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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Contrasting the Role of xCT and GLT-1 Upregulation in the Ability of Ceftriaxone to Attenuate the Cue-Induced Reinstatement of Cocaine Seeking and Normalize AMPA Receptor Subunit Expression

Authors:
LaCrosse AL, O'Donovan SM, Sepulveda-Orengo MT, McCullumsmith RE, Reissner KJ, Schwendt M, Knackstedt LA
Citation:
J Neurosci. 2017 Jun 14;37(24):5809-5821. doi: 10.1523/JNEUROSCI.3717-16.2017. Epub 2017 May 11
Epub:
Not Epub
Abstract:
Long-term treatment with ceftriaxone attenuates the reinstatement of cocaine seeking while increasing the function of the...
Link:
http://www.jneurosci.org/content/37/24/5809
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
rat
Citation Extract:
LaCrosse AL, O'Donovan SM, Sepulveda-Orengo MT, McCullumsmith RE, Reissner KJ, Schwendt M, Knackstedt LA. Contrasting the Role of xCT and GLT-1 Upregulation in the Ability of Ceftriaxone to Attenuate the Cue-Induced Reinstatement of Cocaine Seeking and Normalize AMPA Receptor Subunit Expression. J Neurosci. 2017 Jun 14;37(24):5809-5821. doi: 10.1523/JNEUROSCI.3717-16.2017. Epub 2017 May 11.

Electrostatic Cycling of Hybridization Using Nonionic DNA Mimics

Authors:
Ruffin S, Hung IA, Koniges UM, Levicky R
Citation:
ACS Sens. 2017 Jul 28;2(7):892-896. doi: 10.1021/acssensors.7b00100. Epub 2017 Jun 20.
Epub:
Not Epub
Abstract:
This study demonstrates efficient electrostatic control of surface hybridization through use of morpholinos, a charge-neutral...
Link:
http://pubs.acs.org/doi/abs/10.1021/acssensors.7b00100?journalCode=ascefj
Citation Extract:
Ruffin S, Hung IA, Koniges UM, Levicky R. Electrostatic Cycling of Hybridization Using Nonionic DNA Mimics. ACS Sens. 2017 Jul 28;2(7):892-896. doi: 10.1021/acssensors.7b00100. Epub 2017 Jun 20..

Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos

Authors:
Wu Y, Lou QY, Ge F, Xiong Q
Citation:
Sci Rep. 2017 Jun 22;7(1):4022. doi: 10.1038/s41598-017-04166-x
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are noncoding RNAs which control gene expression by the suppression of translation or the degradation of...
Link:
https://www.nature.com/articles/s41598-017-04166-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu Y, Lou QY, Ge F, Xiong Q. Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos. Sci Rep. 2017 Jun 22;7(1):4022. doi: 10.1038/s41598-017-04166-x.

A homozygous founder mutation in TRAPPC6B associates with a neurodevelopmental disorder characterised by microcephaly, epilepsy and autistic features

Authors:
Marin-Valencia I, Novarino G, Johansen A, Rosti B, Issa MY, Musaev D, Bhat G, Scott E, Silhavy JL, Stanley V, Rosti RO, Gleeson JW, Imam FB, Zaki MS, Gleeson JG
Citation:
J Med Genet. 2017 Jun 16. pii: jmedgenet-2017-104627. doi: 10.1136/jmedgenet-2017-104627. [Epub ahead of print]
Epub:
Yes
Abstract:
Background: Transport protein particle (TRAPP) is a multisubunit complex that regulates membrane trafficking through the Golgi...
Link:
http://jmg.bmj.com/content/early/2017/06/16/jmedgenet-2017-104627.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marin-Valencia I, Novarino G, Johansen A, Rosti B, Issa MY, Musaev D, Bhat G, Scott E, Silhavy JL, Stanley V, Rosti RO, Gleeson JW, Imam FB, Zaki MS, Gleeson JG. A homozygous founder mutation in TRAPPC6B associates with a neurodevelopmental disorder characterised by microcephaly, epilepsy and autistic features. J Med Genet. 2017 Jun 16. pii: jmedgenet-2017-104627. doi: 10.1136/jmedgenet-2017-104627. [Epub ahead of print].

miR-27 regulates chondrogenesis by suppressing focal adhesion kinase during pharyngeal arch development

Authors:
Kara N, Wei C, Commanday AC, Patton JG
Citation:
Dev Biol. 2017 Jun 16. pii: S0012-1606(16)30850-8. doi: 10.1016/j.ydbio.2017.06.013. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cranial neural crest cells are a multipotent cell population that generate all the elements of the pharyngeal cartilage with...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616308508
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kara N, Wei C, Commanday AC, Patton JG. miR-27 regulates chondrogenesis by suppressing focal adhesion kinase during pharyngeal arch development. Dev Biol. 2017 Jun 16. pii: S0012-1606(16)30850-8. doi: 10.1016/j.ydbio.2017.06.013. [Epub ahead of print].

The Short-Stature Homeobox-Containing Gene (shox/SHOX) Is Required for the Regulation of Cell Proliferation and Bone Differentiation in Zebrafish Embryo and Human Mesenchymal Stem Cells

Authors:
Yokokura T, Kamei H, Shibano T, Yamanaka D, Sawada-Yamaguchi R, Hakuno F, Takahashi SI, Shimizu T
Citation:
Front Endocrinol (Lausanne). 2017 Jun 8;8:125. doi: 10.3389/fendo.2017.00125. eCollection 2017
Epub:
Not Epub
Abstract:
The short-stature homeobox-containing gene (SHOX) was originally discovered as one of genes responsible for idiopathic short-...
Link:
http://journal.frontiersin.org/article/10.3389/fendo.2017.00125/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yokokura T, Kamei H, Shibano T, Yamanaka D, Sawada-Yamaguchi R, Hakuno F, Takahashi SI, Shimizu T. The Short-Stature Homeobox-Containing Gene (shox/SHOX) Is Required for the Regulation of Cell Proliferation and Bone Differentiation in Zebrafish Embryo and Human Mesenchymal Stem Cells. Front Endocrinol (Lausanne). 2017 Jun 8;8:125. doi: 10.3389/fendo.2017.00125. eCollection 2017.

Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer's disease

Authors:
Newman M, Halter L, Lim A, Lardelli M
Citation:
PLoS One. 2017 Jun 21;12(6):e0179859. doi: 10.1371/journal.pone.0179859. eCollection 2017
Epub:
Not Epub
Abstract:
Mutations in the human genes PRESENILIN1 (PSEN1), PRESENILIN2 (PSEN2) and AMYLOID BETA A4 PRECURSOR PROTEIN (APP) have been...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179859
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Newman M, Halter L, Lim A, Lardelli M. Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer's disease. PLoS One. 2017 Jun 21;12(6):e0179859. doi: 10.1371/journal.pone.0179859. eCollection 2017.

Polyquaternium-mediated delivery of morpholino oligonucleotides for exon-skipping in vitro and in mdx mice

Authors:
Wang M, Wu B, Shah SN, Lu P, Lu Q
Citation:
Drug Deliv. 2017 Nov;24(1):952-961. doi: 10.1080/10717544.2017.1337827
Epub:
Not Epub
Abstract:
Antisense oligonucleotide therapy for Duchenne muscular dystrophy has shown great potential in preclinical and clinical trials...
Link:
http://www.tandfonline.com/doi/full/10.1080/10717544.2017.1337827
Delivery Method:
polyquaternium
Organism or Cell Type:
cell culture, mouse
Citation Extract:
Wang M, Wu B, Shah SN, Lu P, Lu Q. Polyquaternium-mediated delivery of morpholino oligonucleotides for exon-skipping in vitro and in mdx mice. Drug Deliv. 2017 Nov;24(1):952-961. doi: 10.1080/10717544.2017.1337827.

An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos

Authors:
Lee WJ, Chatterjee S, Yap SP, Lim SL, Xing X, Kraus P, Sun W, Hu X, Sivakamasundari V, Chan HY, Kolatkar PR, Prabhakar S, Lufkin T
Citation:
Biomed Res Int. 2017;2017:8932583. doi: 10.1155/2017/8932583. Epub 2017 May 28
Epub:
Not Epub
Abstract:
Embryogenesis is an intricate process involving multiple genes and pathways. Some of the key transcription factors controlling...
Link:
https://www.hindawi.com/journals/bmri/2017/8932583/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee WJ, Chatterjee S, Yap SP, Lim SL, Xing X, Kraus P, Sun W, Hu X, Sivakamasundari V, Chan HY, Kolatkar PR, Prabhakar S, Lufkin T. An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos. Biomed Res Int. 2017;2017:8932583. doi: 10.1155/2017/8932583. Epub 2017 May 28.

Irf8 regulates the progression of myeloproliferative neoplasm (MPN)-like syndrome via Mertk signaling in zebrafish

Authors:
Zhao F, Shi Y, Huang Y, Zhan Y, Zhou L, Li Y, Wan Y, Li H, Huang H, Ruan H, Luo L, Li L
Citation:
Leukemia. 2017 Jun 19. doi: 10.1038/leu.2017.189. [Epub ahead of print]
Epub:
Yes
Abstract:
Interferon regulatory factor (IRF)-8 is a critical transcription factor involved in the pathogenesis of myeloid neoplasia....
Link:
https://www.nature.com/leu/journal/vaop/naam/abs/leu2017189a.html
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao F, Shi Y, Huang Y, Zhan Y, Zhou L, Li Y, Wan Y, Li H, Huang H, Ruan H, Luo L, Li L. Irf8 regulates the progression of myeloproliferative neoplasm (MPN)-like syndrome via Mertk signaling in zebrafish. Leukemia. 2017 Jun 19. doi: 10.1038/leu.2017.189. [Epub ahead of print].

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