You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Transcriptomics reveal an integrative role for maternal thyroid hormones during zebrafish embryogenesis

Authors:
Silva N, Louro B, Trindade M, Power DM, Campinho MA
Citation:
Sci Rep. 2017;7:16657. doi:10.1038/s41598-017-16951-9
Epub:
Not Epub
Abstract:
Thyroid hormones (THs) are essential for embryonic brain development but the genetic mechanisms involved in the action of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Silva N, Louro B, Trindade M, Power DM, Campinho MA. Transcriptomics reveal an integrative role for maternal thyroid hormones during zebrafish embryogenesis. Sci Rep. 2017;7:16657. doi:10.1038/s41598-017-16951-9.

Inhibition of Delta-induced Notch signaling using fucose analogs

Authors:
Schneider M, Kumar V, Nordstrøm LU, Feng L, Takeuchi H, Hao H, Luca VC, Garcia KC, Stanley P, Wu P, Haltiwanger RS
Citation:
Nat Chem Biol. 2017 Nov 27. doi: 10.1038/nchembio.2520. [Epub ahead of print]
Epub:
Yes
Abstract:
Notch is a cell-surface receptor that controls cell-fate decisions and is regulated by O-glycans attached to epidermal growth...
Organism or Cell Type:
zebrafish
Citation Extract:
Schneider M, Kumar V, Nordstrøm LU, Feng L, Takeuchi H, Hao H, Luca VC, Garcia KC, Stanley P, Wu P, Haltiwanger RS. Inhibition of Delta-induced Notch signaling using fucose analogs. Nat Chem Biol. 2017 Nov 27. doi: 10.1038/nchembio.2520. [Epub ahead of print].

Accurate quantification of homologous recombination in zebrafish: brca2 deficiency as a paradigm

Authors:
Vierstraete J, Willaert A, Vermassen P, Coucke PJ, Vral A, Claes KBM
Citation:
Sci Rep. 2017;7:16518. doi:10.1038/s41598-017-16725-3
Epub:
Not Epub
Abstract:
Homologous Recombination (HR) repair is essential for repairing DNA double strand breaks (DSB) in dividing cells and preventing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vierstraete J, Willaert A, Vermassen P, Coucke PJ, Vral A, Claes KBM. Accurate quantification of homologous recombination in zebrafish: brca2 deficiency as a paradigm. Sci Rep. 2017;7:16518. doi:10.1038/s41598-017-16725-3.

Role of WNT10A in failure of tooth development in humans and zebrafish

Authors:
Yuan Q, Zhao M, Tandon B, Maili L, Liu X, Zhang A, Baugh EH, Tran T, Silva RM, Hecht JT, Swindell EC, Wagner DS, Letra A
Citation:
Mol Genet Genomic Med. 2017 Nov;5(6):730-741. doi: 10.1002/mgg3.332. Epub 2017 Sep 14
Epub:
Not Epub
Abstract:
BACKGROUND: Oligodontia is a severe form of tooth agenesis characterized by the absence of six or more permanent teeth....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yuan Q, Zhao M, Tandon B, Maili L, Liu X, Zhang A, Baugh EH, Tran T, Silva RM, Hecht JT, Swindell EC, Wagner DS, Letra A. Role of WNT10A in failure of tooth development in humans and zebrafish. Mol Genet Genomic Med. 2017 Nov;5(6):730-741. doi: 10.1002/mgg3.332. Epub 2017 Sep 14.

Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development

Authors:
Ghosh TK, Aparicio-Sánchez JJ, Buxton S, Ketley A, Mohamed T, Rutland CS, Loughna S, Brook JD
Citation:
J Mol Cell Cardiol. 2017 Nov 22. pii: S0022-2828(17)30348-6. doi: 10.1016/j.yjmcc.2017.11.013. [Epub ahead of print]
Epub:
Yes
Abstract:
TBX5 plays a critical role in heart and forelimb development. Mutations in TBX5 cause Holt-Oram syndrome, an autosomal dominant...
Organism or Cell Type:
zebrafish
Citation Extract:
Ghosh TK, Aparicio-Sánchez JJ, Buxton S, Ketley A, Mohamed T, Rutland CS, Loughna S, Brook JD. Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development. J Mol Cell Cardiol. 2017 Nov 22. pii: S0022-2828(17)30348-6. doi: 10.1016/j.yjmcc.2017.11.013. [Epub ahead of print].

Protein localization screening in vivo reveals novel regulators of multiciliated cell development and function

Authors:
Fan Tu, Jakub Sedzinski, Yun Ma, Edward M. Marcotte, John B. Wallingford
Citation:
J Cell Sci. 2017;[Epub ahead of print] doi:10.1242/jcs.206565
Epub:
Yes
Abstract:
Multiciliated cells (MCCs) drive fluid flow in diverse tubular organs and are essential for the development and homeostasis of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Fan Tu, Jakub Sedzinski, Yun Ma, Edward M. Marcotte, John B. Wallingford. Protein localization screening in vivo reveals novel regulators of multiciliated cell development and function. J Cell Sci. 2017;[Epub ahead of print] doi:10.1242/jcs.206565.

Evolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes

Authors:
Burguera D, Marquez Y, Racioppi C, Permanyer J, Torres-Méndez A, Esposito R, Albuixech-Crespo B, Fanlo L, D’Agostino Y, Gohr A, Navas-Perez E, Riesgo A, Cuomo C, Benvenuto G, Christiaen LA, Martí E, D’Aniello S, Spagnuolo A, Ristoratore F, Arnone MI, Garcia-Fernàndez J, Irimia M
Citation:
Nat Comm. 2017;8:1799. doi:10.1038/s41467-017-01961-y
Epub:
Not Epub
Abstract:
Epithelial-mesenchymal interactions are crucial for the development of numerous animal structures. Thus, unraveling how...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Burguera D, Marquez Y, Racioppi C, Permanyer J, Torres-Méndez A, Esposito R, Albuixech-Crespo B, Fanlo L, D’Agostino Y, Gohr A, Navas-Perez E, Riesgo A, Cuomo C, Benvenuto G, Christiaen LA, Martí E, D’Aniello S, Spagnuolo A, Ristoratore F, Arnone MI, Garcia-Fernàndez J, Irimia M. Evolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes. Nat Comm. 2017;8:1799. doi:10.1038/s41467-017-01961-y.

The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells

Authors:
Adamo P, Porazinski S, Rajatileka S, Jumbe S, Hagen R, Cheung MK, Wilson I, Ladomery MR
Citation:
Oncol Lett. 2017 Nov;14(5):5605-5610. doi: 10.3892/ol.2017.6841. Epub 2017 Aug 28
Epub:
Not Epub
Abstract:
The oncogene ETS-related gene (ERG) encodes a transcription factor with roles in the regulation of haematopoiesis, angiogenesis...
Delivery Method:
Vivo-Morpholino + Endo-Porter
Organism or Cell Type:
cell culture: VCaP (ATCC CRL-2876)
Citation Extract:
Adamo P, Porazinski S, Rajatileka S, Jumbe S, Hagen R, Cheung MK, Wilson I, Ladomery MR. The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells. Oncol Lett. 2017 Nov;14(5):5605-5610. doi: 10.3892/ol.2017.6841. Epub 2017 Aug 28.

MYC targeted long non-coding RNA DANCR promotes cancer in part by reducing p21 levels

Authors:
Lu Y, Hu Z, Mangala LS, Stine ZE, Hu X, Jiang D, Xiang Y, Zhang Y, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Demarzo A, Sood AK, Zhang L, Dang CV
Citation:
Cancer Res. 2017;[Epub ahead of print] doi:10.1158/0008-5472
Epub:
Yes
Abstract:
The MYC oncogene broadly promotes transcription mediated by all nuclear RNA polymerases, thereby acting as a positive modifier...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: P493-6
Citation Extract:
Lu Y, Hu Z, Mangala LS, Stine ZE, Hu X, Jiang D, Xiang Y, Zhang Y, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Demarzo A, Sood AK, Zhang L, Dang CV. MYC targeted long non-coding RNA DANCR promotes cancer in part by reducing p21 levels. Cancer Res. 2017;[Epub ahead of print] doi:10.1158/0008-5472.

Identification of Isthmin 1 as a Novel Clefting and Craniofacial Patterning Gene in Humans

Authors:
Lansdon LA, Darbro BW, Petrin AL, Hulstrand AM, Standley JM, Brouillette RB, Long A, Mansilla MA, Cornell RA, Murray JC, Houston DW, Manak R
Citation:
Genetics. 2017;[Epub ahead of print] doi:10.1534/genetics.117.300535
Epub:
Yes
Abstract:
Orofacial clefts are one of the most common birth defects, affecting 1-2 per 1000 births, and have a complex etiology. High-...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lansdon LA, Darbro BW, Petrin AL, Hulstrand AM, Standley JM, Brouillette RB, Long A, Mansilla MA, Cornell RA, Murray JC, Houston DW, Manak R. Identification of Isthmin 1 as a Novel Clefting and Craniofacial Patterning Gene in Humans. Genetics. 2017;[Epub ahead of print] doi:10.1534/genetics.117.300535.

Pages