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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Dynamics of in vivo ASC speck formation

Authors:
Kuri P, Schieber NL, Thumberger T, Wittbrodt J, Schwab Y, Leptin M
Citation:
J Cell Bio. 2017;[Accepted] doi:10.1083/jcb.201703103
Epub:
Not Epub
Abstract:
Activated danger or pathogen sensors trigger assembly of the inflammasome adaptor ASC into specks, large signaling platforms...
Link:
http://jcb.rupress.org/content/early/2017/07/11/jcb.201703103
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kuri P, Schieber NL, Thumberger T, Wittbrodt J, Schwab Y, Leptin M. Dynamics of in vivo ASC speck formation. J Cell Bio. 2017;[Accepted] doi:10.1083/jcb.201703103.

Application of urine cells in drug intervention for spinal muscular atrophy

Authors:
Zhang Q-J, Lin X, Li J-J, Lu Y-Q, Guo X-X, Dong E-L, Zhao M, He J, Wang N, Chen W-J
Citation:
Exp Therap Med. 2017;[accepted] doi:10.3892/etm.2017.4791
Epub:
Yes
Abstract:
Spinal muscular atrophy (SMA) is a lethal childhood neurodegenerative disorder that is caused by the homozygous deletion of...
Link:
https://www.spandidos-publications.com/10.3892/etm.2017.4791
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: primary urine cells
Citation Extract:
Zhang Q-J, Lin X, Li J-J, Lu Y-Q, Guo X-X, Dong E-L, Zhao M, He J, Wang N, Chen W-J. Application of urine cells in drug intervention for spinal muscular atrophy. Exp Therap Med. 2017;[accepted] doi:10.3892/etm.2017.4791.

NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish

Authors:
Yang C-H, Yeh Y-J, Wang J-Y, Liu Y-W, Chen Y-L, Cheng H-W, Cheng C-M, Chuang Y-J, Yuh C-H, Chen Y-R
Citation:
Sci Rep. 2017;7:5241. doi:10.1038/s41598-017-05584-7
Epub:
Not Epub
Abstract:
Expression of neuroendocrine-associated phosphatase (NEAP, also named as dual specificity phosphatase 26, [DUSP26]) is...
Link:
https://www.nature.com/articles/s41598-017-05584-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang C-H, Yeh Y-J, Wang J-Y, Liu Y-W, Chen Y-L, Cheng H-W, Cheng C-M, Chuang Y-J, Yuh C-H, Chen Y-R. NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish. Sci Rep. 2017;7:5241. doi:10.1038/s41598-017-05584-7.

Zebrafish slc30a10 deficiency revealed a novel compensatory mechanism of Atp2c1 in maintaining manganese homeostasis

Authors:
Xia Z, Wei J, Li Y, Wang J, Li W, Wang K, Hong X, Zhao L, Chen C, Min J, Wang F
Citation:
PLoS Genet. 2017 Jul 10;13(7):e1006892. doi: 10.1371/journal.pgen.1006892. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Recent studies found that mutations in the human SLC30A10 gene, which encodes a manganese (Mn) efflux transporter, are...
Link:
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1006892
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xia Z, Wei J, Li Y, Wang J, Li W, Wang K, Hong X, Zhao L, Chen C, Min J, Wang F. Zebrafish slc30a10 deficiency revealed a novel compensatory mechanism of Atp2c1 in maintaining manganese homeostasis. PLoS Genet. 2017 Jul 10;13(7):e1006892. doi: 10.1371/journal.pgen.1006892. [Epub ahead of print].

Imaging neural development in embryonic and larval sea urchins

Authors:
Krupke O, Yaguchi S, Yaguchi J, Burke RD
Citation:
Methods Mol Biol. 2014;1128:147-60. doi: 10.1007/978-1-62703-974-1_9
Epub:
Not Epub
Abstract:
Imaging is a critical tool in neuroscience, and our understanding of the structure and function of sea urchin nervous systems...
Link:
https://link.springer.com/protocol/10.1007/978-1-62703-974-1_9
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Krupke O, Yaguchi S, Yaguchi J, Burke RD. Imaging neural development in embryonic and larval sea urchins. Methods Mol Biol. 2014;1128:147-60. doi: 10.1007/978-1-62703-974-1_9.

The 16p11.2 homologs fam57ba and doc2a generate certain brain and body phenotypes

Authors:
McCammon JM, Blaker-Lee A, Chen X, Sive H
Citation:
Hum Mol Genet. 2017;[Epub ahead of print] doi:10.1093/hmg/ddx255
Epub:
Yes
Abstract:
Deletion of the 16p11.2 CNV affects 25 core genes and is associated with multiple symptoms affecting brain and body, including...
Link:
https://academic.oup.com/hmg/article/doi/10.1093/hmg/ddx255/3932275/The-16p11-2-homologs-fam57ba-and-doc2a-generate
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McCammon JM, Blaker-Lee A, Chen X, Sive H. The 16p11.2 homologs fam57ba and doc2a generate certain brain and body phenotypes. Hum Mol Genet. 2017;[Epub ahead of print] doi:10.1093/hmg/ddx255.

Clock1a affects mesoderm development and primitive hematopoiesis by regulating Nodal-Smad3 signalings in the zebrafish embryo

Authors:
Bian SS, Zheng XL, Sun HQ, Chen JH, Lu YL, Liu YQ, Tao DC, Ma YX
Citation:
J Biol Chem. 2017 Jul 7. pii: jbc.M117.794289. doi: 10.1074/jbc.M117.794289. [Epub ahead of print]
Epub:
Yes
Abstract:
Circadian clock and Smad2/3/4-mediated Nodal signaling regulate multiple physiological and pathological processes. However, it...
Link:
http://www.jbc.org/content/early/2017/07/07/jbc.M117.794289.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bian SS, Zheng XL, Sun HQ, Chen JH, Lu YL, Liu YQ, Tao DC, Ma YX. Clock1a affects mesoderm development and primitive hematopoiesis by regulating Nodal-Smad3 signalings in the zebrafish embryo. J Biol Chem. 2017 Jul 7. pii: jbc.M117.794289. doi: 10.1074/jbc.M117.794289. [Epub ahead of print].

DYRK2 displays muscle fiber type specific function during zebrafish early somitogenesis

Authors:
Sun W, Jiao S, Tan X, Zhang P, You F
Citation:
Int J Dev Biol. 2017;61(6-7):459-463. doi: 10.1387/ijdb.160175sj
Epub:
Not Epub
Abstract:
Dual specificity tyrosine-phosphorylation regulated kinase 2 (DYRK2) is a serine/threonine kinase. In zebrafish, DYRK2 is...
Link:
http://www.ijdb.ehu.es/web/paper/160175sj/dyrk2-displays-muscle-fiber-type-specific-function-during-zebrafish-early-somitogenesis
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun W, Jiao S, Tan X, Zhang P, You F. DYRK2 displays muscle fiber type specific function during zebrafish early somitogenesis. Int J Dev Biol. 2017;61(6-7):459-463. doi: 10.1387/ijdb.160175sj.

Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy

Authors:
Marquardt A, Al-Dabet MM, Ghosh S, Kohli S, Manoharan J, ElWakiel A, Gadi I, Bock F, Nazir S, Wang H, Lindquist JA, Nawroth PP, Madhusudhan T, Mertens PR, Shahzad K, Isermann B
Citation:
J Am Soc Nephrol. 2017 Jul 10. pii: ASN.2016101123. doi: 10.1681/ASN.2016101123. [Epub ahead of print]
Epub:
Yes
Abstract:
Established therapies for diabetic nephropathy (dNP) delay but do not prevent its progression. The shortage of established...
Link:
http://jasn.asnjournals.org/content/early/2017/07/07/ASN.2016101123.abstract
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Marquardt A, Al-Dabet MM, Ghosh S, Kohli S, Manoharan J, ElWakiel A, Gadi I, Bock F, Nazir S, Wang H, Lindquist JA, Nawroth PP, Madhusudhan T, Mertens PR, Shahzad K, Isermann B. Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy. J Am Soc Nephrol. 2017 Jul 10. pii: ASN.2016101123. doi: 10.1681/ASN.2016101123. [Epub ahead of print].

Role of Mad2 expression during the early development of the sea urchin

Authors:
Bronchain O, Jdey W, Caraty L, Ciapa
Citation:
Int J Dev Biol. B2017;61(6-7):451-457. doi: 10.1387/ijdb.170053bc
Epub:
Not Epub
Abstract:
Mitotic arrest deficient 2 (Mad2) belongs to the spindle assembly checkpoint (SAC), a mechanism that blocks progression of the...
Link:
http://www.ijdb.ehu.es/web/paper/170053bc/role-of-mad2-expression-during-the-early-development-of-the-sea-urchin
Delivery Method:
microinjection
Organism or Cell Type:
Paracentrotus lividus (sea urchin)
Citation Extract:
Bronchain O, Jdey W, Caraty L, Ciapa. Role of Mad2 expression during the early development of the sea urchin. Int J Dev Biol. B2017;61(6-7):451-457. doi: 10.1387/ijdb.170053bc.

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