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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Delayed APC/C activation extends the first mitosis of mouse embryos

Authors:
Ajduk A, Strauss B, Pines J, Zernicka-Goetz M
Citation:
Sci Rep. 2017;7:9682. doi:10.1038/s41598-017-09526-1
Epub:
Not Epub
Abstract:
The correct temporal regulation of mitosis underpins genomic stability because it ensures the alignment of chromosomes on the...
Link:
https://www.nature.com/articles/s41598-017-09526-1
Delivery Method:
microinjection
Organism or Cell Type:
mouse embryo
Citation Extract:
Ajduk A, Strauss B, Pines J, Zernicka-Goetz M. Delayed APC/C activation extends the first mitosis of mouse embryos. Sci Rep. 2017;7:9682. doi:10.1038/s41598-017-09526-1.

Novel Heparin Receptor Transmembrane Protein 184a Regulates Angiogenesis in the Adult Zebrafish Caudal Fin

Authors:
Farwell SLN, Reylander KG, Iovine MK, Lowe-Krentz LJ
Citation:
Front Physiol. 2017;[Epub ahead of print] doi:doi: 10.3389/fphys.2017.00671
Epub:
Yes
Abstract:
Transmembrane protein 184A (TMEM184A) was recently identified as the heparin receptor in vascular cells. Heparin binds...
Link:
http://journal.frontiersin.org/article/10.3389/fphys.2017.00671/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Farwell SLN, Reylander KG, Iovine MK, Lowe-Krentz LJ. Novel Heparin Receptor Transmembrane Protein 184a Regulates Angiogenesis in the Adult Zebrafish Caudal Fin. Front Physiol. 2017;[Epub ahead of print] doi:doi: 10.3389/fphys.2017.00671.

Mechanics of Fluid-Filled Interstitial Gaps. II. Gap Characteristics in Xenopus Embryonic Ectoderm

Authors:
Barua D, Parent SE, Winklbauer R
Citation:
Biophys J. 2017 Aug 22;113(4):923-936. doi: 10.1016/j.bpj.2017.06.063
Epub:
Not Epub
Abstract:
The ectoderm of the Xenopus embryo is permeated by a network of channels that appear in histological sections as interstitial...
Link:
http://www.cell.com/biophysj/abstract/S0006-3495(17)30749-X
Organism or Cell Type:
Xenopus
Citation Extract:
Barua D, Parent SE, Winklbauer R. Mechanics of Fluid-Filled Interstitial Gaps. II. Gap Characteristics in Xenopus Embryonic Ectoderm. Biophys J. 2017 Aug 22;113(4):923-936. doi: 10.1016/j.bpj.2017.06.063.

Peroxiredoxin1, a novel regulator of pronephros development, influences retinoic acid and Wnt signaling by controlling ROS levels

Authors:
Chae S, Lee HK, Kim YK, Jung Sim H, Ji Y, Kim C, Ismail T, Park JW, Kwon OS, Kang BS, Lee DS, Bae JS, Kim SH, Min KJ, Kyu Kwon T, Park MJ, Han JK, Kwon T, Park TJ, Lee HS
Citation:
Sci Rep. 2017 Aug 21;7(1):8874. doi: 10.1038/s41598-017-09262-6
Epub:
Not Epub
Abstract:
Peroxiredoxin1 (Prdx1) is an antioxidant enzyme belonging to the peroxiredoxin family of proteins. Prdx1 catalyzes the...
Link:
https://www.nature.com/articles/s41598-017-09262-6
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chae S, Lee HK, Kim YK, Jung Sim H, Ji Y, Kim C, Ismail T, Park JW, Kwon OS, Kang BS, Lee DS, Bae JS, Kim SH, Min KJ, Kyu Kwon T, Park MJ, Han JK, Kwon T, Park TJ, Lee HS. Peroxiredoxin1, a novel regulator of pronephros development, influences retinoic acid and Wnt signaling by controlling ROS levels. Sci Rep. 2017 Aug 21;7(1):8874. doi: 10.1038/s41598-017-09262-6.

Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis

Authors:
Kardon JR, Yien YY, Huston NC, Branco DS, Hildick-Smith GJ, Rhee KY, Paw BH, Baker TA
Citation:
Cell. 2015 May 7;161(4):858-67. doi: 10.1016/j.cell.2015.04.017
Epub:
Not Epub
Abstract:
The mitochondrion maintains and regulates its proteome with chaperones primarily inherited from its bacterial endosymbiont...
Link:
http://www.cell.com/cell/fulltext/S0092-8674(15)00434-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kardon JR, Yien YY, Huston NC, Branco DS, Hildick-Smith GJ, Rhee KY, Paw BH, Baker TA. Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis. Cell. 2015 May 7;161(4):858-67. doi: 10.1016/j.cell.2015.04.017.

Insm1a Is Required for Zebrafish Posterior Lateral Line Development

Authors:
He Y, Lu X, Qian F, Liu D, Chai R, Li H
Citation:
Front Mol Neurosci. 2017 Aug 2;10:241. doi: 10.3389/fnmol.2017.00241. eCollection 2017
Epub:
Not Epub
Abstract:
Insulinoma-associated 1 (Insm1), a zinc-finger transcription factor, is widely expressed in the developing nervous system and...
Link:
http://journal.frontiersin.org/article/10.3389/fnmol.2017.00241/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
He Y, Lu X, Qian F, Liu D, Chai R, Li H. Insm1a Is Required for Zebrafish Posterior Lateral Line Development. Front Mol Neurosci. 2017 Aug 2;10:241. doi: 10.3389/fnmol.2017.00241. eCollection 2017.

Loss of zinc finger MYND-type containing 10 (zmynd10) affects cilia integrity and axonemal localization of dynein arms, resulting in ciliary dysmotility, polycystic kidney and scoliosis in medaka (Oryzias latipes)

Authors:
Kobayashi D, Asano-Hoshino A, Nakakura T, Nishimaki T, Ansai S, Kinoshita M, Ogawa M, Hagiwara H, Yokoyama T
Citation:
Dev Biol. 2017 Aug 16. pii: S0012-1606(17)30202-6. doi: 10.1016/j.ydbio.2017.08.016. [Epub ahead of print]
Epub:
Yes
Abstract:
Cilia and flagella are hair-like organelles that project from the cell surface and play important roles in motility and sensory...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160617302026
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Kobayashi D, Asano-Hoshino A, Nakakura T, Nishimaki T, Ansai S, Kinoshita M, Ogawa M, Hagiwara H, Yokoyama T. Loss of zinc finger MYND-type containing 10 (zmynd10) affects cilia integrity and axonemal localization of dynein arms, resulting in ciliary dysmotility, polycystic kidney and scoliosis in medaka (Oryzias latipes). Dev Biol. 2017 Aug 16. pii: S0012-1606(17)30202-6. doi: 10.1016/j.ydbio.2017.08.016. [Epub ahead of print].

ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus

Authors:
Ma P, Ren B, Yang X, Sun B, Liu X, Kong Q, Li C, Mao B
Citation:
Open Biol. 2017 Aug;7(8). pii: 170122. doi: 10.1098/rsob.170122. Epub 2017 Aug 16
Epub:
Not Epub
Abstract:
Bone morphogenetic proteins (BMPs) play vital roles in regulating stem cell maintenance, differentiation and embryonic...
Link:
http://rsob.royalsocietypublishing.org/content/7/8/170122
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ma P, Ren B, Yang X, Sun B, Liu X, Kong Q, Li C, Mao B. ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus. Open Biol. 2017 Aug;7(8). pii: 170122. doi: 10.1098/rsob.170122. Epub 2017 Aug 16.

Homozygous Mutations in TBC1D23 Lead to a Non-degenerative Form of Pontocerebellar Hypoplasia

Authors:
Marin-Valencia I, Gerondopoulos A, Zaki MS, Ben-Omran T, Almureikhi M, Demir E, Guemez-Gamboa A, Gregor A,Issa MY, Appelhof B, Roosing S, Musaev D, Rosti B, Wirth S, Stanley V, Baas F, Barr FA, Gleeson JG
Citation:
Am J Hum Genet. 2017. {Epub ahead of print] doi:10.1016/j.ajhg.2017.07.015
Epub:
Yes
Abstract:
Pontocerebellar hypoplasia (PCH) represents a group of recessive developmental disorders characterized by impaired growth of...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297(17)30293-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marin-Valencia I, Gerondopoulos A, Zaki MS, Ben-Omran T, Almureikhi M, Demir E, Guemez-Gamboa A, Gregor A,Issa MY, Appelhof B, Roosing S, Musaev D, Rosti B, Wirth S, Stanley V, Baas F, Barr FA, Gleeson JG. Homozygous Mutations in TBC1D23 Lead to a Non-degenerative Form of Pontocerebellar Hypoplasia. Am J Hum Genet. 2017. {Epub ahead of print] doi:10.1016/j.ajhg.2017.07.015.

DAN (NBL1) promotes collective neural crest migration by restraining uncontrolled invasion

Authors:
McLennan R, Bailey CM, Schumacher LJ, Teddy JM, Morrison JA, Kasemeier-Kulesa JC, Wolfe LA, Gogol MM, Baker RE, Maini PK, Kulesa PM
Citation:
J Cell Biol. 2017 Aug 15. pii: jcb.201612169. doi: 10.1083/jcb.201612169. [Epub ahead of print]
Epub:
Yes
Abstract:
Neural crest cells are both highly migratory and significant to vertebrate organogenesis. However, the signals that regulate...
Link:
http://jcb.rupress.org/content/early/2017/08/14/jcb.201612169
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
McLennan R, Bailey CM, Schumacher LJ, Teddy JM, Morrison JA, Kasemeier-Kulesa JC, Wolfe LA, Gogol MM, Baker RE, Maini PK, Kulesa PM. DAN (NBL1) promotes collective neural crest migration by restraining uncontrolled invasion. J Cell Biol. 2017 Aug 15. pii: jcb.201612169. doi: 10.1083/jcb.201612169. [Epub ahead of print].

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