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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Designing Effective Antisense Oligonucleotides for Exon Skipping
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Citation:
Methods Mol Biol. 2018;1687:143-155. doi: 10.1007/978-1-4939-7374-3_10 Epub:
Not Epub Abstract:
During the past 10 years, antisense oligonucleotide-mediated exon skipping and splice modulation have proven to be powerful... Citation Extract: Shimo T, Maruyama R, Yokota T.. Designing Effective Antisense Oligonucleotides for Exon Skipping. Methods Mol Biol. 2018;1687:143-155. doi: 10.1007/978-1-4939-7374-3_10. |
Exon Skipping Therapy Using Phosphorodiamidate Morpholino Oligomers in the mdx52 Mouse Model of Duchenne Muscular Dystrophy
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Citation:
Methods Mol Biol. 2018;1687:123-141. doi: 10.1007/978-1-4939-7374-3_9 Epub:
Not Epub Abstract:
Exon skipping therapy using synthetic DNA-like molecules called antisense oligonucleotides (ASOs) is a promising therapeutic... Delivery Method:
injection Organism or Cell Type:
mice Citation Extract: Miyatake S, Mizobe Y, Takizawa H, Hara Y, Yokota T, Takeda S, Aoki Y. Exon Skipping Therapy Using Phosphorodiamidate Morpholino Oligomers in the mdx52 Mouse Model of Duchenne Muscular Dystrophy. Methods Mol Biol. 2018;1687:123-141. doi: 10.1007/978-1-4939-7374-3_9. |
GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency
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Citation:
PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1708341114 Epub:
Yes Abstract:
To elucidate the molecular basis of BMP4-induced differentiation of human pluripotent stem cells (PSCs) toward progeny with... Delivery Method:
microinjection Organism or Cell Type:
Rhesus macaque (monkey) Citation Extract: Krendl C, Shaposhnikov D, Rishko V, Ori C, Ziegenhain C, Sass S, Simon L, Müller NS, Straub T, Brooks KE, Chavez SL, Enard W, Theis FJ, Drukker M. GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency. PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1708341114. |
The Translation of Cyclin B1 and B2 is Differentially Regulated during Mouse Oocyte Reentry into the Meiotic Cell Cycle
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Citation:
Sci Rep. 2017;7:14077 doi:10.1038/s41598-017-13688-3 Epub:
Not Epub Abstract:
Control of protein turnover is critical for meiotic progression. Using RiboTag immunoprecipitation, RNA binding protein... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Han SJ, Martins JPS, Yang Y, Kang MK, Daldello EMD, Conti M. The Translation of Cyclin B1 and B2 is Differentially Regulated during Mouse Oocyte Reentry into the Meiotic Cell Cycle. Sci Rep. 2017;7:14077 doi:10.1038/s41598-017-13688-3. |
In Vivo Translatome Profiling in Spinal Muscular Atrophy Reveals a Role for SMN Protein in Ribosome Biology
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Citation:
Cell Rep. 2017;21:953-965. doi:10.1016/j.celrep.2017.10.010 Epub:
Not Epub Abstract:
Genetic alterations impacting ubiquitously expressed proteins involved in RNA metabolism often result in neurodegenerative... Delivery Method:
i.v. injection Organism or Cell Type:
mice Citation Extract: Bernabo P, Tebaldi T, Groen EJN, Lane FM, Perenthaler E, Mattedi F, Newbery HJ, Zhou H, Zuccotti P, Potrich V, Shorrock HK, Muntoni F, Quattrone A, Gillingwater TH, Viero G. In Vivo Translatome Profiling in Spinal Muscular Atrophy Reveals a Role for SMN Protein in Ribosome Biology. Cell Rep. 2017;21:953-965. doi:10.1016/j.celrep.2017.10.010. |
Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence
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Citation:
PNAS USA. 2017;114(43):E8996-E9005 doi:10.1073/pnas.1708725114 Epub:
Not Epub Abstract:
Tissue regeneration depends on the timely activation of adult stem cells. In skeletal muscle, the adult stem cells maintain a... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: de Morrée A, van Velthoven CTJ, Gan Q, Salvi JS, Klein JDD, Akimenko I, Quarta M, Biressi S, Rando TA. Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence. PNAS USA. 2017;114(43):E8996-E9005 doi:10.1073/pnas.1708725114. |
Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway
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Citation:
PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1712560114 Epub:
Yes Abstract:
Persistent directional cell migration is involved in animal development and diseases. The small GTPase Rac1 is involved in F-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mizoguchi T, Ikeda S, Watanabe S, Sugawara M, Itoh M. Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway. PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1712560114. |
Placeholder nucleosomes underlie germline-to-embryo DNA methylation reprogramming
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Citation:
BioRxiv. 2017;[preprint] doi:10.1101/204792 Epub:
Not Epub Abstract:
The fate and function of epigenetic marks during the germline-to-embryo transition is a key issue in developmental biology,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Murphy PJ, Wu SF, James CR, Wike CL, Cairns BR. Placeholder nucleosomes underlie germline-to-embryo DNA methylation reprogramming. BioRxiv. 2017;[preprint] doi:10.1101/204792 . |
PFKFB4 control of Akt signaling is essential for premigratory and migratory neural crest formation
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Citation:
Development. 2017 Oct 16. pii: dev.157644. doi: 10.1242/dev.157644. [Epub ahead of print] Epub:
Yes Abstract:
Neural crest (NC) specification comprises an early phase, initiating immature NC progenitors formation at neural plate stage,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Figueiredo AL, Maczkowiak F, Borday C, Pla P, Sittewelle M, Pegoraro C, Monsoro-Burq AH. PFKFB4 control of Akt signaling is essential for premigratory and migratory neural crest formation. Development. 2017 Oct 16. pii: dev.157644. doi: 10.1242/dev.157644. [Epub ahead of print]. |
Zebrafish aversive taste co-receptor is expressed in both chemo- and mechanosensory cells and plays a role in lateral line development
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Citation:
Sci Rep. 2017 Oct 18;7(1):13475. doi: 10.1038/s41598-017-14042-3 Epub:
Not Epub Abstract:
Fishes rely on both chemical and tactile senses to orient themselves to avoid predators, and to detect and taste food. This is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mojib N, Xu J, Bartolek Z, Imhoff B, McCarty NA, Shin CH, Kubanek J. Zebrafish aversive taste co-receptor is expressed in both chemo- and mechanosensory cells and plays a role in lateral line development. Sci Rep. 2017 Oct 18;7(1):13475. doi: 10.1038/s41598-017-14042-3. |