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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12158 scientific papers returned from the database with the search filters currently being used below.
There are 12158 scientific papers returned from the database with the search filters currently being used below.
Up-regulation of autophagy-related gene 5 (ATG5) protects dopaminergic neurons in a zebrafish model of Parkinson's disease
Citation:
J Biol Chem. 2017;292:18062-74. doi:10.1074/jbc.M116.764795 Epub:
Not Epub Abstract:
Parkinson's disease (PD) is one of the most epidemic neurodegenerative diseases and is characterized by movement disorders... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hu Z-y, Chen B, Zhang J-p, Ma Y-y. Up-regulation of autophagy-related gene 5 (ATG5) protects dopaminergic neurons in a zebrafish model of Parkinson's disease. J Biol Chem. 2017;292:18062-74. doi:10.1074/jbc.M116.764795. |
Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations
Citation:
Am J Hum Genet. 2017;101(5):789-802. doi:10.1016/j.ajhg.2017.09.018 Epub:
Not Epub Abstract:
Renal agenesis and hypodysplasia (RHD) are major causes of pediatric chronic kidney disease and are highly genetically... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sanna-Cherchi S, Khan K, Westland R, Krithivasan P, Fievet L, Rasouly HM, Ionita-Laza I, Capone VP, Fasel DA, Kiryluk K, Kamalakaran S, Bodria M, Otto EA, Sampson G, Gillies CE, Vega-Warner V, Vukojevic K, Pediaditakis I, Makar GS, Mitrotti A, Verbitsky M, Martino J, Liu Q, Na Y-J, Goj V, Ardissino G, Gigante M, Gesualdo L, Janezcko M, Zaniew M, Mendelsohn CL, Shril S, Hildebrandt F, van Wijk JAE, Arapovic A, Saraga M, Allegri L, Izzi C, Scolari F, Tasic V, Ghiggeri GM, Latos-Bielenska A, Kiryluk A-M, Mane S, Goldstein DB, Lifton RP, Katsanis N, Davis EE, Gharavi AG. Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations. Am J Hum Genet. 2017;101(5):789-802. doi:10.1016/j.ajhg.2017.09.018. |
Fyn-dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development
Citation:
FEBS J. 2017 Nov 1. doi: 10.1111/febs.14313. [Epub ahead of print] Epub:
Yes Abstract:
Plexins (Plxns) are semaphorin (Sema) receptors that play important signaling roles, particularly in the developing nervous... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: St Clair RM, Emerson SE, D'Elia KP, Weir ME, Schmoker AM, Ebert AM, Ballif BA. Fyn-dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development. FEBS J. 2017 Nov 1. doi: 10.1111/febs.14313. [Epub ahead of print]. |
Znf703, a novel target of Pax3 and Zic1, regulates hindbrain and neural crest development in Xenopus
Citation:
Genesis. 2017 Oct 31. doi: 10.1002/dvg.23082. [Epub ahead of print] Epub:
Yes Abstract:
The transcription factors Pax3 and Zic1 are critical to specify the neural plate border and to promote neural crest formation.... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Hong CS, Saint-Jeannet JP. Znf703, a novel target of Pax3 and Zic1, regulates hindbrain and neural crest development in Xenopus. Genesis. 2017 Oct 31. doi: 10.1002/dvg.23082. [Epub ahead of print]. |
Cohesin mediates Esco2-dependent transcriptional regulation in zebrafish regenerating fin model of Roberts syndrome
Citation:
Biol Open. 2017 Oct 30. pii: bio.026013. doi: 10.1242/bio.026013. [Epub ahead of print] Epub:
Yes Abstract:
Robert syndrome (RBS) and Cornelia de Lange syndrome (CdLS) are human developmental disorders characterized by craniofacial... Delivery Method:
microinjection, electroporation Organism or Cell Type:
zebrafish Citation Extract:
Banerji R, Skibbens RV, Iovine MK. Cohesin mediates Esco2-dependent transcriptional regulation in zebrafish regenerating fin model of Roberts syndrome. Biol Open. 2017 Oct 30. pii: bio.026013. doi: 10.1242/bio.026013. [Epub ahead of print]. |
Salmonella exploits the host endolysosomal tethering factor HOPS complex to promote its intravacuolar replication
Citation:
PLoS Pathog. 2017;13(10):e1006700. doi:10.1371/journal.ppat.1006700 Epub:
Not Epub Abstract:
Salmonella enterica serovar typhimurium extensively remodels the host late endocytic compartments to establish its vacuolar... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Sindhwani A, Arya SB, Kaur H, Jagga D, Tuli A, Sharma M. Salmonella exploits the host endolysosomal tethering factor HOPS complex to promote its intravacuolar replication. PLoS Pathog. 2017;13(10):e1006700. doi:10.1371/journal.ppat.1006700. |
Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration
Citation:
Nat Comm. 2017;8:1185. doi:10.1038/s41467-017-01107-0 Epub:
Not Epub Abstract:
Following epithelial-mesenchymal transition, acquisition of avian trunk neural crest cell (NCC) polarity is prerequisite for... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Liu JA, Rao Y, Cheung MPL, Hui M-N, Wu M-H, Chan L-K, Ng IO-L, Niu B, Cheah KSE, Sharma R, Hodgson L, Cheung M. Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration. Nat Comm. 2017;8:1185. doi:10.1038/s41467-017-01107-0. |
A method to quantify mechanobiologic forces during zebrafish cardiac development using 4-D light sheet imaging and computational modeling
Citation:
PLoS Comput Biol. 2017;13(10):e1005828. doi:journal.pcbi.1005828 Epub:
Not Epub Abstract:
Blood flow and mechanical forces in the ventricle are implicated in cardiac development and trabeculation. However, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Vedula V, Lee J, Xu H, Kuo C-CJ, Hsiai TK, Marsden AL. A method to quantify mechanobiologic forces during zebrafish cardiac development using 4-D light sheet imaging and computational modeling. PLoS Comput Biol. 2017;13(10):e1005828. doi:journal.pcbi.1005828. |
Sirt2-BubR1 acetylation pathway mediates the effects of advanced maternal age on oocyte quality
Citation:
Aging Cell. 2017 Oct 25. doi: 10.1111/acel.12698. [Epub ahead of print] Epub:
Yes Abstract:
The level of Sirt2 protein is reduced in oocytes from aged mice, while exogenous expression of Sirt2 could ameliorate the... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Qiu D, Hou X, Han L, Li X, Ge J, Wang Q. Sirt2-BubR1 acetylation pathway mediates the effects of advanced maternal age on oocyte quality. Aging Cell. 2017 Oct 25. doi: 10.1111/acel.12698. [Epub ahead of print]. |
PMO Delivery System Using Bubble Liposomes and Ultrasound Exposure for Duchenne Muscular Dystrophy Treatment
Citation:
Methods Mol Biol. 2018;1687:185-192. doi: 10.1007/978-1-4939-7374-3_13 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a genetic disorder characterized by progressive muscle degeneration, caused by nonsense or... Delivery Method:
bubble liposome & ultrasound Organism or Cell Type:
mice Citation Extract: Negishi Y, Ishii Y, Nirasawa K, Sasaki E, Endo-Takahashi Y, Suzuki R, Maruyama K. PMO Delivery System Using Bubble Liposomes and Ultrasound Exposure for Duchenne Muscular Dystrophy Treatment. Methods Mol Biol. 2018;1687:185-192. doi: 10.1007/978-1-4939-7374-3_13. |