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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Epigenetic regulation of left-right asymmetry by DNA methylation

Authors:
Wang L, Liu Z, Lin H, Ma D, Tao Q, Liu F
Citation:
EMBO J. 2017;[Epub ahead of print] doi:10.15252/embj.201796580
Epub:
Yes
Abstract:
DNA methylation is a major epigenetic modification; however, the precise role of DNA methylation in vertebrate development is...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Wang L, Liu Z, Lin H, Ma D, Tao Q, Liu F. Epigenetic regulation of left-right asymmetry by DNA methylation. EMBO J. 2017;[Epub ahead of print] doi:10.15252/embj.201796580.

PaxA, but not PaxC, is required for cnidocyte development in the sea anemone Nematostella vectensis

Authors:
Babonis LS, Martindale MQ
Citation:
Evodevo. 2017 Sep 4;8:14. doi: 10.1186/s13227-017-0077-7. eCollection 2017
Epub:
Not Epub
Abstract:
BACKGROUND: Pax genes are a family of conserved transcription factors that regulate many aspects of developmental morphogenesis...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Babonis LS, Martindale MQ. PaxA, but not PaxC, is required for cnidocyte development in the sea anemone Nematostella vectensis. Evodevo. 2017 Sep 4;8:14. doi: 10.1186/s13227-017-0077-7. eCollection 2017.

Identification of a new adtrp1-tfpi regulatory axis for the specification of primitive myelopoiesis and definitive hematopoiesis

Authors:
Wang L, Wang X, Wang L, Yousaf M, Li J, Zuo M, Yang Z, Gou D, Bao B, Li L, Xiang N, Jia H, Xu C, Chen Q, Wang QK
Citation:
FASEB J. 2017 Sep 6. pii: fj.201700166RR. doi: 10.1096/fj.201700166RR. [Epub ahead of print]
Epub:
Yes
Abstract:
A genomic variant in the human ADTRP [androgen-dependent tissue factor (TF) pathway inhibitor (TFPI) regulating protein] gene...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang L, Wang X, Wang L, Yousaf M, Li J, Zuo M, Yang Z, Gou D, Bao B, Li L, Xiang N, Jia H, Xu C, Chen Q, Wang QK. Identification of a new adtrp1-tfpi regulatory axis for the specification of primitive myelopoiesis and definitive hematopoiesis. FASEB J. 2017 Sep 6. pii: fj.201700166RR. doi: 10.1096/fj.201700166RR. [Epub ahead of print].

m6A modulates haematopoietic stem and progenitor cell specification

Authors:
Zhang C, Chen Y, Sun B, Wang L, Yang Y, Ma D, Lv J, Heng J, Ding Y, Xue Y, Lu X, Xiao W, Yang YG, Liu F
Citation:
Nature. 2017 Sep 6. doi: 10.1038/nature23883. [Epub ahead of print]
Epub:
Yes
Abstract:
N6-methyladenosine (m6A) has been identified as the most abundant modification on eukaryote messenger RNA (mRNA). Although the...
Citation Extract:
Zhang C, Chen Y, Sun B, Wang L, Yang Y, Ma D, Lv J, Heng J, Ding Y, Xue Y, Lu X, Xiao W, Yang YG, Liu F. m6A modulates haematopoietic stem and progenitor cell specification. Nature. 2017 Sep 6. doi: 10.1038/nature23883. [Epub ahead of print].

Autogenous Cross-Regulation Of Quaking mRNA Processing And Translation Balances Quaking Functions In Splicing And Translation

Authors:
Fagg WS, Liu N, Fair JH, Shiue L, Katzmann S, Donohue J-P, Ares M
Citation:
bioRxiv. 2017. doi:doi.org/10.1101/127936
Epub:
Not Epub
Abstract:
Quaking protein isoforms arise from a single Quaking gene, and bind the same RNA motif to regulate splicing, translation, decay...
Organism or Cell Type:
cell culture: mouse myoblasts
Citation Extract:
Fagg WS, Liu N, Fair JH, Shiue L, Katzmann S, Donohue J-P, Ares M. Autogenous Cross-Regulation Of Quaking mRNA Processing And Translation Balances Quaking Functions In Splicing And Translation. bioRxiv. 2017. doi:doi.org/10.1101/127936.

Endodermal germ-layer formation through active actin-driven migration triggered by N-cadherin

Authors:
Giger FA, David NB
Citation:
Proc Natl Acad Sci U S A. 2017 Sep 5. pii: 201708116. doi: 10.1073/pnas.1708116114. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Germ-layer formation during gastrulation is both a fundamental step of development and a paradigm for tissue formation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Giger FA, David NB. Endodermal germ-layer formation through active actin-driven migration triggered by N-cadherin. Proc Natl Acad Sci U S A. 2017 Sep 5. pii: 201708116. doi: 10.1073/pnas.1708116114. [Epub ahead of print].

A right-handed signalling pathway drives heart looping in vertebrates

Authors:
Ocaña OH, Coskun H, Minguillón C, Murawala P, Tanaka AM, Galcerán J, Muñoz-Chápuli R, Nieto MA
Citation:
Nature. 2017;549:86-90. doi:doi:10.1038/nature23454
Epub:
Not Epub
Abstract:
Most animals show external bilateral symmetry, which hinders the observation of multiple internal left–right (L/R) asymmetries...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ocaña OH, Coskun H, Minguillón C, Murawala P, Tanaka AM, Galcerán J, Muñoz-Chápuli R, Nieto MA. A right-handed signalling pathway drives heart looping in vertebrates. Nature. 2017;549:86-90. doi:doi:10.1038/nature23454.

NQO2 inhibition relieves ROS effects on mouse oocyte meiotic maturation and embryo development

Authors:
Chen D, Li X, Xiaoyun Liu X, Liu X, Jiang X, Du J, Wang Q, Liang Y, Ma W
Citation:
Biol Reproduc. 2017;[Accepted manuscript] doi:10.1093/biolre/iox098
Epub:
Yes
Abstract:
NRH: quinone oxidoreductase 2 (NQO2) is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron...
Organism or Cell Type:
mouse oocyte
Citation Extract:
Chen D, Li X, Xiaoyun Liu X, Liu X, Jiang X, Du J, Wang Q, Liang Y, Ma W. NQO2 inhibition relieves ROS effects on mouse oocyte meiotic maturation and embryo development. Biol Reproduc. 2017;[Accepted manuscript] doi:10.1093/biolre/iox098.

A novel inducible mutagenesis screen enables to isolate and clone both embryonic and adult zebrafish mutants

Authors:
Ma Z, Zhu P, Pang M, Guo L, Chang N, Zheng J, Zhu X, Gao C, Huang H, Cui Z, Xiong JW, Peng J, Chen J
Citation:
Sci Rep. 2017 Sep 4;7(1):10381. doi: 10.1038/s41598-017-10968-w
Epub:
Not Epub
Abstract:
Conventional genetic screens for recessive mutants are inadequate for studying biological processes in the adult vertebrate due...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma Z, Zhu P, Pang M, Guo L, Chang N, Zheng J, Zhu X, Gao C, Huang H, Cui Z, Xiong JW, Peng J, Chen J. A novel inducible mutagenesis screen enables to isolate and clone both embryonic and adult zebrafish mutants. Sci Rep. 2017 Sep 4;7(1):10381. doi: 10.1038/s41598-017-10968-w.

Prdm13 forms a feedback loop with Ptf1a and is required for glycinergic amacrine cell genesis in the Xenopus Retina

Authors:
Bessodes N, Parain K, Bronchain O, Bellefroid EJ, Perron M
Citation:
Neural Dev. 2017 Sep 1;12(1):16. doi: 10.1186/s13064-017-0093-2
Epub:
Not Epub
Abstract:
BACKGROUND: Amacrine interneurons that modulate synaptic plasticity between bipolar and ganglion cells constitute the most...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bessodes N, Parain K, Bronchain O, Bellefroid EJ, Perron M. Prdm13 forms a feedback loop with Ptf1a and is required for glycinergic amacrine cell genesis in the Xenopus Retina. Neural Dev. 2017 Sep 1;12(1):16. doi: 10.1186/s13064-017-0093-2.

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