink JN, Vaz FM, Pras-Raves M, Ploski R, Pronicka E, Klein C, Willemsen MA, de Brouwer AP, Prokisch H, Katsanis N, Wevers RA.
Citation:
Am J Hum Genet. 2015 Feb 5;96(2):245-57. doi: 10.1016/j.ajhg.2014.12.013. Epub 2015 Jan 15
Epub:
Not Epub
Abstract:
We studied a group of individuals with elevated urinary excretion of 3-methylglutaconic acid, neutropenia that can develop into...
Link:
http://www.cell.com/ajhg/fulltext/S0002-9297(14)00519-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wortmann SB, Ziętkiewicz S, Kousi M, Szklarczyk R, Haack TB, Gersting SW, Muntau AC, Rakovic A, Renkema GH, Rodenburg RJ, Strom TM, Meitinger T, Rubio-Gozalbo ME, Chrusciel E, Distelmaier F, Golzio C, Jansen JH, van Karnebeek C, Lillquist Y, Lücke T, Õunap K, Zordania R, Yaplito-Lee J, van Bokhoven H, Spelbrink JN, Vaz FM, Pras-Raves M, Ploski R, Pronicka E, Klein C, Willemsen MA, de Brouwer AP, Prokisch H, Katsanis N, Wevers RA.. CLPB mutations cause 3-methylglutaconic aciduria, progressive brain atrophy, intellectual disability, congenital neutropenia, cataracts, movement disorder. Am J Hum Genet. 2015 Feb 5;96(2):245-57. doi: 10.1016/j.ajhg.2014.12.013. Epub 2015 Jan 15.

Identification of target genes downstream of Semaphorin6A/PlexinA2 signaling in zebrafish

Authors:
Emerson SE, St Clair RM, Waldron AL, Bruno SR, Duong A, Driscoll HE, Ballif BA, McFarlane S, Ebert AM
Citation:
Dev Dyn. 2017 Apr 25. doi: 10.1002/dvdy.24512. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Semaphorin (Sema)/Plexin (Plxn) signaling is important for many aspects of neuronal development, however the...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dvdy.24512/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Emerson SE, St Clair RM, Waldron AL, Bruno SR, Duong A, Driscoll HE, Ballif BA, McFarlane S, Ebert AM. Identification of target genes downstream of Semaphorin6A/PlexinA2 signaling in zebrafish. Dev Dyn. 2017 Apr 25. doi: 10.1002/dvdy.24512. [Epub ahead of print].

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