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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development

Authors:
Kroeger PT Jr, Drummond BE, Miceli R, McKernan M, Gerlach GF, Marra AN, Fox A, McCampbell KK, Leshchiner I, Rodriguez-Mari A, BreMiller R, Thummel R, Davidson AJ, Postlethwait J, Goessling W, Wingert RA
Citation:
Dev Biol. 2017 Jun 1. pii: S0012-1606(16)30468-7. doi: 10.1016/j.ydbio.2017.05.025. [Epub ahead of print]
Epub:
Yes
Abstract:
The zebrafish kidney is conserved with other vertebrates, making it an excellent genetic model to study renal development. The...
Organism or Cell Type:
zebrafish
Citation Extract:
Kroeger PT Jr, Drummond BE, Miceli R, McKernan M, Gerlach GF, Marra AN, Fox A, McCampbell KK, Leshchiner I, Rodriguez-Mari A, BreMiller R, Thummel R, Davidson AJ, Postlethwait J, Goessling W, Wingert RA. The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development. Dev Biol. 2017 Jun 1. pii: S0012-1606(16)30468-7. doi: 10.1016/j.ydbio.2017.05.025. [Epub ahead of print].

Sox2 regulates Müller glia reprogramming and proliferation in the regenerating zebrafish retina via Lin28 and Ascl1a

Authors:
Gorsuch RA, Lahne M, Yarka CE, Petravick ME, Li J, Hyde DR
Citation:
Exp Eye Res. 2017 May 31. pii: S0014-4835(16)30265-2. doi: 10.1016/j.exer.2017.05.012. [Epub ahead of print]
Epub:
Yes
Abstract:
Sox2 is a well-established neuronal stem cell-associated transcription factor that regulates neural development and adult...
Organism or Cell Type:
zebrafish
Citation Extract:
Gorsuch RA, Lahne M, Yarka CE, Petravick ME, Li J, Hyde DR. Sox2 regulates Müller glia reprogramming and proliferation in the regenerating zebrafish retina via Lin28 and Ascl1a. Exp Eye Res. 2017 May 31. pii: S0014-4835(16)30265-2. doi: 10.1016/j.exer.2017.05.012. [Epub ahead of print].

Complement component C3aR constitutes a novel regulator for chick eye morphogenesis

Authors:
Grajales-Esquivel E, Luz-Madrigal A, Bierly J, Haynes T, Reis ES, Han Z, Gutierrez C, McKinney Z, Tzekou A, Lambris JD, Tsonis PA, Del Rio-Tsonis K
Citation:
Dev Biol. 2017 May 30. pii: S0012-1606(15)30062-2. doi: 10.1016/j.ydbio.2017.05.019. [Epub ahead of print]
Epub:
Yes
Abstract:
Complement components have been implicated in a wide variety of functions including neurogenesis, proliferation, cell migration...
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Grajales-Esquivel E, Luz-Madrigal A, Bierly J, Haynes T, Reis ES, Han Z, Gutierrez C, McKinney Z, Tzekou A, Lambris JD, Tsonis PA, Del Rio-Tsonis K. Complement component C3aR constitutes a novel regulator for chick eye morphogenesis. Dev Biol. 2017 May 30. pii: S0012-1606(15)30062-2. doi: 10.1016/j.ydbio.2017.05.019. [Epub ahead of print].

Boron Nitride Nanotubes for Gene Silencing

Authors:
Şen Ö, Çobandede Z, Emanet M, Bayrak ÖF, Çulha M
Citation:
Biochim Biophys Acta. 2017 May 29. pii: S0304-4165(17)30178-2. doi: 10.1016/j.bbagen.2017.05.026. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Non-viral gene delivery is increasingly investigated as an alternative to viral vectors due to low toxicity and...
Delivery Method:
nanotubes
Organism or Cell Type:
cell culture: MDA-MB-231-luc2
Citation Extract:
Şen Ö, Çobandede Z, Emanet M, Bayrak ÖF, Çulha M. Boron Nitride Nanotubes for Gene Silencing. Biochim Biophys Acta. 2017 May 29. pii: S0304-4165(17)30178-2. doi: 10.1016/j.bbagen.2017.05.026. [Epub ahead of print].

Substrate properties of zebrafish Rtn4b/Nogo and axon regeneration in the zebrafish optic nerve

Authors:
Bodrikov V, Welte C, Wiechers M, Weschenfelder M, Kaur G, Shypitsyna A, Pinzon-Olejua A, Bastmeyer M, Stuermer CAO
Citation:
J Comp Neurol. 2017 May 30. doi: 10.1002/cne.24253. [Epub ahead of print]
Epub:
Yes
Abstract:
This study explored why lesioned retinal ganglion cell (RGC) axons regenerate successfully in the zebrafish optic nerve despite...
Organism or Cell Type:
zebrafish
Citation Extract:
Bodrikov V, Welte C, Wiechers M, Weschenfelder M, Kaur G, Shypitsyna A, Pinzon-Olejua A, Bastmeyer M, Stuermer CAO. Substrate properties of zebrafish Rtn4b/Nogo and axon regeneration in the zebrafish optic nerve. J Comp Neurol. 2017 May 30. doi: 10.1002/cne.24253. [Epub ahead of print].

Gβ1 is required for neutrophil migration in zebrafish

Authors:
Ke W, Ye D, Mersch K, Xu H, Chen S, Lin F
Citation:
Dev Biol. 2017 May 26. pii: S0012-1606(16)30813-2. doi: 10.1016/j.ydbio.2017.05.024. [Epub ahead of print]
Epub:
Yes
Abstract:
Signaling mediated by G protein-coupled receptors (GPCRs) is essential for the migration of cells toward chemoattractants. The...
Organism or Cell Type:
zebrafish
Citation Extract:
Ke W, Ye D, Mersch K, Xu H, Chen S, Lin F. Gβ1 is required for neutrophil migration in zebrafish. Dev Biol. 2017 May 26. pii: S0012-1606(16)30813-2. doi: 10.1016/j.ydbio.2017.05.024. [Epub ahead of print].

Erythropoietin signaling regulates heme biosynthesis.

Authors:
Chung J, Wittig JG, Ghamari A, Maeda M, Dailey TA, Bergonia H, Kafina MD, Coughlin EE, Minogue CE, Hebert AS, Li L, Kaplan J, Lodish HF, Bauer DE, Orkin SH, Cantor AB, Maeda T, Phillips JD, Coon JJ, Pagliarini DJ, Dailey HA, Paw BH
Citation:
eLife. 2017;[accepted manuscript] doi:10.7554/eLife.24767
Epub:
Not Epub
Abstract:
Heme is required for survival of all cells, and in most eukaryotes, is produced through a series of eight enzymatic reactions....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chung J, Wittig JG, Ghamari A, Maeda M, Dailey TA, Bergonia H, Kafina MD, Coughlin EE, Minogue CE, Hebert AS, Li L, Kaplan J, Lodish HF, Bauer DE, Orkin SH, Cantor AB, Maeda T, Phillips JD, Coon JJ, Pagliarini DJ, Dailey HA, Paw BH. Erythropoietin signaling regulates heme biosynthesis.. eLife. 2017;[accepted manuscript] doi:10.7554/eLife.24767.

Mutual Regulation of NOD2 and RIG-I in Zebrafish Provides Insights into the Coordination between Innate Antibacterial and Antiviral Signaling Pathways

Authors:
Nie L, Xu X-X, Xiang L-X, Shao J-Z, Chen J
Citation:
Int J Molec Sci. 2017;18(6):1147. doi:10.3390/ijms18061147
Epub:
Not Epub
Abstract:
Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) and retinoic acid-inducible gene I (RIG-I) are two...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nie L, Xu X-X, Xiang L-X, Shao J-Z, Chen J. Mutual Regulation of NOD2 and RIG-I in Zebrafish Provides Insights into the Coordination between Innate Antibacterial and Antiviral Signaling Pathways. Int J Molec Sci. 2017;18(6):1147. doi:10.3390/ijms18061147.

Targeted Delivery of FLT-Morpholino Using Cyclic RGD Peptide

Authors:
Uehara H, Muddana SK, Zhang X, Das SK, Bhuvanagiri S, Liu J, Wu Y, Choi S, Carroll LS, Archer B, Ambati BK
Citation:
Transl Vis Sci Technol. 2017 May 24;6(3):9. doi: 10.1167/tvst.6.3.9. eCollection 2017 May
Epub:
Not Epub
Abstract:
PURPOSE: We previously showed that intravitreal injection of the sFLT morpholino-oligomer (FLT-MO) suppresses laser-induced...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: primary mouse aortic endothelial cells (MAECs), mice
Citation Extract:
Uehara H, Muddana SK, Zhang X, Das SK, Bhuvanagiri S, Liu J, Wu Y, Choi S, Carroll LS, Archer B, Ambati BK. Targeted Delivery of FLT-Morpholino Using Cyclic RGD Peptide. Transl Vis Sci Technol. 2017 May 24;6(3):9. doi: 10.1167/tvst.6.3.9. eCollection 2017 May.

Knockdown of epigenetic transcriptional co-regulator Brd2a disrupts apoptosis and proper formation of hindbrain and midbrain-hindbrain boundary (MHB) region in zebrafish

Authors:
Murphy T, Melville H, Fradkin E, Bistany G, Branigan G, Olsen K, Comstock CR, Hanby H, Garbade E, DiBenedetto AJ
Citation:
Mech Dev. 2017 May 23. pii: S0925-4773(16)30065-X. doi: 10.1016/j.mod.2017.05.003. [Epub ahead of print]
Epub:
Yes
Abstract:
Brd2 is a member of the bromodomain-extraterminal domain (BET) family of proteins and functions as an acetyl-histone-directed...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Murphy T, Melville H, Fradkin E, Bistany G, Branigan G, Olsen K, Comstock CR, Hanby H, Garbade E, DiBenedetto AJ. Knockdown of epigenetic transcriptional co-regulator Brd2a disrupts apoptosis and proper formation of hindbrain and midbrain-hindbrain boundary (MHB) region in zebrafish. Mech Dev. 2017 May 23. pii: S0925-4773(16)30065-X. doi: 10.1016/j.mod.2017.05.003. [Epub ahead of print].

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