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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system

Authors:
Han Y, Xiong Y, Shi X, Wu J, Zhao Y, Jiang J
Citation:
PLoS Biol. 2017 Aug 4;15(8):e2002063. doi: 10.1371/journal.pbio.2002063. eCollection 2017 Aug
Epub:
Not Epub
Abstract:
Hedgehog (Hh) signaling in vertebrates depends on primary cilia. Upon stimulation, Hh pathway components, including Gli...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Han Y, Xiong Y, Shi X, Wu J, Zhao Y, Jiang J. Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system. PLoS Biol. 2017 Aug 4;15(8):e2002063. doi: 10.1371/journal.pbio.2002063. eCollection 2017 Aug.

CBFβ initiates the hematopoietic stem cell program without obligatory binding to RUNX

Authors:
Ciau-Uitz A, Pinheiro P, Kirmizitas A, Fernandez C, Patient R
Citation:
bioRxiv. 2017;[preprint] doi:10.1101/172957
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) emerge from hemogenic endothelium (HE) localised in the embryonic dorsal aorta (DA). Here we...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ciau-Uitz A, Pinheiro P, Kirmizitas A, Fernandez C, Patient R. CBFβ initiates the hematopoietic stem cell program without obligatory binding to RUNX. bioRxiv. 2017;[preprint] doi:10.1101/172957.

Zebrafish Znfl1 proteins control the expression of hoxb1b gene in the posterior neuroectoderm by acting upstream of pou5f3 and sall4 genes

Authors:
Dong X, Li J, He L, Gu C, Jia W, Yue Y, Li J, Zhang Q, Chu L, Zhao Q
Citation:
J Biol Chem. 2017 Aug 4;292(31):13045-13055. doi: 10.1074/jbc.M117.777094. Epub 2017 Jun 16
Epub:
Not Epub
Abstract:
Transcription factors play crucial roles in patterning posterior neuroectoderm. Previously, zinc finger transcription factor...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dong X, Li J, He L, Gu C, Jia W, Yue Y, Li J, Zhang Q, Chu L, Zhao Q. Zebrafish Znfl1 proteins control the expression of hoxb1b gene in the posterior neuroectoderm by acting upstream of pou5f3 and sall4 genes. J Biol Chem. 2017 Aug 4;292(31):13045-13055. doi: 10.1074/jbc.M117.777094. Epub 2017 Jun 16.

hmmr mediates anterior neural tube closure and morphogenesis in the frog Xenopus

Authors:
Prager A, Hagenlocher C, Ott T, Schambony A, Feistel K
Citation:
Dev Biol. 2017 Aug 1. pii: S0012-1606(17)30032-5. doi: 10.1016/j.ydbio.2017.07.020. [Epub ahead of print]
Epub:
Yes
Abstract:
Development of the central nervous system requires orchestration of morphogenetic processes which drive elevation and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Prager A, Hagenlocher C, Ott T, Schambony A, Feistel K. hmmr mediates anterior neural tube closure and morphogenesis in the frog Xenopus. Dev Biol. 2017 Aug 1. pii: S0012-1606(17)30032-5. doi: 10.1016/j.ydbio.2017.07.020. [Epub ahead of print].

Claudin5a is required for proper inflation of Kupffer's vesicle lumen and organ laterality

Authors:
Kim JG, Bae SJ, Lee HS, Park JH, Kim KW
Citation:
PLoS One. 2017 Aug 3;12(8):e0182047. doi: 10.1371/journal.pone.0182047. eCollection 2017
Epub:
Not Epub
Abstract:
Left-right asymmetric organ development is critical to establish a proper body plan of vertebrates. In zebrafish, the Kupffer...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim JG, Bae SJ, Lee HS, Park JH, Kim KW. Claudin5a is required for proper inflation of Kupffer's vesicle lumen and organ laterality. PLoS One. 2017 Aug 3;12(8):e0182047. doi: 10.1371/journal.pone.0182047. eCollection 2017.

In Vitro Modulation of Endogenous Alternative Splicing Using Splice-Switching Antisense Oligonucleotides

Authors:
Park JE, Cartegni L
Citation:
Methods Mol Biol. 2017;1648:39-52. doi: 10.1007/978-1-4939-7204-3_4
Epub:
Not Epub
Abstract:
Regulation of alternative splicing can be harnessed by antisense-based compounds to control gene expression. Antisense-mediated...
Organism or Cell Type:
cell culture
Citation Extract:
Park JE, Cartegni L. In Vitro Modulation of Endogenous Alternative Splicing Using Splice-Switching Antisense Oligonucleotides. Methods Mol Biol. 2017;1648:39-52. doi: 10.1007/978-1-4939-7204-3_4.

N1-Src kinase is required for primary neurogenesis in Xenopus tropicalis

Authors:
Lewis PA, Bradley IC, Pizzey AR, Isaacs HV, Evans GJO
Citation:
J Neurosci. 2017;[Published online] doi:10.1523/JNEUROSCI.3881-16.2017
Epub:
Not Epub
Abstract:
The presence of the neuronal-specific N1-Src splice variant of the C-Src tyrosine kinase is conserved through vertebrate...
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Lewis PA, Bradley IC, Pizzey AR, Isaacs HV, Evans GJO. N1-Src kinase is required for primary neurogenesis in Xenopus tropicalis. J Neurosci. 2017;[Published online] doi:10.1523/JNEUROSCI.3881-16.2017.

Metformin Inhibits Cyst Formation in a Zebrafish Model of Polycystin-2 Deficiency

Authors:
Chang M-Y, Ma T-L, Hung C-C, Tian Y-C, Chen Y-C, Yang C-W, Cheng Y-C
Citation:
Sci Rep. 2017;7:7161. doi:10.1038/s41598-017-07300-x
Epub:
Not Epub
Abstract:
Autosomal dominant polycystic kidney disease (ADPKD) is a common kidney disease caused by mutations in PKD1 or PKD2. Metformin...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chang M-Y, Ma T-L, Hung C-C, Tian Y-C, Chen Y-C, Yang C-W, Cheng Y-C. Metformin Inhibits Cyst Formation in a Zebrafish Model of Polycystin-2 Deficiency. Sci Rep. 2017;7:7161. doi:10.1038/s41598-017-07300-x.

Flow-Responsive VEGFR-PKCɛ Signaling Mediates Glycolytic Metabolites for Vascular Repair

Authors:
Baek KI, Li R, Jen N, Choi H, Kaboodrangi A, Ping P, Liem D, Beebe T, Hsiai TK
Citation:
Antioxid Redox Signal. 2017 Aug 1. doi: 10.1089/ars.2017.7044. [Epub ahead of print]
Epub:
Yes
Abstract:
Aims - Hemodynamic shear stress participates in maintaining vascular redox status. Elucidating flow-mediated endothelial...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Baek KI, Li R, Jen N, Choi H, Kaboodrangi A, Ping P, Liem D, Beebe T, Hsiai TK. Flow-Responsive VEGFR-PKCɛ Signaling Mediates Glycolytic Metabolites for Vascular Repair. Antioxid Redox Signal. 2017 Aug 1. doi: 10.1089/ars.2017.7044. [Epub ahead of print].

Nanog suppresses the expression of vasa by directly regulating nlk1 in the early zebrafish embryo

Authors:
Liu Y, Xue W, Zhu L, Ye D, Zhu X, Wang H, Sun Y, Deng F
Citation:
Biochimie. 2017 Jul 28. pii: S0300-9084(17)30185-2. doi: 10.1016/j.biochi.2017.07.014. [Epub ahead of print]
Epub:
Yes
Abstract:
Nanog is a homeodomain transcription factor that is essential for maintenance of pluripotency and self-renewal of embryonic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu Y, Xue W, Zhu L, Ye D, Zhu X, Wang H, Sun Y, Deng F. Nanog suppresses the expression of vasa by directly regulating nlk1 in the early zebrafish embryo. Biochimie. 2017 Jul 28. pii: S0300-9084(17)30185-2. doi: 10.1016/j.biochi.2017.07.014. [Epub ahead of print].

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